{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T09:01:58Z","timestamp":1783414918241,"version":"3.54.6"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,2,20]],"date-time":"2025-02-20T00:00:00Z","timestamp":1740009600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,2,20]],"date-time":"2025-02-20T00:00:00Z","timestamp":1740009600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"DOI":"10.13039\/501100004761","name":"the Natural Science Foundation of Hunan Province","doi-asserted-by":"crossref","award":["2024JJ5515"],"award-info":[{"award-number":["2024JJ5515"]}],"id":[{"id":"10.13039\/501100004761","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100004761","name":"the Natural Science Foundation of Hunan Province","doi-asserted-by":"crossref","award":["2022JJ30874"],"award-info":[{"award-number":["2022JJ30874"]}],"id":[{"id":"10.13039\/501100004761","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100004761","name":"the Natural Science Foundation of Hunan Province","doi-asserted-by":"crossref","award":["2024JJ5515"],"award-info":[{"award-number":["2024JJ5515"]}],"id":[{"id":"10.13039\/501100004761","id-type":"DOI","asserted-by":"crossref"}]},{"name":"the Key Research and Development program of Hunan Province","award":["2022SK2029"],"award-info":[{"award-number":["2022SK2029"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"DOI":"10.1038\/s41598-025-89964-4","type":"journal-article","created":{"date-parts":[[2025,2,20]],"date-time":"2025-02-20T12:00:08Z","timestamp":1740052808000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Relationship between vascular aging and left ventricular geometry in patients with obstructive sleep apnea hypopnea syndrome-related hypertension"],"prefix":"10.1038","volume":"15","author":[{"given":"Tao","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianwei","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiexiong","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ru","family":"Fu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liping","family":"Peng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaogang","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weihong","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,2,20]]},"reference":[{"key":"89964_CR1","doi-asserted-by":"publisher","unstructured":"Shao, H., Shen, P. & Chen, J. Expression profile analysis and image observation of miRNA in serum of patients with obstructive sleep apnea-hypopnea syndrome. Contrast Media Mol. Imaging 2021 (9731502). https:\/\/doi.org\/10.1155\/2021\/9731502 (2021).","DOI":"10.1155\/2021\/9731502"},{"key":"89964_CR2","doi-asserted-by":"publisher","first-page":"6909","DOI":"10.2147\/ijgm.S360544","volume":"15","author":"DS Sun","year":"2022","unstructured":"Sun, D. S. et al. The weighted combination of the epworth sleepiness scale and the STOP-Bang questionnaire improved the predictive value of for OSAHS in hypertensive patients. Int. J. Gen. Med. 15, 6909\u20136915. https:\/\/doi.org\/10.2147\/ijgm.S360544 (2022).","journal-title":"Int. J. Gen. Med."},{"key":"89964_CR3","doi-asserted-by":"publisher","first-page":"237","DOI":"10.5114\/aoms\/156490","volume":"19","author":"X Wang","year":"2023","unstructured":"Wang, X., Guan, L., Wu, C., Zhao, Y. & Zhao, G. Continuous positive airway pressure may improve hypertension in patients with obstructive sleep apnea-hypopnea syndrome by inhibiting inflammation and oxidative stress. Arch. Med. Sci. 19, 237\u2013241. https:\/\/doi.org\/10.5114\/aoms\/156490 (2023).","journal-title":"Arch. Med. Sci."},{"key":"89964_CR4","doi-asserted-by":"publisher","first-page":"e56","DOI":"10.1161\/cir.0000000000000988","volume":"144","author":"Y Yeghiazarians","year":"2021","unstructured":"Yeghiazarians, Y. et al. Obstructive sleep apnea and cardiovascular disease: A scientific statement from the american heart association. Circulation 144, e56\u2013e67. https:\/\/doi.org\/10.1161\/cir.0000000000000988 (2021).","journal-title":"Circulation"},{"key":"89964_CR5","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1016\/j.smrv.2016.07.002","volume":"34","author":"CV Senaratna","year":"2017","unstructured":"Senaratna, C. V. et al. Prevalence of obstructive sleep apnea in the general population: A systematic review. Sleep. Med. Rev. 34, 70\u201381. https:\/\/doi.org\/10.1016\/j.smrv.2016.07.002 (2017).","journal-title":"Sleep. Med. Rev."},{"key":"89964_CR6","doi-asserted-by":"publisher","unstructured":"Li, Y., Miao, Y., Tan, J. & Zhang, Q. Association of modifiable risk factors with obstructive sleep apnea: a mendelian randomization study. Aging (Albany NY) 15 https:\/\/doi.org\/10.18632\/aging.205288 (2023).","DOI":"10.18632\/aging.205288"},{"key":"89964_CR7","doi-asserted-by":"publisher","first-page":"12251","DOI":"10.21037\/apm-21-3302","volume":"10","author":"F Yuan","year":"2021","unstructured":"Yuan, F., Zhang, S., Liu, X. & Liu, Y. Correlation between obstructive sleep apnea hypopnea syndrome and hypertension: A systematic review and meta-analysis. Ann. Palliat. Med. 10, 12251\u201312261. https:\/\/doi.org\/10.21037\/apm-21-3302 (2021).","journal-title":"Ann. Palliat. Med."},{"key":"89964_CR8","doi-asserted-by":"publisher","first-page":"695","DOI":"10.1111\/j.1745-7599.2012.00771.x","volume":"24","author":"BL Goodson","year":"2012","unstructured":"Goodson, B. L., Wung, S. F. & Archbold, K. H. Obstructive sleep apnea hypopnea syndrome and metabolic syndrome: A synergistic cardiovascular risk factor. J. Am. Acad. Nurse Pract. 24, 695\u2013703. https:\/\/doi.org\/10.1111\/j.1745-7599.2012.00771.x (2012).","journal-title":"J. Am. Acad. Nurse Pract."},{"key":"89964_CR9","doi-asserted-by":"publisher","unstructured":"Zota, I. M. et al. Short-term CPAP improves biventricular function in patients with moderate-severe OSA and Cardiometabolic Comorbidities. Diagnostics (Basel) 11 https:\/\/doi.org\/10.3390\/diagnostics11050889 (2021).","DOI":"10.3390\/diagnostics11050889"},{"key":"89964_CR10","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1186\/s12872-021-02005-6","volume":"21","author":"YJ Choi","year":"2021","unstructured":"Choi, Y. J. et al. Prognostic implications of left ventricular mass-geometry in patients with no or nonobstructive coronary artery disease. BMC Cardiovasc. Disord. 21, 187. https:\/\/doi.org\/10.1186\/s12872-021-02005-6 (2021).","journal-title":"BMC Cardiovasc. Disord"},{"key":"89964_CR11","doi-asserted-by":"publisher","first-page":"17","DOI":"10.2478\/jtim-2021-0002","volume":"9","author":"Y Qiu","year":"2021","unstructured":"Qiu, Y., Liu, Y. & Tao, J. Progress of clinical evaluation for vascular aging in humans. J. Transl Int. Med. 9, 17\u201323. https:\/\/doi.org\/10.2478\/jtim-2021-0002 (2021).","journal-title":"J. Transl Int. Med."},{"key":"89964_CR12","doi-asserted-by":"publisher","first-page":"853","DOI":"10.2147\/cia.S248816","volume":"15","author":"R Maimaitiaili","year":"2020","unstructured":"Maimaitiaili, R. et al. Relationship between vascular aging and left ventricular concentric geometry in community-dwelling elderly: The Northern Shanghai study. Clin. Interv Aging. 15, 853\u2013863. https:\/\/doi.org\/10.2147\/cia.S248816 (2020).","journal-title":"Clin. Interv Aging"},{"key":"89964_CR13","doi-asserted-by":"publisher","first-page":"705","DOI":"10.1177\/0003319708329337","volume":"60","author":"V Di Bello","year":"2009","unstructured":"Di Bello, V. et al. Carotid intima-media thickness in asymptomatic patients with arterial hypertension without clinical cardiovascular disease: Relation with left ventricular geometry and mass and coexisting risk factors. Angiology 60, 705\u2013713. https:\/\/doi.org\/10.1177\/0003319708329337 (2009).","journal-title":"Angiology"},{"key":"89964_CR14","doi-asserted-by":"publisher","DOI":"10.3760\/cma.j.issn.1001-0939.2009.01.008","author":"YH Gao","year":"2009","unstructured":"Gao, Y. H. & He, A. Definitions of several terms related to smoking. Chin. J. Tuberculosis Respiratory Dis. https:\/\/doi.org\/10.3760\/cma.j.issn.1001-0939.2009.01.008 (2009).","journal-title":"Chin. J. Tuberculosis Respiratory Dis."},{"key":"89964_CR15","doi-asserted-by":"publisher","first-page":"898","DOI":"10.3760\/cma.j.issn.0254-6450.2018.07.007","volume":"39","author":"YR Li","year":"2018","unstructured":"Li, Y. R. et al. Drinking habits and influencing factors among Chinese adults. Chin. J. Epidemiol. 39, 898\u2013903. https:\/\/doi.org\/10.3760\/cma.j.issn.0254-6450.2018.07.007 (2018).","journal-title":"Chin. J. Epidemiol."},{"key":"89964_CR16","doi-asserted-by":"publisher","first-page":"247","DOI":"10.7326\/0003-4819-145-4-200608150-00004","volume":"145","author":"AS Levey","year":"2006","unstructured":"Levey, A. S. et al. Using standardized serum creatinine values in the modification of diet in renal disease study equation for estimating glomerular filtration rate. Ann. Intern. Med. 145, 247\u2013254. https:\/\/doi.org\/10.7326\/0003-4819-145-4-200608150-00004 (2006).","journal-title":"Ann. Intern. Med."},{"key":"89964_CR17","doi-asserted-by":"publisher","first-page":"o619","DOI":"10.1136\/bmj.o619","volume":"376","author":"Obstructive sleep apnoea\/hypopnoea","year":"2022","unstructured":"Obstructive sleep apnoea\/hypopnoea. Syndrome and obesity hypoventilation syndrome in over 16s: Summary of NICE guidance. Bmj 376, o619. https:\/\/doi.org\/10.1136\/bmj.o619 (2022).","journal-title":"Bmj"},{"key":"89964_CR18","doi-asserted-by":"publisher","first-page":"313","DOI":"10.3969\/j.issn.1000-3614.2021.04.001","volume":"36","author":"Working group on the chinese hypertension league guidelines for ambulatory blood pressure monitoring","year":"2021","unstructured":"Working group on the chinese hypertension league guidelines for ambulatory blood pressure monitoring. 2020 Chinese guidelines for ambulatory blood pressure monitoring. Chin. Circ. J. 36, 313\u2013328. https:\/\/doi.org\/10.3969\/j.issn.1000-3614.2021.04.001 (2021).","journal-title":"Chin. Circ. J."},{"key":"89964_CR19","doi-asserted-by":"publisher","first-page":"2588","DOI":"10.1093\/eurheartj\/ehl254","volume":"27","author":"S Laurent","year":"2006","unstructured":"Laurent, S. et al. Expert consensus document on arterial stiffness: Methodological issues and clinical applications. Eur. Heart J. 27, 2588\u20132605. https:\/\/doi.org\/10.1093\/eurheartj\/ehl254 (2006).","journal-title":"Eur. Heart J."},{"key":"89964_CR20","doi-asserted-by":"publisher","first-page":"1025","DOI":"10.1016\/j.jcmg.2013.11.014","volume":"7","author":"TZ Naqvi","year":"2014","unstructured":"Naqvi, T. Z. & Lee, M. S. Carotid intima-media thickness and plaque in cardiovascular risk assessment. JACC Cardiovasc. Imaging 7, 1025\u20131038. https:\/\/doi.org\/10.1016\/j.jcmg.2013.11.014 (2014).","journal-title":"JACC Cardiovasc. Imaging"},{"key":"89964_CR21","first-page":"295","volume":"9","author":"M Rac-Albu","year":"2014","unstructured":"Rac-Albu, M., Iliuta, L., Guberna, S. M. & Sinescu, C. The role of ankle-brachial index for predicting peripheral arterial disease. Maedica (Bucur) 9, 295\u2013302 (2014).","journal-title":"Maedica (Bucur)"},{"key":"89964_CR22","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s44325-023-00001-7","volume":"1","author":"W Song","year":"2024","unstructured":"Song, W. et al. Association between brachial-ankle pulse wave velocity and the risk of new-onset atrial fibrillation: A report from Kailuan prospective cohort study. Npj Cardiovasc. Health 1, 1. https:\/\/doi.org\/10.1038\/s44325-023-00001-7 (2024).","journal-title":"Npj Cardiovasc. Health"},{"key":"89964_CR23","doi-asserted-by":"publisher","unstructured":"Zyriax, B. C., Dransfeld, K. & Windler, E. Carotid intima\u2013media thickness and cardiovascular risk factors in healthy volunteers. Ultrasound J. 13 https:\/\/doi.org\/10.1186\/s13089-021-00218-6 (2021).","DOI":"10.1186\/s13089-021-00218-6"},{"key":"89964_CR24","doi-asserted-by":"publisher","first-page":"412","DOI":"10.1093\/ehjci\/jew041","volume":"17","author":"Recommendations for Cardiac Chamber Quantification by Echocardiography in Adults","year":"2016","unstructured":"Recommendations for Cardiac Chamber Quantification by Echocardiography in Adults. An update from the american society of echocardiography and the european association of, cardiovascular imaging. Eur. Heart J. Cardiovasc. Imaging. 17, 412. https:\/\/doi.org\/10.1093\/ehjci\/jew041 (2016).","journal-title":"Eur. Heart J. Cardiovasc. Imaging"},{"key":"89964_CR25","doi-asserted-by":"publisher","first-page":"961882","DOI":"10.3389\/fendo.2022.961882","volume":"13","author":"M Huang","year":"2022","unstructured":"Huang, M. et al. Relationship between vascular ageing and left ventricular geometry in patients with newly diagnosed primary aldosteronism. Front. Endocrinol. (Lausanne) 13, 961882. https:\/\/doi.org\/10.3389\/fendo.2022.961882 (2022).","journal-title":"Front. Endocrinol. (Lausanne)"},{"key":"89964_CR26","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1186\/s13047-019-0350-1","volume":"12","author":"S Casey","year":"2019","unstructured":"Casey, S., Lanting, S., Oldmeadow, C. & Chuter, V. The reliability of the ankle brachial index: A systematic review. J. Foot Ankle Res. 12, 39. https:\/\/doi.org\/10.1186\/s13047-019-0350-1 (2019).","journal-title":"J. Foot Ankle Res."},{"key":"89964_CR27","doi-asserted-by":"publisher","unstructured":"Ma, L., Zhang, J. & Liu, Y. Roles and mechanisms of obstructive sleep apnea-hypopnea syndrome and chronic intermittent hypoxia in atherosclerosis: Evidence and prospective. Oxid. Med. Cell. Longev. 2016 (8215082). https:\/\/doi.org\/10.1155\/2016\/8215082 (2016).","DOI":"10.1155\/2016\/8215082"},{"key":"89964_CR28","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1186\/1476-7120-11-2","volume":"11","author":"HL Kim","year":"2013","unstructured":"Kim, H. L. et al. The association between arterial stiffness and left ventricular filling pressure in an apparently healthy Korean population. Cardiovasc. Ultrasound 11, 2. https:\/\/doi.org\/10.1186\/1476-7120-11-2 (2013).","journal-title":"Cardiovasc. Ultrasound"}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-89964-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-89964-4","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-89964-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,20]],"date-time":"2025-02-20T12:00:15Z","timestamp":1740052815000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-89964-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,20]]},"references-count":28,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["89964"],"URL":"https:\/\/doi.org\/10.1038\/s41598-025-89964-4","relation":{},"ISSN":["2045-2322"],"issn-type":[{"value":"2045-2322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2,20]]},"assertion":[{"value":"12 June 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 February 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 February 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"We declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"6191"}}