{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T21:56:05Z","timestamp":1787003765786,"version":"build-2736575974"},"reference-count":36,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,2,28]],"date-time":"2024-02-28T00:00:00Z","timestamp":1709078400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,2,28]],"date-time":"2024-02-28T00:00:00Z","timestamp":1709078400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Commun Med"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The associations between deprivation and illness trajectory after hospitalisation for coronavirus disease-19 (COVID-19) are uncertain.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A prospective, multicentre cohort study was conducted on post-COVID-19 patients, enrolled either in-hospital or shortly post-discharge. Two evaluations were carried out: an initial assessment and a follow-up at 28\u201360 days post-discharge. The study encompassed research blood tests, patient-reported outcome measures, and multisystem imaging (including chest computed tomography (CT) with pulmonary and coronary angiography, cardiovascular and renal magnetic resonance imaging). Primary and secondary outcomes were analysed in relation to socioeconomic status, using the Scottish Index of Multiple Deprivation (SIMD). The EQ-5D-5L, Brief Illness Perception Questionnaire (BIPQ), Patient Health Questionnaire-4 (PHQ-4) for Anxiety and Depression, and the Duke Activity Status Index (DASI) were used to assess health status.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of the 252 enrolled patients (mean age 55.0\u2009\u00b1\u200912.0 years; 40% female; 23% with diabetes), deprivation status was linked with increased BMI and diabetes prevalence. 186 (74%) returned for the follow-up. Within this group, findings indicated associations between deprivation and lung abnormalities (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.0085), coronary artery disease (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.0128), and renal inflammation (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.0421). Furthermore, patients with higher deprivation exhibited worse scores in health-related quality of life (EQ-5D-5L,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.0084), illness perception (BIPQ,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.0004), anxiety and depression levels (PHQ-4,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.0038), and diminished physical activity (DASI,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.002). At the 3-month mark, those with greater deprivation showed a higher frequency of referrals to secondary care due to ongoing COVID-19 symptoms (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.0438). However, clinical outcomes were not influenced by deprivation.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In a post-hospital COVID-19 population, socioeconomic deprivation was associated with impaired health status and secondary care episodes. Deprivation influences illness trajectory after COVID-19.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1038\/s43856-024-00455-5","type":"journal-article","created":{"date-parts":[[2024,2,28]],"date-time":"2024-02-28T13:02:59Z","timestamp":1709125379000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Socioeconomic deprivation and illness trajectory in the Scottish population after COVID-19 hospitalization"],"prefix":"10.1038","volume":"4","author":[{"given":"Andrew 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