{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T01:27:50Z","timestamp":1784165270030,"version":"3.55.0"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,12,4]],"date-time":"2025-12-04T00:00:00Z","timestamp":1764806400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,12,4]],"date-time":"2025-12-04T00:00:00Z","timestamp":1764806400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100009827","name":"Alexandria University","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100009827","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Recent Mpox outbreaks in non-endemic countries have highlighted the importance of global health preparedness. Combined national survey and pooled analysis were conducted to assess the knowledge and attitudes of healthcare workers (HCWs) toward Mpox in Egypt and the Arab region. An online survey was distributed to HCWs in Egypt, and a literature search of PubMed and other sources was performed to identify relevant studies from Arab countries. Descriptive statistics were utilized for all variables, with chi-square and t-tests used for comparisons. A random-effects meta-analysis was performed, with heterogeneity assessed using the I\n                    <jats:sup>2<\/jats:sup>\n                    statistic. Subgroup analyses were conducted to explore factors of heterogeneity. A total of 399 eligible HCWs from various Egyptian health facilities were included. The mean age of participants was 35.6 \u00b1 7.1 years; the majority were female, married, pharmacists, and had at least five years of experience. The survey revealed that only 37.6% of Egyptian HCWs had good knowledge of Mpox, while 97.9% held positive attitudes. The meta-analysis of 30 studies from Arab countries including both HCWs and the general population, showed a pooled proportion of 35% (95% CI: 31%\u201339%) for good knowledge and 48% (95% CI: 37%\u201359%) for positive attitude. A higher positive attitude was significantly associated with female gender and HCWs. Significant knowledge gaps regarding Mpox exist among HCWs in Egypt and the wider Arab region, despite generally positive attitudes. This underscores an urgent need to update medical curricula, implement continuous educational programs and launch nationwide awareness campaigns.\n                  <\/jats:p>","DOI":"10.1038\/s41598-025-28446-z","type":"journal-article","created":{"date-parts":[[2025,12,4]],"date-time":"2025-12-04T10:09:08Z","timestamp":1764842948000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Assessment of Mpox knowledge and attitudes among health workers in Egypt and Arab countries based on a national survey and a meta-analysis"],"prefix":"10.1038","volume":"15","author":[{"given":"Neamat Hamdy","family":"Elsawy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rasha","family":"Ashmawy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alaa Abd Elkader Abd Elhady","family":"Elmallah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moshira Mansour Abd","family":"Ellatif","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah Magdy Amin","family":"Mokhtar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramzeya Mohamed","family":"Abdelwahab","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samar Saeed Abdo","family":"Elsronbaw","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aisha","family":"Elsharkawy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ehab","family":"Kamal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marwa Rashad","family":"Salem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,12,4]]},"reference":[{"key":"28446_CR1","doi-asserted-by":"crossref","unstructured":"Ghazy, R.M., Hussein, M., Abdu, S.M.M., El-sayed Ellakwa, D., Tolba, M.M., Youssef, N. et al. The intention of Egyptian healthcare workers to take the monkeypox vaccine: is urgent action required? BMC Health Serv. Res. 24(1) (2024).","DOI":"10.1186\/s12913-024-11147-0"},{"issue":"8","key":"28446_CR2","doi-asserted-by":"publisher","first-page":"679","DOI":"10.1056\/NEJMoa2207323","volume":"387","author":"JP Thornhill","year":"2022","unstructured":"Thornhill, J. P. et al. Monkeypox virus infection in humans across 16 countries \u2014 april\u2013june 2022. New Engl. J. Med. 387(8), 679\u201391 (2022).","journal-title":"New Engl. J. Med."},{"key":"28446_CR3","doi-asserted-by":"crossref","unstructured":"Alshahrani, N.Z., Algethami, M.R., Alarifi, A.M., Alzahrani, F., Alshehri, E.A., Alshehri, A.M. et al. Knowledge and attitude regarding monkeypox virus among physicians in Saudi Arabia: A cross-sectional study. Vaccines (Basel). 10(12) (2022).","DOI":"10.3390\/vaccines10122099"},{"key":"28446_CR4","unstructured":"Multi-country monkeypox outbreak in non-endemic countries: Update [Internet]. https:\/\/www.who.int\/emergencies\/disease-outbreak-news\/item\/2022-DON388 (2025)."},{"key":"28446_CR5","unstructured":"Global Mpox Trends [Internet]. https:\/\/worldhealthorg.shinyapps.io\/mpx_global\/_w_2983ef23f79340279b4d1e454c099ffa\/#sec-afr (2025)."},{"issue":"11","key":"28446_CR6","doi-asserted-by":"publisher","first-page":"1191699","DOI":"10.3389\/fpubh.2023.1191699","volume":"6","author":"H Zhang","year":"2023","unstructured":"Zhang, H. et al. Knowledge, attitude, and practice of healthcare workers on early gastrointestinal cancer in China. Front. Pub. Health. 6(11), 1191699 (2023).","journal-title":"Front. Pub. Health."},{"key":"28446_CR7","doi-asserted-by":"crossref","unstructured":"Alsanafi, M., Al-Mahzoum, K., Sallam, M. Monkeypox knowledge and confidence in diagnosis and management with evaluation of emerging virus infection conspiracies among health professionals in Kuwait. Pathogens 11(9) (2022).","DOI":"10.3390\/pathogens11090994"},{"key":"28446_CR8","doi-asserted-by":"crossref","unstructured":"Khattab sally, Nemr, N.N., Kishk, R.M., Mohamed, H.M., Nemr, N.N., El-Ghazaly, A.A. et al. Knowledge and attitude towards Mpox among healthcare workers: An intervention study. Microbes and infectious diseases. 0(0) 0\u20130 (2024).","DOI":"10.21608\/mid.2024.297060.1991"},{"key":"28446_CR9","doi-asserted-by":"crossref","unstructured":"Malaeb, D., Sallam, M., Salim, N.A., Dabbous, M., Younes, S., Nasrallah, Y. et al. Knowledge, attitude and conspiracy beliefs of healthcare workers in Lebanon towards Monkeypox. Trop. Med. Infect. Dis. 8(2) (2023).","DOI":"10.3390\/tropicalmed8020081"},{"key":"28446_CR10","doi-asserted-by":"crossref","unstructured":"Ricc\u00f2, M., Ferraro, P., Camisa, V., Satta, E., Zaniboni, A., Ranzieri, S. et al. When a neglected tropical disease goes global: Knowledge, attitudes and practices of italian physicians towards Monkeypox, preliminary results. Trop. Med. Infect. Dis. 7(7) (2022).","DOI":"10.3390\/tropicalmed7070135"},{"key":"28446_CR11","doi-asserted-by":"crossref","unstructured":"Mohamed, M.G., Islam, M.R., Ahmed, S.K., Khalaf, S.A., Abdelall, H.A., Mahmood, K.A. et al. Assessment of knowledge, attitude, anxiety level and perceived mental healthcare needs toward mpox infection among nursing students: A multi-center cross-sectional study. Glob. 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Vaccine X 20 100527 https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2590136224001001 (2024).","DOI":"10.1016\/j.jvacx.2024.100527"},{"key":"28446_CR16","doi-asserted-by":"crossref","unstructured":"Eysenbach, G. Improving the quality of web surveys: The checklist for reporting results of internet E-surveys (CHERRIES). J. Med. Int. Res. 6 (JMIR Publications Inc., 2004).","DOI":"10.2196\/jmir.6.3.e34"},{"key":"28446_CR17","doi-asserted-by":"publisher","first-page":"215013272110133","DOI":"10.1177\/21501327211013303","volume":"12","author":"S Fares","year":"2021","unstructured":"Fares, S., Elmnyer, M. M., Mohamed, S. S. & Elsayed, R. COVID-19 vaccination perception and attitude among healthcare workers in Egypt. J. Prim. Care Commun. Health. 12, 21501327211013304 (2021).","journal-title":"J. Prim. Care Commun. Health."},{"key":"28446_CR18","doi-asserted-by":"crossref","unstructured":"Sobaikhi, N.H., Alshahrani, N.Z., Hazazi, R.S., Al-Musawa, H.I., Jarram, R.E., Alabah, A.E. et al. Health workers\u2019 knowledge and attitude towards Monkeypox in southwestern Saudi Arabia: A cross-sectional study. Diseases. 11(2) (2023).","DOI":"10.3390\/diseases11020081"},{"key":"28446_CR19","doi-asserted-by":"crossref","unstructured":"Jahromi, A.S., Jokar, M., Sharifi, N., Kashkooli, S., Rahmanian, K., Rahmanian, V. Global knowledge and attitudes towards mpox (monkeypox) among healthcare workers: A systematic review and meta-analysis. 16 487\u201398 (International Health, Oxford University Press, 2024).","DOI":"10.1093\/inthealth\/ihad094"},{"key":"28446_CR20","doi-asserted-by":"crossref","unstructured":"Ahmed, S.K., Abdulqadir, S.O., Omar, R.M., Abdullah, A.J., Rahman, H.A., Hussein, S.H. et al. Knowledge, attitude and worry in the Kurdistan region of Iraq during the Mpox (Monkeypox) Outbreak in 2022: An online cross-sectional study. Vaccines (Basel). 11(3) (2023).","DOI":"10.3390\/vaccines11030610"},{"issue":"1","key":"28446_CR21","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1186\/s12879-024-09184-5","volume":"24","author":"SK Das","year":"2024","unstructured":"Das, S. K. et al. Socio-demographic determinants of the knowledge of Monkeypox Virus among the general public: A cross-sectional study in a tertiary care center in Nepal. BMC Infect. Dis. 24(1), 295 (2024).","journal-title":"BMC Infect. Dis."},{"key":"28446_CR22","doi-asserted-by":"crossref","unstructured":"Sahin, T.K., Erul, E., Aksun, M.S., Sonmezer, M.C., Unal, S., Akova, M. Knowledge and attitudes of turkish physicians towards human Monkeypox disease and related vaccination: A cross-sectional study. 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Pract. 3(6), 179\u201393 (2024).","journal-title":"Helwan Int. J. Nurs. Res. Pract."},{"issue":"July","key":"28446_CR28","first-page":"1","volume":"11","author":"S Abd ElHafeez","year":"2023","unstructured":"Abd ElHafeez, S. et al. Assessing disparities in medical students\u2019 knowledge and attitude about monkeypox: A cross-sectional study of 27 countries across three continents. Front. Pub. Health. 11(July), 1\u201314 (2023).","journal-title":"Front. Pub. Health."},{"key":"28446_CR29","doi-asserted-by":"crossref","unstructured":"Tanashat, M., Altobaishat, O., Sharaf, A., Hossam El Din Moawad, M., Al-Jafari, M., Nashwan, A.J. Assessment of the knowledge, attitude, and perception of the world\u2019s population towards monkeypox and its vaccines: A systematic review and descriptive analysis of cross-sectional studies. Vaccine: X. 20 (Elsevier Ltd, 2024).","DOI":"10.1016\/j.jvacx.2024.100527"},{"key":"28446_CR30","doi-asserted-by":"publisher","unstructured":"Rata Mohan, D.S., Jawahir, S., Manual, A., Abdul Mutalib, N.E., Mohd Noh, S.N., Ab Rahim, I., et al. Gender differences in health-seeking behaviour: Insights from the national health and morbidity survey 2019. BMC Health. Serv. Res. 25(1) 1 13 https:\/\/bmchealthservres.biomedcentral.com\/articles\/https:\/\/doi.org\/10.1186\/s12913-025-13020-0 (2025).","DOI":"10.1186\/s12913-025-13020-0"}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-28446-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-28446-z","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-28446-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,5]],"date-time":"2025-12-05T09:51:27Z","timestamp":1764928287000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-28446-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,4]]},"references-count":30,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["28446"],"URL":"https:\/\/doi.org\/10.1038\/s41598-025-28446-z","relation":{},"ISSN":["2045-2322"],"issn-type":[{"value":"2045-2322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,4]]},"assertion":[{"value":"22 July 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 November 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 December 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The study protocol was reviewed and approved by the Ethical Committee of the Ministry of Health and Population (MoHP), Egypt, under approval number\n                      (8-2023\/13)\n                      . Participation was entirely voluntary, and informed consent was obtained electronically at the beginning of the survey. If a participant chose not to provide consent, the survey automatically terminated. Strict confidentiality and anonymity were ensured throughout all stages of data collection, entry, and analysis, with no personal identifiable information collected or stored.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics"}}],"article-number":"43249"}}