{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T04:58:55Z","timestamp":1790312335719,"version":"4.1.0"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T00:00:00Z","timestamp":1782432000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T00:00:00Z","timestamp":1790035200000},"content-version":"vor","delay-in-days":88,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"KAKENHI","award":["24K12098"],"award-info":[{"award-number":["24K12098"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>In peripheral artery disease (PAD), monitoring of arterial stiffness is crucial as it helps in understanding and managing the condition appropriately. Currently, brachial-ankle pulse wave velocity (baPWV) is the most prevailing technique for disease monitoring due to its operational simplicity. However, this method may cause discomfort, particularly in vulnerable populations, due to cuff inflation during the measurement procedure. Therefore, we studied the applicability of a new cuff-free method for vascular assessment by performing remote photoplethysmography (rPPG) using video recorded with an RGB camera. The pulse detected by the rPPG method reflects the density of red blood cells in the superficial layer of the skin, and can be used to estimate the heart rate. As a result of comparing the pulse of rPPG method and that of preexisting blood pressure monitors on the basis of R-peak of ECG, a significant correlation was found between the two.\u00a0Furthermore, we found a significant negative correlation between rPPG-PWV, based on the difference in pulse wave arrival times between the palm and sole, and preexisting baPWV. This result suggests that rPPG-PWV may be used as a substitute for baPWV.<\/jats:p>","DOI":"10.1038\/s41598-026-59922-9","type":"journal-article","created":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T07:43:28Z","timestamp":1782459808000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Development of a novel cuff-free method for monitoring arterial stiffness using remote photoplethysmography (rPPG)"],"prefix":"10.1038","volume":"16","author":[{"given":"Jun","family":"Hiraoka","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masato","family":"Takahashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeshi","family":"Yamaguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akihiro","family":"Ito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norimichi","family":"Tsumura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norio","family":"Iijima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,6,26]]},"reference":[{"key":"59922_CR1","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1161\/CIRCULATIONAHA.106.174526","volume":"113","author":"AT Hirsch","year":"2006","unstructured":"Hirsch, A. T. et al. ACC\/AHA 2005 Practice Guidelines for the management of patients with peripheral arterial disease (lower extremity, renal, mesenteric, and abdominal aortic): A collaborative report from the American Association for Vascular Surgery\/Society for Vascular Surgery, Society for Cardiovascular Angiography and Interventions, Society for Vascular Medicine and Biology, Society of Interventional Radiology, and the ACC\/AHA Task Force on Practice Guidelines (Writing Committee to Develop Guidelines for the Management of Patients With Peripheral Arterial Disease). Circulation 113, 463\u2013654 (2006).","journal-title":"Circulation"},{"key":"59922_CR2","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1016\/j.ejvs.2017.07.018","volume":"55","author":"V Aboyans","year":"2018","unstructured":"Aboyans, V. et al. 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Participants whose images were published provided written, informed consent for the images to be published in an online, open-access journal. This study was approved by the Ethics Review Committee of the International University of Health and Welfare (approval number: 23-Io-18).","order":2,"name":"Ethics","label":"Ethics approval","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"29412"}}