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By visualizing murine Purkinje cells with different molecular identities, we demonstrate that the potential for induction of long-term depression is prominent in downbound and minimal in the upbound subpopulation. These differential propensities depend on the expression profile, but not on the synaptic inputs, of the individual Purkinje cell involved, highlighting the functional relevance of intrinsic properties for memory formation.<\/jats:p>","DOI":"10.1038\/s42003-022-04283-y","type":"journal-article","created":{"date-parts":[[2022,12,3]],"date-time":"2022-12-03T06:03:08Z","timestamp":1670047388000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Postsynaptic plasticity of Purkinje cells in mice is determined by molecular identity"],"prefix":"10.1038","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6113-6276","authenticated-orcid":false,"given":"Stijn","family":"Voerman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bastiaan H. 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