{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T22:54:26Z","timestamp":1787871266806,"version":"build-2784847793"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,3,26]],"date-time":"2025-03-26T00:00:00Z","timestamp":1742947200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,3,26]],"date-time":"2025-03-26T00:00:00Z","timestamp":1742947200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"DOI":"10.1038\/s41598-025-94609-7","type":"journal-article","created":{"date-parts":[[2025,3,26]],"date-time":"2025-03-26T04:02:20Z","timestamp":1742961740000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Sagittal balance analysis and treatment rationale for young patients with symptomatic lumbosacral transitional vertebrae"],"prefix":"10.1038","volume":"15","author":[{"given":"Andreas","family":"Tsoupras","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Romain","family":"Dayer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hugo","family":"Bothorel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Faundez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,3,26]]},"reference":[{"issue":"2","key":"94609_CR1","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1148\/radiol.12112747","volume":"265","author":"L Nardo","year":"2012","unstructured":"Nardo, L. et al. Lumbosacral transitional vertebrae: association with low back pain. Radiology 265 (2), 497\u2013503 (2012).","journal-title":"Radiology"},{"issue":"11","key":"94609_CR2","doi-asserted-by":"crossref","first-page":"3630","DOI":"10.1007\/s00586-016-4485-5","volume":"25","author":"JC Le Huec","year":"2016","unstructured":"Le Huec, J. C. & Hasegawa, K. Normative values for the spine shape parameters using 3D standing analysis from a database of 268 asymptomatic Caucasian and Japanese subjects. Eur. Spine J. 25 (11), 3630\u20133637 (2016).","journal-title":"Eur. Spine J."},{"issue":"4","key":"94609_CR3","first-page":"191","volume":"58","author":"L Dai","year":"1999","unstructured":"Dai, L. Lumbosacral transitional vertebrae and low back pain. Bull. Hosp. Jt. Dis. 58 (4), 191\u2013193 (1999).","journal-title":"Bull. Hosp. Jt. Dis."},{"issue":"9","key":"94609_CR4","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1302\/0301-620X.88B9.17211","volume":"88","author":"JF Quinlan","year":"2006","unstructured":"Quinlan, J. F., Duke, D. & Eustace, S. Bertolotti\u2019s syndrome. A cause of back pain in young people. J. Bone Joint Surg. Br. 88 (9), 1183\u20131186 (2006).","journal-title":"J. Bone Joint Surg. Br."},{"issue":"6","key":"94609_CR5","doi-asserted-by":"crossref","first-page":"1210","DOI":"10.1016\/j.spinee.2013.10.029","volume":"15","author":"NA Farshad-Amacker","year":"2015","unstructured":"Farshad-Amacker, N. A., Herzog, R. J., Hughes, A. P., Aichmair, A. & Farshad, M. Associations between lumbosacral transitional anatomy types and degeneration at the transitional and adjacent segments. Spine J. 15 (6), 1210\u20131216 (2015).","journal-title":"Spine J."},{"issue":"5","key":"94609_CR6","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1097\/00007632-198407000-00014","volume":"9","author":"AE Castellvi","year":"1984","unstructured":"Castellvi, A. E., Goldstein, L. A. & Chan, D. P. Lumbosacral transitional vertebrae and their relationship with lumbar extradural defects. Spine (Phila Pa. 1976)  9 (5), 493\u2013495 (1984).","journal-title":"Spine (Phila Pa. 1976)"},{"issue":"11","key":"94609_CR7","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1302\/0301-620X.95B11.32331","volume":"95-B","author":"M Farshad","year":"2013","unstructured":"Farshad, M., Aichmair, A., Hughes, A. P., Herzog, R. J. & Farshad-Amacker, N. A. A reliable measurement for identifying a lumbosacral transitional vertebra with a solid bony Bridge on a single-slice midsagittal MRI or plain lateral radiograph. Bone Joint J. 95-B (11), 1533\u20131537 (2013).","journal-title":"Bone Joint J."},{"issue":"Suppl 5(Suppl 5","key":"94609_CR8","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1007\/s00586-011-1930-3","volume":"20","author":"C Barrey","year":"2011","unstructured":"Barrey, C., Roussouly, P., Perrin, G. & Le Huec, J. C. Sagittal balance disorders in severe degenerative spine. Can we identify the compensatory mechanisms? Eur. Spine J. 20 (Suppl 5(Suppl 5), 626\u2013633 (2011).","journal-title":"Eur. Spine J."},{"issue":"1","key":"94609_CR9","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1097\/01.bsd.0000117542.88865.77","volume":"18","author":"E Berthonnaud","year":"2005","unstructured":"Berthonnaud, E., Dimnet, J., Roussouly, P. & Labelle, H. Analysis of the sagittal balance of the spine and pelvis using shape and orientation parameters. J. Spinal Disord Tech. 18 (1), 40\u201347 (2005).","journal-title":"J. Spinal Disord Tech."},{"issue":"4","key":"94609_CR10","first-page":"123","volume":"12","author":"AM Jacob","year":"2023","unstructured":"Jacob, A. M. et al. Evaluation of spinopelvic parameters in patients with lumbosacral transitional vertebra: a cross sectional and comparative study. Am. J. Neurodegener. Dis. 12 (4), 123\u2013132 (2023).","journal-title":"Am. J. Neurodegener Dis."},{"issue":"8","key":"94609_CR11","doi-asserted-by":"crossref","first-page":"2952","DOI":"10.1007\/s00586-024-08378-4","volume":"33","author":"J Ouchida","year":"2024","unstructured":"Ouchida, J. et al. Analysis of spinopelvic parameters in adult patients with lumbosacral transitional vertebrae. Eur. Spine J. 33 (8), 2952\u20132959 (2024).","journal-title":"Eur. Spine J."},{"key":"94609_CR12","doi-asserted-by":"crossref","unstructured":"Verhaegen, J. C. F. et al. Prevalence of lumbosacral transitional vertebral anomalies among healthy volunteers and patients with hip pathology: association with spinopelvic characteristics. JB JS Open Access 8(1). (2023).","DOI":"10.2106\/JBJS.OA.22.00095"},{"issue":"4","key":"94609_CR13","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1097\/01.brs.0000153698.94091.f8","volume":"30","author":"WC Horton","year":"2005","unstructured":"Horton, W. C. et al. Is there an optimal patient stance for obtaining a lateral 36 radiograph? A critical comparison of three techniques. Spine 30 (4), 427\u2013433 (2005).","journal-title":"Spine"},{"issue":"20","key":"94609_CR14","doi-asserted-by":"crossref","first-page":"2284","DOI":"10.1097\/01.brs.0000142224.46796.a7","volume":"29","author":"FD Faro","year":"2004","unstructured":"Faro, F. D., Marks, M. C., Pawelek, J. & Newton, P. O. Evaluation of a functional position for lateral radiograph acquisition in adolescent idiopathic scoliosis. Spine 29 (20), 2284\u20132289 (2004).","journal-title":"Spine"},{"key":"94609_CR15","first-page":"111","volume":"11","author":"JC Risser","year":"1958","unstructured":"Risser, J. C. The Iliac apophysis; an invaluable sign in the management of scoliosis. Clin. Orthop. 11, 111\u2013119 (1958).","journal-title":"Clin. Orthop."},{"issue":"11","key":"94609_CR16","doi-asserted-by":"crossref","first-page":"3602","DOI":"10.1007\/s00586-015-4371-6","volume":"25","author":"D Dominguez","year":"2016","unstructured":"Dominguez, D., Faundez, A., Demezon, H., Cogniet, A. & Le Huec, J. C. Normative values for the L5 incidence in a subgroup of transitional anomalies extracted from 147 asymptomatic subjects. Eur. Spine J. 25 (11), 3602\u20133607 (2016).","journal-title":"Eur. Spine J."},{"issue":"8","key":"94609_CR17","doi-asserted-by":"crossref","first-page":"1603","DOI":"10.1097\/CORR.0000000000000380","volume":"476","author":"S Pesenti","year":"2018","unstructured":"Pesenti, S. et al. The amount of proximal lumbar lordosis is related to pelvic incidence. Clin. Orthop. Relat. Res. 476 (8), 1603\u20131611 (2018).","journal-title":"Clin. Orthop. Relat. Res."},{"issue":"9","key":"94609_CR18","doi-asserted-by":"crossref","first-page":"1551","DOI":"10.1007\/s00586-010-1422-x","volume":"19","author":"JY Hong","year":"2010","unstructured":"Hong, J. Y. et al. Reliability analysis for radiographic measures of lumbar lordosis in adult scoliosis: a case-control study comparing 6 methods. Eur. Spine J. 19 (9), 1551\u20131557 (2010).","journal-title":"Eur. Spine J."},{"issue":"24","key":"94609_CR19","doi-asserted-by":"crossref","first-page":"E708","DOI":"10.1097\/BRS.0b013e31815a59a0","volume":"32","author":"JF Griffith","year":"2007","unstructured":"Griffith, J. F. et al. Modified Pfirrmann grading system for lumbar intervertebral disc degeneration. Spine (Phila Pa. 1976). 32 (24), E708\u2013E712 (2007).","journal-title":"Spine (Phila Pa. 1976)"},{"issue":"3","key":"94609_CR20","doi-asserted-by":"crossref","first-page":"178","DOI":"10.3340\/jkns.2015.57.3.178","volume":"57","author":"I Jeon","year":"2015","unstructured":"Jeon, I. & Kim, S. W. Retrolisthesis as a compensatory mechanism in degenerative lumbar spine. J. Korean Neurosurg. Soc. 57 (3), 178\u2013184 (2015).","journal-title":"J. Korean Neurosurg. Soc."},{"issue":"7","key":"94609_CR21","doi-asserted-by":"crossref","first-page":"968","DOI":"10.2106\/00004623-197557070-00015","volume":"57","author":"HL Brooks","year":"1975","unstructured":"Brooks, H. L., Azen, S. P., Gerberg, E., Brooks, R. & Chan, L. Scoliosis: A prospective epidemiological study. J. Bone Joint Surg. Am. 57 (7), 968\u2013972 (1975).","journal-title":"J. Bone Joint Surg. Am."},{"issue":"5","key":"94609_CR22","doi-asserted-by":"crossref","first-page":"681","DOI":"10.14444\/7099","volume":"14","author":"CT Martin","year":"2020","unstructured":"Martin, C. T., Niu, S., Whicker, E., Ward, L. & Yoon, S. T. Radiographic factors affecting lordosis correction after transforaminal lumbar interbody fusion with unilateral facetectomy. Int. J. Spine Surg. 14 (5), 681\u2013686 (2020).","journal-title":"Int. J. Spine Surg."},{"issue":"1","key":"94609_CR23","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1186\/s13018-018-0737-x","volume":"13","author":"F Zhang","year":"2018","unstructured":"Zhang, F. et al. Correlation between lumbar intervertebral disc height and lumbar spine sagittal alignment among asymptomatic Asian young adults. J. Orthop. Surg. Res. 13 (1), 34 (2018).","journal-title":"J. Orthop. Surg. Res."},{"issue":"2","key":"94609_CR24","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1097\/01.BRS.0000107223.02346.A8","volume":"29","author":"K Luoma","year":"2004","unstructured":"Luoma, K., Vehmas, T., Raininko, R., Luukkonen, R. & Riihim\u00e4ki, H. Lumbosacral transitional vertebra: relation to disc degeneration and low back pain. Spine (Phila Pa. 1976)  29 (2), 200\u2013205 (2004).","journal-title":"Spine (Phila Pa. 1976)"},{"issue":"5","key":"94609_CR25","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1302\/0301-620X.87B5.15727","volume":"87","author":"T Aihara","year":"2005","unstructured":"Aihara, T. et al. Intervertebral disc degeneration associated with lumbosacral transitional vertebrae: a clinical and anatomical study. J. Bone Joint Surg. Br. 87 (5), 687\u2013691 (2005).","journal-title":"J. Bone Joint Surg. Br."},{"issue":"1","key":"94609_CR26","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1111\/papr.13280","volume":"24","author":"I Coskun Benlidayi","year":"2024","unstructured":"Coskun Benlidayi, I. & Tirasci, E. The effect of lumbosacral transitional vertebra on lumbar spine degeneration and spondylolisthesis among patients with low back pain. Pain Pract. 24 (1), 52\u201361 (2024).","journal-title":"Pain Pract."},{"issue":"1","key":"94609_CR27","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1186\/s12891-024-07318-z","volume":"25","author":"M Mahmoodkhani","year":"2024","unstructured":"Mahmoodkhani, M., Naeimi, A., Zohrevand, A., Rabbanifard, A. & Rezvani, M. Lumbosacral transitional vertebra in spondylolisthesis: frequency, demographic findings, and clinical characteristics. BMC Musculoskelet. Disord. 25 (1), 243 (2024).","journal-title":"BMC Musculoskelet. Disord"},{"issue":"3","key":"94609_CR28","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1007\/s00586-019-06183-y","volume":"29","author":"C Pan","year":"2020","unstructured":"Pan, C., Wang, G. & Sun, J. Correlation between the apex of lumbar lordosis and pelvic incidence in asymptomatic adult. Eur. Spine J. 29 (3), 420\u2013427 (2020).","journal-title":"Eur. Spine J."},{"key":"94609_CR29","doi-asserted-by":"crossref","unstructured":"Ludwig, O., Dindorf, C., Kelm, S., Kelm, J. & Fr\u00f6hlich, M. Muscular strategies for correcting the pelvic position to improve posture\u2014An exploratory study. J. Funct. Morphol. Kinesiol. ;9(1). (2024).","DOI":"10.3390\/jfmk9010025"},{"issue":"9","key":"94609_CR30","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1589\/jpts.32.601","volume":"32","author":"PA Oakley","year":"2020","unstructured":"Oakley, P. A., Ehsani, N. N., Moustafa, I. M. & Harrison, D. E. Restoring lumbar Lordosis: a systematic review of controlled trials utilizing chiropractic bio physics(\u00ae) (CBP(\u00ae)) non-surgical approach to increasing lumbar lordosis in the treatment of low back disorders. J. Phys. Ther. Sci. 32 (9), 601\u2013610 (2020).","journal-title":"J. Phys. Ther. Sci."},{"issue":"9","key":"94609_CR31","doi-asserted-by":"crossref","first-page":"1889","DOI":"10.1007\/s00586-019-06083-1","volume":"28","author":"JC Le Huec","year":"2019","unstructured":"Le Huec, J. C., Thompson, W., Mohsinaly, Y., Barrey, C. & Faundez, A. Sagittal balance of the spine. Eur. Spine J. 28 (9), 1889\u20131905 (2019).","journal-title":"Eur. Spine J."},{"key":"94609_CR32","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.clinbiomech.2017.09.008","volume":"49","author":"M Masaki","year":"2017","unstructured":"Masaki, M. et al. Association of low back pain with muscle stiffness and muscle mass of the lumbar back muscles, and sagittal spinal alignment in young and middle-aged medical workers. Clin. Biomech. (Bristol Avon). 49, 128\u2013133 (2017).","journal-title":"Clin. Biomech. (Bristol Avon)"}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-94609-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-94609-7","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-94609-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,26]],"date-time":"2025-03-26T04:03:14Z","timestamp":1742961794000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-94609-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,26]]},"references-count":32,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["94609"],"URL":"https:\/\/doi.org\/10.1038\/s41598-025-94609-7","relation":{},"ISSN":["2045-2322"],"issn-type":[{"value":"2045-2322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3,26]]},"assertion":[{"value":"18 November 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 March 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 March 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"The study was approved by the cantonal ethics committee (2023\u2009\u2212\u200900978) as all the subjects, or their parent and legal guardian had provided a written informed consent form allowing the use of their data in research projects. Moreover, the authors affirm that human research participants provided informed consent for publication of the images in (Figs.\u00a01 and 5). All methods and analysis were performed in accordance with the relevant guidelines and regulations.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Human ethics and consent to participate declaration"}}],"article-number":"10357"}}