{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T18:53:35Z","timestamp":1780340015487,"version":"3.54.1"},"reference-count":52,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,12,31]],"date-time":"2024-12-31T00:00:00Z","timestamp":1735603200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2024,12,31]],"date-time":"2024-12-31T00:00:00Z","timestamp":1735603200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31672550"],"award-info":[{"award-number":["31672550"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Commun Biol"],"DOI":"10.1038\/s42003-024-07402-z","type":"journal-article","created":{"date-parts":[[2024,12,31]],"date-time":"2024-12-31T10:51:08Z","timestamp":1735642268000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Schistosoma sex-biased microRNAs regulate ovarian development and egg production by targeting Wnt signaling pathway"],"prefix":"10.1038","volume":"7","author":[{"given":"Pengfei","family":"Du","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianqi","family":"Xia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuxin","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bikash R.","family":"Giri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuantao","family":"Fang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shun","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shi","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5249-1065","authenticated-orcid":false,"given":"Guofeng","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,12,31]]},"reference":[{"key":"7402_CR1","doi-asserted-by":"publisher","first-page":"2253","DOI":"10.1016\/S0140-6736(13)61949-2","volume":"383","author":"DG Colley","year":"2014","unstructured":"Colley, D. G., Bustinduy, A. L., Secor, W. E. & King, C. H. Human schistosomiasis. Lancet 383, 2253\u20132264 (2014).","journal-title":"Lancet"},{"key":"7402_CR2","doi-asserted-by":"publisher","first-page":"e3000254","DOI":"10.1371\/journal.pbio.3000254","volume":"17","author":"J Wang","year":"2019","unstructured":"Wang, J., Chen, R. & Collins, J. J. 3rd. Systematically improved in vitro culture conditions reveal new insights into the reproductive biology of the human parasite Schistosoma mansoni. PLoS Biol. 17, e3000254 (2019).","journal-title":"PLoS Biol."},{"key":"7402_CR3","doi-asserted-by":"publisher","DOI":"10.1038\/srep31150","volume":"6","author":"Z Lu","year":"2016","unstructured":"Lu, Z. et al. Schistosome sex matters: a deep view into gonad-specific and pairing-dependent transcriptomes reveals a complex gender interplay. Sci. Rep. 6, 31150 (2016).","journal-title":"Sci. Rep."},{"key":"7402_CR4","doi-asserted-by":"publisher","first-page":"422","DOI":"10.1016\/j.mib.2009.06.005","volume":"12","author":"PT LoVerde","year":"2009","unstructured":"LoVerde, P. T., Andrade, L. F. & Oliveira, G. Signal transduction regulates schistosome reproductive biology. Curr. Opin. Microbiol. 12, 422\u2013428 (2009).","journal-title":"Curr. Opin. Microbiol."},{"key":"7402_CR5","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms14693","volume":"8","author":"J Wang","year":"2017","unstructured":"Wang, J. et al. Dynamic transcriptomes identify biogenic amines and insect-like hormonal regulation for mediating reproduction in Schistosoma japonicum. Nat. Commun. 8, 14693 (2017).","journal-title":"Nat. Commun."},{"key":"7402_CR6","doi-asserted-by":"publisher","first-page":"511","DOI":"10.1002\/pmic.200400953","volume":"5","author":"GF Cheng","year":"2005","unstructured":"Cheng, G. F. et al. Proteomic analysis of differentially expressed proteins between the male and female worm of Schistosoma japonicum after pairing. Proteomics 5, 511\u2013521 (2005).","journal-title":"Proteomics"},{"key":"7402_CR7","doi-asserted-by":"publisher","first-page":"868","DOI":"10.1016\/j.jprot.2011.10.003","volume":"75","author":"R Luo","year":"2012","unstructured":"Luo, R. et al. Identification of in vivo protein phosphorylation sites in human pathogen Schistosoma japonicum by a phosphoproteomic approach. J. Proteom. 75, 868\u2013877 (2012).","journal-title":"J. Proteom."},{"key":"7402_CR8","doi-asserted-by":"publisher","first-page":"e1005423","DOI":"10.1371\/journal.ppat.1005423","volume":"12","author":"L Zhu","year":"2016","unstructured":"Zhu, L. et al. MicroRNAs are involved in the regulation of ovary development in the pathogenic blood fluke Schistosoma japonicum. PLoS Pathog. 12, e1005423 (2016).","journal-title":"PLoS Pathog."},{"key":"7402_CR9","doi-asserted-by":"publisher","first-page":"1506","DOI":"10.1016\/j.cell.2022.03.017","volume":"185","author":"R Chen","year":"2022","unstructured":"Chen, R. et al. A male-derived nonribosomal peptide pheromone controls female schistosome development. Cell 185, 1506\u20131520 e1517 (2022).","journal-title":"Cell"},{"key":"7402_CR10","doi-asserted-by":"publisher","first-page":"345","DOI":"10.1038\/nature08140","volume":"460","author":"Y Zhou","year":"2009","unstructured":"Zhou, Y. et al. The Schistosoma japonicum genome reveals features of host\u2013parasite interplay. Nature 460, 345\u2013351 (2009).","journal-title":"Nature"},{"key":"7402_CR11","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2164-12-215","volume":"12","author":"LF Andrade","year":"2011","unstructured":"Andrade, L. F. et al. Eukaryotic protein kinases (ePKs) of the helminth parasite Schistosoma mansoni. BMC Genomics 12, 215 (2011).","journal-title":"BMC Genomics"},{"key":"7402_CR12","doi-asserted-by":"publisher","first-page":"497","DOI":"10.1017\/S0031182010000053","volume":"137","author":"S Beckmann","year":"2010","unstructured":"Beckmann, S. et al. Schistosoma mansoni: signal transduction processes during the development of the reproductive organs. Parasitology 137, 497\u2013520 (2010).","journal-title":"Parasitology"},{"key":"7402_CR13","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1038\/s41580-018-0045-7","volume":"20","author":"LFR Gebert","year":"2019","unstructured":"Gebert, L. F. R. & MacRae, I. J. Regulation of microRNA function in animals. Nat. Rev. Mol. Cell Biol. 20, 21\u201337 (2019).","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"7402_CR14","doi-asserted-by":"publisher","first-page":"e2402","DOI":"10.1371\/journal.pntd.0002402","volume":"7","author":"A Marco","year":"2013","unstructured":"Marco, A. et al. Sex-biased expression of microRNAs in Schistosoma mansoni. PLoS Negl. Trop. Dis. 7, e2402 (2013).","journal-title":"PLoS Negl. Trop. Dis."},{"key":"7402_CR15","doi-asserted-by":"publisher","first-page":"767","DOI":"10.1016\/j.cell.2006.07.013","volume":"126","author":"BJ Thompson","year":"2006","unstructured":"Thompson, B. J. & Cohen, S. M. The Hippo pathway regulates the bantam microRNA to control cell proliferation and apoptosis in Drosophila. Cell 126, 767\u2013774 (2006).","journal-title":"Cell"},{"key":"7402_CR16","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1016\/S0092-8674(03)00231-9","volume":"113","author":"J Brennecke","year":"2003","unstructured":"Brennecke, J., Hipfner, D. R., Stark, A., Russell, R. B. & Cohen, S. M. bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila. Cell 113, 25\u201336 (2003).","journal-title":"Cell"},{"key":"7402_CR17","doi-asserted-by":"publisher","first-page":"1602","DOI":"10.1101\/gad.192021.112","volume":"26","author":"H Herranz","year":"2012","unstructured":"Herranz, H., Hong, X., Hung, N. T., Voorhoeve, P. M. & Cohen, S. M. Oncogenic cooperation between SOCS family proteins and EGFR identified using a Drosophila epithelial transformation model. Genes Dev. 26, 1602\u20131611 (2012).","journal-title":"Genes Dev."},{"key":"7402_CR18","doi-asserted-by":"publisher","first-page":"1688","DOI":"10.1038\/emboj.2010.69","volume":"29","author":"H Herranz","year":"2010","unstructured":"Herranz, H. et al. The miRNA machinery targets Mei-P26 and regulates Myc protein levels in the Drosophila wing. EMBO J. 29, 1688\u20131698 (2010).","journal-title":"EMBO J."},{"key":"7402_CR19","doi-asserted-by":"publisher","first-page":"3781","DOI":"10.1242\/dev.064774","volume":"138","author":"I Becam","year":"2011","unstructured":"Becam, I., Rafel, N., Hong, X., Cohen, S. M. & Milan, M. Notch-mediated repression of bantam miRNA contributes to boundary formation in the Drosophila wing. Development 138, 3781\u20133789 (2011).","journal-title":"Development"},{"key":"7402_CR20","doi-asserted-by":"publisher","first-page":"e201900381","DOI":"10.26508\/lsa.201900381","volume":"2","author":"SU Gerlach","year":"2019","unstructured":"Gerlach, S. U., Sander, M., Song, S. & Herranz, H. The miRNA bantam regulates growth and tumorigenesis by repressing the cell cycle regulator tribbles. Life Sci. Alliance 2, e201900381 (2019).","journal-title":"Life Sci. Alliance"},{"key":"7402_CR21","doi-asserted-by":"publisher","first-page":"651","DOI":"10.1016\/j.cub.2012.02.050","volume":"22","author":"H Herranz","year":"2012","unstructured":"Herranz, H., Hong, X. & Cohen, S. M. Mutual repression by bantam miRNA and Capicua links the EGFR\/MAPK and Hippo pathways in growth control. Curr. Biol. 22, 651\u2013657 (2012).","journal-title":"Curr. Biol."},{"key":"7402_CR22","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1111\/j.1525-142X.2008.00302.x","volume":"11","author":"BM Wheeler","year":"2009","unstructured":"Wheeler, B. M. et al. The deep evolution of metazoan microRNAs. Evol. Dev. 11, 50\u201368 (2009).","journal-title":"Evol. Dev."},{"key":"7402_CR23","doi-asserted-by":"publisher","first-page":"e64003","DOI":"10.1371\/journal.pone.0064003","volume":"8","author":"P Cai","year":"2013","unstructured":"Cai, P. et al. A deep analysis of the small non-coding RNA population in Schistosoma japonicum eggs. PLoS ONE 8, e64003 (2013).","journal-title":"PLoS ONE"},{"key":"7402_CR24","doi-asserted-by":"publisher","first-page":"e1256","DOI":"10.1371\/journal.pntd.0001256","volume":"5","author":"P Cai","year":"2011","unstructured":"Cai, P. et al. Profiles of small non-coding RNAs in Schistosoma japonicum during development. PLoS Negl. Trop. Dis. 5, e1256 (2011).","journal-title":"PLoS Negl. Trop. Dis."},{"key":"7402_CR25","doi-asserted-by":"publisher","first-page":"e596","DOI":"10.1371\/journal.pntd.0000596","volume":"4","author":"Z Wang","year":"2010","unstructured":"Wang, Z. et al. An \u201cin-depth\u201d description of the small non-coding RNA population of Schistosoma japonicum schistosomulum. PLoS Negl. Trop. Dis. 4, e596 (2010).","journal-title":"PLoS Negl. Trop. Dis."},{"key":"7402_CR26","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2164-11-55","volume":"11","author":"L Hao","year":"2010","unstructured":"Hao, L., Cai, P., Jiang, N., Wang, H. & Chen, Q. Identification and characterization of microRNAs and endogenous siRNAs in Schistosoma japonicum. BMC Genomics 11, 55 (2010).","journal-title":"BMC Genomics"},{"key":"7402_CR27","doi-asserted-by":"publisher","first-page":"e4034","DOI":"10.1371\/journal.pone.0004034","volume":"3","author":"X Xue","year":"2008","unstructured":"Xue, X. et al. Identification and characterization of novel microRNAs from Schistosoma japonicum. PLoS ONE 3, e4034 (2008).","journal-title":"PLoS ONE"},{"key":"7402_CR28","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1101\/gad.274027.115","volume":"30","author":"Z Meng","year":"2016","unstructured":"Meng, Z., Moroishi, T. & Guan, K. L. Mechanisms of Hippo pathway regulation. Genes Dev. 30, 1\u201317 (2016).","journal-title":"Genes Dev."},{"key":"7402_CR29","doi-asserted-by":"publisher","first-page":"68","DOI":"10.4161\/org.4.2.5851","volume":"4","author":"Y Komiya","year":"2008","unstructured":"Komiya, Y. & Habas, R. Wnt signal transduction pathways. Organogenesis 4, 68\u201375 (2008).","journal-title":"Organogenesis"},{"key":"7402_CR30","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1038\/nature01148","volume":"420","author":"S Etienne-Manneville","year":"2002","unstructured":"Etienne-Manneville, S. & Hall, A. Rho GTPases in cell biology. Nature 420, 629\u2013635 (2002).","journal-title":"Nature"},{"key":"7402_CR31","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1080\/21541248.2017.1294234","volume":"10","author":"M Denk-Lobnig","year":"2019","unstructured":"Denk-Lobnig, M. & Martin, A. C. Modular regulation of Rho family GTPases in development. Small GTPases 10, 122\u2013129 (2019).","journal-title":"Small GTPases"},{"key":"7402_CR32","doi-asserted-by":"crossref","unstructured":"He, X., Pu, G. B., Tang, R., Zhang, D. M. & Pan, W. Q. Activation of nuclear factor kappa B in the hepatic stellate cells of mice with schistosomiasis japonica (vol 9, e104323, 2014). PLoS ONE 15 (2020). https:\/\/doi.org\/ARTN e024366710.1371\/journal.pone.0243667","DOI":"10.1371\/journal.pone.0104323"},{"key":"7402_CR33","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1016\/j.gep.2011.01.002","volume":"11","author":"X Wang","year":"2011","unstructured":"Wang, X. et al. Characterization and expression of a novel Frizzled 9 gene in Schistosoma japonicum. Gene Expr. Patterns 11, 263\u2013270 (2011).","journal-title":"Gene Expr. Patterns"},{"key":"7402_CR34","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1016\/j.gep.2019.02.005","volume":"32","author":"Z Ye","year":"2019","unstructured":"Ye, Z. et al. Spatiotemporal expression pattern of Sjfz7 and its expression comparison with other frizzled family genes in developmental stages of Schistosoma japonicum. Gene Expr. Patterns 32, 44\u201352 (2019).","journal-title":"Gene Expr. Patterns"},{"key":"7402_CR35","doi-asserted-by":"publisher","first-page":"1192","DOI":"10.1016\/j.cell.2012.05.012","volume":"149","author":"H Clevers","year":"2012","unstructured":"Clevers, H. & Nusse, R. Wnt\/\u03b2-catenin signaling and disease. Cell 149, 1192\u20131205 (2012).","journal-title":"Cell"},{"key":"7402_CR36","doi-asserted-by":"publisher","first-page":"226","DOI":"10.1016\/j.tips.2016.11.009","volume":"38","author":"J Wu","year":"2017","unstructured":"Wu, J. et al. Heat shock proteins and cancer. Trends Pharm. Sci. 38, 226\u2013256 (2017).","journal-title":"Trends Pharm. Sci."},{"key":"7402_CR37","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/6610529","volume":"2021","author":"N Li","year":"2021","unstructured":"Li, N. et al. HSP60 regulates lipid metabolism in human ovarian cancer. Oxid. Med. Cell Longev. 2021, 6610529 (2021).","journal-title":"Oxid. Med. Cell Longev."},{"key":"7402_CR38","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1046\/j.1432-0436.1996.6030159.x","volume":"60","author":"J Paranko","year":"1996","unstructured":"Paranko, J., Seitz, J. & Meinhardt, A. Developmental expression of heat shock protein 60 (HSP60) in the rat testis and ovary. Differentiation 60, 159\u2013167 (1996).","journal-title":"Differentiation"},{"key":"7402_CR39","doi-asserted-by":"publisher","DOI":"10.5603\/FM.a2020.0126","author":"S Zou","year":"2021","unstructured":"Zou, S. et al. Hsp60 expression and localization in different tissues and testis development of male cattle (cattle-yak and yak). Folia Morphol. https:\/\/doi.org\/10.5603\/FM.a2020.0126 (2021).","journal-title":"Folia Morphol."},{"key":"7402_CR40","doi-asserted-by":"publisher","unstructured":"Fang, D. A. et al. Developmental expression of HSP60 and HSP10 in the Coilia nasus Testis during upstream spawning migration. Genes 8 (2017). https:\/\/doi.org\/10.3390\/genes8070189","DOI":"10.3390\/genes8070189"},{"key":"7402_CR41","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1017\/S0022149X11000447","volume":"86","author":"WN Zhang","year":"2012","unstructured":"Zhang, W. N. et al. Worm morphology of Schistosoma japonicum using confocal laser scanning microscopy. J. Helminthol. 86, 317\u2013322 (2012).","journal-title":"J. Helminthol."},{"key":"7402_CR42","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1038\/nmeth.3317","volume":"12","author":"D Kim","year":"2015","unstructured":"Kim, D., Langmead, B. & Salzberg, S. L. HISAT: a fast spliced aligner with low memory requirements. Nat. Methods 12, 357\u2013360 (2015).","journal-title":"Nat. Methods"},{"key":"7402_CR43","doi-asserted-by":"publisher","first-page":"290","DOI":"10.1038\/nbt.3122","volume":"33","author":"M Pertea","year":"2015","unstructured":"Pertea, M. et al. StringTie enables improved reconstruction of a transcriptome from RNA-seq reads. Nat. Biotechnol. 33, 290\u2013295 (2015).","journal-title":"Nat. Biotechnol."},{"key":"7402_CR44","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1093\/bioinformatics\/btp612","volume":"26","author":"L Wang","year":"2010","unstructured":"Wang, L., Feng, Z., Wang, X., Wang, X. & Zhang, X. DEGseq: an R package for identifying differentially expressed genes from RNA-seq data. Bioinformatics 26, 136\u2013138 (2010).","journal-title":"Bioinformatics"},{"key":"7402_CR45","doi-asserted-by":"publisher","DOI":"10.1186\/gb-2010-11-10-r106","volume":"11","author":"S Anders","year":"2010","unstructured":"Anders, S. & Huber, W. Differential expression analysis for sequence count data. Genome Biol. 11, R106 (2010).","journal-title":"Genome Biol."},{"key":"7402_CR46","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1006\/meth.2001.1262","volume":"25","author":"KJ Livak","year":"2001","unstructured":"Livak, K. J. & Schmittgen, T. D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25, 402\u2013408 (2001).","journal-title":"Methods"},{"key":"7402_CR47","doi-asserted-by":"publisher","first-page":"D204","DOI":"10.1093\/nar\/gkab1101","volume":"50","author":"B Fromm","year":"2022","unstructured":"Fromm, B. et al. MirGeneDB 2.1: toward a complete sampling of all major animal phyla. Nucleic Acids Res. 50, D204\u2013D210 (2022).","journal-title":"Nucleic Acids Res."},{"key":"7402_CR48","doi-asserted-by":"publisher","first-page":"1188","DOI":"10.1101\/gr.849004","volume":"14","author":"GE Crooks","year":"2004","unstructured":"Crooks, G. E., Hon, G., Chandonia, J. M. & Brenner, S. E. WebLogo: a sequence logo generator. Genome Res. 14, 1188\u20131190 (2004).","journal-title":"Genome Res."},{"key":"7402_CR49","doi-asserted-by":"publisher","first-page":"1507","DOI":"10.1261\/rna.5248604","volume":"10","author":"M Rehmsmeier","year":"2004","unstructured":"Rehmsmeier, M., Steffen, P., Hochsmann, M. & Giegerich, R. Fast and effective prediction of microRNA\/target duplexes. RNA 10, 1507\u20131517 (2004).","journal-title":"RNA"},{"key":"7402_CR50","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/gb-2003-5-1-r1","volume":"4","author":"A Enright","year":"2003","unstructured":"Enright, A. et al. MicroRNA targets in Drosophila. Genome Biol. 4, 1\u201327 (2003).","journal-title":"Genome Biol."},{"key":"7402_CR51","doi-asserted-by":"publisher","first-page":"809","DOI":"10.1080\/15476286.2019.1590177","volume":"16","author":"ZZ Zheng","year":"2019","unstructured":"Zheng, Z. Z. et al. Alternative splicingf regulation of doublesex gene by RNA-binding proteins in the silkworm Bombyx mori. RNA Biol. 16, 809\u2013820 (2019).","journal-title":"RNA Biol."},{"key":"7402_CR52","doi-asserted-by":"crossref","unstructured":"Daniel Gietz, R. & Woods, R. A. Transformation of yeast by lithium acetate\/single-stranded carrier DNA\/polyethylene glycol method. In Guide to Yeast Genetics and Molecular and Cell Biology - Part B Vol. 350 Methods in Enzymology (eds Guthrie, C. & Fink, G. R.) 87\u201396 (Academic Press, 2002).","DOI":"10.1016\/S0076-6879(02)50957-5"}],"container-title":["Communications Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s42003-024-07402-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s42003-024-07402-z","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s42003-024-07402-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,31]],"date-time":"2024-12-31T12:01:54Z","timestamp":1735646514000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s42003-024-07402-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12,31]]},"references-count":52,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["7402"],"URL":"https:\/\/doi.org\/10.1038\/s42003-024-07402-z","relation":{},"ISSN":["2399-3642"],"issn-type":[{"value":"2399-3642","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12,31]]},"assertion":[{"value":"22 April 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 December 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 December 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"1717"}}