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Preprint at arXiv https:\/\/doi.org\/10.48550\/arXiv.2401.11817 (2025).","DOI":"10.48550\/arXiv.2401.11817"}],"container-title":["Communications Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s43856-026-01790-5","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s43856-026-01790-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s43856-026-01790-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,11,9]],"date-time":"2026-11-09T00:06:48Z","timestamp":1794182808000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s43856-026-01790-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,16]]},"references-count":53,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["1790"],"URL":"https:\/\/doi.org\/10.1038\/s43856-026-01790-5","relation":{},"ISSN":["2730-664X"],"issn-type":[{"value":"2730-664X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,16]]},"assertion":[{"value":"24 October 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 July 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 July 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"F.C. declares invited speaker for EVENTs Srl, Merck, Novartis, and Johnson & Johnson. L.M. declares conference grants from Sanofi, Daiichi Sankyo, LEOPharma; honoraria from Novartis, Merck Sharp and Dohme (MSD), Elma Research. V.M. declares speaker honorarium from Novartis. A.F. declares speaker honorarium from Novartis. L. Provenzano declares speaker honorarium from Novartis, Pfizer, and Gilead. A.S. declares speaker honorarium from Novartis, MSD, Bristol Myers Squibb (BMS), Immunocore, and Pierre Fabre. G.C. declares speaker honorarium from Takeda, conference grants from Amgen, and AstraZeneca. T.B. declares conference grants from MSD, Sanofi, Pfizer, Lilly; honoraria from MSD. M.O. declares consulting\/advisory role for AstraZeneca, BMS, MSD, Pfizer, J&J; honoraria from AstraZeneca, BMS, MSD; conference grants from Eli Lilly, Johnson & Johnson (J&J). M.Brambilla declares conference grants from Eli Lilly, J&J, LeoPharma, honoraria from BMS, and AstraZeneca. C.P. declares personal fees from Italfarmaco, AstraZeneca, BMS, Merck Sharp and Dohme, and Janssen; and institutional funding from Novartis. J.N.K. declares consulting services for Panakeia, AstraZeneca, MultiplexDx, Mindpeak, Owkin, DoMore Diagnostics, and Bioptimus. Furthermore, he holds shares in StratifAI, Synagen, Tremont AI, and Ignition Labs, has received an institutional research grant from GSK, and has received honoraria from AstraZeneca, Bayer, Daiichi Sankyo, Eisai, Janssen, MSD, BMS, Roche, Pfizer, and Fresenius. A.L.G.P. declares co-founder and shareholder of two startup companies, Agade srl and AllyArm srl; speaker honorarium from Novartis. F.d.B. declares a patent for PCT\/ IB2020\/055956 pending and a patent for IT201900009954 pending; honoraria from, or consultant role for, Roche, EMD Serono, Nerviano Medical Science (NMS), Sanofi, MSD, Novartis, Incyte, BMS, Menarini Healthcare Research & Pharmacoepidemiology, Merck Group, Pfizer, Servier, Applied Molecular Genetics (AMGEN), Incyte, outside the submitted work. G.L.R. declares consultant role for Roche, Novartis, BMS, MSD, AstraZeneca, Takeda, Amgen, Sanofi, Italfarmaco, Pfizer; payment or honoraria for lectures, presentations, speakers bureaus, manuscript writing or educational events from Roche, Novartis, BMS, MSD, AstraZeneca, Takeda, Amgen, Sanofi; support for attending meetings and\/or travel from Roche, BMS, MSD; data safety monitoring board or advisory board for Roche, Novartis, BMS, MSD, AstraZeneca, Sanofi; has acted as principal investigator in sponsored clinical trials for Roche, Novartis, BMS, MSD, AstraZeneca, GlaxoSmithKline (GSK), Amgen, Sanofi, outside the submitted work. A.P. declares consulting\/advisory role for BMS, AstraZeneca, Novartis; travel, accommodations, or other expenses paid or reimbursed by Roche, Italfarmaco; principal investigator of Spectrum Pharmaceuticals; personal fees from Roche, AstraZeneca, and BMS, outside the submitted work. V.P., G.L., L. Passos, J.A., I.C.W., F.W., G.M., R.R., P.A., T.C., S.N., S.R., P.A., M.D.P., A.R., G.S., M.M.P., C.C., C.G., R.S., M. Borracino, C.B., R.M.D.M., C.A., A.D.D., G.D.L., M.G., P.B. declare no competing interests.","order":1,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Ethics"}}],"article-number":"581"}}