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All procedures were conducted in accordance with the principles outlined in the 2013 Declaration of Helsinki. Written informed consent was obtained from all living participants prior to inclusion in the study, and patient data were pseudonymized to ensure privacy and confidentiality. Control group samples were collected postmortem in compliance with the Act of 1 July 2005 on the Collection, Storage, and Transplantation of Cells, Tissues, and Organs (Journal of Laws of 2020, item 2134). Tissue procurement was performed in accordance with applicable national regulations and under the approvals granted by the relevant Bioethics Committees. In addition, informed consent for postmortem tissue collection and research use of the obtained specimens was obtained from the deceased donors\u2019 next of kin\/legal representatives prior to sample collection\n                      10\n                      .","order":2,"name":"Ethics","label":"Ethics approval and consent to participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Written informed consent for publication of anonymized research data was obtained from all living participants included in the study. For postmortem control samples, consent for tissue collection and research use was obtained from the deceased donors\u2019 next of kin\/legal representatives in accordance with applicable ethical and legal requirements.","order":3,"name":"Ethics","label":"Consent for publication","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"25386"}}