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This was in addition, to two cinnamic acid derivatives named as\n                    <jats:italic>E<\/jats:italic>\n                    -caffeic acid 4-\n                    <jats:italic>O<\/jats:italic>\n                    -\n                    <jats:italic>\u03b2<\/jats:italic>\n                    -\n                    <jats:bold>D<\/jats:bold>\n                    -\n                    <jats:sup>4<\/jats:sup>\n                    C\n                    <jats:sub>1\u2212<\/jats:sub>\n                    glucopranoside (\n                    <jats:bold>7<\/jats:bold>\n                    ) and\n                    <jats:italic>E<\/jats:italic>\n                    -caffeic acid (\n                    <jats:bold>8<\/jats:bold>\n                    ). Identification of the isolated compounds relied on their chromatographic properties and spectral data (UV, ESI-MS,\n                    <jats:sup>1<\/jats:sup>\n                    H NMR,\n                    <jats:sup>13<\/jats:sup>\n                    C NMR,\n                    <jats:sup>1<\/jats:sup>\n                    H-\n                    <jats:sup>1<\/jats:sup>\n                    H COSY, HSQC, and HMBC). The antischistosomal activity of the\n                    <jats:italic>C. madurensis<\/jats:italic>\n                    different extracts were assessed in vitro using schistosome worm killing, findings revealed that the aqueous methanol extract was the most effective extract, chromatographic fractionation of this extract revealed significant antischistosomal activity for fractions number V and VI rich in flavonoids and triterpene saponins, respectively.\n                  <\/jats:p>","DOI":"10.1038\/s41598-026-60749-7","type":"journal-article","created":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T08:15:37Z","timestamp":1783671337000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Chemical profile and in vitro antischistosomal activity of Crotalaria madurensis different extracts"],"prefix":"10.1038","volume":"16","author":[{"given":"Mona A.","family":"Mohamed","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samia","family":"William","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8398-1937","authenticated-orcid":false,"given":"Mosad A.","family":"Ghareeb","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanaa S.","family":"Botros","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,7,10]]},"reference":[{"key":"60749_CR1","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1111\/j.1365-2885.1980.tb00491.x","volume":"3","author":"N Nwude","year":"1980","unstructured":"Nwude, N. & Ibrahim, M. 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