{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T14:09:30Z","timestamp":1775743770196,"version":"3.50.1"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T00:00:00Z","timestamp":1772496000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T00:00:00Z","timestamp":1775692800000},"content-version":"vor","delay-in-days":37,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"DOI":"10.1038\/s41598-026-40767-1","type":"journal-article","created":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T16:03:44Z","timestamp":1772553824000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Association between the geriatric nutritional risk index and all-cause mortality in patients with acute pancreatitis in the intensive care unit: a retrospective cohort study"],"prefix":"10.1038","volume":"16","author":[{"given":"Chenghua","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chaowei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiuyun","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xin","family":"Tu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiuping","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kang","family":"Zou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yulong","family":"Luo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,3,3]]},"reference":[{"key":"40767_CR1","doi-asserted-by":"crossref","unstructured":"Sellers, Z. M., Barakat, M. T. & Abu-El-Haija, M. A practical approach to management of acute pancreatitis: similarities and dissimilarities of disease in children and adults. J Clin. Med. 10(12). (2021).","DOI":"10.3390\/jcm10122545"},{"key":"40767_CR2","doi-asserted-by":"publisher","first-page":"1515418","DOI":"10.3389\/fmed.2025.1515418","volume":"12","author":"GG Gainollina","year":"2025","unstructured":"Gainollina, G. G. et al. Global research trends in necrotizing pancreatitis: a bibliometric analysis from 2013 to 2024. Front. Med. (Lausanne). 12, 1515418 (2025).","journal-title":"Front. Med. (Lausanne)"},{"key":"40767_CR3","doi-asserted-by":"publisher","first-page":"762","DOI":"10.3389\/fimmu.2017.00762","volume":"8","author":"LL Pan","year":"2017","unstructured":"Pan, L. L., Li, J., Shamoon, M., Bhatia, M. & Sun, J. Recent Advances on Nutrition in Treatment of Acute Pancreatitis. Front. Immunol. 8, 762 (2017).","journal-title":"Front. Immunol."},{"issue":"1","key":"40767_CR4","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1016\/S2468-1253(16)30004-8","volume":"1","author":"AY Xiao","year":"2016","unstructured":"Xiao, A. Y. et al. Global incidence and mortality of pancreatic diseases: a systematic review, meta-analysis, and meta-regression of population-based cohort studies. Lancet Gastroenterol. Hepatol. 1 (1), 45\u201355 (2016).","journal-title":"Lancet Gastroenterol. Hepatol."},{"issue":"8","key":"40767_CR5","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1038\/s41575-019-0158-2","volume":"16","author":"PJ Lee","year":"2019","unstructured":"Lee, P. J. & Papachristou, G. I. New insights into acute pancreatitis. Nat. Rev. Gastroenterol. Hepatol. 16 (8), 479\u2013496 (2019).","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"issue":"8","key":"40767_CR6","doi-asserted-by":"publisher","first-page":"1244","DOI":"10.1097\/MPA.0000000000000200","volume":"43","author":"S Hamada","year":"2014","unstructured":"Hamada, S. et al. Nationwide epidemiological survey of acute pancreatitis in Japan. Pancreas 43 (8), 1244\u20131248 (2014).","journal-title":"Pancreas"},{"issue":"1","key":"40767_CR7","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1038\/s41430-018-0149-3","volume":"73","author":"S Khalatbari-Soltani","year":"2019","unstructured":"Khalatbari-Soltani, S., de Mestral, C., Waeber, G. & Marques-Vidal, P. Large regional disparities in prevalence, management and reimbursement of hospital undernutrition. Eur. J. Clin. Nutr. 73 (1), 121\u2013131 (2019).","journal-title":"Eur. J. Clin. Nutr."},{"issue":"1","key":"40767_CR8","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1002\/jpen.2267","volume":"46","author":"C Compher","year":"2022","unstructured":"Compher, C. et al. Guidelines for the provision of nutrition support therapy in the adult critically ill patient: The American Society for Parenteral and Enteral Nutrition. JPEN J. Parenter. Enter. Nutr. 46 (1), 12\u201341 (2022).","journal-title":"JPEN J. Parenter. Enter. Nutr."},{"issue":"6","key":"40767_CR9","doi-asserted-by":"publisher","first-page":"R268","DOI":"10.1186\/cc10546","volume":"15","author":"DK Heyland","year":"2011","unstructured":"Heyland, D. K., Dhaliwal, R., Jiang, X. & Day, A. G. Identifying critically ill patients who benefit the most from nutrition therapy: the development and initial validation of a novel risk assessment tool. Crit. Care. 15 (6), R268 (2011).","journal-title":"Crit. Care"},{"issue":"5","key":"40767_CR10","doi-asserted-by":"publisher","first-page":"744","DOI":"10.1177\/0148607115625638","volume":"41","author":"CCH Lew","year":"2017","unstructured":"Lew, C. C. H. et al. Association Between Malnutrition and Clinical Outcomes in the Intensive Care Unit: A Systematic Review [Formula: see text]. JPEN J. Parenter. Enter. Nutr. 41 (5), 744\u2013758 (2017).","journal-title":"JPEN J. Parenter. Enter. Nutr."},{"issue":"4","key":"40767_CR11","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1016\/S0261-5614(03)00098-0","volume":"22","author":"J Kondrup","year":"2003","unstructured":"Kondrup, J. et al. ESPEN guidelines for nutrition screening 2002. Clin. Nutr. 22 (4), 415\u2013421 (2003).","journal-title":"Clin. Nutr."},{"issue":"25","key":"40767_CR12","doi-asserted-by":"publisher","first-page":"e38672","DOI":"10.1097\/MD.0000000000038672","volume":"103","author":"K Kollu","year":"2024","unstructured":"Kollu, K. et al. Comparison of nutritional risk indices (PNI, GNRI, mNUTRIC) and HALP score in predicting adverse clinical outcomes in older patients staying in an intensive care unit. Med. (Baltim). 103 (25), e38672 (2024).","journal-title":"Med. (Baltim)."},{"issue":"5","key":"40767_CR13","doi-asserted-by":"publisher","first-page":"843","DOI":"10.1016\/j.clnu.2013.01.007","volume":"32","author":"JS Lee","year":"2013","unstructured":"Lee, J. S., Choi, H. S., Ko, Y. G. & Yun, D. H. Performance of the Geriatric Nutritional Risk Index in predicting 28-day hospital mortality in older adult patients with sepsis. Clin. Nutr. 32 (5), 843\u2013848 (2013).","journal-title":"Clin. Nutr."},{"issue":"1","key":"40767_CR14","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1186\/s12871-024-02689-1","volume":"24","author":"D Zhao","year":"2024","unstructured":"Zhao, D., Zhou, D., Li, T., Wang, C. & Fei, S. The relationship between Geriatric Nutritional Risk Index (GNRI) and in-hospital mortality in critically ill patients with Acute Kidney Injury (AKI). BMC Anesthesiol. 24 (1), 313 (2024).","journal-title":"BMC Anesthesiol"},{"issue":"Suppl 3","key":"40767_CR15","first-page":"S51","volume":"94","author":"S Turcan","year":"2021","unstructured":"Turcan, S. & Tofan-Scutaru, L. Nutrition therapy in acute and chronic pancreatitis. Med. Pharm. Rep. 94 (Suppl 3), S51\u2013S5 (2021).","journal-title":"Med. Pharm. Rep."},{"issue":"2","key":"40767_CR16","doi-asserted-by":"publisher","first-page":"395","DOI":"10.1016\/j.clnu.2023.12.019","volume":"43","author":"M Arvanitakis","year":"2024","unstructured":"Arvanitakis, M. et al. ESPEN practical guideline on clinical nutrition in acute and chronic pancreatitis. Clin. Nutr. 43 (2), 395\u2013412 (2024).","journal-title":"Clin. Nutr."},{"issue":"4","key":"40767_CR17","doi-asserted-by":"publisher","first-page":"777","DOI":"10.1093\/ajcn\/82.4.777","volume":"82","author":"O Bouillanne","year":"2005","unstructured":"Bouillanne, O. et al. Geriatric Nutritional Risk Index: a new index for evaluating at-risk elderly medical patients. Am. J. Clin. Nutr. 82 (4), 777\u2013783 (2005).","journal-title":"Am. J. Clin. Nutr."},{"key":"40767_CR18","doi-asserted-by":"publisher","first-page":"846659","DOI":"10.3389\/fnut.2022.846659","volume":"9","author":"H Fan","year":"2022","unstructured":"Fan, H. et al. Association of Four Nutritional Scores With All-Cause and Cardiovascular Mortality in the General Population. Front. Nutr. 9, 846659 (2022).","journal-title":"Front. Nutr."},{"key":"40767_CR19","doi-asserted-by":"publisher","first-page":"1258037","DOI":"10.3389\/fmed.2023.1258037","volume":"10","author":"L Li","year":"2023","unstructured":"Li, L., Lu, X., Qin, S. & Huang, D. Association between geriatric nutritional risk index and 28 days mortality in elderly patients with sepsis: a retrospective cohort study. Front. Med. (Lausanne). 10, 1258037 (2023).","journal-title":"Front. Med. (Lausanne)"},{"key":"40767_CR20","doi-asserted-by":"crossref","unstructured":"Wang, C. et al. Association between geriatric nutritional risk index and the progression of chronic critical illness and short-term prognosis in sepsis patients. Shock (2025).","DOI":"10.1097\/SHK.0000000000002711"},{"key":"40767_CR21","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1016\/j.sopen.2024.03.012","volume":"19","author":"A Metri","year":"2024","unstructured":"Metri, A., Bush, N. & Singh, V. K. Predicting the severity of acute pancreatitis: Current approaches and future directions. Surg. Open. Sci. 19, 109\u2013117 (2024).","journal-title":"Surg. Open. Sci."},{"issue":"6","key":"40767_CR22","doi-asserted-by":"publisher","first-page":"432","DOI":"10.1111\/j.0894-0959.2004.17603.x","volume":"17","author":"BR Don","year":"2004","unstructured":"Don, B. R. & Kaysen, G. Serum albumin: relationship to inflammation and nutrition. Semin Dial. 17 (6), 432\u2013437 (2004).","journal-title":"Semin Dial"},{"issue":"1","key":"40767_CR23","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1016\/j.clnu.2016.09.004","volume":"36","author":"T Cederholm","year":"2017","unstructured":"Cederholm, T. et al. ESPEN guidelines on definitions and terminology of clinical nutrition. Clin. Nutr. 36 (1), 49\u201364 (2017).","journal-title":"Clin. Nutr."},{"issue":"6","key":"40767_CR24","doi-asserted-by":"publisher","first-page":"678","DOI":"10.1016\/j.jcmgh.2015.07.006","volume":"1","author":"OA Mareninova","year":"2015","unstructured":"Mareninova, O. A. et al. Lysosome associated membrane proteins maintain pancreatic acinar cell homeostasis: LAMP-2 deficient mice develop pancreatitis. Cell. Mol. Gastroenterol. Hepatol. 1 (6), 678\u2013694 (2015).","journal-title":"Cell. Mol. Gastroenterol. Hepatol."},{"issue":"5","key":"40767_CR25","doi-asserted-by":"publisher","first-page":"459","DOI":"10.2746\/042516409X385823","volume":"41","author":"LL Southwood","year":"2009","unstructured":"Southwood, L. L., Dolente, B. A., Lindborg, S., Russell, G. & Boston, R. Short-term outcome of equine emergency admissions at a university referral hospital. Equine Vet. J. 41 (5), 459\u2013464 (2009).","journal-title":"Equine Vet. J."},{"key":"40767_CR26","doi-asserted-by":"publisher","first-page":"1077414","DOI":"10.3389\/fimmu.2022.1077414","volume":"13","author":"K Venkatesh","year":"2022","unstructured":"Venkatesh, K., Glenn, H., Delaney, A., Andersen, C. R. & Sasson, S. C. Fire in the belly: A scoping review of the immunopathological mechanisms of acute pancreatitis. Front. Immunol. 13, 1077414 (2022).","journal-title":"Front. Immunol."},{"issue":"3","key":"40767_CR27","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1038\/s41575-018-0087-5","volume":"16","author":"MS Petrov","year":"2019","unstructured":"Petrov, M. S. & Yadav, D. Global epidemiology and holistic prevention of pancreatitis. Nat. Rev. Gastroenterol. Hepatol. 16 (3), 175\u2013184 (2019).","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"issue":"4","key":"40767_CR28","doi-asserted-by":"publisher","first-page":"540","DOI":"10.1002\/ncp.10242","volume":"34","author":"K Allen","year":"2019","unstructured":"Allen, K. & Hoffman, L. Enteral Nutrition in the Mechanically Ventilated Patient. Nutr. Clin. Pract. 34 (4), 540\u2013557 (2019).","journal-title":"Nutr. Clin. Pract."},{"key":"40767_CR29","doi-asserted-by":"publisher","first-page":"1101555","DOI":"10.3389\/fnut.2023.1101555","volume":"10","author":"D Chen","year":"2023","unstructured":"Chen, D. et al. Prognostic performance of the NRS2002, NUTRIC, and modified NUTRIC to identify high nutritional risk in severe acute pancreatitis patients. Front. Nutr. 10, 1101555 (2023).","journal-title":"Front. Nutr."}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41598-026-40767-1","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-026-40767-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-026-40767-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T13:23:19Z","timestamp":1775740999000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41598-026-40767-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,3]]},"references-count":29,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["40767"],"URL":"https:\/\/doi.org\/10.1038\/s41598-026-40767-1","relation":{},"ISSN":["2045-2322"],"issn-type":[{"value":"2045-2322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,3]]},"assertion":[{"value":"30 December 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 February 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 March 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"11882"}}