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M.A.A. reports consulting for GLG, Inc., unrelated to this work. E.S.L. has served on advisory boards or consulted for Bayer AG, SystoleHealth, Inc., Amissa Health and Roon, unrelated to this work. P.d.A. is a full-time employee of Google as of June 2022. K.K. is a full-time employee of DeepMind as of August 2022. M.H.P. has consulted for Vertex Pharmaceuticals, unrelated to this work. J.E.H. has previously received sponsored research support from Bayer AG. P.B. is an employee of Ember AI, has received sponsored research support from Bayer AG and IBM, and has consulted for Novartis and Prometheus Biosciences, unrelated to this work. S.A.L. is employed by Novartis as of July 2022; has received sponsored research support from Bristol Myers Squibb, Pfizer, Boehringer Ingelheim, Fitbit, Medtronic, Premier and IBM; and has consulted for Bristol Myers Squibb, Pfizer, Blackstone Life Sciences and Invitae, unrelated to this work. P.T.E. receives sponsored research support from Bayer AG, Bristol Myers Squibb, Pfizer and Novo Nordisk; he has also served on advisory boards or consulted for Bayer AG and is a member of the Board of Directors of Editas Medicine, Inc., unrelated to this work. The other authors declare no competing interests.","order":1,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Ethics"}}]}}