{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T10:49:14Z","timestamp":1774954154802,"version":"3.50.1"},"reference-count":23,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T00:00:00Z","timestamp":1774828800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T00:00:00Z","timestamp":1774915200000},"content-version":"vor","delay-in-days":1,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"name":"the Institutional research project of 984 hospital of Joint Support Force"},{"name":"\u201cWild Goose Formation\u201d Project of Joint Support Force"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"DOI":"10.1038\/s41598-026-45504-2","type":"journal-article","created":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T06:45:59Z","timestamp":1774853159000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Nighttime intensive care unit admission increased 30-day mortality in sepsis patients: a retrospective propensity-score matched analysis based on MIMIC-IV database"],"prefix":"10.1038","volume":"16","author":[{"given":"Cheng","family":"Peng","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tianqi","family":"Shen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jie","family":"Peng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xueming","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jie","family":"Yan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yongjun","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haimiao","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fan","family":"Gao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,3,30]]},"reference":[{"key":"45504_CR1","doi-asserted-by":"publisher","first-page":"581","DOI":"10.1016\/S1473-3099(15)70112-X","volume":"15","author":"J Cohen","year":"2015","unstructured":"Cohen, J. et al. Sepsis: A roadmap for future research. Lancet Infect. Dis. 15, 581\u2013614 (2015).","journal-title":"Lancet Infect. Dis."},{"key":"45504_CR2","doi-asserted-by":"publisher","first-page":"1264","DOI":"10.1164\/rccm.201204-0713OC","volume":"186","author":"CW Seymour","year":"2012","unstructured":"Seymour, C. W. et al. Severe sepsis in pre-hospital emergency care: Analysis of incidence, care, and outcome. Am. J. Respir. Crit. Care Med. 186, 1264\u20131271 (2012).","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"45504_CR3","doi-asserted-by":"publisher","first-page":"735","DOI":"10.1016\/S0140-6736(00)02634-9","volume":"356","author":"MC Blunt","year":"2000","unstructured":"Blunt, M. C. & Burchett, K. R. Out-of-hours consultant cover and case-mix-adjusted mortality in intensive care. Lancet 356, 735\u2013736 (2000).","journal-title":"Lancet"},{"key":"45504_CR4","unstructured":"Pronovost, P. J. et al. Physician staffing patterns and clinical outcomes in critically ill patients."},{"key":"45504_CR5","doi-asserted-by":"publisher","first-page":"287","DOI":"10.5694\/j.1326-5377.2011.tb02976.x","volume":"194","author":"D Bhonagiri","year":"2011","unstructured":"Bhonagiri, D., Pilcher, D. V. & Bailey, M. J. Increased mortality associated with after\u2010hours and weekend admission to the intensive care unit: a retrospective analysis. Med. J. Aust. 194, 287\u2013292 (2011).","journal-title":"Med. J. Aust."},{"key":"45504_CR6","doi-asserted-by":"publisher","first-page":"344","DOI":"10.1016\/j.jclinepi.2007.11.008","volume":"61","author":"E von Elm","year":"2008","unstructured":"von Elm, E. et al. The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: Guidelines for reporting observational studies. J. Clin. Epidemiol. 61, 344\u2013349 (2008).","journal-title":"J. Clin. Epidemiol."},{"key":"45504_CR7","doi-asserted-by":"publisher","first-page":"801","DOI":"10.1001\/jama.2016.0287","volume":"315","author":"M Singer","year":"2016","unstructured":"Singer, M. et al. The third international consensus definitions for sepsis and septic shock (Sepsis-3). JAMA 315, 801 (2016).","journal-title":"JAMA"},{"key":"45504_CR8","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-023-04655-8","volume":"27","author":"R Sonneville","year":"2023","unstructured":"Sonneville, R. et al. The spectrum of sepsis-associated encephalopathy: A clinical perspective. Crit. Care 27, 386 (2023).","journal-title":"Crit. Care"},{"key":"45504_CR9","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2017-017046","volume":"7","author":"T Iba","year":"2017","unstructured":"Iba, T., Nisio, M. D., Levy, J. H., Kitamura, N. & Thachil, J. New criteria for sepsis-induced coagulopathy (SIC) following the revised sepsis definition: A retrospective analysis of a nationwide survey. BMJ Open 7, e017046 (2017).","journal-title":"BMJ Open"},{"key":"45504_CR10","doi-asserted-by":"publisher","first-page":"1289194","DOI":"10.3389\/fmed.2023.1289194","volume":"10","author":"B Sun","year":"2023","unstructured":"Sun, B. et al. Acute lung injury caused by sepsis: How does it happen?. Front. Med. 10, 1289194 (2023).","journal-title":"Front. Med."},{"key":"45504_CR11","doi-asserted-by":"publisher","first-page":"858","DOI":"10.1097\/01.CCM.0000055378.31408.26","volume":"31","author":"IJ Morales","year":"2003","unstructured":"Morales, I. J., Peters, S. G. & Afessa, B. Hospital mortality rate and length of stay in patients admitted at night to the intensive care unit*. Crit. Care Med. 31, 858\u2013863 (2003).","journal-title":"Crit. Care Med."},{"key":"45504_CR12","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6963-11-321","volume":"11","author":"KB Laupland","year":"2011","unstructured":"Laupland, K. B. et al. Mortality associated with timing of admission to and discharge from ICU: A retrospective cohort study. BMC Health Serv. Res. 11, 321 (2011).","journal-title":"BMC Health Serv. Res."},{"key":"45504_CR13","doi-asserted-by":"publisher","DOI":"10.2147\/IJGM.S54536","author":"M Elkhayari","year":"2014","unstructured":"Elkhayari, M., Dilai, O., Ziadi, A., Hachimi, A. & Samkaoui, A. Outcome of patients admitted during off hours in Moroccan intensive care unit. Int. J. Gen. Med. https:\/\/doi.org\/10.2147\/IJGM.S54536 (2014).","journal-title":"Int. J. Gen. Med."},{"key":"45504_CR14","doi-asserted-by":"publisher","first-page":"390","DOI":"10.1186\/s13054-016-1569-x","volume":"20","author":"S Yang","year":"2016","unstructured":"Yang, S., Wang, Z., Liu, Z., Wang, J. & Ma, L. Association between time of discharge from ICU and hospital mortality: A systematic review and meta-analysis. Crit. Care 20, 390 (2016).","journal-title":"Crit. Care"},{"key":"45504_CR15","doi-asserted-by":"publisher","first-page":"395","DOI":"10.1016\/S0257-5655(07)70003-2","volume":"23","author":"C Sheu","year":"2007","unstructured":"Sheu, C. et al. Admission time and outcomes of patients in a medical intensive care unit. Kaohsiung J. Med. Sci. 23, 395\u2013404 (2007).","journal-title":"Kaohsiung J. Med. Sci."},{"key":"45504_CR16","doi-asserted-by":"publisher","first-page":"1765","DOI":"10.1007\/s00134-010-1918-1","volume":"36","author":"HAJM Kuijsten","year":"2010","unstructured":"Kuijsten, H. A. J. M. et al. Hospital mortality is associated with ICU admission time. Intensive Care Med. 36, 1765\u20131771 (2010).","journal-title":"Intensive Care Med."},{"key":"45504_CR17","doi-asserted-by":"publisher","first-page":"R230","DOI":"10.1186\/cc13053","volume":"17","author":"M-J Ju","year":"2013","unstructured":"Ju, M.-J. et al. Effect of admission time on mortality in an intensive care unit in Mainland China: A propensity score matching analysis. Crit. Care 17, R230 (2013).","journal-title":"Crit. Care"},{"key":"45504_CR18","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0168548","volume":"11","author":"V Brunot","year":"2016","unstructured":"Brunot, V. et al. Mortality associated with night and weekend admissions to ICU with on-site intensivist coverage: Results of a nine-year cohort study (2006\u20132014). PLoS ONE 11, e0168548 (2016).","journal-title":"PLoS ONE"},{"key":"45504_CR19","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1067\/mem.2001.111571","volume":"37","author":"G Kuhn","year":"2001","unstructured":"Kuhn, G. Circadian rhythm, shift work, and emergency medicine. Ann. Emerg. Med. 37, 88\u201398 (2001).","journal-title":"Ann. Emerg. Med."},{"key":"45504_CR20","doi-asserted-by":"publisher","first-page":"386","DOI":"10.1186\/s13054-023-04655-8","volume":"27","author":"R Sonneville","year":"2023","unstructured":"Sonneville, R. et al. The spectrum of sepsis-associated encephalopathy: A clinical perspective. Crit. Care 27, 386 (2023).","journal-title":"Crit. Care"},{"key":"45504_CR21","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1186\/s12964-024-01620-y","volume":"22","author":"X Qiao","year":"2024","unstructured":"Qiao, X., Yin, J., Zheng, Z., Li, L. & Feng, X. Endothelial cell dynamics in sepsis-induced acute lung injury and acute respiratory distress syndrome: Pathogenesis and therapeutic implications. Cell Commun. Signal. 22, 241 (2024).","journal-title":"Cell Commun. Signal."},{"key":"45504_CR22","doi-asserted-by":"publisher","first-page":"R84","DOI":"10.1186\/cc7904","volume":"13","author":"IA Meynaar","year":"2009","unstructured":"Meynaar, I. A. et al. Off hour admission to an intensivist-led ICU is not associated with increased mortality. Crit. Care 13, R84 (2009).","journal-title":"Crit. Care"},{"key":"45504_CR23","doi-asserted-by":"publisher","first-page":"895","DOI":"10.1007\/s00134-004-2170-3","volume":"30","author":"H Wunsch","year":"2004","unstructured":"Wunsch, H., Mapstone, J., Brady, T., Hanks, R. & Rowan, K. Hospital mortality associated with day and time of admission to intensive care units. Intensive Care Med. 30, 895\u2013901 (2004).","journal-title":"Intensive Care Med."}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41598-026-45504-2","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-026-45504-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-026-45504-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T09:50:55Z","timestamp":1774950655000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41598-026-45504-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,30]]},"references-count":23,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["45504"],"URL":"https:\/\/doi.org\/10.1038\/s41598-026-45504-2","relation":{},"ISSN":["2045-2322"],"issn-type":[{"value":"2045-2322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,30]]},"assertion":[{"value":"29 December 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 March 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 March 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"10626"}}