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This qualitative study explored mechanisms influencing healthcare transition and examined components of a novel intervention\u2014Transition Compass\u2014featuring automated messaging, access to a transition nurse coordinator, and educational modules. Data were collected via individual interviews (<jats:italic>n<\/jats:italic>\u2009=\u200915), AYA-parent dyadic interviews (<jats:italic>n<\/jats:italic>\u2009=\u20094), and focus groups (<jats:italic>n<\/jats:italic>\u2009=\u200915) with AYAs, parents\/carers, and healthcare professionals (<jats:italic>n<\/jats:italic>\u2009=\u200989) across five Australian states. Key factors affecting transition success included AYAs\u2019 evolving autonomy, variable expectations and knowledge across stakeholders, communication gaps, disconnects between healthcare systems, and inconsistencies in care. Participants viewed Transition Compass as a promising strategy to support AYAs through this critical phase.<\/jats:p>","DOI":"10.1038\/s44401-025-00041-4","type":"journal-article","created":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T09:14:55Z","timestamp":1759310095000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Co-design of an intervention to enhance healthcare transition for adolescents and young adults with chronic medical conditions"],"prefix":"10.1038","volume":"2","author":[{"given":"Ashlie","family":"Nobilo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jordana","family":"McLoone","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mary","family":"White","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hayley","family":"Smithers-Sheedy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jemma","family":"Anderson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raghu","family":"Lingam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cate","family":"Bailey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claire E.","family":"Wakefield","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jourdan Emily","family":"Hancock","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Hodgins","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"On behalf of the Transition Compass Investigator group","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosanna","family":"Cazzolli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evelyn","family":"Culnane","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angela","family":"Gialamas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nick","family":"Glasson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jane","family":"Ho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samantha","family":"Lain","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cecilia","family":"Moore","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kris","family":"Pierce","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katherine","family":"Steinbeck","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sue","family":"Woolfenden","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,10,1]]},"reference":[{"key":"41_CR1","unstructured":"Australian Bureau of Statistics (ABS). 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