{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T18:06:27Z","timestamp":1793815587623,"version":"4.6.1"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T00:00:00Z","timestamp":1767744000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T00:00:00Z","timestamp":1769644800000},"content-version":"vor","delay-in-days":22,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"DOI":"10.1038\/s41598-025-34160-7","type":"journal-article","created":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T07:44:27Z","timestamp":1767771867000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Transformer-assisted convolutional feature extraction with deep representation learning models for lung and colon cancer diagnosis using histopathological images"],"prefix":"10.1038","volume":"16","author":[{"given":"S.","family":"Jayanthi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Inderjeet","family":"Kaur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Laxmi Lydia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K. Vijaya","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gyanendra Prasad","family":"Joshi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Woong","family":"Cho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,1,7]]},"reference":[{"key":"34160_CR1","doi-asserted-by":"crossref","unstructured":"Talukder, M. A. et al. Machine learning-based lung and colon cancer detection using deep feature extraction and ensemble learning. Expert Syst. Appl. 205, 117695 (2022).","DOI":"10.1016\/j.eswa.2022.117695"},{"key":"34160_CR2","doi-asserted-by":"crossref","unstructured":"Wahid, R. R., Nisa\u2019, C., Amaliyah, R. P. & Puspaningrum, E. Y. February. Lung and colon cancer detection with convolutional neural networks on histopathological images. AIP Conf. Proc. 2654, 020020 (2023).","DOI":"10.1063\/5.0114327"},{"key":"34160_CR3","doi-asserted-by":"crossref","unstructured":"Masud, M., Sikder, N., Nahid, A. A., Bairagi, A. K. & AlZain, M. A. A machine learning approach to diagnosing lung and colon cancer using a deep learning-based classification framework. Sensors. 21(3), 748 (2021).","DOI":"10.3390\/s21030748"},{"key":"34160_CR4","doi-asserted-by":"crossref","unstructured":"Akinyemi, J. D., Akinola, A. A., Adekunle, O. O., Adetiloye, T. O. & Dansu, E. J. Lung and colon cancer detection from CT images using deep learning. Mach. Graph. Vision. 32 (2023).","DOI":"10.22630\/MGV.2023.32.1.5"},{"key":"34160_CR5","doi-asserted-by":"crossref","unstructured":"Patharia, P., Sethy, P. K. & Nanthaamornphong, A. Advancements and Challenges in the image-based diagnosis of lung and colon cancer: A comprehensive review. Cancer Inf. 23, 11769351241290608. (2024).","DOI":"10.1177\/11769351241290608"},{"key":"34160_CR6","doi-asserted-by":"crossref","unstructured":"Kaya, S. I., Ozcelikay, G., Mollarasouli, F., Bakirhan, N. K. & Ozkan, S. A. Recent achievements and challenges on nanomaterial based electrochemical biosensors for the detection of colon and lung cancer biomarkers. Sens. Actuators B: Chem. 351, 130856 (2022).","DOI":"10.1016\/j.snb.2021.130856"},{"issue":"3","key":"34160_CR7","doi-asserted-by":"publisher","first-page":"729","DOI":"10.1007\/s13246-022-01139-x","volume":"45","author":"A Hage Chehade","year":"2022","unstructured":"Hage Chehade, A., Abdallah, N., Marion, J. M., Oueidat, M. & Chauvet, P. Lung and colon cancer classification using medical imaging: A feature engineering approach. Phys. Eng. Sci. Med. 45 (3), 729\u2013746 (2022).","journal-title":"Phys. Eng. Sci. Med."},{"key":"34160_CR8","doi-asserted-by":"crossref","unstructured":"Kumar, R. R. & Gupta, S. October. Enhancing Lung and Colon Cancer Detection Through Convolutional Neural Networks. In 2024 4th International Conference on Sustainable Expert Systems (ICSES) (pp. 1440\u20131445). IEEE. (2024).","DOI":"10.1109\/ICSES63445.2024.10763031"},{"key":"34160_CR9","doi-asserted-by":"crossref","unstructured":"Narayanan, V., Nithya, P. & Sathya, M. Effective lung cancer detection using deep learning network. J. Cognit. Human-Comput. Interact. 2, 15 (2023).","DOI":"10.54216\/JCHCI.050202"},{"key":"34160_CR10","doi-asserted-by":"crossref","unstructured":"Ozdemir, B., Aslan, E. & Pacal, I. Attention Enhanced InceptionNeXt Based Hybrid Deep Learning Model for Lung Cancer Detection (IEEE Access, 2025).","DOI":"10.1109\/ACCESS.2025.3539122"},{"key":"34160_CR11","doi-asserted-by":"crossref","unstructured":"Attallah, O. Multidomain feature incorporation of lightweight convolutional neural networks and handcrafted features for lung and colon cancer diagnosis. Technologies. 13, 173 (2025).","DOI":"10.3390\/technologies13050173"},{"key":"34160_CR12","first-page":"100609","volume":"29","author":"MVR Vittal","year":"2025","unstructured":"Vittal, M. V. R. Advanced colon cancer detection: Integrating context-aware multi-image fusion (Camif) in a multistage framework. Egypt. Inf. J. 29, 100609 (2025).","journal-title":"Egypt. Inf. J."},{"issue":"1","key":"34160_CR13","first-page":"92","volume":"11","author":"S Dash","year":"2025","unstructured":"Dash, S., Padhy, S., Suman, P. & Das, R. K. Enhancing lung cancer diagnosis through CT scan image analysis using Mask-EffNet. Eng. Access. 11 (1), 92\u2013107 (2025).","journal-title":"Eng. Access."},{"key":"34160_CR14","doi-asserted-by":"crossref","unstructured":"Alsulami, A. A., Albarakati, A., Al-Ghamdi, A. A. M. & Ragab, M. Identification of anomalies in lung and colon cancer using computer vision-based Swin Transformer with ensemble model on histopathological images. Bioengineering. 11, 978 (2024).","DOI":"10.3390\/bioengineering11100978"},{"key":"34160_CR15","doi-asserted-by":"publisher","first-page":"94705","DOI":"10.1109\/ACCESS.2023.3309711","volume":"11","author":"M Obayya","year":"2023","unstructured":"Obayya, M. et al. Biomedical image analysis for colon and lung cancer detection using tuna swarm algorithm with deep learning model. IEEE Access. 11, 94705\u201394712 (2023).","journal-title":"IEEE Access."},{"key":"34160_CR16","first-page":"178","volume":"2022","author":"AA Kassem","year":"2023","unstructured":"Kassem, A. A. Snake optimization with deep learning enabled disease detection model for colorectal cancer. J. Smart Internet Things. 2022, 178\u2013195 (2023).","journal-title":"J. Smart Internet Things"},{"key":"34160_CR17","doi-asserted-by":"publisher","first-page":"107972","DOI":"10.1109\/ACCESS.2023.3313508","volume":"11","author":"M Ragab","year":"2023","unstructured":"Ragab, M. et al. Self-upgraded Cat mouse optimizer with machine learning driven lung cancer classification on computed tomography imaging. IEEE Access. 11, 107972\u2013107981 (2023).","journal-title":"IEEE Access."},{"key":"34160_CR18","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1016\/j.procs.2020.06.003","volume":"173","author":"A Kumar","year":"2020","unstructured":"Kumar, A. & Raheja, S. Edge detection using guided image filtering and enhanced ant colony optimization. Procedia Comput. Sci. 173, 8\u201317 (2020).","journal-title":"Procedia Comput. Sci."},{"key":"34160_CR19","unstructured":"Bamini, A., Kumar, J. N. A., Jayapratha, C. & Govindaprabhu, G. B. Revolutionizing Monkey pox diagnosis: A cutting-edge deep learning pipeline for advanced lesion segmentation and classification using CoAtNet."},{"key":"34160_CR20","doi-asserted-by":"crossref","unstructured":"Muksimova, S., Umirzakova, S., Baltayev, J. & Cho, Y. I. Rl-cervix. net: A hybrid lightweight model integrating reinforcement learning for cervical cell classification. Diagnostics. 15(3), 364 (2025).","DOI":"10.3390\/diagnostics15030364"},{"issue":"4","key":"34160_CR21","doi-asserted-by":"publisher","first-page":"e0321637","DOI":"10.1371\/journal.pone.0321637","volume":"20","author":"Q Wang","year":"2025","unstructured":"Wang, Q., Tang, M. & Shi, P. Depth prediction of urban waterlogging based on BiTCN-GRU modeling. PloS One. 20 (4), e0321637 (2025).","journal-title":"PloS One"},{"key":"34160_CR22","doi-asserted-by":"crossref","unstructured":"Zhang, C., Hu, Z., Xu, L. & Zhao, Y. A YOLOv7 incorporating the Adan optimizer based corn pests identification method. Front. Plant Sci. 14, 1174556. (2023).","DOI":"10.3389\/fpls.2023.1174556"},{"key":"34160_CR23","unstructured":"https:\/\/www.kaggle.com\/datasets\/andrewmvd\/lung-and-colon-cancer-histopathological-images"},{"key":"34160_CR24","doi-asserted-by":"publisher","first-page":"25657","DOI":"10.1109\/ACCESS.2022.3150924","volume":"10","author":"S Mehmood","year":"2022","unstructured":"Mehmood, S. et al. Malignancy detection in lung and colon histopathology images using transfer learning with class selective image processing. IEEE Access. 10, 25657\u201325668 (2022).","journal-title":"IEEE Access."},{"key":"34160_CR25","unstructured":"https:\/\/www.kaggle.com\/datasets\/biplobdey\/lung-and-colon-cancer\/data"},{"key":"34160_CR26","doi-asserted-by":"crossref","unstructured":"Uddin, A. H. et al. Colon and lung cancer classification from multi-modal images using resilient and efficient neural network architectures. Heliyon. 10(9). (2024).","DOI":"10.1016\/j.heliyon.2024.e30625"},{"key":"34160_CR27","unstructured":"https:\/\/www.kaggle.com\/datasets\/rhhossen220\/lung-and-colon-cancer-dataset\/data"},{"key":"34160_CR28","doi-asserted-by":"publisher","first-page":"110164","DOI":"10.1109\/ACCESS.2023.3321686","volume":"11","author":"MAM Provath","year":"2023","unstructured":"Provath, M. A. M., Deb, K., Dhar, P. K. & Shimamura, T. Classification of lung and colon cancer histopathological images using global context attention based convolutional neural network. IEEE Access. 11, 110164\u2013110183 (2023).","journal-title":"IEEE Access."},{"key":"34160_CR29","doi-asserted-by":"crossref","unstructured":"Raza, R. et al. Lung-EffNet: Lung cancer classification using EfficientNet from CT-scan images. Engi. Appl. Artifi. Intell. 126, 106902. (2023).","DOI":"10.1016\/j.engappai.2023.106902"}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-34160-7","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-34160-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-34160-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T09:55:22Z","timestamp":1769680522000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-34160-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,7]]},"references-count":29,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["34160"],"URL":"https:\/\/doi.org\/10.1038\/s41598-025-34160-7","relation":{},"ISSN":["2045-2322"],"issn-type":[{"value":"2045-2322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,7]]},"assertion":[{"value":"16 July 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 December 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 January 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"4026"}}