{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T08:30:35Z","timestamp":1769157035218,"version":"3.49.0"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2011,7,26]],"date-time":"2011-07-26T00:00:00Z","timestamp":1311638400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Spinal Cord"],"published-print":{"date-parts":[[2011,12]]},"DOI":"10.1038\/sc.2011.74","type":"journal-article","created":{"date-parts":[[2011,7,26]],"date-time":"2011-07-26T09:25:05Z","timestamp":1311672305000},"page":"1182-1187","source":"Crossref","is-referenced-by-count":28,"title":["Plasma IL-6 levels during arm exercise in persons with spinal cord injury"],"prefix":"10.1038","volume":"49","author":[{"given":"Y","family":"Umemoto","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K","family":"Furusawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K","family":"Kouda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y","family":"Sasaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N","family":"Kanno","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D","family":"Kojima","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F","family":"Tajima","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2011,7,26]]},"reference":[{"key":"BFsc201174_CR1","doi-asserted-by":"publisher","first-page":"1379","DOI":"10.1152\/physrev.90100.2007","volume":"88","author":"BK Pedersen","year":"2008","unstructured":"Pedersen BK, Febbraio MA . Muscle as an endocrine organ: focus on muscle-derived interleukin-6. Physiol Rev 2008; 88: 1379\u20131406.","journal-title":"Physiol Rev"},{"key":"BFsc201174_CR2","doi-asserted-by":"publisher","first-page":"919","DOI":"10.1016\/S0929-6646(08)60062-5","volume":"106","author":"TD Wang","year":"2007","unstructured":"Wang TD, Wang YH, Huang TS, Su TC, Pan SL, Chen SY . Circulating levels of markers of inflammation and endothelial activation are increased in men with chronic spinal cord injury. J Formos Med Assoc 2007; 106: 919\u2013928.","journal-title":"J Formos Med Assoc"},{"key":"BFsc201174_CR3","doi-asserted-by":"publisher","first-page":"466","DOI":"10.1038\/sj.sc.3102161","volume":"46","author":"WA Bauman","year":"2008","unstructured":"Bauman WA, Spungen AM . Coronary heart disease in individuals with spinal cord injury: assessment of risk factors. Spinal Cord 2008; 46: 466\u2013476.","journal-title":"Spinal Cord"},{"key":"BFsc201174_CR4","doi-asserted-by":"publisher","first-page":"345","DOI":"10.1111\/j.1365-201X.2005.01407.x","volume":"183","author":"M Bergfors","year":"2005","unstructured":"Bergfors M, Barnekow-Bergkvist M, Kalezic N, Lyskov E, Eriksson JW . Short-term effects of repetitive arm work and dynamic exercise on glucose metabolism and insulin sensitivity. Acta Physiol Scand 2005; 183: 345\u2013356.","journal-title":"Acta Physiol Scand"},{"key":"BFsc201174_CR5","doi-asserted-by":"publisher","first-page":"633","DOI":"10.1113\/jphysiol.2004.066779","volume":"558","author":"CP Fischer","year":"2004","unstructured":"Fischer CP, Hiscock N, Basu S, Vessby B, Kallner A, Pedersen BK et al. Supplementation with vitamins C and E inhibits the release of interleukin-6 from contracting human skeletal muscle. J Physiol 2004; 558: 633\u2013645.","journal-title":"J Physiol"},{"key":"BFsc201174_CR6","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1111\/j.1469-7793.2000.00237.x","volume":"529","author":"A Steensberg","year":"2000","unstructured":"Steensberg A, van Hall G, Osada T, Sacchetti M, Saltin B, Klarlund PB . Production of interleukin-6 in contracting human skeletal muscles can account for the exercise-induced increase in plasma interleukin-6. J Physiol 2000; 529: 237\u2013242.","journal-title":"J Physiol"},{"key":"BFsc201174_CR7","first-page":"6","volume":"12","author":"CP Fischer","year":"2006","unstructured":"Fischer CP . Interleukin-6 in acute exercise and training: what is the biological relevance? Exerc Immunol Rev 2006; 12: 6\u201333.","journal-title":"Exerc Immunol Rev"},{"key":"BFsc201174_CR8","doi-asserted-by":"publisher","first-page":"512","DOI":"10.1007\/s004210000312","volume":"83","author":"K Ostrowski","year":"2000","unstructured":"Ostrowski K, Schjerling P, Pedersen BK . Physical activity and plasma interleukin-6 in humans: effect of intensity of exercise. Eur J Appl Physiol 2000; 83: 512\u2013515.","journal-title":"Eur J Appl Physiol"},{"key":"BFsc201174_CR9","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1038\/sj.sc.3102054","volume":"46","author":"M Ueta","year":"2008","unstructured":"Ueta M, Furusawa K, Takahashi M, Akatsu Y, Nakamura T, Tajima F . Attenuation of natural killer cell activity during 2-h exercise in individuals with spinal cord injuries. Spinal Cord 2008; 46: 26\u201332.","journal-title":"Spinal Cord"},{"key":"BFsc201174_CR10","doi-asserted-by":"publisher","first-page":"340","DOI":"10.1016\/0003-2697(88)90198-4","volume":"173","author":"LW Hunter","year":"1998","unstructured":"Hunter LW, Rorie DK, Yaksh TL, Tyce GM . Concurrent separation of catecholamines, dihydroxyphenylglycol, vasoactive intestinal peptide, and neuropeptide Y in superfusate and tissue extract. Anal Biochem 1998; 173: 340\u2013352.","journal-title":"Anal Biochem"},{"key":"BFsc201174_CR11","doi-asserted-by":"publisher","first-page":"833","DOI":"10.1113\/jphysiol.1997.sp021972","volume":"499","author":"H Bruunsgaard","year":"1997","unstructured":"Bruunsgaard H, Galbo H, Halkjaer-Kristensen J, Johansen TL, MacLean DA, Pedersen BK . Exercise-induced increase in serum interleukin-6 in humans is related to muscle damage. J Physiol 1997; 499: 833\u2013841.","journal-title":"J Physiol"},{"key":"BFsc201174_CR12","doi-asserted-by":"publisher","first-page":"1662","DOI":"10.1152\/jappl.1997.82.5.1662","volume":"82","author":"SL Nehlsen-Canarella","year":"1997","unstructured":"Nehlsen-Canarella SL, Fagoaga OR, Nieman DC, Henson DA, Butterworth DE, Davis JM et al. Carbohydrate and the cytokine response to 2.5\u2009h of running. J Appl Physiol 1997; 82: 1662\u20131667.","journal-title":"J Appl Physiol"},{"key":"BFsc201174_CR13","doi-asserted-by":"publisher","first-page":"2748","DOI":"10.1096\/fj.01-0507fje","volume":"15","author":"C Keller","year":"2001","unstructured":"Keller C, Steensberg A, Pilegaard H, Osada T, Saltin B, Pedersen BK et al. Transcriptional activation of the IL-6 gene in human contracting skeletal muscle: influence of muscle glycogen content. FASEB J 2001; 15: 2748\u20132750.","journal-title":"FASEB J"},{"key":"BFsc201174_CR14","doi-asserted-by":"publisher","first-page":"E397","DOI":"10.1152\/ajpendo.00134.2003","volume":"285","author":"MA Febbraio","year":"2003","unstructured":"Febbraio MA, Ott P, Nielsen HB, Steensberg A, Keller C, Pedersen BK et al. Hepatosplanchnic clearance of interleukin-6 in humans during exercise. Am J Physiol Endocrinol Metab 2003; 285: E397\u2013E402.","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"BFsc201174_CR15","doi-asserted-by":"publisher","first-page":"927","DOI":"10.1113\/jphysiol.2003.044883","volume":"550","author":"C Keller","year":"2003","unstructured":"Keller C, Keller P, Marshall-Gradisnik SM, Pedersen BK . IL-6gene expression in human adipose tissue in response to exercise: effect of carbohydrate ingestion. J Physiol 2003; 550: 927\u2013931.","journal-title":"J Physiol"},{"key":"BFsc201174_CR16","first-page":"R191","volume":"271","author":"M Kjaer","year":"1996","unstructured":"Kjaer M, Pollack SF, Mohr T, Weiss H, Gleim GW, Ragnarsson KT et al. Regulation of glucose turnover and hormonal responses during electrical cycling in tetraplegic humans. Am J Physiol 1996; 271: R191\u2013R199.","journal-title":"Am J Physiol"},{"key":"BFsc201174_CR17","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1097\/00003677-200507000-00003","volume":"33","author":"MA Febbraio","year":"2005","unstructured":"Febbraio MA, Pedersen BK . Contraction-induced myokine production and release: is skeletal muscle an endocrine organ? Exerc Sport Sci Rev 2005; 33: 114\u2013119.","journal-title":"Exerc Sport Sci Rev"},{"key":"BFsc201174_CR18","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1055\/s-2007-1021034","volume":"15","author":"H Kuipers","year":"1994","unstructured":"Kuipers H . Exercise-induced muscle damage. Int J Sports Med 1994; 15: 132\u2013135.","journal-title":"Int J Sports Med"},{"key":"BFsc201174_CR19","doi-asserted-by":"publisher","first-page":"889","DOI":"10.1111\/j.1469-7793.1998.889ba.x","volume":"513","author":"K Ostowski","year":"1998","unstructured":"Ostowski K, Hermann C, Bangash A, Schjerling P, Nielsen JN, Pedersen BK . A trauma-like elevation of plasma cytokines in humans in response to treadmill running. J Physiol 1998; 513: 889\u2013894.","journal-title":"J Physiol"},{"key":"BFsc201174_CR20","doi-asserted-by":"publisher","first-page":"992","DOI":"10.1096\/fj.03-1259fje","volume":"18","author":"N Hiscock","year":"2004","unstructured":"Hiscock N, Chan MH, Bisucci T, Darby IA, Febbraio MA . Skeletal myocytes are a source of interleukin-6 mRNA expression and protein release during contraction: evidence of fiber type specificity. FASEB J 2004; 18: 992\u2013994.","journal-title":"FASEB J"}],"container-title":["Spinal Cord"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/sc201174.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/sc201174","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/sc201174.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,20]],"date-time":"2023-05-20T22:22:09Z","timestamp":1684621329000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/sc201174"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,7,26]]},"references-count":20,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2011,12]]}},"alternative-id":["BFsc201174"],"URL":"https:\/\/doi.org\/10.1038\/sc.2011.74","relation":{},"ISSN":["1362-4393","1476-5624"],"issn-type":[{"value":"1362-4393","type":"print"},{"value":"1476-5624","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,7,26]]}}}