{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T23:17:10Z","timestamp":1782947830617,"version":"3.54.5"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T00:00:00Z","timestamp":1776988800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T00:00:00Z","timestamp":1782950400000},"content-version":"vor","delay-in-days":69,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"name":"Lalla Salma Foundation for Cancer Prevention and Treatment, Rabat, Morocco"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"DOI":"10.1038\/s41598-026-46200-x","type":"journal-article","created":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T05:44:18Z","timestamp":1777009458000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Feasibility and acceptability of HPV testing using GeneXpert for cervical cancer screening in Morocco"],"prefix":"10.1038","volume":"16","author":[{"given":"Nassiba","family":"Bahra","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Youssef","family":"Chami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachid","family":"Bekkali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Bennani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zineb","family":"Gaizi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatima Zahra","family":"Chellat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nabil","family":"Tachfouti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samira","family":"El Fakir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anasse","family":"Benabdallah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed","family":"El Mzibri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed","family":"Berraho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,4,24]]},"reference":[{"key":"46200_CR1","unstructured":"World Health Organization. Cancer du col de l\u2019ut\u00e9rus, accessed 20 May (2024). https:\/\/www.who.int\/fr\/news-room\/fact-sheets\/detail\/cervical-cancer (2024)."},{"issue":"6","key":"46200_CR2","doi-asserted-by":"publisher","first-page":"394","DOI":"10.3322\/caac.21492","volume":"68","author":"F Bray","year":"2018","unstructured":"Bray, F. et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J. Clin. 68 (6), 394\u2013424. https:\/\/doi.org\/10.3322\/caac.21492 (2018).","journal-title":"CA Cancer J. Clin."},{"key":"46200_CR3","unstructured":"Registre des Cancers de la R\u00e9gion du Grand Casablanca. Accessed 30 November 2024. https:\/\/www.contrelecancer.ma\/site_media\/uploaded_files\/Registre_des_Cancers_de_la_Region_du_Grand_Casablanca_2018-2021_1_nJ8oeD2.pdf (2018)."},{"key":"46200_CR4","unstructured":"Registre des Cancers de la R\u00e9gion du Grand. Casablanca 2013\u20132017. Accessed May 20. https:\/\/contrelecancer.ma\/site_media\/uploaded_files\/Registre_des_Cancers_de_la_Region_du_Grand_Casablanca_2013-2017.pdf (2024)."},{"key":"46200_CR5","unstructured":"International Agency for Research on Cancer. Morocco fact sheet. Accessed May 20. https:\/\/gco.iarc.who.int\/media\/globocan\/factsheets\/populations\/504-morocco-fact-sheet.pdf (2024).\u00a0"},{"issue":"5","key":"46200_CR6","doi-asserted-by":"publisher","first-page":"1095","DOI":"10.1002\/ijc.21955","volume":"119","author":"J Cuzick","year":"2006","unstructured":"Cuzick, J. et al. Overview of the European and North American studies on HPV testing in primary cervical cancer screening. Int. J. Cancer. 119 (5), 1095\u20131101. https:\/\/doi.org\/10.1002\/ijc.21955 (2006).","journal-title":"Int. J. Cancer"},{"issue":"6","key":"46200_CR7","doi-asserted-by":"publisher","first-page":"342","DOI":"10.1038\/nrc798","volume":"2","author":"H zur Hausen","year":"2002","unstructured":"zur Hausen, H. Papillomaviruses and cancer: From basic studies to clinical application. Nat. Rev. Cancer. 2 (6), 342\u2013350. https:\/\/doi.org\/10.1038\/nrc798 (2002).","journal-title":"Nat. Rev. Cancer"},{"issue":"5","key":"46200_CR8","doi-asserted-by":"publisher","first-page":"368","DOI":"10.1093\/jnci\/djq562","volume":"103","author":"M Schiffman","year":"2011","unstructured":"Schiffman, M. et al. Human papillomavirus testing in the prevention of cervical cancer. J. Natl. Cancer Inst. 103 (5), 368\u2013383. https:\/\/doi.org\/10.1093\/jnci\/djq562 (2011).","journal-title":"J. Natl. Cancer Inst."},{"key":"46200_CR9","unstructured":"World Health Organization. Cervical cancer elimination strategy. Accessed May 20. https:\/\/www.who.int\/docs\/default-source\/cervical-cancer\/cervical-cancer-elimination-strategy-fr.pdf (2024)."},{"key":"46200_CR10","unstructured":"Ministry of Health, Morocco. Plan national de pr\u00e9vention et de contr\u00f4le du cancer 2020\u20132029. https:\/\/www.sante.gov.ma\/Documents\/2021\/03\/Plan_National_de_Prevention_et_de_Controle_du_Cancer_2020-2029_VF.pdf?csf=1&e=ejDjaj. Accessed April 20 (2024)."},{"key":"46200_CR11","unstructured":"World Health Organization. Lignes directrices de l\u2019OMS pour le d\u00e9pistage et le traitement des l\u00e9sions pr\u00e9canc\u00e9reuses pour la pr\u00e9vention du cancer du col de l\u2019ut\u00e9rus. World Health Organization.  https:\/\/iris.who.int\/handle\/10665\/112555. Accessed May 20, 2024 (2014)."},{"key":"46200_CR12","unstructured":"World Health Organization. Morocco: Human Papillomavirus and Related Cancers, Fact Sheet 2023 (World Health Organization, 2023)."},{"key":"46200_CR13","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1186\/s13027-017-0140-3","volume":"12","author":"RS Bouassa","year":"2017","unstructured":"Bouassa, R. S. et al. Human papillomavirus genotype distribution in North Africa: A systematic review and meta-analysis. Infect. Agents Cancer. 12, 30. https:\/\/doi.org\/10.1186\/s13027-017-0140-3 (2017).","journal-title":"Infect. Agents Cancer"},{"issue":"11","key":"46200_CR14","doi-asserted-by":"publisher","first-page":"732","DOI":"10.3855\/jidc.781","volume":"4","author":"Z Alhamany","year":"2010","unstructured":"Alhamany, Z. et al. Prevalence of human papillomavirus genotype among Moroccan women during a local screening program. J. Infect. Dev. Ctries. 4 (11), 732\u2013739. https:\/\/doi.org\/10.3855\/jidc.781 (2010).","journal-title":"J. Infect. Dev. Ctries."},{"issue":"3","key":"46200_CR15","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1093\/heapro\/dar097","volume":"28","author":"AJ Milat","year":"2013","unstructured":"Milat, A. J., King, L., Bauman, A. E. & Redman, S. The concept of scalability: Increasing the scale and potential adoption of health promotion interventions into policy and practice. Health Promot. Int. 28 (3), 285\u2013298. https:\/\/doi.org\/10.1093\/heapro\/dar097 (2013).","journal-title":"Health Promot. Int."},{"key":"46200_CR16","doi-asserted-by":"publisher","first-page":"1104","DOI":"10.1186\/s12889-024-18551-5","volume":"24","author":"S-F Ngu","year":"2024","unstructured":"Ngu, S-F. et al. Acceptability of self-collected vaginal samples for human papillomavirus testing for primary cervical cancer screening: Comparison of face-to-face and online recruitment modes. BMC Public. Health. 24, 1104. https:\/\/doi.org\/10.1186\/s12889-024-18551-5 (2024).","journal-title":"BMC Public. Health"},{"issue":"Suppl 1","key":"46200_CR17","doi-asserted-by":"publisher","first-page":"S227","DOI":"10.1016\/j.ygyno.2023.06.275","volume":"176","author":"J Ruel-Lalibert\u00e9","year":"2023","unstructured":"Ruel-Lalibert\u00e9, J. Acceptability and preferences of dry HPV self-sampling among Canadian women: A cross-sectional study (2150). Gynecol. Oncol. 176 (Suppl 1), S227\u2013S228. https:\/\/doi.org\/10.1016\/j.ygyno.2023.06.275 (2023).","journal-title":"Gynecol. Oncol."},{"key":"46200_CR18","unstructured":"Mensah, K. D\u00e9pistage opportuniste du cancer du col par test HPV dans les pays \u00e0 faibles et moyens revenus: Exemples du Burkina Faso et de la C\u00f4te d\u2019Ivoire. Th\u00e8se de doctorat, Universit\u00e9 Paris Cit\u00e9, 09\/11\/2021."},{"issue":"2","key":"46200_CR19","doi-asserted-by":"publisher","first-page":"e0262213","DOI":"10.1371\/journal.pone.0262213","volume":"17","author":"L Chaw","year":"2022","unstructured":"Chaw, L., Lee, S. H. F., Ja\u2019afar, N. I. H., Lim, E. & Sharbawi, R. Reasons for nonattendance to cervical cancer screening and acceptability of HPV self-sampling among Bruneian women: A cross-sectional study. PLoS ONE. 17 (2), e0262213. https:\/\/doi.org\/10.1371\/journal.pone.0262213 (2022).","journal-title":"PLoS ONE"},{"issue":"1","key":"46200_CR20","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1309\/AJCP4Q0NSDHWIZGU","volume":"143","author":"PE Castle","year":"2015","unstructured":"Castle, P. E. et al. Reliability of the Xpert HPV assay to detect high-risk human papillomavirus DNA in a colposcopy referral population. Am. J. Clin. Pathol. 143 (1), 126\u2013133. https:\/\/doi.org\/10.1309\/AJCP4Q0NSDHWIZGU (2015).","journal-title":"Am. J. Clin. Pathol."},{"key":"46200_CR21","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1186\/s12885-017-3425-z","volume":"17","author":"M Berraho","year":"2017","unstructured":"Berraho, M. et al. HPV and cofactors for invasive cervical cancer in Morocco: A multicenter case\u2013control study. BMC Cancer. 17, 435. https:\/\/doi.org\/10.1186\/s12885-017-3425-z (2017).","journal-title":"BMC Cancer"},{"issue":"6","key":"46200_CR22","doi-asserted-by":"publisher","first-page":"e772","DOI":"10.1016\/S2214-109X(19)30048-8","volume":"7","author":"S Arrossi","year":"2019","unstructured":"Arrossi, S. et al. Programmatic human papillomavirus testing in cervical cancer prevention in the Jujuy Demonstration Project in Argentina: A population-based, before-and-after retrospective cohort study. Lancet Glob Health. 7 (6), e772\u2013e783. https:\/\/doi.org\/10.1016\/S2214-109X(19)30048-8 (2019).","journal-title":"Lancet Glob. Health"},{"issue":"12","key":"46200_CR23","doi-asserted-by":"publisher","first-page":"1789","DOI":"10.1086\/657321","volume":"202","author":"L Bruni","year":"2010","unstructured":"Bruni, L. et al. Cervical human papillomavirus prevalence in 5 continents: Meta-analysis of 1 million women with normal cytological findings. J. Infect. Dis. 202 (12), 1789\u20131799. https:\/\/doi.org\/10.1086\/657321 (2010).","journal-title":"J. Infect. Dis."},{"issue":"7","key":"46200_CR24","doi-asserted-by":"publisher","first-page":"1665","DOI":"10.1002\/ijc.29143","volume":"136","author":"JC Gage","year":"2015","unstructured":"Gage, J. C. et al. Age-stratified 5-year risks of cervical precancer among women with enrollment and newly detected HPV infection. Int. J. Cancer. 136 (7), 1665\u20131671. https:\/\/doi.org\/10.1002\/ijc.29143 (2015).","journal-title":"Int. J. Cancer"},{"key":"46200_CR25","unstructured":"Organization mondiale de la Sant\u00e9. Vers une extension du d\u00e9pistage du cancer du col de l\u2019ut\u00e9rus au Kenya. OMS, Bureau r\u00e9gional pour l\u2019Afrique. Disponible sur. https:\/\/www.afro.who.int\/fr\/countries\/kenya\/news\/vers-une-extension-du-depistage-du-cancer-du-col-de-luterus-au-kenya. Acc\u00e9d\u00e9 le 26 septembre 2024 (2023)."},{"key":"46200_CR26","doi-asserted-by":"publisher","first-page":"e0181905","DOI":"10.1371\/journal.pone.0181905","volume":"12","author":"R Catarino","year":"2017","unstructured":"Catarino, R. et al. Accuracy of self-collected vaginal dry swabs using the Xpert human papillomavirus assay. PLoS One. 12, e0181905. https:\/\/doi.org\/10.1371\/journal.pone.0181905 (2017).","journal-title":"PLoS One"},{"key":"46200_CR27","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1016\/j.pvr.2016.02.004","volume":"2","author":"ZZA Mbulawa","year":"2016","unstructured":"Mbulawa, Z. Z. A. et al. Xpert human papillomavirus test is a promising cervical cancer screening test for HIV-seropositive women. Papillomavirus Res. 2, 56\u201360. https:\/\/doi.org\/10.1016\/j.pvr.2016.02.004 (2016).","journal-title":"Papillomavirus Res."},{"issue":"1","key":"46200_CR28","doi-asserted-by":"publisher","first-page":"942","DOI":"10.54112\/bcsrj.v2024i1.942","volume":"2024","author":"N Bukhari","year":"2024","unstructured":"Bukhari, N. et al. The influence of various risk factors on the correlation between HPV infection and the advancement of cervical carcinoma. Biol. Clin. Sci. Res. J. 2024 (1), 942\u2013942. https:\/\/doi.org\/10.54112\/bcsrj.v2024i1.942 (2024).","journal-title":"Biol. Clin. Sci. Res. J."},{"key":"46200_CR29","doi-asserted-by":"publisher","first-page":"101301","DOI":"10.1016\/j.pmedr.2020.101301","volume":"21","author":"NL Kops","year":"2021","unstructured":"Kops, N. L. et al. The impact of socioeconomic status on HPV infection among young Brazilians in a nationwide multicenter study. Prev. Med. Rep. 21, 101301. https:\/\/doi.org\/10.1016\/j.pmedr.2020.101301 (2021).","journal-title":"Prev. Med. Rep."},{"key":"46200_CR30","doi-asserted-by":"publisher","first-page":"1399192","DOI":"10.3389\/fpubh.2024.1399192","volume":"12","author":"X Gong","year":"2024","unstructured":"Gong, X., Xu, J., He, Y., Zou, G. & Liu, J. Socioeconomic inequalities in human papillomavirus knowledge and vaccine uptake: Evidence from a cross-sectional study in China. Front. Public. Health. 12, 1399192. https:\/\/doi.org\/10.3389\/fpubh.2024.1399192 (2024).","journal-title":"Front. Public. Health"}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41598-026-46200-x","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-026-46200-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-026-46200-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T22:24:10Z","timestamp":1782944650000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41598-026-46200-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,24]]},"references-count":30,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["46200"],"URL":"https:\/\/doi.org\/10.1038\/s41598-026-46200-x","relation":{},"ISSN":["2045-2322"],"issn-type":[{"value":"2045-2322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,24]]},"assertion":[{"value":"23 September 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 March 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 April 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"The study protocol was approved by the Ethics Committee of Medical Research at the Faculty of Medicine and Pharmacy in Rabat (Ref 31\u2009\u2212\u200922). Written informed consent was obtained from all women prior to enrolment. Participation was voluntary, and confidentiality of data was ensured throughout the study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}],"article-number":"20157"}}