{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T21:28:39Z","timestamp":1769808519406,"version":"3.49.0"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T00:00:00Z","timestamp":1769558400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T00:00:00Z","timestamp":1769731200000},"content-version":"vor","delay-in-days":2,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Infantile colic is an important problem encountered during the first months of life. This study investigated the effect of infantile colic training provided to parents on the severity of neonatal infantile colic and the duration of crying. The research used a one-group pretest\u2013posttest design. The study was conducted among the mothers and fathers of newborns who attended a Family Health Center between May and October 2024 and were diagnosed with infantile colic. A power analysis was conducted, and the sample consisted of 60 parents. Parents received infantile colic training in a single session, and its effectiveness was evaluated at two different times. Data were obtained via a questionnaire that included a sociodemographic form and the Infantile Colic Scale. The crying times of the newborns were recorded based on the information provided by the parents. Statistically significant differences in the Infantile Colic Scale scores were not found in mothers after the training; however, significant differences were observed in the first post-education assessment of fathers and between the parents\u2019 first and second assessments. The mean duration of infant crying after the training was found to have a high effect size. After the training, it was found that the severity of newborn infantile colic and the duration of crying decreased. This training is an effective intervention for neonatal infantile colic.<\/jats:p>","DOI":"10.1038\/s41598-025-34344-1","type":"journal-article","created":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T19:15:06Z","timestamp":1769627706000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The effect of infantile colic training given to parents on the neonatal infantile colic level and crying duration"],"prefix":"10.1038","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4589-7264","authenticated-orcid":false,"given":"Serap","family":"\u00d6zdemir","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-4031-6215","authenticated-orcid":false,"given":"Gizem","family":"Yilmaz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-5385-0231","authenticated-orcid":false,"given":"Nisa Nur","family":"\u00c7elik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-1866-2159","authenticated-orcid":false,"given":"Fatmag\u00fcl","family":"Bayram","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,1,28]]},"reference":[{"issue":"9","key":"34344_CR1","doi-asserted-by":"publisher","first-page":"1733","DOI":"10.1111\/apa.15247","volume":"109","author":"A Hjern","year":"2020","unstructured":"Hjern, A., Lindblom, K., Reuter, A. & Silfverdal, S. A. A systematic review of prevention and treatment of infantile colic. Acta Paediatr. 109(9), 1733\u20131744 (2020).","journal-title":"Acta Paediatr."},{"issue":"1","key":"34344_CR2","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1186\/s12884-025-07360-2","volume":"25","author":"A Radwan","year":"2025","unstructured":"Radwan, A. et al. Maternal knowledge and practices regarding infantile colic in Palestine: A need for enhanced education and awareness. BMC Pregnancy Childbirth 25(1), 223 (2025).","journal-title":"BMC Pregnancy Childbirth"},{"issue":"8","key":"34344_CR3","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1038\/s41575-018-0008-7","volume":"15","author":"J Zeevenhooven","year":"2018","unstructured":"Zeevenhooven, J., Browne, P. D., L\u2019Hoir, M. P., de Weerth, C. & Benninga, M. A. Infant colic: Mechanisms and management. Nat. Rev. Gastroenterol. Hepatol. 15(8), 479\u2013496 (2018).","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"issue":"5","key":"34344_CR4","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1542\/peds.14.5.421","volume":"14","author":"MA Wessel","year":"1954","unstructured":"Wessel, M. A., Cobb, J. C., Jackson, E. B., Harris, G. S. Jr. & Detwiler, A. C. Paroxysmal fussing in infancy, sometimes called \u201ccolic\u201d. Pediatrics 14(5), 421\u2013435 (1954).","journal-title":"Pediatrics"},{"key":"34344_CR5","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2021.778747","volume":"9","author":"L Muhardi","year":"2022","unstructured":"Muhardi, L. et al. A narrative review on the update in the prevalence of infantile colic, regurgitation, and constipation in young children: Implications of the ROME IV criteria. Front. Pediatr. 9, 778747 (2022).","journal-title":"Front. Pediatr."},{"issue":"8","key":"34344_CR6","doi-asserted-by":"publisher","first-page":"1302","DOI":"10.3390\/nu17081302","volume":"17","author":"JM Brown","year":"2025","unstructured":"Brown, J. M. et al. Infant colic symptoms and amino acid formula: Insights from a prospective cohort study. Nutrients 17(8), 1302 (2025).","journal-title":"Nutrients"},{"issue":"5","key":"34344_CR7","doi-asserted-by":"publisher","first-page":"1537","DOI":"10.1038\/s41390-024-03518-4","volume":"97","author":"KM Switkowski","year":"2024","unstructured":"Switkowski, K. M. et al. Early-life risk factors for both infant colic and excessive crying without colic. Pediatr. Res. 97(5), 1537\u20131545 (2024).","journal-title":"Pediatr. Res."},{"issue":"3","key":"34344_CR8","doi-asserted-by":"publisher","first-page":"615","DOI":"10.3390\/nu15030615","volume":"15","author":"F Indrio","year":"2023","unstructured":"Indrio, F., Dargenio, V. N., Francavilla, R., Szajewska, H. & Vandenplas, Y. Infantile colic and long-term outcomes in childhood: A narrative synthesis of the evidence. Nutrients 15(3), 615 (2023).","journal-title":"Nutrients"},{"key":"34344_CR9","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD012459.pub2","author":"M Gordon","year":"2019","unstructured":"Gordon, M., Gohil, J. & Banks, S. S. Parent training programmes for managing infantile colic. Cochrane Database Syst. Rev. https:\/\/doi.org\/10.1002\/14651858.CD012459.pub2 (2019).","journal-title":"Cochrane Database Syst. Rev."},{"issue":"3","key":"34344_CR10","first-page":"125","volume":"4","author":"SA Be\u015firik","year":"2021","unstructured":"Be\u015firik, S. A. Colic scale scores and associated factors in infants diagnosed with infantile colic. Turk. J. Health Sci. Life 4(3), 125\u2013132 (2021).","journal-title":"Turk. J. Health Sci. Life"},{"key":"34344_CR11","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1016\/j.pediatrneurol.2025.06.020","volume":"170","author":"T Hikita","year":"2025","unstructured":"Hikita, T., Isozaki, K., Ogita, K., Hikita, F. & Hikita, H. Prevalence of infantile colic and associated factors. Pediatr. Neurol. 170, 113\u2013117 (2025).","journal-title":"Pediatr. Neurol."},{"issue":"3","key":"34344_CR12","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1501\/Tipfak_0000000938","volume":"69","author":"F Orhon","year":"2016","unstructured":"Orhon, F. & Filiz, F. \u0130nfantil kolik tan\u0131 ve tedavisinde g\u00fcncel yakla\u015f\u0131mlar. Ankara \u00dcniversitesi T\u0131p Fak\u00fcltesi Mecmuas\u0131 69(3), 159\u2013166 (2016).","journal-title":"Ankara \u00dcniversitesi T\u0131p Fak\u00fcltesi Mecmuas\u0131"},{"issue":"2","key":"34344_CR13","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2019-035405","volume":"10","author":"J Ellwood","year":"2020","unstructured":"Ellwood, J., Draper-Rodi, J. & Carnes, D. Comparison of common interventions for the treatment of infantile colic: A systematic review of reviews and guidelines. BMJ Open 10(2), e035405 (2020).","journal-title":"BMJ Open"},{"key":"34344_CR14","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1007\/978-3-031-58572-2_4","volume":"19","author":"F Indrio","year":"2024","unstructured":"Indrio, F. & Dargenio, V. N. Preventing and treating colic: An update. Probiotics Child Gastrointest. Health: Adv. Microbiol., Infect. Dis. Public Health 19, 59\u201378 (2024).","journal-title":"Probiotics Child Gastrointest. Health: Adv. Microbiol., Infect. Dis. Public Health"},{"issue":"6","key":"34344_CR15","doi-asserted-by":"publisher","first-page":"653","DOI":"10.1111\/jpc.13858","volume":"54","author":"J McGann","year":"2018","unstructured":"McGann, J. et al. Caring for crying babies: A mixed-methods study to understand factors influencing nurses\u2019 and doctors\u2019 management of infant colic. J. Paediatr. Child Health 54(6), 653\u2013660 (2018).","journal-title":"J. Paediatr. Child Health"},{"key":"34344_CR16","unstructured":"Johnson, J. Educating parents about infantile colic and the gastrointestinal microbiome. Int. J. Birth Parent Educ. 11 (3), (2024)."},{"issue":"1","key":"34344_CR17","first-page":"8","volume":"5","author":"B Mutlu","year":"2020","unstructured":"Mutlu, B., Erkut, Z., Avc\u0131, \u015e, Girgin, S. S. & G\u00f6nen, \u0130. The practices used by mothers to infantile colic and their perceptions on the benefits of the practices. Online Turk. J. Health Sci. 5(1), 8\u201316 (2020).","journal-title":"Online Turk. J. Health Sci."},{"key":"34344_CR18","doi-asserted-by":"publisher","first-page":"390","DOI":"10.1016\/j.pedn.2025.07.003","volume":"84","author":"GS Ertem","year":"2025","unstructured":"Ertem, G. S. & \u00d6zyaz\u0131c\u0131o\u011flu, N. Effects of colic massage and kangaroo care on infantile colic pain, crying and sleep duration: A randomized controlled trial. J. Pediatr. Nurs. 84, 390\u2013396 (2025).","journal-title":"J. Pediatr. Nurs."},{"issue":"6","key":"34344_CR19","doi-asserted-by":"publisher","first-page":"584","DOI":"10.1089\/acm.2017.0315","volume":"24","author":"S Icke","year":"2018","unstructured":"Icke, S. & Genc, R. Effect of reflexology on infantile colic. J. Altern. Complement. Med. 24(6), 584\u2013588 (2018).","journal-title":"J. Altern. Complement. Med."},{"key":"34344_CR20","doi-asserted-by":"publisher","DOI":"10.2147\/PHMT.S185214","author":"S Mansouri","year":"2018","unstructured":"Mansouri, S. et al. A placebo-controlled clinical trial to evaluate the effectiveness of massaging on infantile colic using a random-effects joint model. Pediatr. Health, Med. Ther. https:\/\/doi.org\/10.2147\/PHMT.S185214 (2018).","journal-title":"Pediatr. Health, Med. Ther."},{"issue":"3","key":"34344_CR21","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1136\/acupmed-2016-011208","volume":"35","author":"K Landgren","year":"2017","unstructured":"Landgren, K. & Hallstr\u00f6m, I. Effect of minimal acupuncture for infantile colic: A multicentre, three-armed, single-blind, randomised controlled trial (ACU-COL). Acupunct. Med. 35(3), 171\u2013179 (2017).","journal-title":"Acupunct. Med."},{"issue":"4","key":"34344_CR22","doi-asserted-by":"publisher","first-page":"861","DOI":"10.1111\/scs.12790","volume":"34","author":"L Hannula","year":"2020","unstructured":"Hannula, L., Puukka, P., Asunmaa, M. & M\u00e4kij\u00e4rvi, M. A pilot study of parents\u2019 experiences of reflexology treatment for infants with colic in Finland. Scand. J. Caring Sci. 34(4), 861\u2013870 (2020).","journal-title":"Scand. J. Caring Sci."},{"key":"34344_CR23","doi-asserted-by":"publisher","first-page":"102164","DOI":"10.1016\/j.ctim.2019.07.023","volume":"47","author":"M Castej\u00f3n-Castej\u00f3n","year":"2019","unstructured":"Castej\u00f3n-Castej\u00f3n, M. et al. Effectiveness of craniosacral therapy in the treatment of infantile colic. A randomized controlled trial. Complement. Ther. Med. 47, 102164 (2019).","journal-title":"Complement. Ther. Med."},{"issue":"3\u20134","key":"34344_CR24","doi-asserted-by":"publisher","first-page":"593","DOI":"10.1111\/jocn.13928","volume":"27","author":"E Sezici","year":"2018","unstructured":"Sezici, E. & Yigit, D. Comparison between swinging and playing of white noise among colicky babies: A paired randomised controlled trial. J. Clin. Nurs. 27(3\u20134), 593\u2013600 (2018).","journal-title":"J. Clin. Nurs."},{"key":"34344_CR25","volume-title":"Colic (Nursing)","author":"J Banks","year":"2021","unstructured":"Banks, J., Rouster, A., Chee, J. & Doerr, C. Colic (Nursing) (StatPearls Publishing, 2021)."},{"key":"34344_CR26","doi-asserted-by":"publisher","first-page":"223","DOI":"10.4274\/jpr.galenos.2019.72687","volume":"7","author":"NA Didi\u015fen","year":"2020","unstructured":"Didi\u015fen, N. A. et al. Infantile colic in infants aged one-six months and the practices of mothers for colic. J. Pediatr. Res. 7, 223\u2013229 (2020).","journal-title":"J. Pediatr. Res."},{"issue":"2","key":"34344_CR27","doi-asserted-by":"publisher","first-page":"145","DOI":"10.21608\/mnj.2024.379243","volume":"11","author":"M El-Bahnasawy","year":"2024","unstructured":"El-Bahnasawy, M., Wady, D. & Abd El Aziz, M. Effect of educational program for mother about care of their infants with infantile colic. Mansoura Nurs. J. 11(2), 145\u2013153 (2024).","journal-title":"Mansoura Nurs. J."},{"issue":"4","key":"34344_CR28","doi-asserted-by":"publisher","first-page":"1149","DOI":"10.3758\/BRM.41.4.1149","volume":"41","author":"F Faul","year":"2009","unstructured":"Faul, F., Erdfelder, E., Buchner, A. & Lang, A.-G. Statistical power analyses using G* Power 3.1: Tests for correlation and regression analyses. Behav. Res. Methods 41(4), 1149\u20131160 (2009).","journal-title":"Behav. Res. Methods"},{"issue":"3","key":"34344_CR29","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1097\/00001610-200305000-00002","volume":"26","author":"MLC Ellett","year":"2003","unstructured":"Ellett, M. L. C. et al. Development and psychometric testing of the infant colic scale. Gastroenterol. Nurs. 26(3), 96\u2013103 (2003).","journal-title":"Gastroenterol. Nurs."},{"issue":"2","key":"34344_CR30","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1097\/01.SGA.0000267925.31803.30","volume":"30","author":"B \u00c7etinkaya","year":"2007","unstructured":"\u00c7etinkaya, B. & Basbakkal, Z. A validity and reliability study investigating the Turkish version of the Infant Colic Scale. Gastroenterol. Nurs. 30(2), 84\u201390 (2007).","journal-title":"Gastroenterol. Nurs."},{"issue":"10","key":"34344_CR31","doi-asserted-by":"publisher","first-page":"569","DOI":"10.1111\/jpc.16646","volume":"60","author":"S Ate\u015fBe\u015firik","year":"2024","unstructured":"Ate\u015fBe\u015firik, S. & Ge\u00e7kil, E. The effect of therapeutic touch on colic symptoms in infantile colic infants: A randomised controlled study. J. Paediatr. Child Health 60(10), 569\u2013578 (2024).","journal-title":"J. Paediatr. Child Health"},{"key":"34344_CR32","doi-asserted-by":"publisher","DOI":"10.4324\/9780203771587","volume-title":"Statistical power analysis for the behavioral sciences","author":"J Cohen","year":"2013","unstructured":"Cohen, J. Statistical power analysis for the behavioral sciences (Routledge, 2013)."}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-34344-1","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-34344-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-34344-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T10:02:16Z","timestamp":1769767336000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-34344-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,28]]},"references-count":32,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["34344"],"URL":"https:\/\/doi.org\/10.1038\/s41598-025-34344-1","relation":{},"ISSN":["2045-2322"],"issn-type":[{"value":"2045-2322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,28]]},"assertion":[{"value":"28 October 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 December 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 January 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Competing interests declared by the corresponding author on behalf of all authors: The authors whose names are listed certify that they have no conflicts of interest regarding personal or professional relationships, nor any financial interests in this manuscript. The authors confirm their specific contributions to the work presented. The authors agree on the conclusions, implications, or opinions stated in the manuscript reported. All authors give consent to the submission and publication of the work. Furthermore, each author certifies that this material or similar material has not been and will not be submitted to or published in any other publication.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Before the study, the informed consent form explaining the purpose of the study and the use of personal data for scientific research was explained to the mothers and the fathers, and their consent was obtained. The Kilis 7 Aralik University Ethics Committee of Non-Interventional Studies evaluated the research, and approval was obtained on February 6th, 2024 (Decision No.: 2024\/01). 06.02.2024. Throughout the research process, actions were taken in accordance with the principles outlined in the Declaration of Helsinki on Human Rights.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Clinical trial number"}}],"article-number":"4233"}}