{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T12:37:59Z","timestamp":1770813479241,"version":"3.50.1"},"reference-count":25,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T00:00:00Z","timestamp":1768780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T00:00:00Z","timestamp":1770681600000},"content-version":"vor","delay-in-days":22,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100001826","name":"ZonMw","doi-asserted-by":"publisher","award":["843004112"],"award-info":[{"award-number":["843004112"]}],"id":[{"id":"10.13039\/501100001826","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001826","name":"ZonMw","doi-asserted-by":"publisher","award":["843004112"],"award-info":[{"award-number":["843004112"]}],"id":[{"id":"10.13039\/501100001826","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001826","name":"ZonMw","doi-asserted-by":"publisher","award":["843004112"],"award-info":[{"award-number":["843004112"]}],"id":[{"id":"10.13039\/501100001826","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001826","name":"ZonMw","doi-asserted-by":"publisher","award":["843004112"],"award-info":[{"award-number":["843004112"]}],"id":[{"id":"10.13039\/501100001826","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    For patients who underwent hip hemiarthroplasty, usually due to a femoral neck fracture from a fall, subsequent falls can have life-threatening consequences. This study identified predictors for falling in patients from a clinical trial comparing the direct lateral and posterolateral approach. Patients were included if they participated in the APOLLO trial. This secondary analysis divided patients into \u2018fallers\u2019 during 6\u00a0months follow-up, \u2018non-fallers,\u2019 and \u2018unknown.\u2019 Two logistic regression analyses were conducted: one using variables collected pre-surgery and one using variables available at discharge. The outcome variable 'fallen within 6\u00a0months after hemiarthroplasty\u2019 was dichotomous. Among the patients with known fall status, 219 (48%) fell one or more times and 240 (52%) were non-fallers. Fall status was unknown for 384 (46%) of the 843 APOLLO trial participants. Falling was associated with five pre-surgery variables: impaired mobility, ADL difficulties, neurological and pulmonary comorbidities, and dementia. At discharge, falling was associated with impaired mobility, ADL difficulties, and in-hospital complications. The pre-surgery model had an R\n                    <jats:sup>2<\/jats:sup>\n                    of 0.217 and an Area Under the Curve (AUC) of 0.730 (95% CI 0.7\u20130.8), while the discharge model had an R\n                    <jats:sup>2<\/jats:sup>\n                    of 0.216 and an AUC of 0.709 (95% CI 0.7\u20130.8). Both models showed moderate predictive ability for falling. This study highlights the substantial incidence of falls after hemiarthroplasty for femoral neck fractures and identified predictors for falling within six months. The multidisciplinary team should prioritize fall prevention, and future research should validate prediction models and assess whether fall prevention strategies can effectively reduce falls.\n                  <\/jats:p>","DOI":"10.1038\/s41598-026-35974-9","type":"journal-article","created":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T18:54:30Z","timestamp":1768848870000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Predictors for falling within six months after surgery in patients with hemiarthroplasty after an acute femoral neck fracture"],"prefix":"10.1038","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1257-3012","authenticated-orcid":false,"given":"Ariena J.","family":"Rasker","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa","family":"Berghorst","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nienke W.","family":"Willigenburg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria C. J. M.","family":"Tol","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rudolf W.","family":"Poolman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanna C.","family":"Willems","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,1,19]]},"reference":[{"key":"35974_CR1","unstructured":"The World Health Organization (WHO). Falls: key facts. WHO http:\/\/www.who.int\/news-room\/fact-sheets\/detail\/falls (September 2024, last accessed)."},{"key":"35974_CR2","unstructured":"The World Health Organization (WHO). WHO Global Report on Falls Prevention in Older Age. WHO https:\/\/extranet.who.int\/agefriendlyworld\/wp-content\/uploads\/2014\/06\/WHo-Global-report-on-falls-prevention-in-older-age.pdf (3 September 2024, last accessed)."},{"key":"35974_CR3","doi-asserted-by":"publisher","first-page":"3507","DOI":"10.1590\/1413-81232018249.30512017","volume":"24","author":"AQ Souza","year":"2019","unstructured":"Souza, A. Q. et al. Incidence and predictive factors of falls in community-dwelling elderly: A longitudinal study. Cien. Saude Colet. 24, 3507\u20133516 (2019).","journal-title":"Cien. Saude Colet."},{"key":"35974_CR4","doi-asserted-by":"publisher","first-page":"e26492","DOI":"10.1097\/MD.0000000000026492","volume":"100","author":"WC Chen","year":"2021","unstructured":"Chen, W. C. et al. The relationship between falling and fear of falling among community-dwelling elderly. Medicine (Baltimore) 100, e26492. https:\/\/doi.org\/10.1097\/MD.0000000000026492 (2021).","journal-title":"Medicine (Baltimore)"},{"key":"35974_CR5","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1111\/psyg.12217","volume":"17","author":"T Gazibara","year":"2017","unstructured":"Gazibara, T. et al. Falls, risk factors and fear of falling among persons older than 65 years of age. Psychogeriatrics 17, 215\u2013223 (2017).","journal-title":"Psychogeriatrics"},{"key":"35974_CR6","doi-asserted-by":"publisher","first-page":"1627","DOI":"10.2147\/CLEP.S181138","volume":"10","author":"C Galet","year":"2018","unstructured":"Galet, C. et al. Fall injuries, associated deaths, and 30-day readmission for subsequent falls are increasing in the elderly US population: a query of the WHO mortality database and National Readmission Database from 2010 to 2014. Clin. Epidemiol. 10, 1627\u20131637 (2018).","journal-title":"Clin. Epidemiol."},{"key":"35974_CR7","doi-asserted-by":"publisher","first-page":"337","DOI":"10.3390\/jpm14040337","volume":"14","author":"MR Schene","year":"2024","unstructured":"Schene, M. R. et al. The \u201cCan Do, Do Do\u201d framework applied to assess the association between physical capacity, physical activity and prospective falls, subsequent fractures, and mortality in patients visiting the fracture liaison service. J. Pers. Med. 14, 337 (2024).","journal-title":"J. Pers. Med."},{"key":"35974_CR8","doi-asserted-by":"publisher","unstructured":"Schene, M. R., Wyers, C. E., Driessen, A. M. H. et al. Imminent fall risk after fracture. Age Ageing 52, afad201 (2023). https:\/\/doi.org\/10.1093\/ageing\/afad201","DOI":"10.1093\/ageing\/afad201"},{"key":"35974_CR9","doi-asserted-by":"publisher","first-page":"570","DOI":"10.1093\/ageing\/afp107","volume":"38","author":"RR Miller","year":"2009","unstructured":"Miller, R. R. et al. Repeat falls and the recovery of social participation in the year post-hip fracture. Age Ageing 38, 570\u2013575 (2009).","journal-title":"Age Ageing"},{"key":"35974_CR10","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1007\/s00391-003-0142-9","volume":"36","author":"K Pils","year":"2003","unstructured":"Pils, K. et al. Predictors of falls in elderly people during rehabilitation after hip fracture\u2014who is at risk of a second one?. Z. Gerontol. Geriatr. 36, 16\u201322 (2003).","journal-title":"Z. Gerontol. Geriatr."},{"key":"35974_CR11","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1097\/00003086-199304000-00022","volume":"289","author":"HM Schroder","year":"1993","unstructured":"Schroder, H. M., Petersen, K. K. & Erlandsen, M. Occurrence and incidence of the second hip fracture. Clin. Orthop. Relat. Res. 289, 166\u2013169 (1993).","journal-title":"Clin. Orthop. Relat. 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Association between incident falls and subsequent fractures in patients attending the fracture liaison service after an index fracture: a 3-year prospective observational cohort study. BMJ Open 12, e058983. https:\/\/doi.org\/10.1136\/bmjopen-2021-058983 (2022).","journal-title":"BMJ Open"},{"key":"35974_CR15","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2023.50765","volume":"7","author":"M Tol","year":"2024","unstructured":"Tol, M. et al. Posterolateral or direct lateral surgical approach for hemiarthroplasty after a hip fracture: a randomized clinical trial alongside a natural experiment. JAMA Netw. Open 7, e2350765. https:\/\/doi.org\/10.1001\/jamanetworkopen.2023.50765 (2024).","journal-title":"JAMA Netw. Open"},{"key":"35974_CR16","doi-asserted-by":"publisher","first-page":"493","DOI":"10.2190\/UURL-2RYU-WRYD-EY3K","volume":"6","author":"S Katz","year":"1976","unstructured":"Katz, S. & Akpom, C. A. A measure of primary sociobiological functions. Int. J. 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Approval was granted by the Medical research Ethics Committees United (MEC-U, NL63378.100.17) and the local institutional review boards of all 14 participating centers. Written informed consent was obtained from all participants in the APOLLO trial, including both the Randomized Controlled Trial (RCT) and the Natural Experiment (NE).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Informed consent to participate was obtained from all individual participants included in the study. The Participant Information Form explicitly stated that the study results would be published, and participants provided their consent accordingly.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate and publish"}}],"article-number":"5695"}}