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To further evaluate mice\u2019s cataplexy, we examined courtship behavior in orexin neuron-ablated mice (ORX-AB), one of the animal models of narcolepsy\/cataplexy. Wild-type female mice were placed into the home cage of male ORX-AB and cataplexy-like behavior was observed along with ultrasonic vocalizations (USVs), also known as the \u201clove song\u201d. ORX-AB with a female encounter showed cataplexy-like behavior both during the dark and light periods, whereas ORX-AB with chocolate predominantly showed it during the dark period. During the light period observation, more than 85% of cataplexy-like bouts were preceded by USVs. A strong positive correlation was observed between the number of USVs and cataplexy-like bouts. Cataplexy-like behavior in narcoleptic mice is a good behavioral measure to study the brain mechanisms behind positive emotion because they can be induced by different kinds of positive stimuli, including chocolate and female courtship.<\/jats:p>","DOI":"10.1038\/s42003-021-01696-z","type":"journal-article","created":{"date-parts":[[2021,2,5]],"date-time":"2021-02-05T11:38:05Z","timestamp":1612525085000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Sexual excitation induces courtship ultrasonic vocalizations and cataplexy-like behavior in orexin neuron-ablated male mice"],"prefix":"10.1038","volume":"4","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4226-3610","authenticated-orcid":false,"given":"Tomoyuki","family":"Kuwaki","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0061-6158","authenticated-orcid":false,"given":"Kouta","family":"Kanno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,2,5]]},"reference":[{"key":"1696_CR1","doi-asserted-by":"publisher","first-page":"383","DOI":"10.3758\/s13415-016-0414-7","volume":"16","author":"A Suardi","year":"2016","unstructured":"Suardi, A., Sotgiu, I., Costa, T., Cauda, F. & Rusconi, M. 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