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While motion artifacts are well-known challenges in dynamic settings,\n                    <jats:italic>suboptimal skin-sensor contact in sedentary conditions<\/jats:italic>\n                    -\n                    <jats:italic>an important issue often overlooked in existing literature<\/jats:italic>\n                    - can distort PPG signal morphology, leading to the loss or shift of essential waveform features and therefore degrading sensing performance. In this work, we propose a deep learning-based framework that transforms\n                    <jats:underline>C<\/jats:underline>\n                    ontact\n                    <jats:underline>P<\/jats:underline>\n                    ressure-distorted\n                    <jats:underline>PPG<\/jats:underline>\n                    signals into ones with the ideal morphology, known as CP-PPG. CP-PPG incorporates a well-crafted data processing pipeline and an adversarially trained deep generative model, together with a custom PPG-aware loss function. We validated CP-PPG through comprehensive evaluations, including 1) morphology transformation performance, 2) downstream physiological monitoring performance on public datasets, and 3) in-the-wild performance. Extensive experiments demonstrate substantial and consistent improvements in signal fidelity (Mean Absolute Error: 0.09, 40% improvement over the original signal) as well as downstream performance across all evaluations in Heart Rate (HR), Heart Rate Variability (HRV), Respiration Rate (RR), and Blood Pressure (BP) estimation (on average, 21% improvement in HR; 41-46% in HRV; 6% in RR; and 4-5% in BP). These findings highlight the critical importance of addressing skin-sensor contact issues for accurate and reliable PPG-based physiological monitoring. Our implementation is publicly available at:\n                    <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"https:\/\/github.com\/manhph2211\/CP-PPG\" ext-link-type=\"uri\">https:\/\/github.com\/manhph2211\/CP-PPG<\/jats:ext-link>\n                    .\n                  <\/jats:p>","DOI":"10.1038\/s41598-025-31883-5","type":"journal-article","created":{"date-parts":[[2025,12,17]],"date-time":"2025-12-17T17:35:55Z","timestamp":1765992955000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Reliable wrist PPG monitoring by mitigating poor skin sensor contact"],"prefix":"10.1038","volume":"15","author":[{"given":"Hung Manh","family":"Pham","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew Yiwen","family":"Ho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiming","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dimitris","family":"Spathis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aaqib","family":"Saeed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,12,17]]},"reference":[{"key":"31883_CR1","doi-asserted-by":"publisher","first-page":"6560","DOI":"10.1109\/JSEN.2019.2914166","volume":"19","author":"D Biswas","year":"2019","unstructured":"Biswas, D., Sim\u00f5es-Capela, N., Van Hoof, C. & Van Helleputte, N. 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