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Using regression models, we examined the association between biomarkers and sex, age, Body Mass Index (BMI), and smoking.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Here we show that concentrations of inflammation and vascular stress biomarkers generally increase with higher age, BMI, and smoking. Sex-specific effects are observed for multiple biomarkers.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>This study provides comprehensive information on concentrations of 47 plasma biomarkers in healthy individuals. The study emphasizes that knowledge about biomarker concentrations in healthy individuals is critical for improved understanding of disease pathology and for tailored care and decision support tools.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1038\/s43856-024-00474-2","type":"journal-article","created":{"date-parts":[[2024,3,16]],"date-time":"2024-03-16T14:01:44Z","timestamp":1710597704000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Lifestyle and demographic associations with 47 inflammatory and vascular stress biomarkers in 9876 blood 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