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C.J.K. reports equity from Alto Neuroscience. C.B.N. is supported by the National Institutes of Health, the National Institute of Mental Health, the Texas Child Mental Health Consortium and the National Institute of Alcohol Abuse and Alcoholism. C.B.N. is a consultant for ANeuroTech, Abbott Laboratories, Engrail Therapeutics, Clexio Biosciences Ltd., Sero (previously Galen Mental Health LLC), Goodcap Pharmaceuticals, Sage Therapeutics, Senseye Inc., Precisement Health, Autobahn Therapeutics Inc., EMA Wellness, Denovo Biopharma LLC, Alvogen, Acadia Pharmaceuticals, Inc., Reunion Neuroscience, Kivira Health, Inc., Wave Neuroscience, Patient Square Capital LP, Invisalert Solutions Inc. and Neurocrine Biosciences, LLC. C.B.N. owns the following patents: method and devices for transdermal delivery of lithium (US patent no. 6,375,990B1), method of assessing antidepressant drug therapy via transport inhibition of monoamine neurotransmitters by ex vivo assay (US patent no. 7,148,027B2) and compounds, compositions, methods of synthesis and methods of treatment (CRF receptor binding ligand) (US patent no. 8,551, 996 B2). C.B.N. owns stock in Corcept Therapeutics Company, EMA Wellness, Precisement Health, Relmada Therapeutics Inc., Signant Health, Galen Mental Health LLC, Kivira Health, Inc., Denovo Biopharma LLC and Senseye Inc. A.E. reports salary and equity from Alto Neuroscience and equity in Mindstrong Health. The other authors declare no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}