{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,1,12]],"date-time":"2025-01-12T05:05:00Z","timestamp":1736658300305,"version":"3.32.0"},"reference-count":76,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,1,11]],"date-time":"2025-01-11T00:00:00Z","timestamp":1736553600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,1,11]],"date-time":"2025-01-11T00:00:00Z","timestamp":1736553600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"DOI":"10.1038\/s41598-025-85601-2","type":"journal-article","created":{"date-parts":[[2025,1,11]],"date-time":"2025-01-11T06:55:02Z","timestamp":1736578502000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Isotemporal substitution of physical activity patterns and sitting time with obesity indicators among workers in S\u00e3o Paulo"],"prefix":"10.1038","volume":"15","author":[{"given":"Diego","family":"Sales","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerson","family":"Ferrari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jo\u00e3o Pedro","family":"da Silva Junior","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raiany Rosa","family":"Bergamo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro Paulo","family":"de Oliveira Moda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amauri dos","family":"Santos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mauricio dos","family":"Santos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victor","family":"Matsudo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,1,11]]},"reference":[{"key":"85601_CR1","doi-asserted-by":"publisher","first-page":"12699","DOI":"10.1038\/s41598-022-16934-5","volume":"12","author":"JM Estivaleti","year":"2022","unstructured":"Estivaleti, J. M. et al. Time trends and projected obesity epidemic in Brazilian adults between 2006 and 2030. Sci. Rep. 12, 12699. https:\/\/doi.org\/10.1038\/s41598-022-16934-5 (2022).","journal-title":"Sci. Rep."},{"key":"85601_CR2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(23)02750-2","author":"NH Phelps","year":"2024","unstructured":"Phelps, N. H. et al. Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults. Lancet https:\/\/doi.org\/10.1016\/S0140-6736(23)02750-2 (2024).","journal-title":"Lancet"},{"key":"85601_CR3","doi-asserted-by":"publisher","first-page":"22483","DOI":"10.1038\/s41598-022-26739-1","volume":"12","author":"EAF Nilson","year":"2022","unstructured":"Nilson, E. A. F., Gianicchi, B., Ferrari, G. & Rezende, L. F. M. The projected burden of non-communicable diseases attributable to overweight in Brazil from 2021 to 2030. Sci. Rep. 12, 22483. https:\/\/doi.org\/10.1038\/s41598-022-26739-1 (2022).","journal-title":"Sci. Rep."},{"key":"85601_CR4","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1515\/reveh-2004-19-3-410","volume":"19","author":"F Assis Comaru","year":"2021","unstructured":"Assis Comaru, F. & Faria Westphal, M. Housing, urban development and health in latin America: contrasts, inequalities and challenges. Rev. Environ. Health. 19, 329\u2013346. https:\/\/doi.org\/10.1515\/reveh-2004-19-3-410 (2021).","journal-title":"Rev. Environ. Health"},{"key":"85601_CR5","unstructured":"IBGE. Censo Demogr\u00e1fico. https:\/\/www.ibge.gov.br\/ Accessed March 2022 (2022)."},{"key":"85601_CR6","doi-asserted-by":"publisher","unstructured":"Lima, A. P., Nunes, A., Nicoletti, C. F. & Benatti, F. B. Trend in the prevalence of overweight and obese adults in Sao Paulo, Brazil: analysis between the years 2006 and 2019. Int. J. Environ. Res. Public. Health. 21 https:\/\/doi.org\/10.3390\/ijerph21040502 (2024).","DOI":"10.3390\/ijerph21040502"},{"key":"85601_CR7","doi-asserted-by":"publisher","first-page":"e127","DOI":"10.26633\/RPSP.2018.127","volume":"9","author":"J Greene","year":"2018","unstructured":"Greene, J. & Guanais, F. An examination of socioeconomic equity in health experiences in six latin American and Caribbean countries. Rev. Panam. Salud Publica. 9, 42:e127. https:\/\/doi.org\/10.26633\/RPSP.2018.127 (2018).","journal-title":"Rev. Panam. Salud Publica"},{"key":"85601_CR8","doi-asserted-by":"publisher","first-page":"e183788","DOI":"10.1001\/jamanetworkopen.2018.3788","volume":"1","author":"H Riaz","year":"2018","unstructured":"Riaz, H. et al. Association between obesity and cardiovascular outcomes: a systematic review and meta-analysis of mendelian randomization studies. JAMA Netw. Open. 1, e183788. https:\/\/doi.org\/10.1001\/jamanetworkopen.2018.3788 (2018).","journal-title":"JAMA Netw. Open."},{"key":"85601_CR9","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1186\/s12916-020-01848-8","volume":"19","author":"S Parra-Soto","year":"2021","unstructured":"Parra-Soto, S. et al. Associations of six adiposity-related markers with incidence and mortality from 24 cancers-findings from the UK Biobank prospective cohort study. BMC Med. 19, 7. https:\/\/doi.org\/10.1186\/s12916-020-01848-8 (2021).","journal-title":"BMC Med."},{"key":"85601_CR10","doi-asserted-by":"publisher","first-page":"e13137","DOI":"10.1111\/obr.13137","volume":"22","author":"G O\u2019Donoghue","year":"2021","unstructured":"O\u2019Donoghue, G., Blake, C., Cunningham, C., Lennon, O. & Perrotta, C. What exercise prescription is optimal to improve body composition and cardiorespiratory fitness in adults living with obesity? A network meta-analysis. Obes. Rev. 22, e13137. https:\/\/doi.org\/10.1111\/obr.13137 (2021).","journal-title":"Obes. Rev."},{"key":"85601_CR11","doi-asserted-by":"publisher","first-page":"1451","DOI":"10.1136\/bjsports-2020-102955","volume":"54","author":"FC Bull","year":"2020","unstructured":"Bull, F. C. et al. World Health Organization 2020 guidelines on physical activity and sedentary behaviour. Br. J. Sports Med. 54, 1451\u20131462. https:\/\/doi.org\/10.1136\/bjsports-2020-102955 (2020).","journal-title":"Br. J. Sports Med."},{"key":"85601_CR12","doi-asserted-by":"publisher","first-page":"e1232","DOI":"10.1016\/S2214-109X(24)00150-5","volume":"12","author":"T Strain","year":"2024","unstructured":"Strain, T. et al. National, regional, and global trends in insufficient physical activity among adults from 2000 to 2022: a pooled analysis of 507 population-based surveys with 5.7 million participants. Lancet Glob Health. 12, e1232\u2013e1243. https:\/\/doi.org\/10.1016\/S2214-109X(24)00150-5 (2024).","journal-title":"Lancet Glob Health"},{"key":"85601_CR13","unstructured":"Minist\u00e9rio da Sa\u00fade. Vigitel Brasil 2006\u20132023: vigil\u00e2ncia de fatores de risco e prote\u00e7\u00e3o para doen\u00e7as cr\u00f4nicas por inqu\u00e9rito telef\u00f4nico : estimativas sobre frequ\u00eancia e distribui\u00e7\u00e3o sociodemogr\u00e1fica de pr\u00e1tica de atividade f\u00edsica nas capitais dos 26 estados brasileiros e no Distrito Federal entre 2006 e 2023 : pr\u00e1tica de atividade f\u00edsica. Minist\u00e9rio da Sa\u00fade, Secretaria de Vigil\u00e2ncia em Sa\u00fade e Ambiente, Departamento de An\u00e1lise Epidemiol\u00f3gica e Vigil\u00e2ncia de Doen\u00e7as n\u00e3o Transmiss\u00edveis. \u2013 Bras\u00edlia : Minist\u00e9rio da Sa\u00fade. (2024)."},{"key":"85601_CR14","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1016\/j.clnesp.2022.06.001","volume":"50","author":"EA Silveira","year":"2022","unstructured":"Silveira, E. A. et al. Sedentary behavior, physical inactivity, abdominal obesity and obesity in adults and older adults: a systematic review and meta-analysis. Clin. Nutr. ESPEN. 50, 63\u201373. https:\/\/doi.org\/10.1016\/j.clnesp.2022.06.001 (2022).","journal-title":"Clin. Nutr. ESPEN"},{"key":"85601_CR15","doi-asserted-by":"publisher","first-page":"352","DOI":"10.1007\/s13679-017-0267-6","volume":"6","author":"SJH Biddle","year":"2017","unstructured":"Biddle, S. J. H. et al. Erratum to: screen time, other sedentary behaviours, and obesity risk in adults: a review of reviews. Curr. Obes. Rep. 6, 352. https:\/\/doi.org\/10.1007\/s13679-017-0267-6 (2017).","journal-title":"Curr. Obes. Rep."},{"key":"85601_CR16","doi-asserted-by":"publisher","first-page":"S197","DOI":"10.1139\/apnm-2020-0272","volume":"45","author":"TJ Saunders","year":"2020","unstructured":"Saunders, T. J. et al. Sedentary behaviour and health in adults: an overview of systematic reviews. Appl. Physiol. Nutr. Metab. 45, S197\u2013S217. https:\/\/doi.org\/10.1139\/apnm-2020-0272 (2020).","journal-title":"Appl. Physiol. Nutr. Metab."},{"key":"85601_CR17","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1186\/s12966-024-01593-8","volume":"21","author":"A Kazemi","year":"2024","unstructured":"Kazemi, A. et al. Leisure-time and occupational physical activity and risk of cardiovascular disease incidence: a systematic-review and dose-response meta-analysis of prospective cohort studies. Int. J. Behav. Nutr. Phys. Act. 21, 45. https:\/\/doi.org\/10.1186\/s12966-024-01593-8 (2024).","journal-title":"Int. J. Behav. Nutr. Phys. Act."},{"key":"85601_CR18","doi-asserted-by":"publisher","first-page":"e219","DOI":"10.1016\/S2468-2667(21)00302-9","volume":"7","author":"AE Paluch","year":"2022","unstructured":"Paluch, A. E. et al. Daily steps and all-cause mortality: a meta-analysis of 15 international cohorts. Lancet Public. Health. 7, e219\u2013e228. https:\/\/doi.org\/10.1016\/S2468-2667(21)00302-9 (2022).","journal-title":"Lancet Public. Health"},{"key":"85601_CR19","doi-asserted-by":"publisher","first-page":"674","DOI":"10.1016\/j.jshs.2024.01.010","volume":"13","author":"R Ross","year":"2024","unstructured":"Ross, R., Janssen, I. & Tremblay, M. S. Public health importance of light intensity physical activity. J. Sport Health Sci. 13, 674\u2013675. https:\/\/doi.org\/10.1016\/j.jshs.2024.01.010 (2024).","journal-title":"J. Sport Health Sci."},{"key":"85601_CR20","doi-asserted-by":"publisher","first-page":"e000775","DOI":"10.1136\/bmjsem-2020-000775","volume":"6","author":"JP Rey Lopez","year":"2020","unstructured":"Rey Lopez, J. P., Sabag, A., Martinez Juan, M., Rezende, L. F. M. & Pastor-Valero, M. Do vigorous-intensity and moderate-intensity physical activities reduce mortality to the same extent? A systematic review and meta-analysis. BMJ Open. Sport Exerc. Med. 6, e000775. https:\/\/doi.org\/10.1136\/bmjsem-2020-000775 (2020).","journal-title":"BMJ Open. Sport Exerc. Med."},{"key":"85601_CR21","doi-asserted-by":"publisher","first-page":"3726","DOI":"10.1177\/0962280217710835","volume":"27","author":"D Dumuid","year":"2018","unstructured":"Dumuid, D. et al. Compositional data analysis for physical activity, sedentary time and sleep research. Stat. Methods Med. Res. 27, 3726\u20133738. https:\/\/doi.org\/10.1177\/0962280217710835 (2018).","journal-title":"Stat. Methods Med. Res."},{"key":"85601_CR22","doi-asserted-by":"publisher","first-page":"519","DOI":"10.1093\/aje\/kwp163","volume":"170","author":"RA Mekary","year":"2009","unstructured":"Mekary, R. A., Willett, W. C., Hu, F. B. & Ding, E. L. Isotemporal substitution paradigm for physical activity epidemiology and weight change. Am. J. Epidemiol. 170, 519\u2013527. https:\/\/doi.org\/10.1093\/aje\/kwp163 (2009).","journal-title":"Am. J. Epidemiol."},{"key":"85601_CR23","doi-asserted-by":"publisher","first-page":"1571","DOI":"10.1016\/j.joca.2018.07.003","volume":"26","author":"RA Mekary","year":"2018","unstructured":"Mekary, R. A. Isotemporal substitution model for physical activity and osteoarthritis outcomes. Osteoarthr. Cartil. 26, 1571\u20131572. https:\/\/doi.org\/10.1016\/j.joca.2018.07.003 (2018).","journal-title":"Osteoarthr. Cartil."},{"key":"85601_CR24","doi-asserted-by":"publisher","first-page":"474","DOI":"10.1093\/aje\/kws590","volume":"178","author":"RA Mekary","year":"2013","unstructured":"Mekary, R. A. et al. Isotemporal substitution analysis for physical activity, television watching, and risk of depression. Am. J. Epidemiol. 178, 474\u2013483. https:\/\/doi.org\/10.1093\/aje\/kws590 (2013).","journal-title":"Am. J. Epidemiol."},{"key":"85601_CR25","doi-asserted-by":"publisher","first-page":"101424","DOI":"10.1016\/j.eclinm.2022.101424","volume":"48","author":"Z Cao","year":"2022","unstructured":"Cao, Z., Xu, C., Zhang, P. & Wang, Y. Associations of sedentary time and physical activity with adverse health conditions: outcome-wide analyses using isotemporal substitution model. EClinicalMedicine 48, 101424. https:\/\/doi.org\/10.1016\/j.eclinm.2022.101424 (2022).","journal-title":"EClinicalMedicine"},{"key":"85601_CR26","doi-asserted-by":"publisher","first-page":"e21367","DOI":"10.1097\/MD.0000000000021367","volume":"99","author":"Y Sun","year":"2020","unstructured":"Sun, Y. et al. Isotemporal substitution of sedentary behavior for physical activity on cardiorespiratory fitness in children and adolescents. Med. (Baltim). 99, e21367. https:\/\/doi.org\/10.1097\/MD.0000000000021367 (2020).","journal-title":"Med. (Baltim)."},{"key":"85601_CR27","doi-asserted-by":"publisher","first-page":"254","DOI":"10.1158\/1055-9965.EPI-16-0545","volume":"26","author":"T Boyle","year":"2017","unstructured":"Boyle, T., Vallance, J. K., Buman, M. P. & Lynch, B. M. Reallocating time to sleep, sedentary time, or physical activity: associations with waist circumference and body mass index in breast cancer survivors. Cancer Epidemiol. Biomarkers Prev. 26, 254\u2013260. https:\/\/doi.org\/10.1158\/1055-9965.EPI-16-0545 (2017).","journal-title":"Cancer Epidemiol. Biomarkers Prev."},{"key":"85601_CR28","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1016\/j.jsams.2023.04.007","volume":"26","author":"KP Sadarangani","year":"2023","unstructured":"Sadarangani, K. P. et al. Exchanging screen for non-screen sitting time or physical activity might attenuate depression and anxiety: a cross-sectional isotemporal analysis during early pandemics in South America. J. Sci. Med. Sport. 26, 309\u2013315. https:\/\/doi.org\/10.1016\/j.jsams.2023.04.007 (2023).","journal-title":"J. Sci. Med. Sport"},{"key":"85601_CR29","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1186\/s12877-023-03819-z","volume":"23","author":"TF Lai","year":"2023","unstructured":"Lai, T. F. et al. Effect of isotemporal substitution of sedentary behavior with different intensities of physical activity on the muscle function of older adults in the context of a medical center. BMC Geriatr. 23, 130. https:\/\/doi.org\/10.1186\/s12877-023-03819-z (2023).","journal-title":"BMC Geriatr."},{"key":"85601_CR30","doi-asserted-by":"publisher","unstructured":"Moura, B. P., Rufino, R. L., Faria, R. C., Sasaki, J. E. & Amorim, P. R. S. Can replacing sitting time with standing time improve adolescents\u2019 cardiometabolic health? Int. J. Environ. Res. Public. Health. 16 https:\/\/doi.org\/10.3390\/ijerph16173115 (2019).","DOI":"10.3390\/ijerph16173115"},{"key":"85601_CR31","doi-asserted-by":"publisher","first-page":"igad030","DOI":"10.1093\/geroni\/igad030","volume":"7","author":"N Feter","year":"2023","unstructured":"Feter, N. et al. Association between 24-hour movement behavior and cognitive function in Brazilian middle-aged and older adults: findings from the ELSA-Brasil. Innov. Aging. 7, igad030. https:\/\/doi.org\/10.1093\/geroni\/igad030 (2023).","journal-title":"Innov. Aging"},{"key":"85601_CR32","doi-asserted-by":"publisher","first-page":"1944","DOI":"10.1016\/j.apmr.2022.03.017","volume":"103","author":"A Freire","year":"2022","unstructured":"Freire, A. et al. Isotemporal substitution of sedentary behavior by different physical activity intensities on pain and disability of patients with chronic low back pain: a cross-sectional study. Arch. Phys. Med. Rehabil. 103, 1944\u20131950. https:\/\/doi.org\/10.1016\/j.apmr.2022.03.017 (2022).","journal-title":"Arch. Phys. Med. Rehabil"},{"key":"85601_CR33","doi-asserted-by":"publisher","first-page":"907","DOI":"10.1111\/sms.14323","volume":"33","author":"V Farrahi","year":"2023","unstructured":"Farrahi, V. et al. Replacing sedentary time with physical activity and sleep: associations with cardiometabolic health markers in adults. Scand. J. Med. Sci. Sports. 33, 907\u2013920. https:\/\/doi.org\/10.1111\/sms.14323 (2023).","journal-title":"Scand. J. Med. Sci. Sports"},{"key":"85601_CR34","doi-asserted-by":"publisher","first-page":"2683","DOI":"10.1111\/liv.15439","volume":"42","author":"J Wang","year":"2022","unstructured":"Wang, J. et al. Isotemporal substitution of different behaviour patterns with the presence of MAFLD in Chinese adults. Liver Int. 42, 2683\u20132695. https:\/\/doi.org\/10.1111\/liv.15439 (2022).","journal-title":"Liver Int."},{"key":"85601_CR35","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1016\/j.maturitas.2018.02.003","volume":"110","author":"D Dumuid","year":"2018","unstructured":"Dumuid, D. et al. Relationships between older adults\u2019 use of time and cardio-respiratory fitness, obesity and cardio-metabolic risk: a compositional isotemporal substitution analysis. Maturitas 110, 104\u2013110. https:\/\/doi.org\/10.1016\/j.maturitas.2018.02.003 (2018).","journal-title":"Maturitas"},{"key":"85601_CR36","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1186\/s12966-020-00936-5","volume":"17","author":"N Swindell","year":"2020","unstructured":"Swindell, N. et al. Compositional analysis of the associations between 24-h movement behaviours and cardio-metabolic risk factors in overweight and obese adults with pre-diabetes from the PREVIEW study: cross-sectional baseline analysis. Int. J. Behav. Nutr. Phys. Act. 17, 29. https:\/\/doi.org\/10.1186\/s12966-020-00936-5 (2020).","journal-title":"Int. J. Behav. Nutr. Phys. Act."},{"key":"85601_CR37","doi-asserted-by":"publisher","first-page":"1114","DOI":"10.1123\/jpah.2024-0149","volume":"21","author":"LA Volpato","year":"2024","unstructured":"Volpato, L. A. et al. Associations between substitution of sedentary behavior patterns with physical activity and cardiovascular risk factors in adolescents: a 3-year longitudinal study. J. Phys. Act. Health. 21, 1114\u20131120. https:\/\/doi.org\/10.1123\/jpah.2024-0149 (2024).","journal-title":"J. Phys. Act. Health"},{"key":"85601_CR38","doi-asserted-by":"publisher","first-page":"e0266926","DOI":"10.1371\/journal.pone.0266926","volume":"17","author":"SF Domingues","year":"2022","unstructured":"Domingues, S. F., Diniz da Silva, C., Faria, F. R., de Sa Souza, H. & Dos Santos Amorim, P. R. Sleep, sedentary behavior, and physical activity in Brazilian adolescents: achievement recommendations and BMI associations through compositional data analysis. PLoS One. 17, e0266926. https:\/\/doi.org\/10.1371\/journal.pone.0266926 (2022).","journal-title":"PLoS One"},{"key":"85601_CR39","doi-asserted-by":"publisher","first-page":"e0225856","DOI":"10.1371\/journal.pone.0225856","volume":"14","author":"BP Moura","year":"2019","unstructured":"Moura, B. P., Rufino, R. L., Faria, R. C. & Amorim, P. R. S. Effects of isotemporal substitution of sedentary behavior with light-intensity or moderate-to-vigorous physical activity on cardiometabolic markers in male adolescents. PLoS One. 14, e0225856. https:\/\/doi.org\/10.1371\/journal.pone.0225856 (2019).","journal-title":"PLoS One"},{"key":"85601_CR40","doi-asserted-by":"publisher","unstructured":"Gonze, B. B. et al. Effects of substituting sedentary behavior with light-intensity or moderate-to-vigorous physical activity on obesity indices in adults: a prospective short-term follow-up study. Int. J. Environ. Res. Public. Health. 18 https:\/\/doi.org\/10.3390\/ijerph182413335 (2021).","DOI":"10.3390\/ijerph182413335"},{"key":"85601_CR41","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1079\/phn2001301","volume":"5","author":"V Matsudo","year":"2002","unstructured":"Matsudo, V. et al. Promotion of physical activity in a developing country: the Agita Sao Paulo experience. Public. Health Nutr. 5, 253\u2013261. https:\/\/doi.org\/10.1079\/phn2001301 (2002).","journal-title":"Public. Health Nutr."},{"key":"85601_CR42","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1590\/s1020-49892003000900007","volume":"14","author":"SM Matsudo","year":"2003","unstructured":"Matsudo, S. M. et al. The Agita Sao Paulo Program as a model for using physical activity to promote health. Rev. Panam. Salud Publica. 14, 265\u2013272. https:\/\/doi.org\/10.1590\/s1020-49892003000900007 (2003).","journal-title":"Rev. Panam. Salud Publica"},{"key":"85601_CR43","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1016\/j.healthplace.2011.09.011","volume":"18","author":"V Matsudo","year":"2012","unstructured":"Matsudo, V. The role of partnerships in promoting physical activity: the experience of Agita Sao Paulo. Health Place. 18, 121\u2013122. https:\/\/doi.org\/10.1016\/j.healthplace.2011.09.011 (2012).","journal-title":"Health Place"},{"key":"85601_CR44","doi-asserted-by":"publisher","first-page":"1095","DOI":"10.1590\/1413-81232015214.19792015","volume":"21","author":"LJ Silva","year":"2016","unstructured":"Silva, L. J. et al. The prevalence of physical activity and its associated effects among students in the Sao Paulo public school network, Brazil. Cien Saude Colet. 21, 1095\u20131103. https:\/\/doi.org\/10.1590\/1413-81232015214.19792015 (2016).","journal-title":"Cien Saude Colet"},{"key":"85601_CR45","doi-asserted-by":"publisher","first-page":"1381","DOI":"10.1249\/01.MSS.0000078924.61453.FB","volume":"35","author":"CL Craig","year":"2003","unstructured":"Craig, C. L. et al. International physical activity questionnaire: 12-country reliability and validity. Med. Sci. Sports Exerc. 35, 1381\u20131395. https:\/\/doi.org\/10.1249\/01.MSS.0000078924.61453.FB (2003).","journal-title":"Med. Sci. Sports Exerc."},{"key":"85601_CR46","doi-asserted-by":"publisher","first-page":"5","DOI":"10.12820\/rbafs.v.6n2p5-18","volume":"6","author":"S Matsudo","year":"2012","unstructured":"Matsudo, S. et al. QUESTION\u00c1RIO INTERNACIONAL DE ATIVIDADE F\u00cdSICA (IPAQ): ESTUDO DE VALIDADE E REPRODUTIBILIDADE NO BRASIL. Revista Brasileira De Atividade F\u00edsica Sa\u00fade 6, 5\u201318. doi:https:\/\/doi.org\/10.12820\/rbafs.v.6n2p5-18 (2012).","journal-title":"Revista Brasileira De Atividade F\u00edsica Sa\u00fade"},{"key":"85601_CR47","doi-asserted-by":"publisher","first-page":"2241","DOI":"10.1186\/s12889-023-17134-0","volume":"23","author":"Y Liu","year":"2023","unstructured":"Liu, Y., Lin, H., Zhang, H., Zhang, X. & Yin, S. Correlation analysis between physical activity and depressive tendencies among occupational groups: an isotemporal substitution approach. BMC Public. Health. 23, 2241. https:\/\/doi.org\/10.1186\/s12889-023-17134-0 (2023).","journal-title":"BMC Public. Health"},{"key":"85601_CR48","unstructured":"COMMITTEE I R. Guidelines for the Data Processing and Analysis of the International Physical Activity Questionnaire [EB\/OL]. (2005). https:\/\/sites.google.com\/site\/theipaq. Accessed December 2024."},{"key":"85601_CR49","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1186\/s12966-018-0691-3","volume":"15","author":"J Grgic","year":"2018","unstructured":"Grgic, J. et al. Health outcomes associated with reallocations of time between sleep, sedentary behaviour, and physical activity: a systematic scoping review of isotemporal substitution studies. Int. J. Behav. Nutr. Phys. Act. 15, 69. https:\/\/doi.org\/10.1186\/s12966-018-0691-3 (2018).","journal-title":"Int. J. Behav. Nutr. Phys. Act."},{"key":"85601_CR50","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1186\/s12966-019-0892-4","volume":"16","author":"AM Galmes-Panades","year":"2019","unstructured":"Galmes-Panades, A. M. et al. Isotemporal substitution of inactive time with physical activity and time in bed: cross-sectional associations with cardiometabolic health in the PREDIMED-Plus study. Int. J. Behav. Nutr. Phys. Act. 16, 137. https:\/\/doi.org\/10.1186\/s12966-019-0892-4 (2019).","journal-title":"Int. J. Behav. Nutr. Phys. Act."},{"key":"85601_CR51","doi-asserted-by":"publisher","first-page":"859","DOI":"10.1017\/S0007114508925460","volume":"100","author":"NE Jensky-Squires","year":"2008","unstructured":"Jensky-Squires, N. E. et al. Validity and reliability of body composition analysers in children and adults. Br. J. Nutr. 100, 859\u2013865. https:\/\/doi.org\/10.1017\/S0007114508925460 (2008).","journal-title":"Br. J. Nutr."},{"key":"85601_CR52","unstructured":"Pesquisa, A. B. d. E. d. & Pesquisa, A. B. d. E. d. Crit\u00e9rio de classifica\u00e7\u00e3o econ\u00f4mica Brasil. (2014). http:\/\/www.abep.org\/criterio-brasil Accessed April 2024."},{"key":"85601_CR53","doi-asserted-by":"publisher","first-page":"100593","DOI":"10.1016\/j.jth.2019.100593","volume":"14","author":"KP Sadarangani","year":"2019","unstructured":"Sadarangani, K. P. et al. Substituting sedentary time with physical activity domains: an isotemporal substitution analysis in Chile. J. Transp. Health. 14, 100593. https:\/\/doi.org\/10.1016\/j.jth.2019.100593 (2019).","journal-title":"J. Transp. Health"},{"key":"85601_CR54","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1186\/s12966-015-0280-7","volume":"12","author":"E Stamatakis","year":"2015","unstructured":"Stamatakis, E. et al. All-cause mortality effects of replacing sedentary time with physical activity and sleeping using an isotemporal substitution model: a prospective study of 201,129 mid-aged and older adults. Int. J. Behav. Nutr. Phys. Act. 12, 121. https:\/\/doi.org\/10.1186\/s12966-015-0280-7 (2015).","journal-title":"Int. J. Behav. Nutr. Phys. Act."},{"key":"85601_CR55","doi-asserted-by":"publisher","first-page":"1705","DOI":"10.1111\/sms.13726","volume":"30","author":"BH Hansen","year":"2020","unstructured":"Hansen, B. H. et al. Step by step: Association of device-measured daily steps with all-cause mortality-A prospective cohort study. Scand. J. Med. Sci. Sports. 30, 1705\u20131711. https:\/\/doi.org\/10.1111\/sms.13726 (2020).","journal-title":"Scand. J. Med. Sci. Sports"},{"key":"85601_CR56","doi-asserted-by":"publisher","first-page":"370","DOI":"10.1136\/bjsports-2017-097563","volume":"53","author":"SFM Chastin","year":"2019","unstructured":"Chastin, S. F. M. et al. How does light-intensity physical activity associate with adult cardiometabolic health and mortality? Systematic review with meta-analysis of experimental and observational studies. Br. J. Sports Med. 53, 370\u2013376. https:\/\/doi.org\/10.1136\/bjsports-2017-097563 (2019).","journal-title":"Br. J. Sports Med."},{"key":"85601_CR57","doi-asserted-by":"publisher","first-page":"105737","DOI":"10.1016\/j.jsbmb.2020.105737","volume":"203","author":"D Dhawan","year":"2020","unstructured":"Dhawan, D. & Sharma, S. Abdominal obesity, adipokines and non-communicable diseases. J. Steroid Biochem. Mol. Biol. 203, 105737. https:\/\/doi.org\/10.1016\/j.jsbmb.2020.105737 (2020).","journal-title":"J. Steroid Biochem. Mol. Biol."},{"key":"85601_CR58","doi-asserted-by":"publisher","first-page":"1573","DOI":"10.1038\/s41366-022-01165-5","volume":"46","author":"A Jayedi","year":"2022","unstructured":"Jayedi, A., Khan, T. A., Aune, D., Emadi, A. & Shab-Bidar, S. Body fat and risk of all-cause mortality: a systematic review and dose-response meta-analysis of prospective cohort studies. Int. J. Obes. (Lond). 46, 1573\u20131581. https:\/\/doi.org\/10.1038\/s41366-022-01165-5 (2022).","journal-title":"Int. J. Obes. (Lond)"},{"key":"85601_CR59","doi-asserted-by":"publisher","first-page":"641","DOI":"10.2165\/11590680-000000000-00000","volume":"41","author":"P Ekkekakis","year":"2011","unstructured":"Ekkekakis, P., Parfitt, G. & Petruzzello, S. J. The pleasure and displeasure people feel when they exercise at different intensities. Sports Med. 41, 641\u2013671. https:\/\/doi.org\/10.2165\/11590680-000000000-00000 (2011).","journal-title":"Sports Med."},{"key":"85601_CR60","doi-asserted-by":"publisher","unstructured":"Niedermeier, M., Ledochowski, L., Leitner, H., Zingerle, H. & Kopp, M. Acute effects of a single bout of walking on affective responses in patients with major depressive disorder. Int. J. Environ. Res. Public. Health. 18 https:\/\/doi.org\/10.3390\/ijerph18041524 (2021).","DOI":"10.3390\/ijerph18041524"},{"key":"85601_CR61","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1186\/s12966-018-0695-z","volume":"15","author":"S Amagasa","year":"2018","unstructured":"Amagasa, S. et al. Is objectively measured light-intensity physical activity associated with health outcomes after adjustment for moderate-to-vigorous physical activity in adults? A systematic review. Int. J. Behav. Nutr. Phys. Act. 15, 65. https:\/\/doi.org\/10.1186\/s12966-018-0695-z (2018).","journal-title":"Int. J. Behav. Nutr. Phys. Act."},{"key":"85601_CR62","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1186\/s13098-023-01040-x","volume":"15","author":"PJ Collings","year":"2023","unstructured":"Collings, P. J. et al. Substituting device-measured sedentary time with alternative 24-hour movement behaviours: compositional associations with adiposity and cardiometabolic risk in the ORISCAV-LUX 2 study. Diabetol. Metab. Syndr. 15, 70. https:\/\/doi.org\/10.1186\/s13098-023-01040-x (2023).","journal-title":"Diabetol. Metab. Syndr."},{"key":"85601_CR63","doi-asserted-by":"publisher","first-page":"8657","DOI":"10.1038\/s41598-018-26616-w","volume":"8","author":"B Duvivier","year":"2018","unstructured":"Duvivier, B. et al. Reducing sitting time versus adding exercise: differential effects on biomarkers of endothelial dysfunction and metabolic risk. Sci. Rep. 8, 8657. https:\/\/doi.org\/10.1038\/s41598-018-26616-w (2018).","journal-title":"Sci. Rep."},{"key":"85601_CR64","doi-asserted-by":"publisher","first-page":"1041622","DOI":"10.3389\/fphys.2023.1041622","volume":"14","author":"Y Cao","year":"2023","unstructured":"Cao, Y. et al. The effect of different intensity physical activity on cardiovascular metabolic health in obese children and adolescents: an isotemporal substitution model. Front. Physiol. 14, 1041622. https:\/\/doi.org\/10.3389\/fphys.2023.1041622 (2023).","journal-title":"Front. Physiol."},{"key":"85601_CR65","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1186\/s12916-020-01847-9","volume":"19","author":"AM Galmes-Panades","year":"2021","unstructured":"Galmes-Panades, A. M. et al. Targeting body composition in an older population: do changes in movement behaviours matter? Longitudinal analyses in the PREDIMED-Plus trial. BMC Med. 19, 3. https:\/\/doi.org\/10.1186\/s12916-020-01847-9 (2021).","journal-title":"BMC Med."},{"key":"85601_CR66","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1002\/oby.23631","volume":"31","author":"SC Larsen","year":"2023","unstructured":"Larsen, S. C. et al. Substituting sedentary time with sleep or physical activity and subsequent weight-loss maintenance. Obes. (Silver Spring). 31, 515\u2013524. https:\/\/doi.org\/10.1002\/oby.23631 (2023).","journal-title":"Obes. (Silver Spring)"},{"key":"85601_CR67","doi-asserted-by":"publisher","first-page":"837213","DOI":"10.3389\/fpubh.2022.837213","volume":"10","author":"TF Lai","year":"2022","unstructured":"Lai, T. F. et al. Substituting sedentary time with physical activity in youngest-old to oldest-old community-dwelling older adults: associations with body composition. Front. Public. Health. 10, 837213. https:\/\/doi.org\/10.3389\/fpubh.2022.837213 (2022).","journal-title":"Front. Public. Health"},{"key":"85601_CR68","doi-asserted-by":"publisher","first-page":"e0232420","DOI":"10.1371\/journal.pone.0232420","volume":"15","author":"GL Ferrari","year":"2020","unstructured":"Ferrari, G. L. et al. Comparison of self-report versus accelerometer \u2013 measured physical activity and sedentary behaviors and their association with body composition in latin American countries. PLOS ONE. 15, e0232420. https:\/\/doi.org\/10.1371\/journal.pone.0232420 (2020).","journal-title":"PLOS ONE"},{"key":"85601_CR69","doi-asserted-by":"publisher","first-page":"3","DOI":"10.25318\/82-003-x201900700001-eng","volume":"30","author":"RC Colley","year":"2019","unstructured":"Colley, R. C., Butler, G., Garriguet, D., Prince, S. A. & Roberts, K. C. Comparison of self-reported and accelerometer-measured physical activity among Canadian youth. Health Rep. 30, 3\u201312. https:\/\/doi.org\/10.25318\/82-003-x201900700001-eng (2019).","journal-title":"Health Rep."},{"key":"85601_CR70","doi-asserted-by":"publisher","first-page":"648","DOI":"10.4103\/ijmr.IJMR_1777_18","volume":"148","author":"R Kuriyan","year":"2018","unstructured":"Kuriyan, R. Body composition techniques. Indian J. Med. Res. 148, 648\u2013658. https:\/\/doi.org\/10.4103\/ijmr.IJMR_1777_18 (2018).","journal-title":"Indian J. Med. Res."},{"key":"85601_CR71","doi-asserted-by":"publisher","first-page":"846","DOI":"10.1177\/0962280217737805","volume":"28","author":"D Dumuid","year":"2019","unstructured":"Dumuid, D. et al. The compositional isotemporal substitution model: a method for estimating changes in a health outcome for reallocation of time between sleep, physical activity and sedentary behaviour. Stat. Methods Med. Res. 28, 846\u2013857. https:\/\/doi.org\/10.1177\/0962280217737805 (2019).","journal-title":"Stat. Methods Med. Res."},{"key":"85601_CR72","doi-asserted-by":"publisher","first-page":"185e181","DOI":"10.1016\/j.jamda.2017.11.003","volume":"19","author":"A Manas","year":"2018","unstructured":"Manas, A. et al. Reallocating accelerometer-assessed sedentary time to light or moderate- to vigorous-intensity physical activity reduces frailty levels in older adults: an isotemporal substitution approach in the TSHA study. J. Am. Med. Dir. Assoc. 19, 185e181\u2013185e186. https:\/\/doi.org\/10.1016\/j.jamda.2017.11.003 (2018).","journal-title":"J. Am. Med. Dir. Assoc."},{"key":"85601_CR73","doi-asserted-by":"publisher","first-page":"e2416300","DOI":"10.1001\/jamanetworkopen.2024.16300","volume":"7","author":"H Shi","year":"2024","unstructured":"Shi, H. et al. Sedentary behaviors, light-intensity physical activity, and healthy aging. JAMA Netw. Open. 7, e2416300. https:\/\/doi.org\/10.1001\/jamanetworkopen.2024.16300 (2024).","journal-title":"JAMA Netw. Open."},{"key":"85601_CR74","doi-asserted-by":"publisher","unstructured":"Biskup, M. et al. Agreement between accelerometer-assessed and self-reported physical activity and sedentary behavior in female breast cancer survivors. Diagnostics (Basel). 13. https:\/\/doi.org\/10.3390\/diagnostics13223447 (2023).","DOI":"10.3390\/diagnostics13223447"},{"key":"85601_CR75","doi-asserted-by":"publisher","unstructured":"Marra, M. et al. Assessment of body composition in health and disease using bioelectrical impedance analysis (BIA) and dual energy x-ray absorptiometry (DXA): a critical overview. Contrast Media Mol Imaging. 2019, 3548284. https:\/\/doi.org\/10.1155\/2019\/3548284 (2019).","DOI":"10.1155\/2019\/3548284"},{"key":"85601_CR76","doi-asserted-by":"publisher","first-page":"390","DOI":"10.1111\/jhn.12257","volume":"28","author":"A Gaba","year":"2015","unstructured":"Gaba, A., Kapus, O., Cuberek, R. & Botek, M. Comparison of multi- and single-frequency bioelectrical impedance analysis with dual-energy X-ray absorptiometry for assessment of body composition in post-menopausal women: effects of body mass index and accelerometer-determined physical activity. J. Hum. Nutr. Diet. 28, 390\u2013400. https:\/\/doi.org\/10.1111\/jhn.12257 (2015).","journal-title":"J. Hum. Nutr. Diet."}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-85601-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-85601-2","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-85601-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,11]],"date-time":"2025-01-11T07:02:27Z","timestamp":1736578947000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-85601-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,11]]},"references-count":76,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["85601"],"URL":"https:\/\/doi.org\/10.1038\/s41598-025-85601-2","relation":{},"ISSN":["2045-2322"],"issn-type":[{"value":"2045-2322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,11]]},"assertion":[{"value":"3 September 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 January 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 January 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"1684"}}