{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T14:51:07Z","timestamp":1793717467332,"version":"4.6.1"},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,4,29]],"date-time":"2025-04-29T00:00:00Z","timestamp":1745884800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,4,29]],"date-time":"2025-04-29T00:00:00Z","timestamp":1745884800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"name":"Korean government","award":["RS-2023-00264409"],"award-info":[{"award-number":["RS-2023-00264409"]}]},{"name":"Korean government","award":["RS-2023-00264409"],"award-info":[{"award-number":["RS-2023-00264409"]}]},{"name":"Korean government","award":["RS-2023-00264409"],"award-info":[{"award-number":["RS-2023-00264409"]}]},{"name":"Korean government","award":["RS-2023-00264409"],"award-info":[{"award-number":["RS-2023-00264409"]}]},{"name":"Korean government","award":["RS-2023-00264409"],"award-info":[{"award-number":["RS-2023-00264409"]}]},{"name":"Korean government","award":["RS-2023-00264409"],"award-info":[{"award-number":["RS-2023-00264409"]}]},{"name":"Korean government","award":["RS-2023-00264409"],"award-info":[{"award-number":["RS-2023-00264409"]}]},{"name":"Korean government","award":["RS-2023-00264409"],"award-info":[{"award-number":["RS-2023-00264409"]}]},{"name":"AI-based GIST Research Scientist Project grant","award":["2025"],"award-info":[{"award-number":["2025"]}]},{"name":"AI-based GIST Research Scientist Project grant","award":["2025"],"award-info":[{"award-number":["2025"]}]},{"name":"AI-based GIST Research Scientist Project grant","award":["2025"],"award-info":[{"award-number":["2025"]}]},{"name":"AI-based GIST Research Scientist Project grant","award":["2025"],"award-info":[{"award-number":["2025"]}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["RS-2025-00573499"],"award-info":[{"award-number":["RS-2025-00573499"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["RS-2025-00573499"],"award-info":[{"award-number":["RS-2025-00573499"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["RS-2025-00573499"],"award-info":[{"award-number":["RS-2025-00573499"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["RS-2025-00522868"],"award-info":[{"award-number":["RS-2025-00522868"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["RS-2025-00573499"],"award-info":[{"award-number":["RS-2025-00573499"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["RS-2025-00522868"],"award-info":[{"award-number":["RS-2025-00522868"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"DOI":"10.1038\/s41598-025-98184-9","type":"journal-article","created":{"date-parts":[[2025,4,29]],"date-time":"2025-04-29T12:44:33Z","timestamp":1745930673000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["MoSeq based 3D behavioral profiling uncovers neuropathic behavior changes in diabetic mouse model"],"prefix":"10.1038","volume":"15","author":[{"given":"Akm","family":"Ashiquzzaman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eunbin","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brahnu Fentaw","family":"Znaub","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"An Nazmus","family":"Sakib","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geehoon","family":"Chung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang Seong","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young Ro","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyuk-Sang","family":"Kwon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Euiheon","family":"Chung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,4,29]]},"reference":[{"key":"98184_CR1","unstructured":"Federation, I.D. The IDF Diabetes Atlas (2021)."},{"key":"98184_CR2","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s11892-019-1212-8","volume":"19","author":"CW Hicks","year":"2019","unstructured":"Hicks, C. W. & Selvin, E. Epidemiology of peripheral neuropathy and lower extremity disease in diabetes. Curr. Diab.Rep. 19, 1\u20138 (2019).","journal-title":"Curr. Diab.Rep."},{"issue":"1","key":"98184_CR3","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1038\/s41572-019-0092-1","volume":"5","author":"EL Feldman","year":"2019","unstructured":"Feldman, E. L. et al. Diabetic neuropathy. Nat. Rev. Dis. Primers 5(1), 41 (2019).","journal-title":"Nat. Rev. Dis. Primers"},{"key":"98184_CR4","doi-asserted-by":"publisher","first-page":"738","DOI":"10.12688\/f1000research.7898.1","volume":"5","author":"K Juster-Switlyk","year":"2016","unstructured":"Juster-Switlyk, K. & Smith, A. G. Updates in diabetic peripheral neuropathy. F1000Research 5, 738 (2016).","journal-title":"F1000Research"},{"key":"98184_CR5","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1002\/dmrr.2239","volume":"28","author":"S Tesfaye","year":"2012","unstructured":"Tesfaye, S. & Selvarajah, D. Advances in the epidemiology, pathogenesis and management of diabetic peripheral neuropathy. Diabetes Metab. Res. Rev. 28, 8\u201314 (2012).","journal-title":"Diabetes Metab. Res. Rev."},{"issue":"3","key":"98184_CR6","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1093\/ilar\/ilt052","volume":"54","author":"PD O'Brien","year":"2014","unstructured":"O\u2019Brien, P. D., Sakowski, S. A. & Feldman, E. L. Mouse models of diabetic neuropathy. ILAR J. 54(3), 259\u2013272 (2014).","journal-title":"ILAR J."},{"issue":"8","key":"98184_CR7","doi-asserted-by":"publisher","DOI":"10.1002\/jbt.22508","volume":"34","author":"OM Abo-Salem","year":"2020","unstructured":"Abo-Salem, O. M. et al. Beneficial effects of (\u2212)-epigallocatechin-3-O-gallate on diabetic peripheral neuropathy in the rat model. J. Biochem. Mol. Toxicol. 34(8), e22508 (2020).","journal-title":"J. Biochem. Mol. Toxicol."},{"issue":"9","key":"98184_CR8","doi-asserted-by":"publisher","first-page":"15347","DOI":"10.1002\/jcb.28802","volume":"120","author":"G Guo","year":"2019","unstructured":"Guo, G. et al. Microarray analyses of lncRNAs and mRNAs expression profiling associated with diabetic peripheral neuropathy in rats. J. Cell Biochem. 120(9), 15347\u201315359 (2019).","journal-title":"J. Cell Biochem."},{"issue":"10","key":"98184_CR9","doi-asserted-by":"publisher","first-page":"11364","DOI":"10.1096\/fj.201900538R","volume":"33","author":"D Impellizzeri","year":"2019","unstructured":"Impellizzeri, D. et al. The neuroprotective effects of micronized PEA (PEA-m) formulation on diabetic peripheral neuropathy in mice. FASEB J. 33(10), 11364\u201311380 (2019).","journal-title":"FASEB J."},{"issue":"41","key":"98184_CR10","doi-asserted-by":"publisher","first-page":"19773","DOI":"10.1039\/D2NJ02823A","volume":"46","author":"GT Voss","year":"2022","unstructured":"Voss, G. T. et al. Contribution of antioxidant action of 7-chloro-4-(phenylselanyl) quinoline to treat streptozotocin-induced diabetic neuropathy in mice. New J. Chem. 46(41), 19773\u201319784 (2022).","journal-title":"New J. Chem."},{"key":"98184_CR11","doi-asserted-by":"publisher","DOI":"10.1155\/2011\/976948","volume":"2011","author":"N Zangiabadi","year":"2011","unstructured":"Zangiabadi, N. et al. Date fruit extract is a neuroprotective agent in diabetic peripheral neuropathy in streptozotocin-induced diabetic rats: a multimodal analysis. Oxid. Med. Cell Longev. 2011, 976948 (2011).","journal-title":"Oxid. Med. Cell Longev."},{"issue":"6","key":"98184_CR12","first-page":"PI43","volume":"11","author":"J Petrofsky","year":"2005","unstructured":"Petrofsky, J. et al. Gait characteristics in patients with type 2 diabetes; improvement after administration of rosiglitazone. Med. Sci. Monit. 11(6), PI43\u2013PI51 (2005).","journal-title":"Med. Sci. Monit."},{"issue":"6","key":"98184_CR13","doi-asserted-by":"publisher","first-page":"761","DOI":"10.1093\/ageing\/afw140","volume":"45","author":"Y Yang","year":"2016","unstructured":"Yang, Y. et al. Diabetes mellitus and risk of falls in older adults: a systematic review and meta-analysis. Age Ageing 45(6), 761\u2013767 (2016).","journal-title":"Age Ageing"},{"issue":"8","key":"98184_CR14","doi-asserted-by":"publisher","first-page":"687","DOI":"10.1016\/j.clinbiomech.2009.05.003","volume":"24","author":"I Sacco","year":"2009","unstructured":"Sacco, I. et al. Role of ankle mobility in foot rollover during gait in individuals with diabetic neuropathy. Clin. Biomech. (Bristol) 24(8), 687\u2013692 (2009).","journal-title":"Clin. Biomech. (Bristol)"},{"issue":"4","key":"98184_CR15","doi-asserted-by":"publisher","first-page":"570","DOI":"10.1016\/j.gaitpost.2014.06.018","volume":"40","author":"IC Sacco","year":"2014","unstructured":"Sacco, I. C. et al. Abnormalities of plantar pressure distribution in early, intermediate, and late stages of diabetic neuropathy. Gait Posture 40(4), 570\u2013574 (2014).","journal-title":"Gait Posture"},{"issue":"1","key":"98184_CR16","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s40064-016-3405-9","volume":"5","author":"A Hazari","year":"2016","unstructured":"Hazari, A. et al. Kinetics and kinematics of diabetic foot in type 2 diabetes mellitus with and without peripheral neuropathy: A systematic review and meta-analysis. Springerplus 5(1), 1\u201319 (2016).","journal-title":"Springerplus"},{"issue":"2","key":"98184_CR17","doi-asserted-by":"publisher","first-page":"298","DOI":"10.1002\/mus.23792","volume":"48","author":"MD Allen","year":"2013","unstructured":"Allen, M. D. et al. Motor unit loss and weakness in association with diabetic neuropathy in humans. Muscle Nerve 48(2), 298\u2013300 (2013).","journal-title":"Muscle Nerve"},{"issue":"4","key":"98184_CR18","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1111\/j.1600-0404.1999.tb00383.x","volume":"100","author":"H Andersen","year":"1999","unstructured":"Andersen, H. Motor function in diabetic neuropathy. Acta Neurol. Scand. 100(4), 211\u2013220 (1999).","journal-title":"Acta Neurol. Scand."},{"issue":"7","key":"98184_CR19","doi-asserted-by":"publisher","first-page":"2615","DOI":"10.1007\/s11011-022-01060-y","volume":"37","author":"M Dastgheib","year":"2022","unstructured":"Dastgheib, M. et al. Rolipram and pentoxifylline combination ameliorates experimental diabetic neuropathy through inhibition of oxidative stress and inflammatory pathways in the dorsal root ganglion neurons. Metab. Brain Dis. 37(7), 2615\u20132627 (2022).","journal-title":"Metab. Brain Dis."},{"key":"98184_CR20","unstructured":"Elgendy, A., & Abbas, A. (2020). Effect of heat Shock protein 90 Inhibition on Peripheral Neuropathy In Rats with Streptozocin-Induced Diabetes. Unpublished manuscript. https:\/\/www.researchgate.net\/profile\/Ahmed-Elgendy-11\/publication\/339988212_Effect_Of_heat_Shock_protein_90_Inhibition_On_Peripheral_Neuropathy_In_Rats_With_Streptozocin-Induced_Diabetes\/links\/5e713e81a6fdcc37caf30e31\/Effect-Of-heat-Shock-protein-90-Inhibition-On-Peripheral-Neuropathy-In-Rats-With-Streptozocin-Induced-Diabetes.pdf"},{"issue":"7","key":"98184_CR21","doi-asserted-by":"publisher","first-page":"1478","DOI":"10.1016\/j.pnpbp.2007.06.028","volume":"31","author":"R Fachinetto","year":"2007","unstructured":"Fachinetto, R. et al. Valeriana officinalis does not alter the orofacial dyskinesia induced by haloperidol in rats: role of dopamine transporter. Prog. Neuropsychopharmacol. Biol. Psychiatry 31(7), 1478\u20131486 (2007).","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"issue":"2","key":"98184_CR22","doi-asserted-by":"publisher","first-page":"425","DOI":"10.1006\/exnr.2000.7574","volume":"167","author":"A Pertovaara","year":"2001","unstructured":"Pertovaara, A. et al. Pain behavior and response properties of spinal dorsal horn neurons following experimental diabetic neuropathy in the rat: modulation by nitecapone, a COMT inhibitor with antioxidant properties. Exp. Neurol. 167(2), 425\u2013434 (2001).","journal-title":"Exp. Neurol."},{"key":"98184_CR23","doi-asserted-by":"publisher","first-page":"468","DOI":"10.1016\/j.biopha.2017.02.027","volume":"89","author":"V Solmaz","year":"2017","unstructured":"Solmaz, V. et al. Neuroprotective effects of octreotide on diabetic neuropathy in rats. Biomed. Pharmacother. 89, 468\u2013472 (2017).","journal-title":"Biomed. Pharmacother."},{"key":"98184_CR24","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/721547","volume":"2014","author":"N Zangiabadi","year":"2014","unstructured":"Zangiabadi, N. et al. The effect of Angipars on diabetic neuropathy in STZ-induced diabetic male rats: A study on behavioral, electrophysiological, sciatic histological and ultrastructural indices. ScientificWorldJournal 2014, 721547 (2014).","journal-title":"ScientificWorldJournal"},{"issue":"2","key":"98184_CR25","doi-asserted-by":"publisher","first-page":"59","DOI":"10.3844\/ajptsp.2011.59.67","volume":"6","author":"N Zangiabadi","year":"2011","unstructured":"Zangiabadi, N. et al. Effects of melatonin in prevention of neuropathy in STZ-induced diabetic rats. Am. J. Pharmacol. Toxicol. 6(2), 59\u201367 (2011).","journal-title":"Am. J. Pharmacol. Toxicol."},{"issue":"4","key":"98184_CR26","doi-asserted-by":"publisher","first-page":"410","DOI":"10.1038\/nmeth.1924","volume":"9","author":"F De Chaumont","year":"2012","unstructured":"De Chaumont, F. et al. Computerized video analysis of social interactions in mice. Nat. Methods 9(4), 410\u2013417 (2012).","journal-title":"Nat. Methods"},{"issue":"1","key":"98184_CR27","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1038\/nmeth.2281","volume":"10","author":"M Kabra","year":"2013","unstructured":"Kabra, M. et al. JAABA: Interactive machine learning for automatic annotation of animal behavior. Nat Methods 10(1), 64\u201367 (2013).","journal-title":"Nat Methods"},{"issue":"5","key":"98184_CR28","doi-asserted-by":"publisher","first-page":"731","DOI":"10.1016\/S0031-9384(01)00530-3","volume":"73","author":"A Spink","year":"2001","unstructured":"Spink, A. et al. The EthoVision video tracking system\u2014A tool for behavioral phenotyping of transgenic mice. Physiol. Behav. 73(5), 731\u2013744 (2001).","journal-title":"Physiol. Behav."},{"key":"98184_CR29","doi-asserted-by":"crossref","unstructured":"Furman, B. L. Streptozotocin\u2010induced diabetic models in mice and rats. Curr. Protoc. Pharmacol. 70(1), 5.47. 1\u20135.47. 20 (2015).","DOI":"10.1002\/0471141755.ph0547s70"},{"issue":"6","key":"98184_CR30","doi-asserted-by":"publisher","first-page":"1167","DOI":"10.1248\/bpb.29.1167","volume":"29","author":"T Nakamura","year":"2006","unstructured":"Nakamura, T. et al. Establishment and pathophysiological characterization of type 2 diabetic mouse model produced by streptozotocin and nicotinamide. Biol. Pharm. Bull. 29(6), 1167\u20131174 (2006).","journal-title":"Biol. Pharm. Bull."},{"issue":"5","key":"98184_CR31","doi-asserted-by":"publisher","first-page":"1271","DOI":"10.1097\/00000542-200011000-00021","volume":"93","author":"NA Calcutt","year":"2000","unstructured":"Calcutt, N. A., Freshwater, J. D. & O\u2019Brien, J. S. Protection of sensory function and antihyperalgesic properties of a prosaposin-derived peptide in diabetic rats. Anesthesiology 93(5), 1271\u20131278 (2000).","journal-title":"Anesthesiology"},{"issue":"6","key":"98184_CR32","doi-asserted-by":"publisher","first-page":"1121","DOI":"10.1016\/j.neuron.2015.11.031","volume":"88","author":"AB Wiltschko","year":"2015","unstructured":"Wiltschko, A. B. et al. Mapping sub-second structure in mouse behavior. Neuron 88(6), 1121\u20131135 (2015).","journal-title":"Neuron"},{"key":"98184_CR33","doi-asserted-by":"crossref","unstructured":"Markowitz, J. E., et al. The striatum organizes 3D behavior via moment-to-moment action selection. Cell 174(1), 44\u201358. e17 (2018).","DOI":"10.1016\/j.cell.2018.04.019"},{"key":"98184_CR34","doi-asserted-by":"crossref","unstructured":"Lin, S. et al. Characterizing the structure of mouse behavior using Motion Sequencing. Nature Protocols, 19(11), 3242\u20133291 (2024).","DOI":"10.1038\/s41596-024-01015-w"},{"key":"98184_CR35","unstructured":"Wiltschko, A. B., et al. Revealing the structure of pharmacobehavioral space through motion sequencing. (1546\u20131726 (Electronic))."},{"key":"98184_CR36","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2019.172408","volume":"856","author":"FC Dias","year":"2019","unstructured":"Dias, F. C. et al. The selective TRPV4 channel antagonist HC-067047 attenuates mechanical allodynia in diabetic mice. Eur. J. Pharmacol. 856, 172408 (2019).","journal-title":"Eur. J. Pharmacol."},{"key":"98184_CR37","doi-asserted-by":"publisher","first-page":"697","DOI":"10.1007\/s00210-019-01626-1","volume":"392","author":"M Mbiantcha","year":"2019","unstructured":"Mbiantcha, M. et al. Antihypernociceptive and neuroprotective effects of Combretin A and Combretin B on streptozotocin-induced diabetic neuropathy in mice. Naunyn. Schmiedebergs Arch. Pharmacol. 392, 697\u2013713 (2019).","journal-title":"Naunyn. Schmiedebergs Arch. Pharmacol."},{"issue":"2","key":"98184_CR38","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1002\/jnr.24501","volume":"98","author":"P Medeiros","year":"2020","unstructured":"Medeiros, P. et al. Characterization of the sensory, affective, cognitive, biochemical, and neuronal alterations in a modified chronic constriction injury model of neuropathic pain in mice. J. Neurosci. Res. 98(2), 338\u2013352 (2020).","journal-title":"J. Neurosci. Res."},{"issue":"2","key":"98184_CR39","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1038\/nn.4199","volume":"19","author":"W Ren","year":"2016","unstructured":"Ren, W. et al. The indirect pathway of the nucleus accumbens shell amplifies neuropathic pain. Nat. Neurosci. 19(2), 220\u2013222 (2016).","journal-title":"Nat. Neurosci."},{"key":"98184_CR40","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s40064-015-1009-4","volume":"4","author":"S van der Wal","year":"2015","unstructured":"van der Wal, S. et al. Behavior of neuropathic pain in mice following chronic constriction injury comparing silk and catgut ligatures. Springerplus 4, 1\u20138 (2015).","journal-title":"Springerplus"},{"key":"98184_CR41","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1016\/j.neulet.2013.12.056","volume":"561","author":"H Bagriyanik","year":"2014","unstructured":"Bagriyanik, H. et al. The effects of resveratrol on chronic constriction injury of sciatic nerve in rats. Neurosci. Lett. 561, 123\u2013127 (2014).","journal-title":"Neurosci. Lett."},{"issue":"1","key":"98184_CR42","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1016\/j.jep.2013.10.068","volume":"151","author":"GS Ta\u00efwe","year":"2014","unstructured":"Ta\u00efwe, G. S. et al. Nauclea latifolia Smith (Rubiaceae) exerts antinociceptive effects in neuropathic pain induced by chronic constriction injury of the sciatic nerve. J. Ethnopharmacol. 151(1), 445\u2013451 (2014).","journal-title":"J. Ethnopharmacol."}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-98184-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-98184-9","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-98184-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,29]],"date-time":"2025-04-29T12:44:40Z","timestamp":1745930680000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41598-025-98184-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,29]]},"references-count":42,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["98184"],"URL":"https:\/\/doi.org\/10.1038\/s41598-025-98184-9","relation":{},"ISSN":["2045-2322"],"issn-type":[{"value":"2045-2322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,29]]},"assertion":[{"value":"4 December 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 April 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 April 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"15114"}}