{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T12:07:05Z","timestamp":1761394025061},"reference-count":33,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[1979,5,1]],"date-time":"1979-05-01T00:00:00Z","timestamp":294364800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Spinal Cord"],"published-print":{"date-parts":[[1979,5]]},"DOI":"10.1038\/sc.1979.12","type":"journal-article","created":{"date-parts":[[2011,4,7]],"date-time":"2011-04-07T23:18:35Z","timestamp":1302218315000},"page":"46-51","source":"Crossref","is-referenced-by-count":17,"title":["Cardiovascular aspects of autonomic dysreflexia since Guttmann and Whitteridge (1947)"],"prefix":"10.1038","volume":"17","author":[{"given":"H L","family":"Frankel","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C J","family":"Mathias","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"BFsc197912_CR1","first-page":"189","volume":"2","author":"JL Corbett","year":"1975","unstructured":"Corbett, J L, Debarge, O, Frankel, H L & Mathias, C J (1975). Cardiovascular responses in tetraplegic man to muscle spasm, bladder percussion and head-up tilt. Clinical and Experimental Pharmacology and Physiology, Supplement 2, 189\u2013193.","journal-title":"Clinical and Experimental Pharmacology and Physiology, Supplement"},{"key":"BFsc197912_CR2","doi-asserted-by":"publisher","first-page":"395","DOI":"10.1113\/jphysiol.1971.sp009476","volume":"215","author":"JL Corbett","year":"1971","unstructured":"Corbett, J L, Frankel, H L & Harris, P J (1971a). Cardiovascular reflex responses to cutaneous and visceral stimuli in spinal man. Journal of Physiology (London), 215, 395\u2013409.","journal-title":"Journal of Physiology (London)"},{"key":"BFsc197912_CR3","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1113\/jphysiol.1971.sp009475","volume":"215","author":"JL Corbett","year":"1971","unstructured":"Corbett, J L, Frankel, H L & Harris, P J (1971b). Cardiovascular changes associated with skeletal muscle spasm in tetraplegic man. Journal of Physiology (London), 215, 381\u2013393.","journal-title":"Journal of Physiology (London)"},{"key":"BFsc197912_CR4","first-page":"113","volume":"9","author":"JL Corbett","year":"1971","unstructured":"Corbett, J L, Frankel, H L & Harris, P J (1971c). Cardiovascular reflexes in tetraplegia. Paraplegia, 9, 113\u2013112.","journal-title":"Paraplegia"},{"key":"BFsc197912_CR5","doi-asserted-by":"publisher","first-page":"292","DOI":"10.1111\/j.1748-1716.1965.tb04276.x","volume":"65","author":"B Folkow","year":"1965","unstructured":"Folkow, B & Rubenstein, E H (1965). Behavioural and autonomic patterns evoked by stimulation of the lateral hypothalamic area in the cat. Acta Physiologica Scandinavica, 65, 292\u2013299.","journal-title":"Acta Physiologica Scandinavica"},{"key":"BFsc197912_CR6","first-page":"38","volume":"247","author":"HL Frankel","year":"1975","unstructured":"Frankel, H L, Mathias, C J, Smith, A D & Spalding, J M K (1975). Release of dopamine-beta-hydroxylase during sympathetic nervous activity in tetraplegic man. Journal of Physiology (London), 247, 38\u201340P.","journal-title":"Journal of Physiology (London)"},{"key":"BFsc197912_CR7","first-page":"205","volume":"12","author":"HL Frankel","year":"1974","unstructured":"Frankel, H L, Mathias, C J & Walsh, J J (1974). Blood pressure, plasma catecholamines and prostaglandins during artificial erection in a male tetraplegic. Paraplegia, 12, 205\u2013211.","journal-title":"Paraplegia"},{"key":"BFsc197912_CR8","doi-asserted-by":"publisher","first-page":"569","DOI":"10.1093\/cvr\/6.5.569","volume":"6","author":"FS Goldby","year":"1972","unstructured":"Goldby, F S & Beilin, L J (1972). How an acute rise in arterial pressure damages arterioles. Cardiovascular Research, 6, 569\u2013584.","journal-title":"Cardiovascular Research"},{"key":"BFsc197912_CR9","first-page":"161","volume":"8","author":"H Goller","year":"1970","unstructured":"Goller, H & Paeslack, V (1970). Our experiences about pregnancy and delivery of the paraplegic women. Paraplegia, 8, 161\u2013170.","journal-title":"Paraplegia"},{"key":"BFsc197912_CR10","first-page":"144","volume":"3","author":"L Guttmann","year":"1965","unstructured":"Guttmann, L, Frankel, H L & Paeslack, V (1965). Cardiac irregularities during labour in paraplegic women. Paraplegia, 3, 144\u2013151.","journal-title":"Paraplegia"},{"key":"BFsc197912_CR11","first-page":"383","volume":"56","author":"L Guttmann","year":"1963","unstructured":"Guttmann, L (1963). The paraplegic patient in pregnancy and labour. Proceedings of the Royal Society of Medicine, 56, 383\u2013387.","journal-title":"Proceedings of the Royal Society of Medicine"},{"key":"BFsc197912_CR12","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1038\/sc.1971.7","volume":"9","author":"L Guttmann","year":"1971","unstructured":"Guttmann, L & Walsh, J J (1971). Prostigmine assessment test of fertility in spinal man. Paraplegia, 9, 39\u201351.","journal-title":"Paraplegia"},{"key":"BFsc197912_CR13","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1093\/brain\/70.4.361","volume":"70","author":"L Guttmann","year":"1947","unstructured":"Guttmann, L & Whitteridge, D (1947). Effects of bladder distension on autonomic mechanisms after spinal cord injuries. Brain, 70, 361\u2013404.","journal-title":"Brain"},{"key":"BFsc197912_CR14","doi-asserted-by":"publisher","first-page":"188","DOI":"10.1093\/brain\/40.2-3.188","volume":"40","author":"H Head","year":"1917","unstructured":"Head, H & Riddoch, G (1917). The autonomic bladder, excessive sweating and some other reflex conditions, in gross injuries of the spinal cord. Brain, 40, 188\u2013263.","journal-title":"Brain"},{"key":"BFsc197912_CR15","unstructured":"Hilton, J (1860). A course of lectures in pain and the therapeutic influence of mechanical and physiological rest in accidents and surgical diseases. Lancet, October 27th., 401\u2013404."},{"key":"BFsc197912_CR16","first-page":"1105","volume":"84","author":"H Jung","year":"1962","unstructured":"Jung, H & Schmidt, K (1962). Zur Geburt nach Querschnittsl\u00e4hmung. Zbl. Gyn\u00e4k., 84, 1105\u20131111.","journal-title":"Zbl. Gyn\u00e4k."},{"key":"BFsc197912_CR17","doi-asserted-by":"publisher","first-page":"395","DOI":"10.1016\/0024-3205(75)90260-X","volume":"16","author":"DA Kristt","year":"1975","unstructured":"Kristt, D A (1975). Diencephalic vasodepressor responses independent of heart rate changes. Life Sciences, 16, 395\u2013402.","journal-title":"Life Sciences"},{"key":"BFsc197912_CR18","doi-asserted-by":"publisher","first-page":"204","DOI":"10.1161\/01.RES.39.2.204","volume":"39","author":"CJ Mathias","year":"1976","unstructured":"Mathias, C J, Christensen, N J, Corbett, J L, Frankel, H L & Spalding, J M K (1976a). Plasma catecholamines during paroxysmal neurogenic hypertension in quadriplegic man. Circulation Research, 39, 204\u2013208.","journal-title":"Circulation Research"},{"key":"BFsc197912_CR19","first-page":"168","volume":"3","author":"CJ Mathias","year":"1977","unstructured":"Mathias, C J, Christensen, N J, Frankel, H L & Spalding, J M K (1977). Neurocirculatory dysfunction in patients soon after cervical spinal cord transection. European Journal of Intensive Care Medicine, 3, 168.","journal-title":"European Journal of Intensive Care Medicine"},{"key":"BFsc197912_CR20","unstructured":"Mathias, C J, Christensen, N J, Frankel, H L & Spalding, J M K (1979a). Cardiovascular control in recently injured tetraplegics in spinal shock. Quarterly Journal of Medicine, in press."},{"key":"BFsc197912_CR21","doi-asserted-by":"publisher","first-page":"757","DOI":"10.1093\/brain\/99.4.757","volume":"99","author":"CJ Mathias","year":"1976","unstructured":"Mathias, C J, Frankel, H L, Christensen, N J & Spalding, J M K (1976b). Enhanced pressor response to noradrenaline in patients with cervical spinal cord transection. Brain, 99, 757\u2013770.","journal-title":"Brain"},{"key":"BFsc197912_CR22","unstructured":"Mathias, C J, Frankel, H L & Peart, W S (1979b). Unpublished observations."},{"key":"BFsc197912_CR23","unstructured":"Mathias, C J, Frankel, H L, Wing, L M H & Reid, J L (1979c). Unpublished observations."},{"key":"BFsc197912_CR24","first-page":"625","volume":"49","author":"CJ Mathias","year":"1975","unstructured":"Mathias, C J, Hillier, K, Frankel, H L & Spalding, J M K (1975). Plasma prostaglandin E during neurogenic hypertension in tetraplegic man. Clinical Science and Molecular Medicine, 49, 625\u2013628.","journal-title":"Clinical Science and Molecular Medicine"},{"key":"BFsc197912_CR25","doi-asserted-by":"publisher","first-page":"176","DOI":"10.1093\/cvr\/10.2.176","volume":"10","author":"CJ Mathias","year":"1976","unstructured":"Mathias, C J, Smith, A D, Frankel, H L & Spalding, J M K (1976c). Release of dopamine-beta-hydroxylase during hypertension from sympathetic overactivity in man. Cardiovascular Research, 10, 176\u2013181.","journal-title":"Cardiovascular Research"},{"key":"BFsc197912_CR26","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1152\/jn.1951.14.2.85","volume":"14","author":"LJ Pollock","year":"1951","unstructured":"Pollock, L J, Boshes, B, Chor, H, Finkelman, I, Arieff, A J & Brown, M (1951). Defects in regulatory mechanisms of autonomic function in injuries to spinal cord. Journal of Neurophysiology, 14, 85\u201393.","journal-title":"Journal of Neurophysiology"},{"key":"BFsc197912_CR27","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1002\/cpt1977214375","volume":"21","author":"JL Reid","year":"1977","unstructured":"Reid, J L, Wing, L M H, Mathias, C J, Frankel, H L & Neill, E (1977). The central hypotensive effect of clonidine: Studies in tetraplegic subjects. Clinical Pharmacology and Therapeutics, 21, 375\u2013381.","journal-title":"Clinical Pharmacology and Therapeutics"},{"issue":"Suppl. 2","key":"BFsc197912_CR28","first-page":"179","volume":"2","author":"DJ Reis","year":"1975","unstructured":"Reis, D J, Nathan, M A & Doba, N (1975). Two specific brainstem systems which regulate the blood pressure. Clinical and Experimental Pharmacology and Physiology, 2, Suppl. 2, 179\u2013183.","journal-title":"Clinical and Experimental Pharmacology and Physiology"},{"key":"BFsc197912_CR29","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1093\/brain\/40.2-3.264","volume":"40","author":"G Riddoch","year":"1917","unstructured":"Riddoch, G (1917). The reflex functions of the completely divided spinal cord in man compared with those associated with less severe lesions. Brain, 40, 264\u2013402.","journal-title":"Brain"},{"key":"BFsc197912_CR30","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1038\/sc.1971.8","volume":"9","author":"AB Rossier","year":"1971","unstructured":"Rossier, A B, Ziegler, W H, Duchosal, P W & Meylan, J (1971). Sexual function and dysreflexia. Paraplegia, 9, 51\u201359.","journal-title":"Paraplegia"},{"key":"BFsc197912_CR31","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1056\/NEJM194808192390803","volume":"239","author":"CE Thompson","year":"1948","unstructured":"Thompson, C E & Witham, A C (1948). Paroxysmal hypertension in spinal cord injuries. New England Medical Journal, 239, 291\u2013294.","journal-title":"New England Medical Journal"},{"key":"BFsc197912_CR32","first-page":"15","volume":"6","author":"SE Von-Euler","year":"1954","unstructured":"Von-Euler, S E (1954). Adrenaline and nor-adrenaline: distribution and action. Physiological Reviews, 6, 15\u201322.","journal-title":"Physiological Reviews"},{"key":"BFsc197912_CR33","doi-asserted-by":"publisher","first-page":"1349","DOI":"10.1126\/science.174.4016.1349","volume":"174","author":"RM Weinshilboum","year":"1971","unstructured":"Weinshilboum, R M, Kvetnansky, R, Axelrod, J & Kopin, I J (1971). Proportional release of nor-epinephrine and dopamine-beta-hydroxylase from sympathetic nerves. Science, 174, 1349\u20131351.","journal-title":"Science"}],"container-title":["Spinal Cord"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/sc197912.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/sc197912","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/sc197912.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,20]],"date-time":"2023-05-20T22:00:22Z","timestamp":1684620022000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/sc197912"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1979,5]]},"references-count":33,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1979,5]]}},"alternative-id":["BFsc197912"],"URL":"https:\/\/doi.org\/10.1038\/sc.1979.12","relation":{},"ISSN":["1362-4393","1476-5624"],"issn-type":[{"value":"1362-4393","type":"print"},{"value":"1476-5624","type":"electronic"}],"subject":[],"published":{"date-parts":[[1979,5]]}}}