{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T00:13:07Z","timestamp":1793059987324,"version":"4.5.0"},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T00:00:00Z","timestamp":1770595200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2026,3,2]],"date-time":"2026-03-02T00:00:00Z","timestamp":1772409600000},"content-version":"vor","delay-in-days":21,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"DOI":"10.13039\/501100025469","name":"Research Institute for Health Sciences, Chiang Mai University","doi-asserted-by":"publisher","award":["8393 (25)\/3450"],"award-info":[{"award-number":["8393 (25)\/3450"]}],"id":[{"id":"10.13039\/501100025469","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100025469","name":"Research Institute for Health Sciences, Chiang Mai University","doi-asserted-by":"publisher","award":["039\/2568"],"award-info":[{"award-number":["039\/2568"]}],"id":[{"id":"10.13039\/501100025469","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"DOI":"10.1038\/s41598-026-39147-6","type":"journal-article","created":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T12:56:28Z","timestamp":1770641788000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Seroprevalence and determinants of hepatitis E virus infection among people living with HIV in Chiang Mai, Thailand: a cross-sectional analysis"],"prefix":"10.1038","volume":"16","author":[{"given":"Ruba","family":"Chakma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kanyaruck","family":"Jindaphun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad","family":"Umer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Likhitphorn","family":"Khamai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natthapol","family":"Kosashunhanan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kriengkrai","family":"Srithanaviboonchai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Woottichai","family":"Khamduang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sayamon","family":"Hongjaisee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,2,9]]},"reference":[{"key":"39147_CR1","unstructured":"World Health Organization, Hepatitis, E. & Organization, G. World Health (2025). (accessed 20 October 2025);  https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/hepatitis-e"},{"key":"39147_CR2","doi-asserted-by":"publisher","first-page":"1580863","DOI":"10.3389\/fpubh.2025.1580863","volume":"13","author":"L Zhang","year":"2025","unstructured":"Zhang, L. et al. Update on the global burden of acute viral hepatitis in 2021: addressing health inequalities. Front. Public. Health. 13, 1580863. https:\/\/doi.org\/10.3389\/fpubh.2025.1580863 (2025).","journal-title":"Front. Public. Health"},{"key":"39147_CR3","doi-asserted-by":"publisher","first-page":"e158","DOI":"10.1017\/S0950268820001429","volume":"148","author":"H Bi","year":"2020","unstructured":"Bi, H., Yang, R., Wu, C. & Xia, J. Hepatitis E virus and blood transfusion safety. Epidemiol. Infect. 148, e158. https:\/\/doi.org\/10.1017\/S0950268820001429 (2020).","journal-title":"Epidemiol. Infect."},{"key":"39147_CR4","doi-asserted-by":"publisher","DOI":"10.1002\/rmv.1937","author":"DW Al-Sadeq","year":"2017","unstructured":"Al-Sadeq, D. W., Majdalawieh, A. F. & Nasrallah, G. K. Seroprevalence and incidence of hepatitis E virus among blood donors: A review. Rev. Med. Virol. https:\/\/doi.org\/10.1002\/rmv.1937 (2017).","journal-title":"Rev. Med. Virol."},{"key":"39147_CR5","doi-asserted-by":"publisher","first-page":"1067","DOI":"10.1111\/jvh.12730","volume":"24","author":"S Sharma","year":"2017","unstructured":"Sharma, S. et al. Risk factors for vertical transmission of hepatitis E virus infection. J. Viral Hepat. 24, 1067\u20131075. https:\/\/doi.org\/10.1111\/jvh.12730 (2017).","journal-title":"J. Viral Hepat."},{"key":"39147_CR6","doi-asserted-by":"publisher","first-page":"117","DOI":"10.14218\/JCTH.2014.00006","volume":"2","author":"S El Zaki","year":"2014","unstructured":"El Zaki, S., Razek, M. E., El Razek, H. M. & M. M. & Maternal-Fetal hepatitis E transmission: is it underestimated? J. Clin. Transl Hepatol. 2, 117\u2013123. https:\/\/doi.org\/10.14218\/JCTH.2014.00006 (2014).","journal-title":"J. Clin. Transl Hepatol."},{"key":"39147_CR7","doi-asserted-by":"publisher","unstructured":"Yadav, S., Shirodker, S. & Kshirsagar, S. Maternal and fetal outcome in pregnancy with hepatitis E virus infection. Int. J. Reprod. Contracept. Obstet. Gynecol. 3482\u20133490. https:\/\/doi.org\/10.18203\/2320-1770.ijrcog20163428 (2016).","DOI":"10.18203\/2320-1770.ijrcog20163428"},{"key":"39147_CR8","doi-asserted-by":"publisher","first-page":"2811","DOI":"10.2169\/internalmedicine.55.7025","volume":"55","author":"M Miyoshi","year":"2016","unstructured":"Miyoshi, M. et al. Chronic hepatitis E infection in a persistently immunosuppressed patient unable to be eliminated after ribavirin therapy. Intern. Med. 55, 2811\u20132817. https:\/\/doi.org\/10.2169\/internalmedicine.55.7025 (2016).","journal-title":"Intern. Med."},{"key":"39147_CR9","doi-asserted-by":"publisher","first-page":"1143","DOI":"10.1038\/s41598-018-37328-6","volume":"9","author":"S Vazquez-Moron","year":"2019","unstructured":"Vazquez-Moron, S. et al. Prevalence of hepatitis E infection in HIV\/HCV-coinfected patients in Spain (2012\u20132014). Sci. Rep. 9, 1143. https:\/\/doi.org\/10.1038\/s41598-018-37328-6 (2019).","journal-title":"Sci. Rep."},{"key":"39147_CR10","doi-asserted-by":"publisher","first-page":"1931","DOI":"10.1097\/qad.0000000000000378","volume":"28","author":"JA Pineda","year":"2014","unstructured":"Pineda, J. A. et al. Incidence and natural history of hepatitis E virus coinfection among HIV-infected patients. Aids 28, 1931\u20131937. https:\/\/doi.org\/10.1097\/qad.0000000000000378 (2014).","journal-title":"Aids"},{"key":"39147_CR11","doi-asserted-by":"publisher","first-page":"1425","DOI":"10.3389\/fmicb.2019.01425","volume":"10","author":"A Rivero-Juarez","year":"2019","unstructured":"Rivero-Juarez, A., Lopez-Lopez, P., Frias, M. & Rivero, A. Hepatitis E infection in HIV-infected patients. Front. Microbiol. 10, 1425 (2019).","journal-title":"Front. Microbiol."},{"key":"39147_CR12","doi-asserted-by":"publisher","first-page":"102329","DOI":"10.1016\/j.bjid.2022.102329","volume":"26","author":"E Golkocheva-Markova","year":"2022","unstructured":"Golkocheva-Markova, E. et al. Assessment of hepatitis E seropositivity among HIV-infected patients in Bulgaria. Brazilian J. Infect. Dis. 26, 102329 (2022).","journal-title":"Brazilian J. Infect. Dis."},{"key":"39147_CR13","doi-asserted-by":"publisher","first-page":"ofy307","DOI":"10.1093\/ofid\/ofy307","volume":"5","author":"OA Demi Sibiro","year":"2018","unstructured":"Demi Sibiro, O. A., Manirakiza, A. & Komas, N. P. Seroprevalence of hepatitis E virus infection among people living with HIV in the central African Republic. Open. Forum Infect. Dis. 5, ofy307. https:\/\/doi.org\/10.1093\/ofid\/ofy307 (2018).","journal-title":"Open. Forum Infect. Dis."},{"key":"39147_CR14","doi-asserted-by":"publisher","first-page":"1531","DOI":"10.3201\/eid2009.140418","volume":"20","author":"S Gonwong","year":"2014","unstructured":"Gonwong, S. et al. Pork consumption and Seroprevalence of hepatitis E virus,Thailand, 2007\u20132008. Emerg. Infect. Dis. 20, 1531\u20131534. https:\/\/doi.org\/10.3201\/eid2009.140418 (2014).","journal-title":"Emerg. Infect. Dis."},{"key":"39147_CR15","doi-asserted-by":"publisher","first-page":"302","DOI":"10.1089\/vim.2018.0146","volume":"32","author":"S Jupattanasin","year":"2019","unstructured":"Jupattanasin, S. et al. A nationwide survey of the Seroprevalence of hepatitis E virus infections among blood donors in Thailand. Viral Immunol. 32, 302\u2013307. https:\/\/doi.org\/10.1089\/vim.2018.0146 (2019).","journal-title":"Viral Immunol."},{"key":"39147_CR16","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1186\/s12879-024-09349-2","volume":"24","author":"UK Mirzaev","year":"2024","unstructured":"Mirzaev, U. K. et al. Systematic review and meta-analysis of hepatitis E Seroprevalence in Southeast asia: a comprehensive assessment of epidemiological patterns. BMC Infect. Dis. 24, 525. https:\/\/doi.org\/10.1186\/s12879-024-09349-2 (2024).","journal-title":"BMC Infect. Dis."},{"key":"39147_CR17","doi-asserted-by":"publisher","first-page":"e0126184","DOI":"10.1371\/journal.pone.0126184","volume":"10","author":"P Sa-nguanmoo","year":"2015","unstructured":"Sa-nguanmoo, P. et al. Swine is a possible source of hepatitis E virus infection by comparative study of hepatitis A and E Seroprevalence in Thailand. PLoS One. 10, e0126184. https:\/\/doi.org\/10.1371\/journal.pone.0126184 (2015).","journal-title":"PLoS One"},{"key":"39147_CR18","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1186\/s12985-021-01616-x","volume":"18","author":"A Boonyai","year":"2021","unstructured":"Boonyai, A. et al. Prevalence and clinical correlation of hepatitis E virus antibody in the patients\u2019 serum samples from a tertiary care hospital in Thailand during 2015\u20132018. Virol. J. 18, 145. https:\/\/doi.org\/10.1186\/s12985-021-01616-x (2021).","journal-title":"Virol. J."},{"key":"39147_CR19","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1080\/00034983.1996.11813043","volume":"90","author":"Y Poovorawan","year":"1996","unstructured":"Poovorawan, Y., Theamboonlers, A., Chumdermpadetsuk, S. & Komolmit, P. Prevalence of hepatitis E virus infection in Thailand. Ann. Trop. Med. Parasitol. 90, 189\u2013196. https:\/\/doi.org\/10.1080\/00034983.1996.11813043 (1996).","journal-title":"Ann. Trop. Med. Parasitol."},{"key":"39147_CR20","doi-asserted-by":"publisher","first-page":"1425","DOI":"10.3389\/fmicb.2019.01425","volume":"10","author":"A Rivero-Juarez","year":"2019","unstructured":"Rivero-Juarez, A., Lopez-Lopez, P., Frias, M. & Rivero, A. Hepatitis E infection in HIV-Infected patients. Front. Microbiol. 10, 1425. https:\/\/doi.org\/10.3389\/fmicb.2019.01425 (2019).","journal-title":"Front. Microbiol."},{"key":"39147_CR21","doi-asserted-by":"publisher","first-page":"102329","DOI":"10.1016\/j.bjid.2022.102329","volume":"26","author":"E Golkocheva-Markova","year":"2022","unstructured":"Golkocheva-Markova, E. et al. Assessment of hepatitis E seropositivity among HIV-infected patients in Bulgaria. Braz J. Infect. Dis. 26, 102329. https:\/\/doi.org\/10.1016\/j.bjid.2022.102329 (2022).","journal-title":"Braz J. Infect. Dis."},{"key":"39147_CR22","doi-asserted-by":"publisher","DOI":"10.7754\/Clin.Lab.2019.191122","author":"S Oz","year":"2020","unstructured":"Oz, S., Altindis, M., Toptan, H., Koroglu, M. & Karabay, O. Investigation of hepatitis E Seroprevalence in HIV positive patients by a novel enzyme linked fluorescent assay test. Clin. Lab. https:\/\/doi.org\/10.7754\/Clin.Lab.2019.191122 (2020).","journal-title":"Clin. Lab."},{"key":"39147_CR23","doi-asserted-by":"publisher","first-page":"1989","DOI":"10.1002\/jmv.25545","volume":"91","author":"AF Modiyinji","year":"2019","unstructured":"Modiyinji, A. F., Amougou-Atsama, M., Monamele, C. G., Nola, M. & Njouom, R. Seroprevalence of hepatitis E virus antibodies in different human populations of Cameroon. J. Med. Virol. 91, 1989\u20131994. https:\/\/doi.org\/10.1002\/jmv.25545 (2019).","journal-title":"J. Med. Virol."},{"key":"39147_CR24","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1016\/j.jcv.2013.05.004","volume":"58","author":"T Feldt","year":"2013","unstructured":"Feldt, T. et al. Hepatitis E virus infections in HIV-infected patients in Ghana and Cameroon. J. Clin. Virol. 58, 18\u201323 (2013).","journal-title":"J. Clin. Virol."},{"key":"39147_CR25","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1016\/j.jcv.2013.05.004","volume":"58","author":"T Feldt","year":"2013","unstructured":"Feldt, T. et al. Hepatitis E virus infections in HIV-infected patients in Ghana and Cameroon. J. Clin. Virol. 58, 18\u201323. https:\/\/doi.org\/10.1016\/j.jcv.2013.05.004 (2013).","journal-title":"J. Clin. Virol."},{"key":"39147_CR26","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1016\/j.actatropica.2018.09.026","volume":"189","author":"LA Bezerra","year":"2019","unstructured":"Bezerra, L. A. et al. Risk analysis and Seroprevalence of HEV in people living with HIV\/AIDS in Brazil. Acta Trop. 189, 65\u201368. https:\/\/doi.org\/10.1016\/j.actatropica.2018.09.026 (2019).","journal-title":"Acta Trop."},{"key":"39147_CR27","doi-asserted-by":"publisher","first-page":"1517","DOI":"10.1002\/jmv.24214","volume":"87","author":"M Politou","year":"2015","unstructured":"Politou, M. et al. Seroprevalence of hepatitis E in HIV infected patients in Greece. J. Med. Virol. 87, 1517\u20131520. https:\/\/doi.org\/10.1002\/jmv.24214 (2015).","journal-title":"J. Med. Virol."},{"key":"39147_CR28","doi-asserted-by":"publisher","first-page":"408","DOI":"10.1016\/j.jcv.2014.05.009","volume":"60","author":"RJ Hassing","year":"2014","unstructured":"Hassing, R. J. et al. Hepatitis E prevalence among HIV infected patients with elevated liver enzymes in the Netherlands. J. Clin. Virol. 60, 408\u2013410. https:\/\/doi.org\/10.1016\/j.jcv.2014.05.009 (2014).","journal-title":"J. Clin. Virol."},{"key":"39147_CR29","first-page":"103","volume":"7","author":"H Joulaei","year":"2015","unstructured":"Joulaei, H., Rudgari, O., Motazedian, N. & Gorji-Makhsous, S. Hepatitis E virus Seroprevalence in HIV positive individuals in Shiraz, Southern Iran. Iran. J. Microbiol. 7, 103\u2013108 (2015).","journal-title":"Iran. J. Microbiol."},{"key":"39147_CR30","doi-asserted-by":"publisher","first-page":"310","DOI":"10.1016\/j.jinf.2016.12.004","volume":"74","author":"F Abravanel","year":"2017","unstructured":"Abravanel, F. et al. HEV infection in French HIV-infected patients. J. Infect. 74, 310\u2013313. https:\/\/doi.org\/10.1016\/j.jinf.2016.12.004 (2017).","journal-title":"J. Infect."},{"key":"39147_CR31","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1016\/j.ijid.2017.05.014","volume":"61","author":"M Bura","year":"2017","unstructured":"Bura, M., \u0141agiedo, M., Michalak, M., Sikora, J. & Mozer-Lisewska, I. Hepatitis E virus IgG Seroprevalence in HIV patients and blood donors, west-central Poland. Int. J. Infect. Dis. 61, 20\u201322. https:\/\/doi.org\/10.1016\/j.ijid.2017.05.014 (2017).","journal-title":"Int. J. Infect. Dis."},{"key":"39147_CR32","doi-asserted-by":"crossref","unstructured":"Yaqoobi, H., \u00d6nlen, Y., \u00c7abalak, M. & Demir, T. Investigation of hepatitis E virus Seroprevalence and chronic hepatitis E infection in HIV-Positive patients. (2024).","DOI":"10.4274\/vhd.galenos.2024.2024-1-2"},{"key":"39147_CR33","doi-asserted-by":"publisher","first-page":"986","DOI":"10.1186\/s12879-025-11382-8","volume":"25","author":"C Wagle","year":"2025","unstructured":"Wagle, C. et al. HEV Seroprevalence and associated risk factors among HIV-positive individuals in post-earthquake kathmandu: a 2016 cross-sectional study. BMC Infect. Dis. 25, 986. https:\/\/doi.org\/10.1186\/s12879-025-11382-8 (2025).","journal-title":"BMC Infect. Dis."},{"key":"39147_CR34","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1186\/s12985-017-0899-x","volume":"14","author":"A Shrestha","year":"2017","unstructured":"Shrestha, A. et al. Prevalence and risk of hepatitis E virus infection in the HIV population of Nepal. Virol. J. 14, 228. https:\/\/doi.org\/10.1186\/s12985-017-0899-x (2017).","journal-title":"Virol. J."},{"key":"39147_CR35","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1186\/s12879-022-07127-6","volume":"22","author":"H Bagulo","year":"2022","unstructured":"Bagulo, H., Majekodunmi, A. O., Welburn, S. C. & Bimi, L. Hepatitis E Seroprevalence and risk factors in humans and pig in Ghana. BMC Infect. Dis. 22, 132. https:\/\/doi.org\/10.1186\/s12879-022-07127-6 (2022).","journal-title":"BMC Infect. Dis."},{"key":"39147_CR36","doi-asserted-by":"publisher","first-page":"e0269253","DOI":"10.1371\/journal.pone.0269253","volume":"17","author":"NV Fern\u00e1ndez Villalobos","year":"2022","unstructured":"Fern\u00e1ndez Villalobos, N. V. et al. Seroprevalence of hepatitis E virus infection in the americas: estimates from a systematic review and meta-analysis. PLoS One. 17, e0269253. https:\/\/doi.org\/10.1371\/journal.pone.0269253 (2022).","journal-title":"PLoS One"},{"key":"39147_CR37","doi-asserted-by":"publisher","unstructured":"Sridhar, S. et al. Risk of Hepatitis E among persons who inject drugs in Hong Kong: A qualitative and quantitative serological analysis. Microorganisms  https:\/\/doi.org\/10.3390\/microorganisms8050675 (2020).","DOI":"10.3390\/microorganisms8050675"},{"key":"39147_CR38","doi-asserted-by":"publisher","first-page":"e74","DOI":"10.1111\/jvh.12233","volume":"21","author":"KE Sherman","year":"2014","unstructured":"Sherman, K. E., Terrault, N., Barin, B., Rouster, S. D. & Shata, M. T. Hepatitis E infection in HIV-infected liver and kidney transplant candidates. J. Viral Hepat. 21, e74\u201377. https:\/\/doi.org\/10.1111\/jvh.12233 (2014).","journal-title":"J. Viral Hepat."},{"key":"39147_CR39","doi-asserted-by":"publisher","first-page":"e103028","DOI":"10.1371\/journal.pone.0103028","volume":"9","author":"M Riveiro-Barciela","year":"2014","unstructured":"Riveiro-Barciela, M. et al. Cirrhosis, liver transplantation and HIV infection are risk factors associated with hepatitis E virus infection. PLoS One. 9, e103028. https:\/\/doi.org\/10.1371\/journal.pone.0103028 (2014).","journal-title":"PLoS One"},{"key":"39147_CR40","doi-asserted-by":"publisher","first-page":"15","DOI":"10.4137\/vrt.S15422","volume":"5","author":"SA Junaid","year":"2014","unstructured":"Junaid, S. A., Agina, S. E. & Abubakar, K. A. Epidemiology and associated risk factors of hepatitis e virus infection in plateau state, Nigeria. Virol. (Auckl). 5, 15\u201326. https:\/\/doi.org\/10.4137\/vrt.S15422 (2014).","journal-title":"Virol. (Auckl)"},{"key":"39147_CR41","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1177\/1545109712453939","volume":"11","author":"L Sereno","year":"2012","unstructured":"Sereno, L. et al. Epidemiology, responses, and way forward: the silent epidemic of viral hepatitis and HIV coinfection in Vietnam. J. Int. Assoc. Physicians AIDS Care (Chic). 11, 311\u2013320. https:\/\/doi.org\/10.1177\/1545109712453939 (2012).","journal-title":"J. Int. Assoc. Physicians AIDS Care (Chic)"},{"key":"39147_CR42","doi-asserted-by":"publisher","first-page":"61","DOI":"10.3126\/ajms.v14i4.50299","volume":"14","author":"RH Pradhan","year":"2024","unstructured":"Pradhan, R. H., Khandelwal, K., Bamboriya, V., Marothi, B. L. & Saxena, Y. A cross-sectional study on co-infection of hepatitis B and hepatitis C among people living with HIV\/AIDS from a tertiary care hospital of central India. Asian J. Med. Sci. 14, 61\u201367 (2024).","journal-title":"Asian J. Med. Sci."}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41598-026-39147-6","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-026-39147-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-026-39147-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T00:02:27Z","timestamp":1772496147000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41598-026-39147-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,9]]},"references-count":42,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["39147"],"URL":"https:\/\/doi.org\/10.1038\/s41598-026-39147-6","relation":{},"ISSN":["2045-2322"],"issn-type":[{"value":"2045-2322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,9]]},"assertion":[{"value":"6 November 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 February 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 February 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"7853"}}