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If no such relationship exists, authors will be asked to confirm the following statement:","order":2,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All experiments were performed with at least three independent replicates, and the animals were randomly divided into experimental groups. The charts were created using GraphPad Prism 7.0 software (San Diego, CA, USA). The data are expressed as mean\u00b1standard error of the mean (SEM). Statistical analyses were performed using one-way Analysis of Variance (ANOVA), with post-hoc Tukey\u2019s multiple comparison test conducted in Prism software. 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