{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T10:28:54Z","timestamp":1771324134732,"version":"3.50.1"},"reference-count":44,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T00:00:00Z","timestamp":1769731200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T00:00:00Z","timestamp":1771286400000},"content-version":"vor","delay-in-days":18,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"DOI":"10.13039\/501100004704","name":"National Research Council of Thailand","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004704","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"DOI":"10.1038\/s41598-026-36574-3","type":"journal-article","created":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T12:05:58Z","timestamp":1769774758000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Assessing willingness to pay for HLA-B*58:01 genetic testing before allopurinol initiation and its potential impact on future health policy, Thailand"],"prefix":"10.1038","volume":"16","author":[{"given":"Patapong","family":"Towiwat","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naruemon","family":"Bamrungsawad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bodin","family":"Buttham","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Athagran","family":"Nakham","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nilawan","family":"Upakdee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,1,30]]},"reference":[{"key":"36574_CR1","doi-asserted-by":"publisher","first-page":"23","DOI":"10.2147\/vhrm.S115080","volume":"13","author":"M Bove","year":"2017","unstructured":"Bove, M., Cicero, A. F., Veronesi, M. & Borghi, C. An evidence-based review on urate-lowering treatments: Implications for optimal treatment of chronic hyperuricemia. Vasc. Health Risk Manag. 13, 23\u201328. https:\/\/doi.org\/10.2147\/vhrm.S115080 (2017).","journal-title":"Vasc. Health Risk Manag."},{"key":"36574_CR2","doi-asserted-by":"publisher","first-page":"744","DOI":"10.1002\/acr.24180","volume":"72","author":"JD FitzGerald","year":"2020","unstructured":"FitzGerald, J. D. et al. 2020 American College of Rheumatology guideline for the management of gout. Arthritis Care Res. (Hoboken) 72, 744\u2013760. https:\/\/doi.org\/10.1002\/acr.24180 (2020).","journal-title":"Arthritis Care Res. (Hoboken)"},{"key":"36574_CR3","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1111\/1756-185x.14266","volume":"25","author":"JPP Lorenzo","year":"2022","unstructured":"Lorenzo, J. P. P. et al. 2021 Asia-Pacific League of Associations for Rheumatology clinical practice guideline for treatment of gout. Int. J. Rheum. Dis. 25, 7\u201320. https:\/\/doi.org\/10.1111\/1756-185x.14266 (2022).","journal-title":"Int. J. Rheum. Dis."},{"key":"36574_CR4","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1136\/annrheumdis-2016-209707","volume":"76","author":"P Richette","year":"2017","unstructured":"Richette, P. et al. 2016 updated EULAR evidence-based recommendations for the management of gout. Ann. Rheum. Dis. 76, 29\u201342. https:\/\/doi.org\/10.1136\/annrheumdis-2016-209707 (2017).","journal-title":"Ann. Rheum. Dis."},{"key":"36574_CR5","doi-asserted-by":"publisher","first-page":"925","DOI":"10.4065\/81.7.925","volume":"81","author":"CA Sarawate","year":"2006","unstructured":"Sarawate, C. A. et al. Gout medication treatment patterns and adherence to standards of care from a managed care perspective. Mayo Clin. Proc. 81, 925\u2013934. https:\/\/doi.org\/10.4065\/81.7.925 (2006).","journal-title":"Mayo Clin. Proc."},{"key":"36574_CR6","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1093\/rheumatology\/kes211","volume":"52","author":"LK Stamp","year":"2013","unstructured":"Stamp, L. K. & Chapman, P. T. Gout and its comorbidities: Implications for therapy. Rheumatology (Oxford) 52, 34\u201344. https:\/\/doi.org\/10.1093\/rheumatology\/kes211 (2013).","journal-title":"Rheumatology (Oxford)"},{"key":"36574_CR7","first-page":"1025","volume":"102","author":"P Chiowchanwisawakit","year":"2019","unstructured":"Chiowchanwisawakit, P., Katchamart, W. & Srinonprasert, V. Survey of hyperuricemia and gout management among Thai physicians. J. Med. Assoc. Thailand 102, 1025\u20131032 (2019).","journal-title":"J. Med. Assoc. Thailand"},{"key":"36574_CR8","doi-asserted-by":"publisher","DOI":"10.3390\/jpm11020071","author":"O Ikediobi","year":"2021","unstructured":"Ikediobi, O. & Schneider, J. A. Pharmacogenomics of allopurinol and sulfamethoxazole\/trimethoprim: Case series and review of the literature. J. Pers. Med. https:\/\/doi.org\/10.3390\/jpm11020071 (2021).","journal-title":"J. Pers. Med."},{"key":"36574_CR9","doi-asserted-by":"publisher","first-page":"1741","DOI":"10.2217\/pgs.11.131","volume":"12","author":"I Zineh","year":"2011","unstructured":"Zineh, I. et al. Allopurinol pharmacogenetics: Assessment of potential clinical usefulness. Pharmacogenomics 12, 1741\u20131749. https:\/\/doi.org\/10.2217\/pgs.11.131 (2011).","journal-title":"Pharmacogenomics"},{"key":"36574_CR10","doi-asserted-by":"publisher","first-page":"186","DOI":"10.3389\/fphar.2016.00186","volume":"7","author":"C Sukasem","year":"2016","unstructured":"Sukasem, C. et al. HLA-B (*) 58:01 for allopurinol-induced cutaneous adverse drug reactions: Implication for clinical interpretation in Thailand. Front. Pharmacol. 7, 186. https:\/\/doi.org\/10.3389\/fphar.2016.00186 (2016).","journal-title":"Front. Pharmacol."},{"key":"36574_CR11","doi-asserted-by":"publisher","first-page":"704","DOI":"10.1097\/FPC.0b013e328330a3b8","volume":"19","author":"W Tassaneeyakul","year":"2009","unstructured":"Tassaneeyakul, W. et al. Strong association between HLA-B*5801 and allopurinol-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in a Thai population. Pharmacogenet. Genomics 19, 704\u2013709. https:\/\/doi.org\/10.1097\/FPC.0b013e328330a3b8 (2009).","journal-title":"Pharmacogenet. Genomics"},{"key":"36574_CR12","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1111\/bjd.13688","volume":"173","author":"L Cheng","year":"2015","unstructured":"Cheng, L. et al. HLA-B*58:01 is strongly associated with allopurinol-induced severe cutaneous adverse reactions in Han Chinese patients: A multicentre retrospective case-control clinical study. Br. J. Dermatol. 173, 555\u2013558. https:\/\/doi.org\/10.1111\/bjd.13688 (2015).","journal-title":"Br. J. Dermatol."},{"key":"36574_CR13","doi-asserted-by":"publisher","first-page":"4134","DOI":"10.1073\/pnas.0409500102","volume":"102","author":"SI Hung","year":"2005","unstructured":"Hung, S. I. et al. HLA-B*5801 allele as a genetic marker for severe cutaneous adverse reactions caused by allopurinol. Proc. Natl. Acad. Sci. U. S. A. 102, 4134\u20134139. https:\/\/doi.org\/10.1073\/pnas.0409500102 (2005).","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"36574_CR14","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1097\/FPC.0b013e32834282b8","volume":"21","author":"HR Kang","year":"2011","unstructured":"Kang, H. R. et al. Positive and negative associations of HLA class I alleles with allopurinol-induced SCARs in Koreans. Pharmacogenet. Genomics 21, 303\u2013307. https:\/\/doi.org\/10.1097\/FPC.0b013e32834282b8 (2011).","journal-title":"Pharmacogenet. Genomics"},{"key":"36574_CR15","doi-asserted-by":"publisher","first-page":"303","DOI":"10.2217\/pgs-2021-0156","volume":"23","author":"TT Ha Pham","year":"2022","unstructured":"Ha Pham, T. T. et al. Allopurinol-induced severe cutaneous adverse reactions in Vietnamese: The role of HLA alleles and other risk factors. Pharmacogenomics 23, 303\u2013313. https:\/\/doi.org\/10.2217\/pgs-2021-0156 (2022).","journal-title":"Pharmacogenomics"},{"key":"36574_CR16","doi-asserted-by":"publisher","first-page":"1057","DOI":"10.1111\/1756-185x.13143","volume":"20","author":"KH Yu","year":"2017","unstructured":"Yu, K. H., Yu, C. Y. & Fang, Y. F. Diagnostic utility of HLA-B*5801 screening in severe allopurinol hypersensitivity syndrome: An updated systematic review and meta-analysis. Int. J. Rheum. Dis. 20, 1057\u20131071. https:\/\/doi.org\/10.1111\/1756-185x.13143 (2017).","journal-title":"Int. J. Rheum. Dis."},{"key":"36574_CR17","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1080\/14737167.2023.2167713","volume":"23","author":"O Ben-Aharon","year":"2023","unstructured":"Ben-Aharon, O., Iskrov, G., Sagy, I. & Greenberg, D. Willingness to pay for cancer prevention, screening, diagnosis, and treatment: A systematic review. Expert Rev. Pharmacoecon. Outcomes Res. 23, 281\u2013295. https:\/\/doi.org\/10.1080\/14737167.2023.2167713 (2023).","journal-title":"Expert Rev. Pharmacoecon. Outcomes Res."},{"key":"36574_CR18","doi-asserted-by":"publisher","first-page":"635","DOI":"10.2147\/ceor.S382735","volume":"14","author":"T Jantarakolica","year":"2022","unstructured":"Jantarakolica, T. et al. Willingness to pay and time trade-off in thai patients with port-wine stains. Clinicoecon. Outcomes Res. 14, 635\u2013642. https:\/\/doi.org\/10.2147\/ceor.S382735 (2022).","journal-title":"Clinicoecon. Outcomes Res."},{"key":"36574_CR19","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1016\/j.puhe.2023.08.022","volume":"224","author":"P Orellano","year":"2023","unstructured":"Orellano, P., Reynoso, J., Salom\u00f3n, O. D. & Vezzani, D. Dengue vaccine acceptance and willingness to pay: A systematic review and meta-analysis. Public Health 224, 74\u201381. https:\/\/doi.org\/10.1016\/j.puhe.2023.08.022 (2023).","journal-title":"Public Health"},{"key":"36574_CR20","doi-asserted-by":"publisher","first-page":"606","DOI":"10.1177\/0272989x08315252","volume":"28","author":"D Khanna","year":"2008","unstructured":"Khanna, D., Ahmed, M., Yontz, D., Ginsburg, S. S. & Tsevat, J. Willingness to pay for a cure in patients with chronic gout. Med. Decis. Mak. 28, 606\u2013613. https:\/\/doi.org\/10.1177\/0272989x08315252 (2008).","journal-title":"Med. Decis. Mak."},{"key":"36574_CR21","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1007\/s10067-022-06356-z","volume":"42","author":"YJ Li","year":"2023","unstructured":"Li, Y. J. et al. Comparative efficacy and safety of uricosuric agents in the treatment of gout or hyperuricemia: A systematic review and network meta-analysis. Clin. Rheumatol. 42, 215\u2013224. https:\/\/doi.org\/10.1007\/s10067-022-06356-z (2023).","journal-title":"Clin. Rheumatol."},{"key":"36574_CR22","doi-asserted-by":"publisher","first-page":"729","DOI":"10.1111\/jcpt.13156","volume":"45","author":"SS Sun","year":"2020","unstructured":"Sun, S. S., Zhang, D. H., Shi, Y., Lin, C. J. & Lin, J. Y. Efficacy and safety of urate-lowering treatments in patients with hyperuricemia: A comprehensive network meta-analysis of randomized controlled trials. J. Clin. Pharm. Ther. 45, 729\u2013742. https:\/\/doi.org\/10.1111\/jcpt.13156 (2020).","journal-title":"J. Clin. Pharm. Ther."},{"key":"36574_CR23","doi-asserted-by":"publisher","first-page":"e70093","DOI":"10.1002\/acr2.70093","volume":"7","author":"P Dilokthornsakul","year":"2025","unstructured":"Dilokthornsakul, P. et al. An updated economic evaluation of HLA-B*58:01 Genotype testing in gouty patients for preventing severe allopurinol hypersensitivity in Thailand. ACR Open Rheumatol. 7, e70093. https:\/\/doi.org\/10.1002\/acr2.70093 (2025).","journal-title":"ACR Open Rheumatol."},{"key":"36574_CR24","doi-asserted-by":"publisher","first-page":"914","DOI":"10.1016\/j.vaccine.2007.12.011","volume":"26","author":"R Palanca-Tan","year":"2008","unstructured":"Palanca-Tan, R. The demand for a dengue vaccine: A contingent valuation survey in Metro Manila. Vaccine 26, 914\u2013923. https:\/\/doi.org\/10.1016\/j.vaccine.2007.12.011 (2008).","journal-title":"Vaccine"},{"key":"36574_CR25","doi-asserted-by":"publisher","first-page":"786","DOI":"10.1080\/21645515.2016.1259045","volume":"13","author":"H Harapan","year":"2017","unstructured":"Harapan, H., Fajar, J. K., Sasmono, R. T. & Kuch, U. Dengue vaccine acceptance and willingness to pay. Hum. Vaccin. Immunother. 13, 786\u2013790. https:\/\/doi.org\/10.1080\/21645515.2016.1259045 (2017).","journal-title":"Hum. Vaccin. Immunother."},{"key":"36574_CR26","doi-asserted-by":"publisher","first-page":"e0003810","DOI":"10.1371\/journal.pntd.0003810","volume":"9","author":"JS Lee","year":"2015","unstructured":"Lee, J. S. et al. A multi-country study of the household willingness-to-pay for dengue vaccines: Household surveys in Vietnam, Thailand, and Colombia. PLoS Negl. Trop. Dis. 9, e0003810. https:\/\/doi.org\/10.1371\/journal.pntd.0003810 (2015).","journal-title":"PLoS Negl. Trop. Dis."},{"key":"36574_CR27","doi-asserted-by":"publisher","first-page":"12154","DOI":"10.1038\/s41598-023-39264-6","volume":"13","author":"P Luksameesate","year":"2023","unstructured":"Luksameesate, P., Tanavalee, A., Ngorsuraches, S. & Taychakhoonavudh, S. Using a discrete choice experiment to elicit patients\u2019 preferences and willingness-to-pay for knee osteoarthritis treatments in Thailand. Sci. Rep. 13, 12154. https:\/\/doi.org\/10.1038\/s41598-023-39264-6 (2023).","journal-title":"Sci. Rep."},{"key":"36574_CR28","doi-asserted-by":"publisher","first-page":"1727","DOI":"10.22034\/apjcp.2018.19.6.1727","volume":"19","author":"U Saengow","year":"2018","unstructured":"Saengow, U., Birch, S., Geater, A. & Chongsuwiwatvong, V. Willingness to pay for colorectal cancer screening and effect of copayment in Southern Thailand. Asian Pac. J. Cancer Prev. 19, 1727\u20131734. https:\/\/doi.org\/10.22034\/apjcp.2018.19.6.1727 (2018).","journal-title":"Asian Pac. J. Cancer Prev."},{"key":"36574_CR29","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines10040627","author":"K Mueangpoon","year":"2022","unstructured":"Mueangpoon, K. et al. Self-reported COVID-19 vaccine hesitancy and willingness to pay: A cross-sectional survey in Thailand. Vaccines (Basel). https:\/\/doi.org\/10.3390\/vaccines10040627 (2022).","journal-title":"Vaccines (Basel)."},{"key":"36574_CR30","doi-asserted-by":"publisher","first-page":"1843","DOI":"10.1016\/s0140-6736(21)00569-9","volume":"397","author":"N Dalbeth","year":"2021","unstructured":"Dalbeth, N., Gosling, A. L., Gaffo, A. & Abhishek, A. Gout. Lancet 397, 1843\u20131855. https:\/\/doi.org\/10.1016\/s0140-6736(21)00569-9 (2021).","journal-title":"Lancet"},{"key":"36574_CR31","doi-asserted-by":"publisher","DOI":"10.31436\/imjm.v20i3.1953","author":"A An","year":"2021","unstructured":"An, A. et al. Willingness to pay for cancer genetic testing in a tertiary healthcare centre. IIUM Med. J. Malays. https:\/\/doi.org\/10.31436\/imjm.v20i3.1953 (2021).","journal-title":"IIUM Med. J. Malays."},{"key":"36574_CR32","doi-asserted-by":"publisher","first-page":"e016662","DOI":"10.1136\/bmjopen-2017-016662","volume":"8","author":"J Blouin-Bougie","year":"2018","unstructured":"Blouin-Bougie, J., Amara, N., Bouchard, K., Simard, J. & Dorval, M. Disentangling the determinants of interest and willingness-to-pay for breast cancer susceptibility testing in the general population: A cross-sectional Web-based survey among women of Qu\u00e9bec (Canada). BMJ Open 8, e016662. https:\/\/doi.org\/10.1136\/bmjopen-2017-016662 (2018).","journal-title":"BMJ Open"},{"key":"36574_CR33","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1186\/s12886-024-03808-9","volume":"24","author":"P Tantichariyangkul","year":"2024","unstructured":"Tantichariyangkul, P. et al. The health-related quality of life in patients with dry eye syndrome: A cross-sectional study in Thailand. BMC Ophthalmol. 24, 539. https:\/\/doi.org\/10.1186\/s12886-024-03808-9 (2024).","journal-title":"BMC Ophthalmol."},{"key":"36574_CR34","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1080\/14740338.2019.1594771","volume":"18","author":"L Strilchuk","year":"2019","unstructured":"Strilchuk, L., Fogacci, F. & Cicero, A. F. Safety and tolerability of available urate-lowering drugs: A critical review. Expert Opin. Drug Saf. 18, 261\u2013271. https:\/\/doi.org\/10.1080\/14740338.2019.1594771 (2019).","journal-title":"Expert Opin. Drug Saf."},{"key":"36574_CR35","doi-asserted-by":"publisher","first-page":"S11","DOI":"10.1016\/j.semarthrit.2020.04.008","volume":"50","author":"JA Singh","year":"2020","unstructured":"Singh, J. A. & Gaffo, A. Gout epidemiology and comorbidities. Semin. Arthritis Rheum. 50, S11\u2013S16. https:\/\/doi.org\/10.1016\/j.semarthrit.2020.04.008 (2020).","journal-title":"Semin. Arthritis Rheum."},{"key":"36574_CR36","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1186\/s13075-015-0610-9","volume":"17","author":"MJ Roughley","year":"2015","unstructured":"Roughley, M. J., Belcher, J., Mallen, C. D. & Roddy, E. Gout and risk of chronic kidney disease and nephrolithiasis: Meta-analysis of observational studies. Arthritis Res. Ther. 17, 90. https:\/\/doi.org\/10.1186\/s13075-015-0610-9 (2015).","journal-title":"Arthritis Res. Ther."},{"key":"36574_CR37","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1186\/s12877-015-0137-6","volume":"15","author":"R Worasathit","year":"2015","unstructured":"Worasathit, R. et al. Health education and factors influencing acceptance of and willingness to pay for influenza vaccination among older adults. BMC Geriatr. 15, 136. https:\/\/doi.org\/10.1186\/s12877-015-0137-6 (2015).","journal-title":"BMC Geriatr."},{"key":"36574_CR38","doi-asserted-by":"publisher","first-page":"412","DOI":"10.1177\/1403494812453884","volume":"40","author":"A Asgary","year":"2012","unstructured":"Asgary, A. Assessing households\u2019 willingness to pay for an immediate pandemic influenza vaccination programme. Scand. J. Public Health 40, 412\u2013417. https:\/\/doi.org\/10.1177\/1403494812453884 (2012).","journal-title":"Scand. J. Public Health"},{"key":"36574_CR39","doi-asserted-by":"publisher","first-page":"1717030","DOI":"10.1080\/20016689.2020.1717030","volume":"8","author":"JA McDougall","year":"2020","unstructured":"McDougall, J. A., Furnback, W. E., Wang, B. C. M. & Mahlich, J. Understanding the global measurement of willingness to pay in health. J. Mark. Access. Health Policy 8, 1717030. https:\/\/doi.org\/10.1080\/20016689.2020.1717030 (2020).","journal-title":"J. Mark. Access. Health Policy"},{"key":"36574_CR40","doi-asserted-by":"publisher","first-page":"1789","DOI":"10.1136\/annrheumdis-2015-208237","volume":"74","author":"T Neogi","year":"2015","unstructured":"Neogi, T. et al. 2015 Gout classification criteria: An American College of Rheumatology\/European League Against Rheumatism collaborative initiative. Ann. Rheum. Dis. 74, 1789\u20131798. https:\/\/doi.org\/10.1136\/annrheumdis-2015-208237 (2015).","journal-title":"Ann. Rheum. Dis."},{"key":"36574_CR41","doi-asserted-by":"publisher","first-page":"604","DOI":"10.7326\/0003-4819-150-9-200905050-00006","volume":"150","author":"AS Levey","year":"2009","unstructured":"Levey, A. S. et al. A new equation to estimate glomerular filtration rate. Ann. Intern. Med. 150, 604\u2013612. https:\/\/doi.org\/10.7326\/0003-4819-150-9-200905050-00006 (2009).","journal-title":"Ann. Intern. Med."},{"key":"36574_CR42","doi-asserted-by":"publisher","first-page":"90","DOI":"10.3399\/bjgp20X708053","volume":"70","author":"NR Jones","year":"2020","unstructured":"Jones, N. R., McCormack, T., Constanti, M. & McManus, R. J. Diagnosis and management of hypertension in adults: NICE guideline update 2019. Br. J. Gen. Pract. 70, 90\u201391. https:\/\/doi.org\/10.3399\/bjgp20X708053 (2020).","journal-title":"Br. J. Gen. Pract."},{"key":"36574_CR43","doi-asserted-by":"publisher","first-page":"611","DOI":"10.1210\/endrev\/bnab037","volume":"43","author":"AJ Berberich","year":"2022","unstructured":"Berberich, A. J. & Hegele, R. A. A modern approach to dyslipidemia. Endocr. Rev. 43, 611\u2013653. https:\/\/doi.org\/10.1210\/endrev\/bnab037 (2022).","journal-title":"Endocr. Rev."},{"key":"36574_CR44","doi-asserted-by":"publisher","first-page":"148","DOI":"10.4103\/picr.PICR_87_17","volume":"8","author":"P Ranganathan","year":"2017","unstructured":"Ranganathan, P., Pramesh, C. S. & Aggarwal, R. Common pitfalls in statistical analysis: Logistic regression. Perspect. Clin. Res. 8, 148\u2013151. https:\/\/doi.org\/10.4103\/picr.PICR_87_17 (2017).","journal-title":"Perspect. Clin. Res."}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41598-026-36574-3","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-026-36574-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-026-36574-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T09:34:01Z","timestamp":1771320841000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41598-026-36574-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,30]]},"references-count":44,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["36574"],"URL":"https:\/\/doi.org\/10.1038\/s41598-026-36574-3","relation":{},"ISSN":["2045-2322"],"issn-type":[{"value":"2045-2322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,30]]},"assertion":[{"value":"17 November 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 January 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 January 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Informed consent was attained from all patients with gout.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"The study protocol was approved by the Institutional Review Board and Ethics Committee, in accordance with the Declaration of Helsinki of Naresuan University Hospital (IRB No. P3-0041\/2565).","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical considerations"}},{"value":"This work was presented in a poster form at \u201cThe International Conference of Chinese Rheumatologists (ICCR 2024)\u201d in Hong Kong and was published in Journal of Clinical Rheumatology and Immunology 2024 Vol. 24 Issue supp 01 Pages 154.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical responsibilities of authors"}}],"article-number":"6763"}}