{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T14:46:36Z","timestamp":1790952396783,"version":"4.1.0"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,4,5]],"date-time":"2026-04-05T00:00:00Z","timestamp":1775347200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T00:00:00Z","timestamp":1779840000000},"content-version":"vor","delay-in-days":52,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"DOI":"10.1038\/s41598-026-47169-3","type":"journal-article","created":{"date-parts":[[2026,4,5]],"date-time":"2026-04-05T05:54:29Z","timestamp":1775368469000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Impact of albumin variability during the first year on prognosis in peritoneal dialysis patients"],"prefix":"10.1038","volume":"16","author":[{"given":"Yonglong","family":"Min","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nan","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenhui","family":"Qiu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuai","family":"Fu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheng","family":"Wan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenli","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaofei","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanmin","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fei","family":"Xiong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,4,5]]},"reference":[{"issue":"3","key":"47169_CR1","doi-asserted-by":"publisher","first-page":"e382","DOI":"10.1016\/S2214-109X(23)00570-3","volume":"12","author":"AK Bello","year":"2024","unstructured":"Bello, A. K. et al. An update on the global disparities in kidney disease burden and care across world countries and regions. Lancet Glob Health. 12 (3), e382\u2013e395. https:\/\/doi.org\/10.1016\/S2214-109X(23)00570-3 (2024).","journal-title":"Lancet Glob Health"},{"issue":"1","key":"47169_CR2","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1186\/s12877-024-04931-4","volume":"24","author":"S Guo","year":"2024","unstructured":"Guo, S. et al. Risk factors of different mortality periods in older patients with end-stage renal disease undergoing urgent-start peritoneal dialysis: a retrospective observational study. BMC Geriatr. 24 (1), 343. https:\/\/doi.org\/10.1186\/s12877-024-04931-4 (2024).","journal-title":"BMC Geriatr."},{"key":"47169_CR3","doi-asserted-by":"publisher","first-page":"32359","DOI":"10.1038\/srep32359","volume":"6","author":"X Liu","year":"2016","unstructured":"Liu, X. et al. Patient characteristics and risk factors of early and late death in incident peritoneal dialysis patients. Sci. Rep. 6, 32359. https:\/\/doi.org\/10.1038\/srep32359 (2016).","journal-title":"Sci. Rep."},{"issue":"2\u20133","key":"47169_CR4","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1016\/j.ejvs.2022.03.045","volume":"64","author":"TY Lin","year":"2022","unstructured":"Lin, T. Y. et al. Malnutrition is Associated with Increased Morbidity and Death in Dialysis Patients Undergoing Endovascular Therapy for Peripheral Artery Disease. Eur. J. Vasc Endovasc Surg. 64 (2\u20133), 225\u2013233. https:\/\/doi.org\/10.1016\/j.ejvs.2022.03.045 (2022).","journal-title":"Eur. J. Vasc Endovasc Surg."},{"issue":"1","key":"47169_CR5","doi-asserted-by":"publisher","first-page":"252","DOI":"10.1080\/0886022X.2022.2033264","volume":"44","author":"L Jin","year":"2022","unstructured":"Jin, L. et al. Serum albumin at 1 year after peritoneal dialysis predicts long-term outcomes on continuous ambulatory peritoneal dialysis. Ren. Fail. 44 (1), 252\u2013257. https:\/\/doi.org\/10.1080\/0886022X.2022.2033264 (2022).","journal-title":"Ren. Fail."},{"issue":"3","key":"47169_CR6","doi-asserted-by":"publisher","first-page":"565","DOI":"10.1007\/s11255-020-02389-y","volume":"52","author":"X Wang","year":"2020","unstructured":"Wang, X. et al. Serum albumin changes and mortality risk of peritoneal dialysis patients. Int. Urol. Nephrol. 52 (3), 565\u2013571. https:\/\/doi.org\/10.1007\/s11255-020-02389-y (2020).","journal-title":"Int. Urol. Nephrol."},{"key":"47169_CR7","doi-asserted-by":"publisher","DOI":"10.1111\/1744-9987.14244","author":"J Li","year":"2025","unstructured":"Li, J. et al. Dynamic changes in serum albumin and ferritin indicate higher risk of early-onset peritonitis in peritoneal dialysis patients. Ther. Apher Dial. https:\/\/doi.org\/10.1111\/1744-9987.14244 (2025).","journal-title":"Ther. Apher Dial"},{"issue":"1","key":"47169_CR8","doi-asserted-by":"publisher","first-page":"17","DOI":"10.5414\/CN111162","volume":"101","author":"ML Li","year":"2024","unstructured":"Li, M. L. et al. Characteristics of registered research in peritoneal dialysis: Past and present. Clin. Nephrol. 101 (1), 17\u201324. https:\/\/doi.org\/10.5414\/CN111162 (2024).","journal-title":"Clin. Nephrol."},{"issue":"2","key":"47169_CR9","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1038\/nrneph.2016.181","volume":"13","author":"PK Li","year":"2017","unstructured":"Li, P. K. et al. Changes in the worldwide epidemiology of peritoneal dialysis. Nat. Rev. Nephrol. 13 (2), 90\u2013103. https:\/\/doi.org\/10.1038\/nrneph.2016.181 (2017).","journal-title":"Nat. Rev. Nephrol."},{"issue":"2","key":"47169_CR10","doi-asserted-by":"publisher","first-page":"188","DOI":"10.1053\/j.ajkd.2017.10.019","volume":"72","author":"EJ See","year":"2018","unstructured":"See, E. J. et al. Risk Predictors and Causes of Technique Failure Within the First Year of Peritoneal Dialysis: An Australia and New Zealand Dialysis and Transplant Registry (ANZDATA) Study. Am. J. Kidney Dis. 72 (2), 188\u2013197. https:\/\/doi.org\/10.1053\/j.ajkd.2017.10.019 (2018).","journal-title":"Am. J. Kidney Dis."},{"issue":"5","key":"47169_CR11","doi-asserted-by":"publisher","first-page":"319","DOI":"10.3747\/pdi.2018.00017","volume":"38","author":"Y Cho","year":"2018","unstructured":"Cho, Y. et al. Early Peritoneal Dialysis Technique Failure: Review. Perit. Dial Int. 38 (5), 319\u2013327. https:\/\/doi.org\/10.3747\/pdi.2018.00017 (2018).","journal-title":"Perit. Dial Int."},{"issue":"43","key":"47169_CR12","doi-asserted-by":"publisher","first-page":"e27666","DOI":"10.1097\/MD.0000000000027666","volume":"100","author":"C Chen","year":"2021","unstructured":"Chen, C. et al. Impact of serum albumin level and variability on short-term cardiovascular-related and all-cause mortality in patients on maintenance hemodialysis. Med. (Baltim). 100 (43), e27666. https:\/\/doi.org\/10.1097\/MD.0000000000027666 (2021).","journal-title":"Med. (Baltim)."},{"key":"47169_CR13","doi-asserted-by":"publisher","first-page":"917603","DOI":"10.3389\/fmed.2022.917603","volume":"9","author":"P Song","year":"2022","unstructured":"Song, P. et al. Dynamic serum albumin and outcome of peritoneal dialysis patients: A retrospective study in China. Front. Med. (Lausanne). 9, 917603. https:\/\/doi.org\/10.3389\/fmed.2022.917603 (2022).","journal-title":"Front. Med. (Lausanne)"},{"issue":"12","key":"47169_CR14","doi-asserted-by":"publisher","first-page":"e3202","DOI":"10.1097\/MD.0000000000003202","volume":"95","author":"PF Chiu","year":"2016","unstructured":"Chiu, P. F. et al. Trajectories of Serum Albumin Predict Survival of Peritoneal Dialysis Patients: A 15-year Follow-Up Study. Med. (Baltim). 95 (12), e3202. https:\/\/doi.org\/10.1097\/MD.0000000000003202 (2016).","journal-title":"Med. (Baltim)."},{"key":"47169_CR15","doi-asserted-by":"publisher","first-page":"884061","DOI":"10.3389\/fmed.2022.884061","volume":"9","author":"GA Malho","year":"2022","unstructured":"Malho, G. A. et al. Peritoneal Protein Loss, Inflammation, and Nutrition: Refuting Myths. Front. Med. (Lausanne). 9, 884061. https:\/\/doi.org\/10.3389\/fmed.2022.884061 (2022).","journal-title":"Front. Med. (Lausanne)"},{"issue":"11","key":"47169_CR16","doi-asserted-by":"publisher","first-page":"e276159","DOI":"10.1371\/journal.pone.0276159","volume":"17","author":"YT Huang","year":"2022","unstructured":"Huang, Y. T., Jiang, M. Y. & Hwang, J. C. Albumin to prealbumin ratio in peritoneal dialysis patients: Clinical implication and outcome prediction. PLoS One. 17 (11), e276159. https:\/\/doi.org\/10.1371\/journal.pone.0276159 (2022).","journal-title":"PLoS One"},{"key":"47169_CR17","doi-asserted-by":"publisher","first-page":"1393513","DOI":"10.3389\/fcvm.2024.1393513","volume":"11","author":"Y Liu","year":"2024","unstructured":"Liu, Y. et al. Associations between neutrophil-percentage-to-albumin ratio level and all-cause mortality and cardiovascular disease-cause mortality in general population: evidence from NHANES 1999\u20132010. Front. Cardiovasc. Med. 11, 1393513. https:\/\/doi.org\/10.3389\/fcvm.2024.1393513 (2024).","journal-title":"Front. Cardiovasc. Med."},{"issue":"3","key":"47169_CR18","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1111\/hdi.13232","volume":"29","author":"JC Castillo","year":"2025","unstructured":"Castillo, J. C. et al. Variations in Serum Albumin Levels Over Time in Patients Treated With Conventional Hemodialysis or Expanded Hemodialysis: A Cohort Study. Hemodial. Int. 29 (3), 327\u2013334. https:\/\/doi.org\/10.1111\/hdi.13232 (2025).","journal-title":"Hemodial. Int."},{"issue":"2","key":"47169_CR19","doi-asserted-by":"publisher","first-page":"e29949","DOI":"10.1136\/bmjopen-2019-029949","volume":"10","author":"X Ma","year":"2020","unstructured":"Ma, X. et al. Analysis of risk factors and outcome in peritoneal dialysis patients with early-onset peritonitis: a multicentre, retrospective cohort study. BMJ Open. 10 (2), e29949. https:\/\/doi.org\/10.1136\/bmjopen-2019-029949 (2020).","journal-title":"BMJ Open."},{"issue":"1","key":"47169_CR20","doi-asserted-by":"publisher","first-page":"2294149","DOI":"10.1080\/0886022X.2023.2294149","volume":"46","author":"M Xu","year":"2024","unstructured":"Xu, M. et al. The neutrophil percentage-to-albumin ratio is an independent risk factor for poor prognosis in peritoneal dialysis patients. Ren. Fail. 46 (1), 2294149. https:\/\/doi.org\/10.1080\/0886022X.2023.2294149 (2024).","journal-title":"Ren. Fail."},{"issue":"1","key":"47169_CR21","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1186\/s12882-024-03792-8","volume":"25","author":"H Ma","year":"2024","unstructured":"Ma, H. et al. Platelet-to-albumin ratio: a potential biomarker for predicting all-cause and cardiovascular mortality in patients undergoing peritoneal dialysis. BMC Nephrol. 25 (1), 365. https:\/\/doi.org\/10.1186\/s12882-024-03792-8 (2024).","journal-title":"BMC Nephrol."},{"key":"47169_CR22","doi-asserted-by":"publisher","DOI":"10.1007\/s11255-025-04679-9","author":"X Guo","year":"2025","unstructured":"Guo, X. et al. The prognostic role of hemoglobin, albumin, lymphocyte, and platelets score in peritoneal dialysis. Int. Urol. Nephrol. https:\/\/doi.org\/10.1007\/s11255-025-04679-9 (2025).","journal-title":"Int. Urol. Nephrol."},{"issue":"4","key":"47169_CR23","doi-asserted-by":"publisher","first-page":"496","DOI":"10.34067\/KID.0000000778","volume":"6","author":"M Salani","year":"2025","unstructured":"Salani, M. Strategies to Reduce Technique Failure in Peritoneal Dialysis. Kidney360 6 (4), 496\u2013497. https:\/\/doi.org\/10.34067\/KID.0000000778 (2025).","journal-title":"Kidney360"},{"issue":"2","key":"47169_CR24","doi-asserted-by":"publisher","first-page":"2274965","DOI":"10.1080\/0886022X.2023.2274965","volume":"45","author":"W Xie","year":"2023","unstructured":"Xie, W. et al. Clinical risk factors for peritoneal dialysis withdrawal at different dialysis duration. Ren. Fail. 45 (2), 2274965. https:\/\/doi.org\/10.1080\/0886022X.2023.2274965 (2023).","journal-title":"Ren. Fail."},{"issue":"4","key":"47169_CR25","doi-asserted-by":"publisher","first-page":"481","DOI":"10.1053\/j.ajkd.2023.03.011","volume":"82","author":"SF Khan","year":"2023","unstructured":"Khan, S. F. Updates on Infectious and Other Complications in Peritoneal Dialysis: Core Curriculum 2023. Am. J. Kidney Dis. 82 (4), 481\u2013490. https:\/\/doi.org\/10.1053\/j.ajkd.2023.03.011 (2023).","journal-title":"Am. J. Kidney Dis."},{"issue":"1","key":"47169_CR26","doi-asserted-by":"publisher","first-page":"743","DOI":"10.1080\/0886022X.2021.1918558","volume":"43","author":"J Zhang","year":"2021","unstructured":"Zhang, J. et al. Risk factors for mortality in patients undergoing peritoneal dialysis: a systematic review and meta-analysis. Ren. Fail. 43 (1), 743\u2013753. https:\/\/doi.org\/10.1080\/0886022X.2021.1918558 (2021).","journal-title":"Ren. Fail."},{"key":"47169_CR27","doi-asserted-by":"publisher","unstructured":"Lai, K. J. et al. Association of albumin and globulin with mortality risk in incident peritoneal dialysis patients. Nutrients 14 (14). https:\/\/doi.org\/10.3390\/nu14142850 (2022).","DOI":"10.3390\/nu14142850"},{"issue":"11","key":"47169_CR28","doi-asserted-by":"publisher","first-page":"2017","DOI":"10.1093\/cvr\/cvad083","volume":"119","author":"C Zoccali","year":"2023","unstructured":"Zoccali, C. et al. Cardiovascular complications in chronic kidney disease: a review from the European Renal and Cardiovascular Medicine Working Group of the European Renal Association. Cardiovasc. Res. 119 (11), 2017\u20132032. https:\/\/doi.org\/10.1093\/cvr\/cvad083 (2023).","journal-title":"Cardiovasc. Res."}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41598-026-47169-3","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-026-47169-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-026-47169-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T23:45:40Z","timestamp":1779839140000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41598-026-47169-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,5]]},"references-count":28,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["47169"],"URL":"https:\/\/doi.org\/10.1038\/s41598-026-47169-3","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-7800922\/v1","asserted-by":"object"}]},"ISSN":["2045-2322"],"issn-type":[{"value":"2045-2322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,5]]},"assertion":[{"value":"7 October 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 March 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 April 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"16395"}}