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This study investigates the long-term effects of individualized colored spectacle filters on visual comfort and function in patients with Age-related Macular Degeneration and Leber Hereditary Optic Neuropathy. Patients were fitted with individualized precision tint spectacles tailored to improve vision comfort for one year. The study involved a comprehensive evaluation of visual acuity, contrast sensitivity, and photophobia symptoms alongside qualitative feedback from patient interviews. Results indicate significant improvements in subjective visual comfort and function, with a notable reduction in photophobia symptoms among patients with Leber Hereditary Optic Neuropathy. Colored filters, particularly those in the blue-green spectrum, were preferred by most patients and had a positive impact on comfort. Statistical analysis revealed trends in color preferences and subjective enhancements in visual function, underscoring the potential benefits of comfort-tint filters and the importance of personalized treatment approaches. The findings suggest that individualized colored spectacle filters can be valuable in enhancing visual comfort and function for patients with central visual field defects. This study shows the importance of integrating visual comfort considerations into clinical practice for a comprehensive approach to patient care.<\/jats:p>","DOI":"10.1038\/s41598-026-45302-w","type":"journal-article","created":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T08:26:45Z","timestamp":1774513605000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Impact of individualized colored spectacle filters on photophobia and visual comfort in central visual field defect patients: a one-year study"],"prefix":"10.1038","volume":"16","author":[{"given":"Margarita","family":"Krasniakova","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tony","family":"Pansell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00f6rgen","family":"Gustafsson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,3,26]]},"reference":[{"key":"45302_CR1","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1080\/09273970802020243","volume":"16","author":"S Abdi","year":"2008","unstructured":"Abdi, S., Lennerstrand, G., Pansell, T. & Rydberg, A. 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