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Little is known about risk and protective factors along the continuum. In the current study, we assessed ninety-four university students (36 individuals indicated suicidal ideation and 33 reported self-harm) for suicidality, depression, entrapment, defeat, hopelessness, mindfulness, self-compassion, and implicit associations with death\/suicide. We used regression models and moderation analyses to test if mindfulness, self-compassion, and implicit association with death\/suicide related to suicidal ideation, self-harm, entrapment, or moderated the hypothesized continuum from entrapment to suicidal ideation and from entrapment to self-harm. Analyses were corrected for the severity of depressive symptomatology. Results indicated that lower self-compassion and weaker implicit associations with death\/suicide were statistically associated with self-harm, but not suicidal ideation. Mindfulness is trend-wise associated with entrapment and moderated the relation between entrapment and suicidal ideation. Self-compassion nor implicit associations with death\/suicide moderated the relation between entrapment and suicidal ideation. Hence, lower self-compassion and weaker implicit associations with death\/suicide seem directly related to suicide risk behaviour, whereas mindfulness appears to negatively (i.e., suggestive of a protective role) relate to psychological risk-states earlier in the continuum. Therefore, self-compassion and mindfulness seem promising prevention targets for suicide risk in young adults.<\/jats:p>","DOI":"10.1038\/s41598-026-37127-4","type":"journal-article","created":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T18:44:59Z","timestamp":1769712299000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Psychological and cognitive-emotional moderators of suicidal ideation and self-harm in young adults"],"prefix":"10.1038","volume":"16","author":[{"given":"Justine","family":"Dickhoff","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenrui","family":"Deng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9","family":"Aleman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vera","family":"de Vries","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esther Marije","family":"Opmeer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-Jos\u00e9","family":"van Tol","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,1,29]]},"reference":[{"key":"37127_CR1","unstructured":"World Health Organization. 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