{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:37:33Z","timestamp":1786120653335,"version":"build-2736575974"},"reference-count":51,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T00:00:00Z","timestamp":1779926400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T00:00:00Z","timestamp":1786060800000},"content-version":"vor","delay-in-days":71,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"DOI":"10.1038\/s41598-026-54546-5","type":"journal-article","created":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T09:42:26Z","timestamp":1779961346000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Regulation of SNHG1, SNHG3, SNHG4 and SNHG5 in peripheral blood mononuclear cells in rheumatoid arthritis"],"prefix":"10.1038","volume":"16","author":[{"given":"Dominika","family":"Podg\u00f3rska","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marek","family":"Cie\u015bla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joanna","family":"Pa\u015bko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bogdan","family":"Kolarz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,5,28]]},"reference":[{"key":"54546_CR1","doi-asserted-by":"publisher","first-page":"2205","DOI":"10.1056\/NEJMra1004965","volume":"365","author":"IB McInnes","year":"2011","unstructured":"McInnes, I. B. & Schett, G. The pathogenesis of rheumatoid arthritis. N. Engl. J. Med. 365, 2205\u20132219 (2011).","journal-title":"N. Engl. J. Med."},{"key":"54546_CR2","doi-asserted-by":"publisher","first-page":"2328","DOI":"10.1016\/S0140-6736(17)31472-1","volume":"389","author":"IB McInnes","year":"2017","unstructured":"McInnes, I. B. & Schett, G. Pathogenetic insights from the treatment of rheumatoid arthritis. Lancet 389, 2328\u20132337 (2017).","journal-title":"Lancet"},{"key":"54546_CR3","doi-asserted-by":"publisher","first-page":"18001","DOI":"10.1038\/nrdp.2018.1","volume":"4","author":"JS Smolen","year":"2018","unstructured":"Smolen, J. S. et al. Rheumatoid arthritis. Nat. Rev. Dis. Primers. 4, 18001 (2018).","journal-title":"Nat. Rev. Dis. Primers"},{"key":"54546_CR4","doi-asserted-by":"publisher","DOI":"10.1002\/mco2.509","volume":"5","author":"Y Gao","year":"2024","unstructured":"Gao, Y., Zhang, Y. & Liu, X. Rheumatoid arthritis: Pathogenesis and therapeutic advances. MedComm (2020) 5, e509 (2024).","journal-title":"MedComm (2020)"},{"key":"54546_CR5","first-page":"1","volume":"8","author":"Q Ding","year":"2023","unstructured":"Ding, Q. et al. Signaling pathways in rheumatoid arthritis: Implications for targeted therapy. Signal Transduct. Target. Ther. 8, 1\u201324 (2023).","journal-title":"Signal Transduct. Target. Ther."},{"key":"54546_CR6","unstructured":"Yue, S. et al. Unveiling the Therapeutic Potential: Targeting Fibroblast-like Synoviocytes in Rheumatoid Arthritis | Expert Reviews in Molecular Medicine | Cambridge Core. https:\/\/www.cambridge.org\/core\/journals\/expert-reviews-in-molecular-medicine\/article\/unveiling-the-therapeutic-potential-targeting-fibroblastlike-synoviocytes-in-rheumatoid-arthritis\/F321518B5E9ABC5665D8558B597012D9"},{"key":"54546_CR7","doi-asserted-by":"publisher","first-page":"1318","DOI":"10.1111\/1756-185X.13930","volume":"23","author":"J Cao","year":"2020","unstructured":"Cao, J. et al. LncRNA GAS5 activates the AMPK pathway in peripheral blood mononuclear cells derived from rheumatoid arthritis patients. Int. J. Rheum. Dis. 23, 1318\u20131327 (2020).","journal-title":"Int. J. Rheum. Dis."},{"key":"54546_CR8","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2020.01975","volume":"11","author":"Y Wang","year":"2020","unstructured":"Wang, Y. et al. LncRNA NEAT1 targets fibroblast-like synoviocytes in rheumatoid arthritis via the miR-410-3p\/YY1 axis. Front. Immunol. 11, 1975 (2020).","journal-title":"Front. Immunol."},{"key":"54546_CR9","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-44053-w","volume":"14","author":"M Elhai","year":"2023","unstructured":"Elhai, M. et al. The long non-coding RNA HOTAIR contributes to joint-specific gene expression in rheumatoid arthritis. Nat. Commun. 14, 8172 (2023).","journal-title":"Nat. Commun."},{"key":"54546_CR10","doi-asserted-by":"publisher","first-page":"560","DOI":"10.3390\/ijms26020560","volume":"26","author":"K Kie\u0142bowski","year":"2025","unstructured":"Kie\u0142bowski, K. et al. The Role of Long Non-Coding RNA in Rheumatoid Arthritis. Int. J. Mol. Sci. 26, 560 (2025).","journal-title":"Int. J. Mol. Sci."},{"key":"54546_CR11","doi-asserted-by":"publisher","first-page":"1486476","DOI":"10.3389\/fimmu.2024.1486476","volume":"15","author":"D Seyedi","year":"2024","unstructured":"Seyedi, D. et al. Noncoding RNAs in rheumatoid arthritis: Modulators of the NF-\u03baB signaling pathway and therapeutic implications. Front. Immunol.\u00a015, 1486476. https:\/\/doi.org\/10.3389\/fimmu.2024.1486476 (2024).","journal-title":"Front. Immunol."},{"key":"54546_CR12","doi-asserted-by":"publisher","first-page":"807738","DOI":"10.3389\/fimmu.2021.807738","volume":"12","author":"W Huang","year":"2022","unstructured":"Huang, W. et al. LncRNAs and rheumatoid arthritis: From identifying mechanisms to clinical investigation. Front. Immunol. 12, 807738. https:\/\/doi.org\/10.3389\/fimmu.2021.807738 (2022).","journal-title":"Front. Immunol."},{"key":"54546_CR13","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2023.1301545","volume":"14","author":"Z Wei","year":"2024","unstructured":"Wei, Z., Li, H., Lv, S. & Yang, J. Current situation and trend of non-coding RNA in rheumatoid arthritis: A review and bibliometric analysis. Front. Immunol. 14, 1301545 (2024).","journal-title":"Front. Immunol."},{"key":"54546_CR14","doi-asserted-by":"publisher","first-page":"607585","DOI":"10.3389\/fmed.2021.607585","volume":"8","author":"W Shi","year":"2021","unstructured":"Shi, W. et al. METTL3 promotes activation and inflammation of FLSs through the NF-\u03baB signaling pathway in rheumatoid arthritis. Front. Med. 8, 607585. https:\/\/doi.org\/10.3389\/fmed.2021.607585 (2021).","journal-title":"Front. Med."},{"key":"54546_CR15","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2025.145698","volume":"320","author":"Y Xu","year":"2025","unstructured":"Xu, Y. et al. METTL3 increases ferroptosis resistance to facilitate the tumor-like features of rheumatoid arthritis synovial fibroblasts through enhancing SLC7A11 mRNA stability in an m6A-IGF2BP2-dependent manner. Int. J. Biol. Macromol. 320, 145698 (2025).","journal-title":"Int. J. Biol. Macromol."},{"key":"54546_CR16","doi-asserted-by":"publisher","DOI":"10.1016\/j.yexcr.2024.114237","volume":"442","author":"Y Su","year":"2024","unstructured":"Su, Y. et al. Increased m6A RNA methylation and METTL3 expression may contribute to the synovitis progression of rheumatoid arthritis. Exp. Cell Res. 442, 114237 (2024).","journal-title":"Exp. Cell Res."},{"key":"54546_CR17","doi-asserted-by":"publisher","first-page":"107182","DOI":"10.1016\/j.intimp.2020.107182","volume":"90","author":"F Liu","year":"2021","unstructured":"Liu, F. et al. Long non-coding RNA SNHG1 regulates rheumatoid synovial invasion and proliferation by interaction with PTBP1. Int. Immunopharmacol. 90, 107182 (2021).","journal-title":"Int. Immunopharmacol."},{"key":"54546_CR18","doi-asserted-by":"publisher","first-page":"1153","DOI":"10.1093\/mr\/roae042","volume":"34","author":"K Li","year":"2024","unstructured":"Li, K. et al. LncRNA SNHG3 discriminates rheumatoid arthritis from healthy individuals and regulates inflammatory response and oxidative stress via modulating miR-128-3p. Mod. Rheumatol. 34, 1153\u20131161 (2024).","journal-title":"Mod. Rheumatol."},{"key":"54546_CR19","doi-asserted-by":"publisher","DOI":"10.1007\/s10238-025-01589-z","volume":"25","author":"A Golestanifar","year":"2025","unstructured":"Golestanifar, A. et al. Integrative analysis of lncRNAs in rheumatoid arthritis: From bioinformatics to experimental validation. Clin. Exp. Med. 25, 64 (2025).","journal-title":"Clin. Exp. Med."},{"key":"54546_CR20","doi-asserted-by":"publisher","first-page":"BSR20180540","DOI":"10.1042\/BSR20180540","volume":"38","author":"Z Xia","year":"2018","unstructured":"Xia, Z. et al. Decreased MiR-128-3p alleviates the progression of rheumatoid arthritis by up-regulating the expression of TNFAIP3. Biosci. Rep. 38, BSR20180540 (2018).","journal-title":"Biosci. Rep."},{"key":"54546_CR21","doi-asserted-by":"publisher","first-page":"3683","DOI":"10.2147\/DDDT.S245445","volume":"14","author":"S Zhang","year":"2020","unstructured":"Zhang, S. et al. LncRNA SNHG4 Attenuates Inflammatory Responses by Sponging miR-449c-5p and Up-Regulating STAT6 in Microglial During Cerebral Ischemia-Reperfusion Injury. Drug Des. Devel Ther. 14, 3683\u20133695 (2020).","journal-title":"Drug Des. Devel Ther."},{"key":"54546_CR22","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1016\/j.molimm.2021.08.008","volume":"139","author":"S-X Li","year":"2021","unstructured":"Li, S.-X. et al. Long noncoding RNA SNHG4 remits lipopolysaccharide-engendered inflammatory lung damage by inhibiting METTL3 - mediated m6A level of STAT2 mRNA. Mol. Immunol. 139, 10\u201322 (2021).","journal-title":"Mol. Immunol."},{"key":"54546_CR23","doi-asserted-by":"publisher","first-page":"e22866","DOI":"10.1002\/jbt.22866","volume":"35","author":"Y Yue","year":"2021","unstructured":"Yue, Y. et al. SNHG5 protects chondrocytes in interleukin-1\u03b2-stimulated osteoarthritis via regulating miR-181a-5p\/TGFBR3 axis. J. Biochem. Mol. Toxicol. 35, e22866 (2021).","journal-title":"J. Biochem. Mol. Toxicol."},{"key":"54546_CR24","doi-asserted-by":"publisher","first-page":"436","DOI":"10.1038\/sj.emboj.7601489","volume":"26","author":"GN Maine","year":"2007","unstructured":"Maine, G. N., Mao, X., Komarck, C. M. & Burstein, E. COMMD1 promotes the ubiquitination of NF-kappaB subunits through a cullin-containing ubiquitin ligase. EMBO J. 26, 436\u2013447 (2007).","journal-title":"EMBO J."},{"key":"54546_CR25","doi-asserted-by":"publisher","first-page":"1063","DOI":"10.1007\/s11010-020-03972-8","volume":"476","author":"J Wang","year":"2021","unstructured":"Wang, J., Zhang, Y. & Zhang, L. Long non-coding RNA SNHG5 suppresses the development of acute respiratory distress syndrome by targeting miR-205\/COMMD1 axis. Mol. Cell. Biochem. 476, 1063\u20131074 (2021).","journal-title":"Mol. Cell. Biochem."},{"key":"54546_CR26","doi-asserted-by":"publisher","first-page":"2119","DOI":"10.1172\/JCI40583","volume":"120","author":"B van de Sluis","year":"2010","unstructured":"van de Sluis, B. et al. COMMD1 disrupts HIF-1\u03b1\/\u03b2 dimerization and inhibits human tumor cell invasion. J. Clin. Invest. 120, 2119\u20132130 (2010).","journal-title":"J. Clin. Invest."},{"key":"54546_CR27","doi-asserted-by":"publisher","first-page":"1580","DOI":"10.1136\/ard.2010.138461","volume":"69","author":"D Aletaha","year":"2010","unstructured":"Aletaha, D. et al. 2010 rheumatoid arthritis classification criteria: an American College of Rheumatology\/European League Against Rheumatism collaborative initiative. Ann. Rheum. Dis. 69, 1580\u20131588 (2010).","journal-title":"Ann. Rheum. Dis."},{"key":"54546_CR28","doi-asserted-by":"publisher","first-page":"10995","DOI":"10.2147\/JIR.S524994","volume":"18","author":"M Cie\u015bla","year":"2025","unstructured":"Cie\u015bla, M., Darmochwa\u0142-Kolarz, D., Kubis, H. & Kolarz, B. Digital PCR-based assessment of Piwi-RNA PIR35982 as a supporting biomarker in rheumatoid arthritis. J. Inflamm. Res. 18, 10995\u201311007 (2025).","journal-title":"J. Inflamm. Res."},{"key":"54546_CR29","doi-asserted-by":"publisher","first-page":"954","DOI":"10.1136\/ard.2007.084459","volume":"68","author":"G Wells","year":"2009","unstructured":"Wells, G. et al. Validation of the 28-joint Disease Activity Score (DAS28) and European League Against Rheumatism response criteria based on C-reactive protein against disease progression in patients with rheumatoid arthritis, and comparison with the DAS28 based on erythrocyte sedimentation rate. Ann. Rheum. Dis. 68, 954\u2013960 (2009).","journal-title":"Ann. Rheum. Dis."},{"key":"54546_CR30","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1002\/art.1780380107","volume":"38","author":"ML Prevoo","year":"1995","unstructured":"Prevoo, M. L. et al. Modified disease activity scores that include twenty-eight-joint counts. Development and validation in a prospective longitudinal study of patients with rheumatoid arthritis. Arthritis Rheum. 38, 44\u201348 (1995).","journal-title":"Arthritis Rheum."},{"key":"54546_CR31","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1186\/1471-2105-13-134","volume":"13","author":"J Ye","year":"2012","unstructured":"Ye, J. et al. Primer-BLAST: A tool to design target-specific primers for polymerase chain reaction. BMC Bioinform. 13, 134 (2012).","journal-title":"BMC Bioinform."},{"key":"54546_CR32","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbc.2023.104778","volume":"299","author":"C Carico","year":"2023","unstructured":"Carico, C., Cui, J., Acton, A. & Placzek, W. J. Polypyrimidine tract binding protein 1 (PTBP1) contains a novel regulatory sequence, the rBH3, that binds the prosurvival protein MCL1. J. Biol. Chem. 299, 104778 (2023).","journal-title":"J. Biol. Chem."},{"key":"54546_CR33","doi-asserted-by":"crossref","unstructured":"Monz\u00f3n-Casanova, E. et al. Polypyrimidine tract-binding proteins are essential for B cell development. eLife 9, e53557 (2020).","DOI":"10.7554\/eLife.53557"},{"key":"54546_CR34","doi-asserted-by":"publisher","DOI":"10.1016\/j.coph.2022.102304","volume":"67","author":"V Tsaltskan","year":"2022","unstructured":"Tsaltskan, V. & Firestein, G. S. Targeting fibroblast-like synoviocytes in Rheumatoid Arthritis. Curr. Opin. Pharmacol. 67, 102304 (2022).","journal-title":"Curr. Opin. Pharmacol."},{"key":"54546_CR35","doi-asserted-by":"publisher","first-page":"1055","DOI":"10.1136\/annrheumdis-2021-222021","volume":"81","author":"T N\u00e9meth","year":"2022","unstructured":"N\u00e9meth, T., Nagy, G. & Pap, T. Synovial fibroblasts as potential drug targets in Rheumatoid Arthritis, where do we stand and where shall we go?. Ann. Rheum. Dis. 81, 1055\u20131064 (2022).","journal-title":"Ann. Rheum. Dis."},{"key":"54546_CR36","doi-asserted-by":"publisher","first-page":"e179392","DOI":"10.1172\/jci.insight.179392","volume":"9","author":"E Choi","year":"2024","unstructured":"Choi, E. et al. Joint-specific rheumatoid arthritis fibroblast-like synoviocyte regulation identified by integration of chromatin access and transcriptional activity. JCI Insight 9, e179392. https:\/\/doi.org\/10.1172\/jci.insight.179392 (2024).","journal-title":"JCI Insight"},{"key":"54546_CR37","doi-asserted-by":"publisher","first-page":"316","DOI":"10.1038\/s41584-020-0413-5","volume":"16","author":"G Nygaard","year":"2020","unstructured":"Nygaard, G. & Firestein, G. S. Restoring synovial homeostasis in Rheumatoid Arthritis by targeting fibroblast-like synoviocytes. Nat Rev Rheumatol 16, 316\u2013333 (2020).","journal-title":"Nat Rev Rheumatol"},{"key":"54546_CR38","doi-asserted-by":"publisher","first-page":"1260839","DOI":"10.3389\/fimmu.2023.1260839","volume":"14","author":"H Zhao","year":"2023","unstructured":"Zhao, H. et al. Ferroptosis as an emerging target in rheumatoid arthritis. Front. Immunol. 14, 1260839. https:\/\/doi.org\/10.3389\/fimmu.2023.1260839 (2023).","journal-title":"Front. Immunol."},{"key":"54546_CR39","doi-asserted-by":"publisher","first-page":"583","DOI":"10.1186\/s12935-021-02292-1","volume":"21","author":"Q Chu","year":"2021","unstructured":"Chu, Q. et al. Long noncoding RNA SNHG4: a novel target in human diseases. Cancer Cell Int. 21, 583 (2021).","journal-title":"Cancer Cell Int."},{"key":"54546_CR40","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s12276-019-0267-6","volume":"51","author":"M Bonelli","year":"2019","unstructured":"Bonelli, M. et al. IRF1 is critical for the TNF-driven interferon response in rheumatoid fibroblast-like synoviocytes. Exp. Mol. Med. 51, 1\u201311 (2019).","journal-title":"Exp. Mol. Med."},{"key":"54546_CR41","doi-asserted-by":"publisher","DOI":"10.3390\/ijms241813947","volume":"24","author":"S Perisset","year":"2023","unstructured":"Perisset, S., Potilinski, M. C. & Gallo, J. E. Role of Lnc-RNAs in the pathogenesis and development of diabetic retinopathy. Int. J. Mol. Sci. 24, 13947 (2023).","journal-title":"Int. J. Mol. Sci."},{"key":"54546_CR42","doi-asserted-by":"publisher","DOI":"10.1186\/s13075-022-02880-0","volume":"24","author":"Y Du","year":"2022","unstructured":"Du, Y. et al. Regulation of type I interferon signature by VGLL3 in the fibroblast-like synoviocytes of rheumatoid arthritis patients via targeting the Hippo pathway. Arthritis Res. Ther. 24, 188 (2022).","journal-title":"Arthritis Res. Ther."},{"key":"54546_CR43","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1007\/s10238-025-01567-5","volume":"25","author":"Z Liu","year":"2025","unstructured":"Liu, Z., Xu, H. & Chen, Z. The double-edged sword of lncRNAs in rheumatoid arthritis: from controlling the disease to its progress. Clin. Exp. Med. 25, 76 (2025).","journal-title":"Clin. Exp. Med."},{"key":"54546_CR44","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1111\/j.0105-2896.2009.00859.x","volume":"233","author":"B Bartok","year":"2010","unstructured":"Bartok, B. & Firestein, G. S. Fibroblast-like synoviocytes: Key effector cells in rheumatoid arthritis. Immunol. Rev. 233, 233\u2013255 (2010).","journal-title":"Immunol. Rev."},{"key":"54546_CR45","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtemb.2021.126712","volume":"65","author":"R Weiskirchen","year":"2021","unstructured":"Weiskirchen, R. & Penning, L. C. COMMD1, a multi-potent intracellular protein involved in copper homeostasis, protein trafficking, inflammation, and cancer. J. Trace Elem. Med. Biol. 65, 126712 (2021).","journal-title":"J. Trace Elem. Med. Biol."},{"key":"54546_CR46","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1186\/s13317-020-00135-z","volume":"11","author":"L Nejatbakhsh Samimi","year":"2020","unstructured":"Nejatbakhsh Samimi, L. et al. NF-\u03baB signaling in rheumatoid arthritis with focus on fibroblast-like synoviocytes. Auto Immun. Highlights. 11, 11 (2020).","journal-title":"Auto Immun. Highlights"},{"key":"54546_CR47","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1248\/bpb.b21-00574","volume":"45","author":"M Wang","year":"2022","unstructured":"Wang, M., Xie, Y., Shao, Y. & Chen, Y. LncRNA Snhg5 Attenuates Status Epilepticus Induced Inflammation through Regulating NF-\u03ba\u0392 Signaling Pathway. Biol. Pharm. Bull. 45, 86\u201393 (2022).","journal-title":"Biol. Pharm. Bull."},{"key":"54546_CR48","doi-asserted-by":"publisher","first-page":"1273933","DOI":"10.3389\/fgene.2023.1273933","volume":"14","author":"X Zhang","year":"2023","unstructured":"Zhang, X. et al. The emerging role of lncRNAs in osteoarthritis development and potential therapy. Front. Genet. 14, 1273933. https:\/\/doi.org\/10.3389\/fgene.2023.1273933 (2023).","journal-title":"Front. Genet."},{"key":"54546_CR49","doi-asserted-by":"publisher","first-page":"514","DOI":"10.1111\/j.1600-0854.2009.00892.x","volume":"10","author":"PAJ Muller","year":"2009","unstructured":"Muller, P. A. J. et al. Nuclear-cytosolic transport of COMMD1 regulates NF-kappaB and HIF-1 activity. Traffic 10, 514\u2013527 (2009).","journal-title":"Traffic"},{"key":"54546_CR50","doi-asserted-by":"publisher","first-page":"841","DOI":"10.1038\/cdd.2015.147","volume":"23","author":"D-W Yeh","year":"2016","unstructured":"Yeh, D-W. et al. Downregulation of COMMD1 by miR-205 promotes a positive feedback loop for amplifying inflammatory- and stemness-associated properties of cancer cells. Cell. Death Differ. 23, 841\u2013852 (2016).","journal-title":"Cell. Death Differ."},{"key":"54546_CR51","doi-asserted-by":"publisher","DOI":"10.1080\/15412555.2024.2363630","volume":"21","author":"X-T Yao","year":"2024","unstructured":"Yao, X.-T., Feng, W.-P., Gong, Z.-P. & Li, X.-P. Clinical significance of long non-coding RNA SNHG5 in the diagnosis and prognosis of chronic obstructive pulmonary disease. COPD 21, 2363630 (2024).","journal-title":"COPD"}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41598-026-54546-5","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-026-54546-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-026-54546-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T23:52:15Z","timestamp":1786060335000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41598-026-54546-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,28]]},"references-count":51,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["54546"],"URL":"https:\/\/doi.org\/10.1038\/s41598-026-54546-5","relation":{},"ISSN":["2045-2322"],"issn-type":[{"value":"2045-2322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,28]]},"assertion":[{"value":"31 December 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 May 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 May 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The study was approved by the Bioethics Committee of the University of Rzeszow (No. 9\/11\/2020) and conducted in accordance with the Declaration of Helsinki.","order":2,"name":"Ethics","label":"Institutional review board statement","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Informed consent was obtained from all subjects involved in the study.","order":3,"name":"Ethics","label":"Informed consent statement","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"24425"}}