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The world is now using nanoparticles, particularly through green synthesis, as an effective alternative to traditional antimicrobials. Selenium nanoparticles (Se NPs) were produced from the\n                    <jats:italic>Olea europaea<\/jats:italic>\n                    plant extract and have been characterized using UV-Visible, FTIR, SEM, EDX, zeta potential, and HR-TEM. The antimicrobial effectiveness of Se NPs was evaluated against several microbial strains, including\n                    <jats:italic>Staphylococcus aureus<\/jats:italic>\n                    ,\n                    <jats:italic>Escherichia coli<\/jats:italic>\n                    ,\n                    <jats:italic>Klebsiella pneumoniae<\/jats:italic>\n                    ,\n                    <jats:italic>Citrobacter freundii<\/jats:italic>\n                    , and\n                    <jats:italic>Candida albicans<\/jats:italic>\n                    , and its impact on their biofilm formation was tested. The UV-Vis spectrophotometer results displayed the highest absorption at 380\u00a0nm, indicating the synthesis of selenium nanoparticles. The biosynthesized Se NPs were uniform, well-dispersed, quasi-spherical in shape, and with particle sizes ranging from 2.60 to 4.75\u00a0nm. The antimicrobial activity analysis of Se NPs showed that\n                    <jats:italic>C. albicans<\/jats:italic>\n                    was mostly inhibited, recording an inhibition zone diameter of 35.98\u2009\u00b1\u20090.65\u00a0mm at 150\u00a0\u00b5g\/mL. The antibiofilm assessment represented a 59.04% inhibition of\n                    <jats:italic>C. albicans<\/jats:italic>\n                    biofilm. In conclusion, Se NPs have proven to be economical, less toxic, and environmentally friendly antimicrobial agents for preventing and treating many bacterial and fungal infections.\n                  <\/jats:p>","DOI":"10.1038\/s41598-026-47329-5","type":"journal-article","created":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T09:02:28Z","timestamp":1778922148000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Facile green synthesis of selenium nanoparticles using olive (Olea europaea) leaf extract and their antimicrobial and antibiofilm properties"],"prefix":"10.1038","volume":"16","author":[{"given":"Sama E.","family":"Hassan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nada M.","family":"Khedr","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Esraa M.","family":"Omran","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara R.","family":"Mohamed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nourhan A.","family":"Gemail","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdelrahman A.","family":"Elsharawy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dina M.","family":"Baraka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2902-2882","authenticated-orcid":false,"given":"Rasha Mohammad","family":"Fathy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,5,16]]},"reference":[{"key":"47329_CR1","doi-asserted-by":"crossref","unstructured":"Wani, M. 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