{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T21:54:51Z","timestamp":1787003691370,"version":"build-2736575974"},"reference-count":19,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T00:00:00Z","timestamp":1744156800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T00:00:00Z","timestamp":1744156800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"With Healthcare"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    The purpose of study was to evaluate the diagnostic value of the ZTE sequence of shoulder MRI in patients with calcific tendinitis by comparing conventional sequences. Seventy-nine patients (43 patients with calcific tendinitis and 36 control group) who underwent both radiography and MRI including ZTE sequence were enrolled in our study. Two radiologists assessed the SNR, image quality, presence, size, multiplicity, shape, margin, signal intensity, composition, and location of calcific deposits on ZTE image, FSPDWI, and T2WI. The diagnostic performance was calculated with radiography as the standard of reference. The inter-reader agreement and differentiation of the resorptive phase and formative phase on ZTE were compared to that on FSPDWI and T2WI. A total 59 calcific deposits in 43 patients were found on radiography and classified into type 1 resorptive phases (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200920) and type 2 formative phases (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200939). ZTE image quality was for diagnostic use with substantial inter-reader agreement. Sensitivity and detection rate of ZTE image was better than those of FSPDWI and T2WI. The inter-reader agreement of ZTE image was equal to FSPDWI and better than T2WI. The features of calcific deposits on ZTE images were significantly different between two phases. In the resorptive phase, a greater percentage of calcific deposits showed irregular shapes, ill-defined margin, heterogeneous compositions on ZTE images. In conclusion, ZTE sequence may provide useful information for the diagnosis of calcific tendinitis of the shoulder.\n                  <\/jats:p>","DOI":"10.1038\/s41598-025-91983-0","type":"journal-article","created":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T01:49:31Z","timestamp":1744163371000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["ZTE MRI improves detection of calcific deposits and differentiation between resorptive and formative phases in calcific tendinitis of shoulder"],"prefix":"10.1038","volume":"15","author":[{"given":"Ji Young","family":"Hwang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyein","family":"Yun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"In Na","family":"Yoon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min-Yung","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minseong","family":"Kang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang-Jin","family":"Shin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moon jung","family":"Hwang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,4,9]]},"reference":[{"key":"91983_CR1","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1007\/s10195-015-0367-6","volume":"17","author":"G Merolla","year":"2016","unstructured":"Merolla, G., Singh, S., Paladini, P. & Porcellini, G. Calcific tendinitis of the rotator cuff: state of the Art in diagnosis and treatment. J. Orthop. Traumatol. 17, 7\u201314. https:\/\/doi.org\/10.1007\/s10195-015-0367-6 (2016).","journal-title":"J. Orthop. Traumatol."},{"key":"91983_CR2","doi-asserted-by":"publisher","first-page":"1588","DOI":"10.1016\/j.jse.2015.02.024","volume":"24","author":"JK Louwerens","year":"2015","unstructured":"Louwerens, J. K., Sierevelt, I. N., van Hove, R. P., van den Bekerom, M. P. & van Noort, A. Prevalence of calcific deposits within the rotator cuff tendons in adults with and without subacromial pain syndrome: clinical and radiologic analysis of 1219 patients. J. Shoulder Elb. Surg. 24, 1588\u20131593. https:\/\/doi.org\/10.1016\/j.jse.2015.02.024 (2015).","journal-title":"J. Shoulder Elb. Surg."},{"key":"91983_CR3","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1016\/0749-8063(92)90034-9","volume":"8","author":"JW Ark","year":"1992","unstructured":"Ark, J. W., Flock, T. J., Flatow, E. L. & Bigliani, L. U. Arthroscopic treatment of calcific tendinitis of the shoulder. Arthroscopy 8, 183\u2013188. https:\/\/doi.org\/10.1016\/0749-8063(92)90034-9 (1992).","journal-title":"Arthroscopy"},{"key":"91983_CR4","doi-asserted-by":"publisher","first-page":"567","DOI":"10.1016\/S0950-3579(89)80009-3","volume":"3","author":"HK Uhthof","year":"1989","unstructured":"Uhthof, H. K. & Sarkar, K. Calcifying tendinitis. Baillieres Clin. Rheumatol. 3, 567\u2013581 (1989).","journal-title":"Baillieres Clin. Rheumatol."},{"key":"91983_CR5","doi-asserted-by":"publisher","first-page":"608","DOI":"10.1007\/s11547-020-01300-0","volume":"126","author":"D Albano","year":"2021","unstructured":"Albano, D. et al. Imaging of calcific tendinopathy around the shoulder: usual and unusual presentations and common pitfalls. Radiol. Med. 126, 608\u2013619. https:\/\/doi.org\/10.1007\/s11547-020-01300-0 (2021).","journal-title":"Radiol. Med."},{"key":"91983_CR6","doi-asserted-by":"publisher","first-page":"6381","DOI":"10.1007\/s00330-023-09602-3","volume":"33","author":"U Puel","year":"2023","unstructured":"Puel, U. et al. Zero echo time MRI in shoulder MRI protocols for the diagnosis of rotator cuff calcific tendinopathy improves identification of calcific deposits compared to conventional MR sequences but remains sub-optimal compared to radiographs. Eur. Radiol. 33, 6381\u20136391. https:\/\/doi.org\/10.1007\/s00330-023-09602-3 (2023).","journal-title":"Eur. Radiol."},{"key":"91983_CR7","first-page":"61","volume":"20","author":"AF DePalma","year":"1961","unstructured":"DePalma, A. F. & Kruper, J. S. Long-term study of shoulder joints afflicted with and treated for calcific tendinitis. Clin. Orthop. 20, 61\u201372 (1961).","journal-title":"Clin. Orthop."},{"key":"91983_CR8","doi-asserted-by":"publisher","first-page":"7","DOI":"10.7863\/jum.1995.14.1.7","volume":"14","author":"PU Farin","year":"1995","unstructured":"Farin, P. U. & Jaroma, H. Sonographic findings of rotator cuff calcifications. J. Ultrasound Med. 14, 7\u201314. https:\/\/doi.org\/10.7863\/jum.1995.14.1.7 (1995).","journal-title":"J. Ultrasound Med."},{"key":"91983_CR9","doi-asserted-by":"publisher","first-page":"1603","DOI":"10.1007\/s00330-006-0428-6","volume":"17","author":"C Zubler","year":"2007","unstructured":"Zubler, C. et al. MR arthrography in calcific tendinitis of the shoulder: diagnostic performance and pitfalls. Eur. Radiol. 17, 1603\u20131610. https:\/\/doi.org\/10.1007\/s00330-006-0428-6 (2007).","journal-title":"Eur. Radiol."},{"key":"91983_CR10","doi-asserted-by":"publisher","first-page":"109","DOI":"10.3174\/ajnr.A5916","volume":"40","author":"SB Cho","year":"2019","unstructured":"Cho, S. B. et al. Clinical feasibility of zero TE skull MRI in patients with head trauma in comparison with CT: A Single-Center study. Am. J. Neuroradiol. 40, 109\u2013115 (2019).","journal-title":"Am. J. Neuroradiol."},{"key":"91983_CR11","doi-asserted-by":"publisher","first-page":"960","DOI":"10.1148\/radiol.2017170906","volume":"286","author":"RE Breighner","year":"2018","unstructured":"Breighner, R. E. et al. Technical developments: zero echo time imaging of the shoulder: enhanced osseous detail by using MR imaging. Radiology 286, 960\u2013966. https:\/\/doi.org\/10.1148\/radiol.2017170906 (2018).","journal-title":"Radiology"},{"key":"91983_CR12","doi-asserted-by":"publisher","first-page":"2391","DOI":"10.1016\/j.arthro.2020.05.042","volume":"36","author":"RAF de Mello","year":"2020","unstructured":"de Mello, R. A. F. et al. Three-Dimensional zero echo time magnetic resonance imaging versus 3-Dimensional computed tomography for glenoid bone assessment. Arthroscopy: J. Arthroscopic Relat. Surg. 36, 2391\u20132400. https:\/\/doi.org\/10.1016\/j.arthro.2020.05.042 (2020).","journal-title":"Arthroscopy: J. Arthroscopic Relat. Surg."},{"key":"91983_CR13","doi-asserted-by":"publisher","first-page":"3460","DOI":"10.1177\/0363546519878170","volume":"47","author":"RE Breighner","year":"2019","unstructured":"Breighner, R. E., Bogner, E. A., Lee, S. C., Koff, M. F. & Potter, H. G. Evaluation of osseous morphology of the hip using zero echo time magnetic resonance imaging. Am. J. Sports Med. 47, 3460\u20133468. https:\/\/doi.org\/10.1177\/0363546519878170 (2019).","journal-title":"Am. J. Sports Med."},{"key":"91983_CR14","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1148\/radiol.2282011860","volume":"228","author":"HL Kundel","year":"2003","unstructured":"Kundel, H. L. & Polansky, M. Measurement of observer agreement. Radiology 228, 303\u2013308. https:\/\/doi.org\/10.1148\/radiol.2282011860 (2003).","journal-title":"Radiology"},{"key":"91983_CR15","doi-asserted-by":"publisher","first-page":"304","DOI":"10.1016\/j.jmr.2010.09.013","volume":"207","author":"J Du","year":"2010","unstructured":"Du, J. et al. Qualitative and quantitative ultrashort echo time (UTE) imaging of cortical bone. J. Magn. Reson. 207, 304\u2013311. https:\/\/doi.org\/10.1016\/j.jmr.2010.09.013 (2010).","journal-title":"J. Magn. Reson."},{"key":"91983_CR16","unstructured":"Weiger, M. & Pruessmann, K. P. in Encyclopedia of Magnetic Resonance (2012)."},{"key":"91983_CR17","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1148\/radiol.2015150034","volume":"278","author":"D N\u00f6renberg","year":"2016","unstructured":"N\u00f6renberg, D. et al. Diagnosis of calcific tendonitis of the rotator cuff by using Susceptibility-weighted MR imaging. Radiology 278, 475\u2013484. https:\/\/doi.org\/10.1148\/radiol.2015150034 (2016).","journal-title":"Radiology"},{"key":"91983_CR18","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1186\/s10195-021-00604-9","volume":"22","author":"R Compagnoni","year":"2021","unstructured":"Compagnoni, R. et al. Long-term evolution of calcific tendinitis of the rotator cuff: clinical and radiological evaluation 10 years after diagnosis. J. Orthop. Traumatol. 22, 42. https:\/\/doi.org\/10.1186\/s10195-021-00604-9 (2021).","journal-title":"J. Orthop. Traumatol."},{"key":"91983_CR19","doi-asserted-by":"publisher","first-page":"210","DOI":"10.5397\/cise.2020.00318","volume":"23","author":"MS Kim","year":"2020","unstructured":"Kim, M. S., Kim, I. W., Lee, S. & Shin, S. J. Diagnosis and treatment of calcific tendinitis of the shoulder. Clin. Shoulder Elb. 23, 210\u2013216. https:\/\/doi.org\/10.5397\/cise.2020.00318 (2020).","journal-title":"Clin. Shoulder Elb."}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-91983-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-91983-0","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-91983-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T01:49:37Z","timestamp":1744163377000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-91983-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,9]]},"references-count":19,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["91983"],"URL":"https:\/\/doi.org\/10.1038\/s41598-025-91983-0","relation":{},"ISSN":["2045-2322"],"issn-type":[{"value":"2045-2322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,9]]},"assertion":[{"value":"3 March 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 February 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 April 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"12084"}}