{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T17:14:27Z","timestamp":1793812467228,"version":"4.6.1"},"reference-count":48,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,1,8]],"date-time":"2025-01-08T00:00:00Z","timestamp":1736294400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,1,8]],"date-time":"2025-01-08T00:00:00Z","timestamp":1736294400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"name":"the Natural Science Foundation of Liaoning Province","award":["2023-MS-07"],"award-info":[{"award-number":["2023-MS-07"]}]},{"name":"the Doctoral Fund of Liaoning Province","award":["2022-BS-141"],"award-info":[{"award-number":["2022-BS-141"]}]},{"name":"the Chinese National Key Technology R&D Program","award":["2021YFC2501303"],"award-info":[{"award-number":["2021YFC2501303"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"DOI":"10.1038\/s41598-025-85648-1","type":"journal-article","created":{"date-parts":[[2025,1,8]],"date-time":"2025-01-08T06:42:32Z","timestamp":1736318552000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Alterations in cerebral perfusion and corresponding brain functional networks in systemic lupus erythematosus with cognitive impairment"],"prefix":"10.1038","volume":"15","author":[{"given":"Huiyang","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hu","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bailing","family":"Tian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pingting","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guoguang","family":"Fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,1,8]]},"reference":[{"key":"85648_CR1","doi-asserted-by":"publisher","first-page":"496","DOI":"10.1212\/wnl.57.3.496","volume":"57","author":"H Ainiala","year":"2001","unstructured":"Ainiala, H., Loukkola, J., Peltola, J., Korpela, M. & Hietaharju, A. The prevalence of neuropsychiatric syndromes in systemic lupus erythematosus. Neurology 57, 496\u2013500. https:\/\/doi.org\/10.1212\/wnl.57.3.496 (2001).","journal-title":"Neurology"},{"key":"85648_CR2","doi-asserted-by":"publisher","first-page":"240","DOI":"10.1016\/j.semarthrit.2018.02.007","volume":"48","author":"HA Rayes","year":"2018","unstructured":"Rayes, H. A. et al. What is the prevalence of cognitive impairment in lupus and which instruments are used to measure it? A systematic review and meta-analysis. Semin Arthritis Rheum. 48, 240\u2013255. https:\/\/doi.org\/10.1016\/j.semarthrit.2018.02.007 (2018).","journal-title":"Semin Arthritis Rheum."},{"key":"85648_CR3","doi-asserted-by":"publisher","unstructured":"Raghunath, S., Glikmann-Johnston, Y., Morand, E., Stout, J. C. & Hoi, A. Evaluation of the Montreal cognitive assessment as a screening tool for cognitive dysfunction in SLE. Lupus Sci. Med. 8 https:\/\/doi.org\/10.1136\/lupus-2021-000580 (2021).","DOI":"10.1136\/lupus-2021-000580"},{"key":"85648_CR4","doi-asserted-by":"publisher","unstructured":"Langensee, L. et al. Cognitive performance in systemic lupus erythematosus patients: A cross-sectional and longitudinal study. BMC Rheumatol. 6 https:\/\/doi.org\/10.1186\/s41927-022-00253-3 (2022).","DOI":"10.1186\/s41927-022-00253-3"},{"key":"85648_CR5","doi-asserted-by":"publisher","first-page":"212","DOI":"10.1148\/rg.210045","volume":"42","author":"Y Ota","year":"2022","unstructured":"Ota, Y. et al. Central nervous system systemic lupus erythematosus: Pathophysiologic, clinical, and imaging features. Radiographics 42, 212\u2013232. https:\/\/doi.org\/10.1148\/rg.210045 (2022).","journal-title":"Radiographics"},{"key":"85648_CR6","doi-asserted-by":"publisher","first-page":"102637","DOI":"10.1016\/j.nicl.2021.102637","volume":"30","author":"M Bulk","year":"2021","unstructured":"Bulk, M. et al. Quantitative susceptibility mapping in the thalamus and basal ganglia of systemic lupus erythematosus patients with neuropsychiatric complaints. Neuroimage Clin. 30, 102637. https:\/\/doi.org\/10.1016\/j.nicl.2021.102637 (2021).","journal-title":"Neuroimage Clin."},{"key":"85648_CR7","doi-asserted-by":"publisher","first-page":"577518","DOI":"10.1016\/j.jneuroim.2021.577518","volume":"353","author":"B Thirunavukkarasu","year":"2021","unstructured":"Thirunavukkarasu, B. et al. Neuropathological spectrum in systemic lupus erythematosus: A single institute autopsy experience. J. Neuroimmunol. 353, 577518. https:\/\/doi.org\/10.1016\/j.jneuroim.2021.577518 (2021).","journal-title":"J. Neuroimmunol."},{"key":"85648_CR8","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1136\/annrheumdis-2017-212285","volume":"77","author":"E Papadaki","year":"2018","unstructured":"Papadaki, E. et al. Neuropsychiatric lupus or not? Cerebral hypoperfusion by perfusion-weighted MRI in normal-appearing white matter in primary neuropsychiatric lupus erythematosus. Ann. Rheum. Dis. 77, 441\u2013448. https:\/\/doi.org\/10.1136\/annrheumdis-2017-212285 (2018).","journal-title":"Ann. Rheum. Dis."},{"key":"85648_CR9","doi-asserted-by":"publisher","first-page":"e000327","DOI":"10.1136\/lupus-2019-000327","volume":"6","author":"E Ploran","year":"2019","unstructured":"Ploran, E. et al. Assessing cognitive impairment in SLE: Examining relationships between resting glucose metabolism and anti-NMDAR antibodies with navigational performance. Lupus Sci. Med. 6, e000327. https:\/\/doi.org\/10.1136\/lupus-2019-000327 (2019).","journal-title":"Lupus Sci. Med."},{"key":"85648_CR10","doi-asserted-by":"publisher","unstructured":"Mackay, M. et al. Metabolic and microstructural alterations in the SLE brain correlate with cognitive impairment. JCI Insight. 4 https:\/\/doi.org\/10.1172\/jci.insight.124002 (2019).","DOI":"10.1172\/jci.insight.124002"},{"key":"85648_CR11","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1177\/0961203316657432","volume":"26","author":"Y Wang","year":"2017","unstructured":"Wang, Y. et al. Neuroimaging of translocator protein in patients with systemic lupus erythematosus: A pilot study using [(11)C]DPA-713 positron emission tomography. Lupus 26, 170\u2013178. https:\/\/doi.org\/10.1177\/0961203316657432 (2017).","journal-title":"Lupus"},{"key":"85648_CR12","doi-asserted-by":"publisher","unstructured":"Salomonsson, T. et al. Abnormal cerebral hemodynamics and blood-brain barrier permeability detected with perfusion MRI in systemic lupus erythematosus patients. NeuroImage Clin. 38 https:\/\/doi.org\/10.1016\/j.nicl.2023.103390 (2023).","DOI":"10.1016\/j.nicl.2023.103390"},{"key":"85648_CR13","doi-asserted-by":"publisher","first-page":"1580","DOI":"10.1136\/annrheumdis-2020-218004","volume":"79","author":"L Kamintsky","year":"2020","unstructured":"Kamintsky, L. et al. Blood-brain barrier leakage in systemic lupus erythematosus is associated with gray matter loss and cognitive impairment. Ann. Rheum. Dis. 79, 1580\u20131587. https:\/\/doi.org\/10.1136\/annrheumdis-2020-218004 (2020).","journal-title":"Ann. Rheum. Dis."},{"key":"85648_CR14","doi-asserted-by":"publisher","first-page":"346","DOI":"10.1016\/j.nurt.2007.04.005","volume":"4","author":"RL Wolf","year":"2007","unstructured":"Wolf, R. L. & Detre, J. A. Clinical neuroimaging using arterial spin-labeled perfusion magnetic resonance imaging. Neurotherapeutics 4, 346\u2013359 (2007).","journal-title":"Neurotherapeutics"},{"key":"85648_CR15","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1016\/j.jalz.2011.06.003","volume":"8","author":"ES Musiek","year":"2012","unstructured":"Musiek, E. S. et al. Direct comparison of fluorodeoxyglucose positron emission tomography and arterial spin labeling magnetic resonance imaging in Alzheimer\u2019s disease. Alzheimers Dement. 8, 51\u201359. https:\/\/doi.org\/10.1016\/j.jalz.2011.06.003 (2012).","journal-title":"Alzheimers Dement."},{"key":"85648_CR16","doi-asserted-by":"publisher","first-page":"117246","DOI":"10.1016\/j.neuroimage.2020.117246","volume":"223","author":"JG Woods","year":"2020","unstructured":"Woods, J. G., Chappell, M. A. & Okell, T. W. Designing and comparing optimized pseudo-continuous arterial spin labeling protocols for measurement of cerebral blood flow. Neuroimage 223, 117246. https:\/\/doi.org\/10.1016\/j.neuroimage.2020.117246 (2020).","journal-title":"Neuroimage"},{"key":"85648_CR17","doi-asserted-by":"publisher","first-page":"755","DOI":"10.1002\/hbm.24837","volume":"41","author":"Z Zhuo","year":"2020","unstructured":"Zhuo, Z. et al. Different patterns of cerebral perfusion in SLE patients with and without neuropsychiatric manifestations. Hum. Brain Mapp. 41, 755\u2013766. https:\/\/doi.org\/10.1002\/hbm.24837 (2020).","journal-title":"Hum. Brain Mapp."},{"key":"85648_CR18","doi-asserted-by":"publisher","first-page":"1128","DOI":"10.1177\/0961203319861677","volume":"28","author":"J Jia","year":"2019","unstructured":"Jia, J. et al. Cerebral blood flow abnormalities in neuropsychiatric systemic lupus erythematosus. Lupus 28, 1128\u20131133. https:\/\/doi.org\/10.1177\/0961203319861677 (2019).","journal-title":"Lupus"},{"key":"85648_CR19","first-page":"60","volume":"29","author":"L Wang","year":"2023","unstructured":"Wang, L., Zheng, G., Jia, X., Zhang, X. & Chen, Y. Application study of brain structure and functional magnetic resonance imaging in patients with systemic lupus erythematosus and cognitive dysfunction. Altern. Ther. Health Med. 29, 60\u201365 (2023).","journal-title":"Altern. Ther. Health Med."},{"key":"85648_CR20","doi-asserted-by":"publisher","first-page":"685","DOI":"10.1093\/rheumatology\/keac343","volume":"62","author":"JG Hanly","year":"2023","unstructured":"Hanly, J. G. et al. Resting state functional connectivity in SLE patients and association with cognitive impairment and blood-brain barrier permeability. Rheumatol. (Oxford). 62, 685\u2013695. https:\/\/doi.org\/10.1093\/rheumatology\/keac343 (2023).","journal-title":"Rheumatol. (Oxford)"},{"key":"85648_CR21","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1016\/j.neuroimage.2014.11.028","volume":"106","author":"K Jann","year":"2015","unstructured":"Jann, K. et al. Functional connectivity in BOLD and CBF data: Similarity and reliability of resting brain networks. Neuroimage 106, 111\u2013122. https:\/\/doi.org\/10.1016\/j.neuroimage.2014.11.028 (2015).","journal-title":"Neuroimage"},{"key":"85648_CR22","doi-asserted-by":"publisher","first-page":"1725","DOI":"10.1002\/art.1780400928","volume":"40","author":"MC Hochberg","year":"1997","unstructured":"Hochberg, M. C. Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum. 40, 1725 (1997).","journal-title":"Arthritis Rheum."},{"key":"85648_CR23","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1046\/j.1365-2133.2000.03356.x","volume":"142","author":"A Parodi","year":"2000","unstructured":"Parodi, A. et al. Measuring the activity of the disease in patients with cutaneous lupus erythematosus. Br. J. Dermatol. 142, 457\u2013460 (2000).","journal-title":"Br. J. Dermatol."},{"key":"85648_CR24","doi-asserted-by":"publisher","first-page":"2663","DOI":"10.1093\/rheumatology\/keab823","volume":"61","author":"F Inglese","year":"2022","unstructured":"Inglese, F. et al. Neuropsychiatric systemic lupus erythematosus is associated with a distinct type and shape of cerebral white matter hyperintensities. Rheumatol. (Oxford). 61, 2663\u20132671. https:\/\/doi.org\/10.1093\/rheumatology\/keab823 (2022).","journal-title":"Rheumatol. (Oxford)"},{"key":"85648_CR25","doi-asserted-by":"publisher","first-page":"276","DOI":"10.1016\/j.neurad.2018.06.003","volume":"45","author":"ML Ho","year":"2018","unstructured":"Ho, M. L. Arterial spin labeling: Clinical applications. J. Neuroradiol. 45, 276\u2013289. https:\/\/doi.org\/10.1016\/j.neurad.2018.06.003 (2018).","journal-title":"J. Neuroradiol."},{"key":"85648_CR26","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1093\/rheumatology\/kew341","volume":"56","author":"D Cohen","year":"2017","unstructured":"Cohen, D. et al. Brain histopathology in patients with systemic lupus erythematosus: Identification of lesions associated with clinical neuropsychiatric lupus syndromes and the role of complement. Rheumatol. (Oxford). 56, 77\u201386. https:\/\/doi.org\/10.1093\/rheumatology\/kew341 (2017).","journal-title":"Rheumatol. (Oxford)"},{"key":"85648_CR27","doi-asserted-by":"publisher","first-page":"426","DOI":"10.1016\/j.autrev.2018.12.004","volume":"18","author":"NP Duarte-Delgado","year":"2019","unstructured":"Duarte-Delgado, N. P., V\u00e1squez, G. & Ortiz-Reyes, B. L. Blood-brain barrier disruption and neuroinflammation as pathophysiological mechanisms of the diffuse manifestations of neuropsychiatric systemic lupus erythematosus. Autoimmun. Rev. 18, 426\u2013432. https:\/\/doi.org\/10.1016\/j.autrev.2018.12.004 (2019).","journal-title":"Autoimmun. rev."},{"key":"85648_CR28","doi-asserted-by":"publisher","first-page":"470","DOI":"10.3174\/ajnr.A5990","volume":"40","author":"JM Chi","year":"2019","unstructured":"Chi, J. M. et al. Alterations in blood-brain barrier permeability in patients with systemic lupus erythematosus. AJNR Am. J. Neuroradiol. 40, 470\u2013477. https:\/\/doi.org\/10.3174\/ajnr.A5990 (2019).","journal-title":"AJNR Am. J. Neuroradiol."},{"key":"85648_CR29","doi-asserted-by":"publisher","unstructured":"Liu, S. et al. Hippocampal atrophy in systemic lupus erythematosus patients without major neuropsychiatric manifestations. J. Immunol. Res. 2020 (2943848). https:\/\/doi.org\/10.1155\/2020\/2943848 (2020).","DOI":"10.1155\/2020\/2943848"},{"key":"85648_CR30","doi-asserted-by":"publisher","first-page":"e33","DOI":"10.1111\/epi.12012","volume":"54","author":"T Toyota","year":"2013","unstructured":"Toyota, T. et al. Mesial temporal lobe epilepsy as a neuropsychiatric syndrome of systemic lupus erythematosus. Epilepsia 54, e33\u201336. https:\/\/doi.org\/10.1111\/epi.12012 (2013).","journal-title":"Epilepsia"},{"key":"85648_CR31","doi-asserted-by":"publisher","first-page":"204","DOI":"10.1002\/art.38900","volume":"67","author":"M Bravo-Zehnder","year":"2015","unstructured":"Bravo-Zehnder, M. et al. Anti-ribosomal P protein autoantibodies from patients with neuropsychiatric lupus impair memory in mice. Arthritis Rheumatol. 67, 204\u2013214. https:\/\/doi.org\/10.1002\/art.38900 (2015).","journal-title":"Arthritis Rheumatol."},{"key":"85648_CR32","doi-asserted-by":"publisher","first-page":"1598","DOI":"10.1002\/art.39081","volume":"67","author":"F Segovia-Miranda","year":"2015","unstructured":"Segovia-Miranda, F. et al. Pathogenicity of lupus anti-ribosomal P antibodies: Role of cross-reacting neuronal surface P antigen in glutamatergic transmission and plasticity in a mouse model. Arthritis Rheumatol. 67, 1598\u20131610. https:\/\/doi.org\/10.1002\/art.39081 (2015).","journal-title":"Arthritis Rheumatol."},{"key":"85648_CR33","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1007\/s11926-021-00992-1","volume":"23","author":"A Zarfeshani","year":"2021","unstructured":"Zarfeshani, A., Carroll, K. R., Volpe, B. T. & Diamond, B. Cognitive impairment in SLE: Mechanisms and therapeutic approaches. Curr. Rheumatol. Rep. 23, 25. https:\/\/doi.org\/10.1007\/s11926-021-00992-1 (2021).","journal-title":"Curr. Rheumatol. Rep."},{"key":"85648_CR34","doi-asserted-by":"publisher","first-page":"1073","DOI":"10.1016\/j.cell.2018.05.003","volume":"173","author":"A Deczkowska","year":"2018","unstructured":"Deczkowska, A. et al. Disease-associated microglia: A universal immune sensor of neurodegeneration. Cell 173, 1073\u20131081. https:\/\/doi.org\/10.1016\/j.cell.2018.05.003 (2018).","journal-title":"Cell"},{"key":"85648_CR35","doi-asserted-by":"publisher","first-page":"504","DOI":"10.1038\/nn.4222","volume":"19","author":"K Grabert","year":"2016","unstructured":"Grabert, K. et al. Microglial brain region-dependent diversity and selective regional sensitivities to aging. Nat. Neurosci. 19, 504\u2013516. https:\/\/doi.org\/10.1038\/nn.4222 (2016).","journal-title":"Nat. Neurosci."},{"key":"85648_CR36","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1093\/cei\/uxac058","volume":"210","author":"P Nwaubani","year":"2022","unstructured":"Nwaubani, P., Cercignani, M. & Colasanti, A. In vivo quantitative imaging of hippocampal inflammation in autoimmune neuroinflammatory conditions: A systematic review. Clin. Exp. Immunol. 210, 24\u201338. https:\/\/doi.org\/10.1093\/cei\/uxac058 (2022).","journal-title":"Clin. Exp. Immunol."},{"key":"85648_CR37","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1016\/j.neulet.2018.04.050","volume":"680","author":"ZM Reagh","year":"2018","unstructured":"Reagh, Z. M. & Ranganath, C. What does the functional organization of cortico-hippocampal networks tell us about the functional organization of memory? Neurosci. Lett. 680, 69\u201376. https:\/\/doi.org\/10.1016\/j.neulet.2018.04.050 (2018).","journal-title":"Neurosci. Lett."},{"key":"85648_CR38","doi-asserted-by":"publisher","unstructured":"Pentari, A. et al. Altered hippocampal connectivity dynamics predicts memory performance in neuropsychiatric lupus: A resting-state fMRI study using cross-recurrence quantification analysis. Lupus Sci. Med. 10 https:\/\/doi.org\/10.1136\/lupus-2023-000920 (2023).","DOI":"10.1136\/lupus-2023-000920"},{"key":"85648_CR39","doi-asserted-by":"publisher","first-page":"3634","DOI":"10.1038\/s41380-020-00907-z","volume":"26","author":"R Bonacchi","year":"2021","unstructured":"Bonacchi, R. et al. Resting state network functional connectivity abnormalities in systemic lupus erythematosus: Correlations with neuropsychiatric impairment. Mol. Psychiatry. 26, 3634\u20133645. https:\/\/doi.org\/10.1038\/s41380-020-00907-z (2021).","journal-title":"Mol. Psychiatry"},{"key":"85648_CR40","doi-asserted-by":"publisher","first-page":"1593","DOI":"10.1007\/s00234-022-02924-x","volume":"64","author":"E Papadaki","year":"2022","unstructured":"Papadaki, E. et al. Converging evidence of impaired brain function in systemic lupus erythematosus: Changes in perfusion dynamics and intrinsic functional connectivity. Neuroradiology 64, 1593\u20131604. https:\/\/doi.org\/10.1007\/s00234-022-02924-x (2022).","journal-title":"Neuroradiology"},{"key":"85648_CR41","doi-asserted-by":"publisher","first-page":"2349","DOI":"10.1523\/JNEUROSCI.5587-06.2007","volume":"27","author":"WW Seeley","year":"2007","unstructured":"Seeley, W. W. et al. Dissociable intrinsic connectivity networks for salience processing and executive control. J. Neurosci. 27, 2349\u20132356 (2007).","journal-title":"J. Neurosci."},{"key":"85648_CR42","doi-asserted-by":"publisher","first-page":"1286","DOI":"10.1016\/j.acra.2013.07.011","volume":"20","author":"P Cagnoli","year":"2013","unstructured":"Cagnoli, P. et al. Reduced Insular glutamine and N-acetylaspartate in systemic lupus erythematosus: A single-voxel (1)H-MR spectroscopy study. Acad. Radiol. 20, 1286\u20131296. https:\/\/doi.org\/10.1016\/j.acra.2013.07.011 (2013).","journal-title":"Acad. Radiol."},{"key":"85648_CR43","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1093\/rheumatology\/keab256","volume":"61","author":"M Barraclough","year":"2021","unstructured":"Barraclough, M., McKie, S., Parker, B., Elliott, R. & Bruce, I. N. The effects of disease activity on neuronal and behavioural cognitive processes in systemic lupus erythematosus. Rheumatol. (Oxford). 61, 195\u2013204. https:\/\/doi.org\/10.1093\/rheumatology\/keab256 (2021).","journal-title":"Rheumatol. (Oxford)"},{"key":"85648_CR44","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1016\/j.autrev.2014.11.001","volume":"14","author":"N Sarbu","year":"2015","unstructured":"Sarbu, N. et al. Brain abnormalities in newly diagnosed neuropsychiatric lupus: Systematic MRI approach and correlation with clinical and laboratory data in a large multicenter cohort. Autoimmun. Rev. 14, 153\u2013159. https:\/\/doi.org\/10.1016\/j.autrev.2014.11.001 (2015).","journal-title":"Autoimmun. Rev."},{"key":"85648_CR45","doi-asserted-by":"publisher","first-page":"1837","DOI":"10.1002\/cne.24656","volume":"527","author":"J Nystedt","year":"2019","unstructured":"Nystedt, J. et al. Functional connectivity changes in core resting state networks are associated with cognitive performance in systemic lupus erythematosus. J. Comput. Neurol. 527, 1837\u20131856. https:\/\/doi.org\/10.1002\/cne.24656 (2019).","journal-title":"J. Comp. Neurol."},{"key":"85648_CR46","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1186\/s41824-021-00112-3","volume":"5","author":"AC Trevisan","year":"2021","unstructured":"Trevisan, A. C. et al. Temporal and spatial changes in cerebral blood flow in neuropsychiatric systemic lupus erythematosus: A subtraction brain spect study. Eur. J. Hybrid. Imaging. 5, 19. https:\/\/doi.org\/10.1186\/s41824-021-00112-3 (2021).","journal-title":"Eur. J. Hybrid. Imaging"},{"key":"85648_CR47","doi-asserted-by":"publisher","first-page":"1371","DOI":"10.1038\/s41593-019-0436-x","volume":"22","author":"M King","year":"2019","unstructured":"King, M., Hernandez-Castillo, C. R., Poldrack, R. A., Ivry, R. B. & Diedrichsen, J. Functional boundaries in the human cerebellum revealed by a multi-domain task battery. Nat. Neurosci. 22, 1371\u20131378. https:\/\/doi.org\/10.1038\/s41593-019-0436-x (2019).","journal-title":"Nat. Neurosci."},{"key":"85648_CR48","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1146\/annurev-neuro-070918-050258","volume":"42","author":"JD Schmahmann","year":"2019","unstructured":"Schmahmann, J. D., Guell, X., Stoodley, C. J. & Halko, M. A. The theory and neuroscience of cerebellar cognition. Annu. Rev. Neurosci. 42, 337\u2013364. https:\/\/doi.org\/10.1146\/annurev-neuro-070918-050258 (2019).","journal-title":"Annu. Rev. Neurosci."}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-85648-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-85648-1","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-85648-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,8]],"date-time":"2025-01-08T07:09:30Z","timestamp":1736320170000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-85648-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,8]]},"references-count":48,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["85648"],"URL":"https:\/\/doi.org\/10.1038\/s41598-025-85648-1","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-4604351\/v1","asserted-by":"object"}]},"ISSN":["2045-2322"],"issn-type":[{"value":"2045-2322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,8]]},"assertion":[{"value":"19 June 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 January 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 January 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"The study was approved by the Ethics Committee of the First Hospital of China Medical University (No.2022-306-02), and informed consent was obtained in writing from each participant.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical statement"}}],"article-number":"1310"}}