{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T23:52:54Z","timestamp":1785887574343,"version":"3.56.0"},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T00:00:00Z","timestamp":1779753600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T00:00:00Z","timestamp":1785888000000},"content-version":"vor","delay-in-days":71,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"name":"Sumitomo Riko Co., Ltd."}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"DOI":"10.1038\/s41598-026-55010-0","type":"journal-article","created":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T18:52:27Z","timestamp":1779821547000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Effect of route familiarity on attentional resource allocation during real-world road driving"],"prefix":"10.1038","volume":"16","author":[{"given":"Damee","family":"Choi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuji","family":"Takeda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Motoyuki","family":"Akamatsu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaru","family":"Murayama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tetsuyoshi","family":"Shibata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masanori","family":"Yamamoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kensuke","family":"Sasai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,5,26]]},"reference":[{"key":"55010_CR1","unstructured":"Peden, M. World report on road traffic injury prevention (World Health Organization, 2004)."},{"issue":"1","key":"55010_CR2","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1186\/s12889-022-12880-w","volume":"22","author":"R Fisa","year":"2022","unstructured":"Fisa, R., Musukuma, M., Sampa, M., Musonda, P. & Young, T. Effects of interventions for preventing road traffic crashes: An overview of systematic reviews. BMC Public. Health. 22 (1), 513. https:\/\/doi.org\/10.1186\/s12889-022-12880-w (2022).","journal-title":"BMC Public. Health"},{"key":"55010_CR3","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1016\/j.trpro.2020.03.057","volume":"45","author":"K Bucsuh\u00e1zy","year":"2020","unstructured":"Bucsuh\u00e1zy, K. et al. Human factors contributing to the road traffic accident occurrence. Transp. Res. Procedia. 45, 555\u2013561. https:\/\/doi.org\/10.1016\/j.trpro.2020.03.057 (2020).","journal-title":"Transp. Res. Procedia"},{"issue":"10","key":"55010_CR4","doi-asserted-by":"publisher","first-page":"2636","DOI":"10.1073\/pnas.1513271113","volume":"113","author":"TA Dingus","year":"2016","unstructured":"Dingus, T. A. et al. Driver crash risk factors and prevalence evaluation using naturalistic driving data. Proc. Natl. Acad. Sci. 113 (10), 2636\u20132641. https:\/\/doi.org\/10.1073\/pnas.1513271113 (2016).","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"9","key":"55010_CR5","doi-asserted-by":"publisher","first-page":"819","DOI":"10.1023\/A:1007649804201","volume":"16","author":"E Petridou","year":"2000","unstructured":"Petridou, E. & Moustaki, M. Human factors in the causation of road traffic crashes. Eur. J. Epidemiol. 16 (9), 819\u2013826. https:\/\/doi.org\/10.1023\/A:1007649804201 (2000).","journal-title":"Eur. J. Epidemiol."},{"key":"55010_CR6","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1016\/j.trf.2013.03.008","volume":"19","author":"SG Charlton","year":"2013","unstructured":"Charlton, S. G. & Starkey, N. J. Driving on familiar roads: Automaticity and inattention blindness. Transp. Res. Part. F: Traffic Psychol. Behav. 19, 121\u2013133. https:\/\/doi.org\/10.1016\/j.trf.2013.03.008 (2013).","journal-title":"Transp. Res. Part. F: Traffic Psychol. Behav."},{"issue":"6","key":"55010_CR7","doi-asserted-by":"publisher","first-page":"476","DOI":"10.1016\/j.trf.2007.05.003","volume":"10","author":"MH Martens","year":"2007","unstructured":"Martens, M. H. & Fox, M. R. Do familiarity and expectations change perception? Drivers\u2019 glances and response to changes. Transp. Res. Part. F: Traffic Psychol. Behav. 10 (6), 476\u2013492. https:\/\/doi.org\/10.1016\/j.trf.2007.05.003 (2007).","journal-title":"Transp. Res. Part. F: Traffic Psychol. Behav."},{"key":"55010_CR8","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1016\/j.aap.2013.04.003","volume":"57","author":"MR Yanko","year":"2013","unstructured":"Yanko, M. R. & Spalek, T. M. Route familiarity breeds inattention: A driving simulator study. Accid. Anal. Prev. 57, 80\u201386. https:\/\/doi.org\/10.1016\/j.aap.2013.04.003 (2013).","journal-title":"Accid. Anal. Prev."},{"issue":"4","key":"55010_CR9","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1136\/ip.2004.006767","volume":"11","author":"IG Chen","year":"2005","unstructured":"Chen, I. G., Durbin, D. R., Elliott, M. R., Kallan, M. J. & Winston, F. K. Trip characteristics of vehicle crashes involving child passengers. Inj. Prev. 11 (4), 219\u2013224. https:\/\/doi.org\/10.1136\/ip.2004.006767 (2005).","journal-title":"Inj. Prev."},{"key":"55010_CR10","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.ssci.2017.04.009","volume":"98","author":"BR Burdett","year":"2017","unstructured":"Burdett, B. R., Starkey, N. J. & Charlton, S. G. The close to home effect in road crashes. Saf. Sci. 98, 1\u20138. https:\/\/doi.org\/10.1016\/j.ssci.2017.04.009 (2017).","journal-title":"Saf. Sci."},{"key":"55010_CR11","unstructured":"Kahneman, D. Attention and effort (Prentice Hall, 1973)."},{"key":"55010_CR12","unstructured":"Mullen, N., Charlton, J., Devlin, A. & Bedard, M. Simulator validity: Behaviours observed on the simulator and on the road. In Handbook of driving simulation for engineering, medicine and psychology 1\u201318 (CRC, 2011)."},{"issue":"2","key":"55010_CR13","doi-asserted-by":"publisher","first-page":"e0247373","DOI":"10.1371\/journal.pone.0247373","volume":"16","author":"E Gemonet","year":"2021","unstructured":"Gemonet, E., Bougard, C., Masfrand, S., Honnet, V. & Mestre, D. R. Car drivers coping with hazardous events in real versus simulated situations: Declarative, behavioral and physiological data used to assess drivers\u2019 feeling of presence. PLoS one. 16 (2), e0247373. https:\/\/doi.org\/10.1371\/journal.pone.0247373 (2021).","journal-title":"PLoS one"},{"key":"55010_CR14","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1016\/j.trf.2022.02.009","volume":"86","author":"M Kimura","year":"2022","unstructured":"Kimura, M., Kimura, K. & Takeda, Y. Assessment of driver\u2019s attentional resource allocation to visual, cognitive, and action processing by brain and eye signals. Transp. Res. Part. F: Traffic Psychol. Behav. 86, 161\u2013177. https:\/\/doi.org\/10.1016\/j.trf.2022.02.009 (2022).","journal-title":"Transp. Res. Part. F: Traffic Psychol. Behav."},{"issue":"3","key":"55010_CR15","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1016\/S0167-8760(00)00185-9","volume":"40","author":"Y Takeda","year":"2001","unstructured":"Takeda, Y., Sugai, M. & Yagi, A. Eye fixation related potentials in a proofreading task. Int. J. Psychophysiol. 40 (3), 181\u2013186. https:\/\/doi.org\/10.1016\/S0167-8760(00)00185-9 (2001).","journal-title":"Int. J. Psychophysiol."},{"issue":"6","key":"55010_CR16","doi-asserted-by":"publisher","first-page":"604","DOI":"10.1016\/0013-4694(81)91434-6","volume":"52","author":"A Yagi","year":"1981","unstructured":"Yagi, A. Visual signal detection and lambda responses. Electroencephalogr. Clin. Neurophysiol. 52 (6), 604\u2013610. https:\/\/doi.org\/10.1016\/0013-4694(81)91434-6 (1981).","journal-title":"Electroencephalogr. Clin. Neurophysiol."},{"key":"55010_CR17","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1016\/j.trf.2016.07.008","volume":"42","author":"Y Takeda","year":"2016","unstructured":"Takeda, Y. et al. Electrophysiological evaluation of attention in drivers and passengers: Toward an understanding of drivers\u2019 attentional state in autonomous vehicles. Transp. Res. Part. F: Traffic Psychol. Behav. 42, 140\u2013150. https:\/\/doi.org\/10.1016\/j.trf.2016.07.008 (2016b).","journal-title":"Transp. Res. Part. F: Traffic Psychol. Behav."},{"key":"55010_CR18","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1016\/j.biopsycho.2015.03.017","volume":"108","author":"H Wiberg","year":"2015","unstructured":"Wiberg, H., Nilsson, E., Lind\u00e9n, P., Svanberg, B. & Poom, L. Physiological responses related to moderate mental load during car driving in field conditions. Biol. Psychol. 108, 115\u2013125. https:\/\/doi.org\/10.1016\/j.biopsycho.2015.03.017 (2015).","journal-title":"Biol. Psychol."},{"issue":"1\u20132","key":"55010_CR19","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1016\/0301-0511(95)05108-2","volume":"40","author":"AF Kramer","year":"1995","unstructured":"Kramer, A. F., Trejo, L. J. & Humphrey, D. Assessment of mental workload with task-irrelevant auditory probes. Biol. Psychol. 40 (1\u20132), 83\u2013100. https:\/\/doi.org\/10.1016\/0301-0511(95)05108-2 (1995).","journal-title":"Biol. Psychol."},{"key":"55010_CR20","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1016\/j.biopsycho.2016.09.009","volume":"120","author":"Y Takeda","year":"2016","unstructured":"Takeda, Y., Inoue, K., Kimura, M., Sato, T. & Nagai, C. Electrophysiological assessment of driving pleasure and difficulty using a task-irrelevant probe technique. Biol. Psychol. 120, 137\u2013141. https:\/\/doi.org\/10.1016\/j.biopsycho.2016.09.009 (2016a).","journal-title":"Biol. Psychol."},{"issue":"2","key":"55010_CR21","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1017\/S0140525X00078407","volume":"13","author":"R N\u00e4\u00e4t\u00e4nen","year":"1990","unstructured":"N\u00e4\u00e4t\u00e4nen, R. The role of attention in auditory information processing as revealed by event-related potentials and other brain measures of cognitive function. Behav. Brain Sci. 13 (2), 201\u2013233. https:\/\/doi.org\/10.1017\/S0140525X00078407 (1990).","journal-title":"Behav. Brain Sci."},{"issue":"6","key":"55010_CR22","doi-asserted-by":"publisher","first-page":"464","DOI":"10.1016\/0013-4694(91)90166-2","volume":"79","author":"J Rif","year":"1991","unstructured":"Rif, J., Hari, R., H\u00e4m\u00e4l\u00e4inen, M. S. & Sams, M. Auditory attention affects two different areas in the human supratemporal cortex. Electroencephalogr. Clin. Neurophysiol. 79 (6), 464\u2013472. https:\/\/doi.org\/10.1016\/0013-4694(91)90166-2 (1991).","journal-title":"Electroencephalogr. Clin. Neurophysiol."},{"issue":"5","key":"55010_CR23","doi-asserted-by":"publisher","first-page":"590","DOI":"10.1162\/089892998562997","volume":"10","author":"C Escera","year":"1998","unstructured":"Escera, C., Alho, K., Winkler, I. & N\u00e4\u00e4t\u00e4nen, R. Neural mechanisms of involuntary attention to acoustic novelty and change. J. Cogn. Neurosci. 10 (5), 590\u2013604. https:\/\/doi.org\/10.1162\/089892998562997 (1998).","journal-title":"J. Cogn. Neurosci."},{"issue":"3","key":"55010_CR24","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1007\/s00421-003-0807-5","volume":"89","author":"PP Caffier","year":"2003","unstructured":"Caffier, P. P., Erdmann, U. & Ullsperger, P. Experimental evaluation of eye-blink parameters as a drowsiness measure. Eur. J. Appl. Physiol. 89 (3), 319\u2013325. https:\/\/doi.org\/10.1007\/s00421-003-0807-5 (2003).","journal-title":"Eur. J. Appl. Physiol."},{"issue":"3","key":"55010_CR25","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1016\/0301-0511(95)05166-X","volume":"42","author":"TL Morris","year":"1996","unstructured":"Morris, T. L. & Miller, J. C. Electrooculographic and performance indices of fatigue during simulated flight. Biol. Psychol. 42 (3), 343\u2013360. https:\/\/doi.org\/10.1016\/0301-0511(95)05166-X (1996).","journal-title":"Biol. Psychol."},{"issue":"7","key":"55010_CR26","doi-asserted-by":"publisher","first-page":"982","DOI":"10.1080\/00140130701817062","volume":"51","author":"R Schleicher","year":"2008","unstructured":"Schleicher, R., Galley, N., Briest, S. & Galley, L. Blinks and saccades as indicators of fatigue in sleepiness warnings: Looking tired? Ergonomics 51 (7), 982\u20131010. https:\/\/doi.org\/10.1080\/00140130701817062 (2008).","journal-title":"Ergonomics"},{"key":"55010_CR27","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1016\/j.aap.2019.01.013","volume":"124","author":"Y Wu","year":"2019","unstructured":"Wu, Y. et al. Effects of scheduled manual driving on drowsiness and response to take-over request: A simulator study towards understanding drivers in automated driving. Accid. Anal. Prev. 124, 202\u2013209. https:\/\/doi.org\/10.1016\/j.aap.2019.01.013 (2019).","journal-title":"Accid. Anal. Prev."},{"key":"55010_CR28","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1016\/j.jsr.2019.12.019","volume":"72","author":"Y Wu","year":"2020","unstructured":"Wu, Y. et al. Age-related differences in effects of non-driving-related tasks on takeover performance in automated driving. J. Saf. Res. 72, 231\u2013238. https:\/\/doi.org\/10.1016\/j.jsr.2019.12.019 (2020).","journal-title":"J. Saf. Res."},{"key":"55010_CR29","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1016\/j.trf.2021.06.017","volume":"81","author":"Y Wu","year":"2021","unstructured":"Wu, Y. et al. Eye movements predict driver reaction time to takeover request in automated driving: A real-vehicle study. Transp. Res. part. F: traffic Psychol. Behav. 81, 355\u2013363 (2021).","journal-title":"Transp. Res. part. F: traffic Psychol. Behav."},{"issue":"4","key":"55010_CR30","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1007\/s00221-010-2530-x","volume":"208","author":"S Cloete","year":"2011","unstructured":"Cloete, S. & Wallis, G. Visuomotor control of steering: The artefact of the matter. Exp. Brain Res. 208 (4), 475\u2013489. https:\/\/doi.org\/10.1007\/s00221-010-2530-x (2011).","journal-title":"Exp. Brain Res."},{"key":"55010_CR31","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1016\/j.aap.2013.09.016","volume":"62","author":"HC Chu","year":"2014","unstructured":"Chu, H. C. Assessing factors causing severe injuries in crashes of high-deck buses in long-distance driving on freeways. Accid. Anal. Prev. 62, 130\u2013136. https:\/\/doi.org\/10.1016\/j.aap.2013.09.016 (2014).","journal-title":"Accid. Anal. Prev."},{"issue":"3","key":"55010_CR32","doi-asserted-by":"publisher","first-page":"448","DOI":"10.1016\/j.physbeh.2008.02.015","volume":"94","author":"PH Ting","year":"2008","unstructured":"Ting, P. H., Hwang, J. R., Doong, J. L. & Jeng, M. C. Driver fatigue and highway driving: A simulator study. Physiol. Behav. 94 (3), 448\u2013453. https:\/\/doi.org\/10.1016\/j.physbeh.2008.02.015 (2008).","journal-title":"Physiol. Behav."},{"key":"55010_CR33","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1016\/j.trf.2018.08.009","volume":"59","author":"HE Walker","year":"2018","unstructured":"Walker, H. E. & Trick, L. M. Mind-wandering while driving: The impact of fatigue, task length, and sustained attention abilities. Transp. Res. Part. F: Traffic Psychol. Behav. 59, 81\u201397. https:\/\/doi.org\/10.1016\/j.trf.2018.08.009 (2018).","journal-title":"Transp. Res. Part. F: Traffic Psychol. Behav."},{"key":"55010_CR34","unstructured":"Kerr, J. S. Driving without attention mode (DWAM): A formalisation of inattentive states in driving. In (eds Gale, A. G. et al.) Vision in Vehicles III, 473\u2013479 (Elsevier, 1991)."},{"key":"55010_CR35","unstructured":"Wertheim, A. H. Highway hypnosis: A theoretical analysis. In (eds Gale, A. G. et al.) Vision in Vehicles III 467\u2013472 (Elsevier, 1991)."},{"key":"55010_CR36","doi-asserted-by":"publisher","first-page":"103179","DOI":"10.1016\/j.apergo.2020.103179","volume":"88","author":"F Sugimoto","year":"2020","unstructured":"Sugimoto, F. et al. Effects of one-pedal automobile operation on the driver\u2019s emotional state and cognitive workload. Appl. Ergon. 88, 103179. https:\/\/doi.org\/10.1016\/j.apergo.2020.103179 (2020).","journal-title":"Appl. Ergon."},{"issue":"1","key":"55010_CR37","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1016\/j.ijpsycho.2014.07.007","volume":"94","author":"Y Takeda","year":"2014","unstructured":"Takeda, Y. & Kimura, M. The auditory N1 amplitude for task-irrelevant probes reflects visual interest. Int. J. Psychophysiol. 94 (1), 35\u201341. https:\/\/doi.org\/10.1016\/j.ijpsycho.2014.07.007 (2014).","journal-title":"Int. J. Psychophysiol."},{"issue":"1","key":"55010_CR38","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1016\/j.jneumeth.2003.10.009","volume":"134","author":"A Delorme","year":"2004","unstructured":"Delorme, A. & Makeig, S. EEGLAB: An open source toolbox for analysis of single-trial EEG dynamics including independent component analysis. J. Neurosci. Methods. 134 (1), 9\u201321. https:\/\/doi.org\/10.1016\/j.jneumeth.2003.10.009 (2004).","journal-title":"J. Neurosci. Methods"},{"issue":"7","key":"55010_CR39","doi-asserted-by":"publisher","first-page":"1574","DOI":"10.1016\/j.clinph.2006.03.011","volume":"117","author":"K Kaida","year":"2006","unstructured":"Kaida, K. et al. Validation of the Karolinska Sleepiness Scale against performance and EEG variables. Clin. Neurophysiol. 117 (7), 1574\u20131581. https:\/\/doi.org\/10.1016\/j.clinph.2006.03.011 (2006).","journal-title":"Clin. Neurophysiol."},{"issue":"1\u20132","key":"55010_CR40","doi-asserted-by":"publisher","first-page":"29","DOI":"10.3109\/00207459008994241","volume":"52","author":"T \u00c5kerstedt","year":"1990","unstructured":"\u00c5kerstedt, T. & Gillberg, M. Subjective and objective sleepiness in the active individual. Int. J. Neurosci. 52 (1\u20132), 29\u201337. https:\/\/doi.org\/10.3109\/00207459008994241 (1990).","journal-title":"Int. J. Neurosci."},{"key":"55010_CR41","unstructured":"Zijlstra, F. R. H. & Van Doorn, L. The construction of a scale to measure perceived effort. ISN 6105\/6107, NABS N10. (Delft University of Technology, 1985)."},{"key":"55010_CR42","unstructured":"Sato, T. et al. Controlling task demands while approaching intersections. In Proc. of European Conference on Human Centred Design for ITS 603\u2013613 (2010)."}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41598-026-55010-0","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-026-55010-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-026-55010-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T23:35:32Z","timestamp":1785886532000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41598-026-55010-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,26]]},"references-count":42,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["55010"],"URL":"https:\/\/doi.org\/10.1038\/s41598-026-55010-0","relation":{},"ISSN":["2045-2322"],"issn-type":[{"value":"2045-2322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,26]]},"assertion":[{"value":"19 December 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 May 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 May 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"24096"}}