{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T08:47:03Z","timestamp":1791362823299,"version":"4.3.1"},"reference-count":64,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2017,1,24]],"date-time":"2017-01-24T00:00:00Z","timestamp":1485216000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Spinal Cord"],"published-print":{"date-parts":[[2017,6]]},"DOI":"10.1038\/sc.2016.191","type":"journal-article","created":{"date-parts":[[2017,1,24]],"date-time":"2017-01-24T10:30:49Z","timestamp":1485253849000},"page":"575-582","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Usefulness of laser-evoked potentials and quantitative sensory testing in the diagnosis of neuropathic spinal cord injury pain: a multiple case study"],"prefix":"10.1038","volume":"55","author":[{"given":"G","family":"Landmann","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M F","family":"Berger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L","family":"Stockinger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E","family":"Opsommer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,1,24]]},"reference":[{"key":"BFsc2016191_CR1","doi-asserted-by":"publisher","first-page":"352","DOI":"10.1038\/sc.2008.136","volume":"47","author":"PJ Siddall","year":"2009","unstructured":"Siddall PJ . Management of neuropathic pain following spinal cord injury: now and in the future. Spinal Cord 2009; 47: 352\u2013359.","journal-title":"Spinal Cord"},{"key":"BFsc2016191_CR2","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1016\/S0304-3959(02)00452-9","volume":"103","author":"PJ Siddall","year":"2003","unstructured":"Siddall PJ, McClelland JM, Rutkowski SB, Cousins MJ . A longitudinal study of the prevalence and characteristics of pain in the first 5 years following spinal cord injury. Pain 2003; 103: 249\u2013257.","journal-title":"Pain"},{"key":"BFsc2016191_CR3","doi-asserted-by":"publisher","first-page":"809","DOI":"10.1038\/sc.2015.219","volume":"54","author":"S Mahnig","year":"2016","unstructured":"Mahnig S, Landmann G, Stockinger L, Opsommer E . Pain assessment according to the International Spinal Cord Injury Pain classification in patients with spinal cord injury referred to a multidisciplinary pain center. Spinal Cord 2016; 54: 809\u2013815.","journal-title":"Spinal Cord"},{"key":"BFsc2016191_CR4","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1016\/j.pain.2010.06.019","volume":"150","author":"NB Finnerup","year":"2010","unstructured":"Finnerup NB, Sindrup SH, Jensen TS . The evidence for pharmacological treatment of neuropathic pain. Pain 2010; 150: 573\u2013581.","journal-title":"Pain"},{"key":"BFsc2016191_CR5","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1038\/sc.2011.156","volume":"50","author":"TN Bryce","year":"2012","unstructured":"Bryce TN, Biering-Sorensen F, Finnerup NB, Cardenas DD, Defrin R, Lundeberg T et al. International spinal cord injury pain classification: part I. Background and description Spinal Cord 2012; 50: 413\u2013417.","journal-title":"Spinal Cord"},{"key":"BFsc2016191_CR6","doi-asserted-by":"publisher","first-page":"1630","DOI":"10.1212\/01.wnl.0000282763.29778.59","volume":"70","author":"RD Treede","year":"2008","unstructured":"Treede RD, Jensen TS, Campbell JN, Cruccu G, Dostrovsky JO, Griffin JW et al. Neuropathic pain: redefinition and a grading system for clinical and research purposes. Neurology 2008; 70: 1630\u20131635.","journal-title":"Neurology"},{"key":"BFsc2016191_CR7","doi-asserted-by":"publisher","first-page":"1599","DOI":"10.1097\/j.pain.0000000000000492","volume":"157","author":"NB Finnerup","year":"2016","unstructured":"Finnerup NB, Haroutounian S, Kamerman P, Baron R, Bennett DL, Bouhassira D et al. Neuropathic pain: an updated grading system for research and clinical practice. Pain 2016; 157: 1599\u20131606.","journal-title":"Pain"},{"key":"BFsc2016191_CR8","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1007\/s11916-012-0259-x","volume":"16","author":"NB Finnerup","year":"2012","unstructured":"Finnerup NB, Baastrup C . Spinal cord injury pain: mechanisms and management. Curr Pain Headache Rep 2012; 16: 207\u2013216.","journal-title":"Curr Pain Headache Rep"},{"key":"BFsc2016191_CR9","doi-asserted-by":"publisher","first-page":"569","DOI":"10.1111\/1754-9485.12202","volume":"58","author":"J Watts","year":"2014","unstructured":"Watts J, Box GA, Galvin A, Van Tonder F, Trost N, Sutherland T . Magnetic resonance imaging of intramedullary spinal cord lesions: a pictorial review. J Med Imag Radiat Oncol 2014; 58: 569\u2013581.","journal-title":"J Med Imag Radiat Oncol"},{"key":"BFsc2016191_CR10","doi-asserted-by":"publisher","first-page":"461","DOI":"10.12659\/PJR.890944","volume":"79","author":"D Szwedowski","year":"2014","unstructured":"Szwedowski D, Walecki J . Spinal Cord Injury without Radiographic Abnormality (SCIWORA)\u2014clinical and radiological aspects. Pol J Radiol 2014; 79: 461\u2013464.","journal-title":"Pol J Radiol"},{"key":"BFsc2016191_CR11","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1016\/j.clineuro.2008.02.004","volume":"110","author":"K Yucesoy","year":"2008","unstructured":"Yucesoy K, Yuksel KZ . SCIWORA in MRI era. Clin Neurol Neurosurg 2008; 110: 429\u2013433.","journal-title":"Clin Neurol Neurosurg"},{"key":"BFsc2016191_CR12","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1016\/B978-0-444-52137-8.00004-8","volume":"109","author":"A Curt","year":"2012","unstructured":"Curt A, Ellaway PH . Clinical neurophysiology in the prognosis and monitoring of traumatic spinal cord injury. Handb Clin Neurol 2012; 109: 63\u201375.","journal-title":"Handb Clin Neurol"},{"key":"BFsc2016191_CR13","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1007\/s00441-012-1373-0","volume":"349","author":"J Haefeli","year":"2012","unstructured":"Haefeli J, Curt A . Refined sensory measures of neural repair in human spinal cord injury: bridging preclinical findings to clinical value. Cell Tissue Res 2012; 349: 397\u2013404.","journal-title":"Cell Tissue Res"},{"key":"BFsc2016191_CR14","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1016\/j.pain.2010.07.031","volume":"152","author":"M Haanpaa","year":"2011","unstructured":"Haanpaa M, Attal N, Backonja M, Baron R, Bennett M, Bouhassira D et al. NeuPSIG guidelines on neuropathic pain assessment. Pain 2011; 152: 14\u201327.","journal-title":"Pain"},{"key":"BFsc2016191_CR15","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1016\/j.neucli.2003.10.009","volume":"33","author":"RD Treede","year":"2003","unstructured":"Treede RD, Lorenz J, Baumgartner U . Clinical usefulness of laser-evoked potentials. Clin Neurophysiol 2003; 33: 303\u2013314.","journal-title":"Clin Neurophysiol"},{"key":"BFsc2016191_CR16","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1007\/s10072-011-0476-9","volume":"32","author":"C Geber","year":"2011","unstructured":"Geber C, Baumgartner U, Fechir M, Vogt T, Birklein F, Treede RD . Comparison of LEP and QST and their contribution to standard sensory diagnostic assessment of spinal lesions: a pilot study. Neurol Sci 2011; 32: 401\u2013410.","journal-title":"Neurol Sci"},{"key":"BFsc2016191_CR17","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1016\/j.pain.2006.01.041","volume":"123","author":"R Rolke","year":"2006","unstructured":"Rolke R, Baron R, Maier C, Tolle TR, Treede RD, Beyer A et al. Quantitative sensory testing in the German Research Network on Neuropathic Pain (DFNS): standardized protocol and reference values. Pain 2006; 123: 231\u2013243.","journal-title":"Pain"},{"key":"BFsc2016191_CR18","doi-asserted-by":"publisher","first-page":"598","DOI":"10.1016\/j.pain.2010.07.026","volume":"151","author":"W Magerl","year":"2010","unstructured":"Magerl W, Krumova EK, Baron R, Tolle T, Treede RD, Maier C . Reference data for quantitative sensory testing (QST): refined stratification for age and a novel method for statistical comparison of group data. Pain 2010; 151: 598\u2013605.","journal-title":"Pain"},{"key":"BFsc2016191_CR19","doi-asserted-by":"publisher","first-page":"1002","DOI":"10.1016\/j.pain.2014.02.004","volume":"155","author":"DB Pfau","year":"2014","unstructured":"Pfau DB, Krumova EK, Treede RD, Baron R, Toelle T, Birklein F et al. Quantitative sensory testing in the German Research Network on Neuropathic Pain (DFNS): reference data for the trunk and application in patients with chronic postherpetic neuralgia. Pain 2014; 155: 1002\u20131015.","journal-title":"Pain"},{"key":"BFsc2016191_CR20","doi-asserted-by":"publisher","first-page":"1807","DOI":"10.1016\/j.pain.2013.05.047","volume":"154","author":"MM Backonja","year":"2013","unstructured":"Backonja MM, Attal N, Baron R, Bouhassira D, Drangholt M, Dyck PJ et al. Value of quantitative sensory testing in neurological and pain disorders: NeuPSIG consensus. Pain 2013; 154: 1807\u20131819.","journal-title":"Pain"},{"key":"BFsc2016191_CR21","doi-asserted-by":"publisher","first-page":"2234","DOI":"10.1097\/j.pain.0000000000000266","volume":"156","author":"DT Demant","year":"2015","unstructured":"Demant DT, Lund K, Finnerup NB, Vollert J, Maier C, Segerdahl MS et al. Pain relief with lidocaine 5% patch in localized peripheral neuropathic pain in relation to pain phenotype: a randomised, double-blind, and placebo-controlled, phenotype panel study. Pain 2015; 156: 2234\u20132244.","journal-title":"Pain"},{"key":"BFsc2016191_CR22","doi-asserted-by":"publisher","first-page":"2263","DOI":"10.1016\/j.pain.2014.08.014","volume":"155","author":"DT Demant","year":"2014","unstructured":"Demant DT, Lund K, Vollert J, Maier C, Segerdahl M, Finnerup NB et al. The effect of oxcarbazepine in peripheral neuropathic pain depends on pain phenotype: a randomised, double-blind, placebo-controlled phenotype-stratified study. Pain 2014; 155: 2263\u20132273.","journal-title":"Pain"},{"issue":"Part 1","key":"BFsc2016191_CR23","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1093\/brain\/awg007","volume":"126","author":"NB Finnerup","year":"2003","unstructured":"Finnerup NB, Johannesen IL, Fuglsang-Frederiksen A, Bach FW, Jensen TS . Sensory function in spinal cord injury patients with and without central pain. Brain 2003; 126 (Part 1): 57\u201370.","journal-title":"Brain"},{"key":"BFsc2016191_CR24","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1016\/j.expneurol.2007.06.001","volume":"207","author":"NB Finnerup","year":"2007","unstructured":"Finnerup NB, Sorensen L, Biering-Sorensen F, Johannesen IL, Jensen TS . Segmental hypersensitivity and spinothalamic function in spinal cord injury pain. Exp Neurol 2007; 207: 139\u2013149.","journal-title":"Exp Neurol"},{"key":"BFsc2016191_CR25","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1016\/j.jpain.2013.09.008","volume":"15","author":"NB Finnerup","year":"2014","unstructured":"Finnerup NB, Norrbrink C, Trok K, Piehl F, Johannesen IL, Sorensen JC et al. Phenotypes and predictors of pain following traumatic spinal cord injury: a prospective study. J Pain 2014; 15: 40\u201348.","journal-title":"J Pain"},{"issue":"Part 2","key":"BFsc2016191_CR26","doi-asserted-by":"publisher","first-page":"418","DOI":"10.1093\/brain\/awr270","volume":"135","author":"G Zeilig","year":"2012","unstructured":"Zeilig G, Enosh S, Rubin-Asher D, Lehr B, Defrin R . The nature and course of sensory changes following spinal cord injury: predictive properties and implications on the mechanism of central pain. Brain 2012; 135 (Part 2): 418\u2013430.","journal-title":"Brain"},{"key":"BFsc2016191_CR27","doi-asserted-by":"publisher","first-page":"1537","DOI":"10.1016\/j.pain.2012.02.031","volume":"153","author":"A Westermann","year":"2012","unstructured":"Westermann A, Krumova EK, Pennekamp W, Horch C, Baron R, Maier C . Different underlying pain mechanisms despite identical pain characteristics: a case report of a patient with spinal cord injury. Pain 2012; 153: 1537\u20131540.","journal-title":"Pain"},{"key":"BFsc2016191_CR28","unstructured":"The Federal Authorities of the Swiss Confederation. Human Research Ordinance. Available at:\n                    https:\/\/www.admin.ch\/opc\/en\/classified-compilation\/20061313\/index.html\n                    \n                  ."},{"key":"BFsc2016191_CR29","doi-asserted-by":"publisher","first-page":"535","DOI":"10.1179\/204577211X13207446293695","volume":"34","author":"SC Kirshblum","year":"2011","unstructured":"Kirshblum SC, Burns SP, Biering-Sorensen F, Donovan W, Graves DE, Jha A et al. International standards for neurological classification of spinal cord injury (revised 2011). J Spinal Cord Med 2011; 34: 535\u2013546.","journal-title":"J Spinal Cord Med"},{"key":"BFsc2016191_CR30","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1007\/s00482-002-0162-1","volume":"16","author":"B Nagel","year":"2002","unstructured":"Nagel B, Gerbershagen HU, Lindena G, Pfingsten M . Development and evaluation of the multidimensional German pain questionnaire]. Schmerz (Berlin, Germany) 2002; 16: 263\u2013270.","journal-title":"Schmerz (Berlin, Germany)"},{"key":"BFsc2016191_CR31","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1097\/00005650-199603000-00003","volume":"34","author":"J Ware Jr","year":"1996","unstructured":"Ware J Jr, Kosinski M, Keller SD . A 12-Item Short-Form Health Survey: construction of scales and preliminary tests of reliability and validity. Med care 1996; 34: 220\u2013233.","journal-title":"Med care"},{"key":"BFsc2016191_CR32","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1055\/s-0030-1267085","volume":"2","author":"JR Wilson","year":"2011","unstructured":"Wilson JR, Hashimoto RE, Dettori JR, Fehlings MG . Spinal cord injury and quality of life: a systematic review of outcome measures. Evidence-Based Spine-Care J 2011; 2: 37\u201344.","journal-title":"Evidence-Based Spine-Care J"},{"key":"BFsc2016191_CR33","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1016\/0304-3959(92)90154-4","volume":"50","author":"M Von Korff","year":"1992","unstructured":"Von Korff M, Ormel J, Keefe FJ, Dworkin SF . Grading the severity of chronic pain. Pain 1992; 50: 133\u2013149.","journal-title":"Pain"},{"key":"BFsc2016191_CR34","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1016\/j.jpain.2005.10.007","volume":"7","author":"KA Raichle","year":"2006","unstructured":"Raichle KA, Osborne TL, Jensen MP, Cardenas D . The reliability and validity of pain interference measures in persons with spinal cord injury. J Pain 2006; 7: 179\u2013186.","journal-title":"J Pain"},{"key":"BFsc2016191_CR35","first-page":"459","volume":"27","author":"U Gerbershagen","year":"1986","unstructured":"Gerbershagen U . Organized treatment of pain. Determination of status. Der Internist 1986; 27: 459\u2013469.","journal-title":"Der Internist"},{"key":"BFsc2016191_CR36","doi-asserted-by":"publisher","first-page":"725","DOI":"10.1016\/S1388-2457(99)00297-7","volume":"111","author":"J Spiegel","year":"2000","unstructured":"Spiegel J, Hansen C, Treede RD . Clinical evaluation criteria for the assessment of impaired pain sensitivity by thulium-laser evoked potentials. Clin Neurophysiol 2000; 111: 725\u2013735.","journal-title":"Clin Neurophysiol"},{"key":"BFsc2016191_CR37","doi-asserted-by":"publisher","first-page":"439","DOI":"10.1016\/j.pain.2010.05.002","volume":"150","author":"C Maier","year":"2010","unstructured":"Maier C, Baron R, Tolle TR, Binder A, Birbaumer N, Birklein F et al. Quantitative sensory testing in the German Research Network on Neuropathic Pain (DFNS): somatosensory abnormalities in 1236 patients with different neuropathic pain syndromes. Pain 2010; 150: 439\u2013450.","journal-title":"Pain"},{"key":"BFsc2016191_CR38","doi-asserted-by":"publisher","first-page":"1010","DOI":"10.1111\/j.1468-1331.2010.02969.x","volume":"17","author":"G Cruccu","year":"2010","unstructured":"Cruccu G, Sommer C, Anand P, Attal N, Baron R, Garcia-Larrea L et al. EFNS guidelines on neuropathic pain assessment: revised 2009. Eur J Neurol 2010; 17: 1010\u20131018.","journal-title":"Eur J Neurol"},{"key":"BFsc2016191_CR39","doi-asserted-by":"publisher","first-page":"240","DOI":"10.1007\/s00482-003-0227-9","volume":"17","author":"J Frettloh","year":"2003","unstructured":"Frettloh J, Maier C, Gockel H, Huppe M . Validation of the German Mainz Pain Staging System in different pain syndromes. Schmerz (Berlin, Germany) 2003; 17: 240\u2013251.","journal-title":"Schmerz (Berlin, Germany)"},{"key":"BFsc2016191_CR40","first-page":"518716","volume":"2014","author":"J de Andres","year":"2014","unstructured":"de Andres J, de la Calle JL, Perez M, Lopez V . Clinical characteristics, patient-reported outcomes, and previous therapeutic management of patients with uncontrolled neuropathic pain referred to pain clinics. Pain Res Treat 2014; 2014: 518716.","journal-title":"Pain Res Treat"},{"key":"BFsc2016191_CR41","doi-asserted-by":"publisher","first-page":"e90130","DOI":"10.1371\/journal.pone.0090130","volume":"9","author":"C Fekete","year":"2014","unstructured":"Fekete C, Siegrist J, Reinhardt JD, Brinkhof MW . Is financial hardship associated with reduced health in disability? The case of spinal cord injury in Switzerland. PLoS ONE 2014; 9: e90130.","journal-title":"PLoS ONE"},{"key":"BFsc2016191_CR42","doi-asserted-by":"publisher","first-page":"792","DOI":"10.1136\/jnnp.71.6.792","volume":"71","author":"GD Iannetti","year":"2001","unstructured":"Iannetti GD, Truini A, Galeotti F, Romaniello A, Manfredi M, Cruccu G . Usefulness of dorsal laser evoked potentials in patients with spinal cord damage: report of two cases. J Neurol Neurosurg Psychiatry 2001; 71: 792\u2013794.","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"Part 4","key":"BFsc2016191_CR43","doi-asserted-by":"publisher","first-page":"1871","DOI":"10.1093\/brain\/114.4.1871","volume":"114","author":"R Kakigi","year":"1991","unstructured":"Kakigi R, Shibasaki H, Kuroda Y, Neshige R, Endo C, Tabuchi K et al. Pain-related somatosensory evoked potentials in syringomyelia. Brain 1991; 114 (Part 4): 1871\u20131889.","journal-title":"Brain"},{"issue":"Part 4","key":"BFsc2016191_CR44","doi-asserted-by":"publisher","first-page":"1595","DOI":"10.1093\/brain\/114.4.1595","volume":"114","author":"RD Treede","year":"1991","unstructured":"Treede RD, Lankers J, Frieling A, Zangemeister WH, Kunze K, Bromm B . Cerebral potentials evoked by painful, laser stimuli in patients with syringomyelia. Brain 1991; 114 ((Part 4)): 1595\u20131607.","journal-title":"Brain"},{"key":"BFsc2016191_CR45","doi-asserted-by":"publisher","first-page":"3409","DOI":"10.1093\/brain\/awq244","volume":"133","author":"SM Hatem","year":"2010","unstructured":"Hatem SM, Attal N, Ducreux D, Gautron M, Parker F, Plaghki L et al. Clinical, functional and structural determinants of central pain in syringomyelia. Brain 2010; 133: 3409\u20133422.","journal-title":"Brain"},{"key":"BFsc2016191_CR46","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1111\/j.1460-9568.2009.06801.x","volume":"30","author":"S Wydenkeller","year":"2009","unstructured":"Wydenkeller S, Maurizio S, Dietz V, Halder P . Neuropathic pain in spinal cord injury: significance of clinical and electrophysiological measures. Eur J Neurosci 2009; 30: 91\u201399.","journal-title":"Eur J Neurosci"},{"key":"BFsc2016191_CR47","doi-asserted-by":"publisher","first-page":"598","DOI":"10.1016\/j.clinph.2011.07.038","volume":"123","author":"H Kumru","year":"2012","unstructured":"Kumru H, Soler D, Vidal J, Tormos JM, Pascual-Leone A, Valls-Sole J . Evoked potentials and quantitative thermal testing in spinal cord injury patients with chronic neuropathic pain. Clin Neurophysiol 2012; 123: 598\u2013604.","journal-title":"Clin Neurophysiol"},{"key":"BFsc2016191_CR48","doi-asserted-by":"publisher","first-page":"1393","DOI":"10.1212\/WNL.0b013e31828c2ed1","volume":"80","author":"A Ulrich","year":"2013","unstructured":"Ulrich A, Haefeli J, Blum J, Min K, Curt A . Improved diagnosis of spinal cord disorders with contact heat evoked potentials. Neurology 2013; 80: 1393\u20131399.","journal-title":"Neurology"},{"issue":"Suppl 1","key":"BFsc2016191_CR49","doi-asserted-by":"publisher","first-page":"S8","DOI":"10.1007\/s00586-009-1123-5","volume":"19","author":"PM Parizel","year":"2010","unstructured":"Parizel PM, van der Zijden T, Gaudino S, Spaepen M, Voormolen MH, Venstermans C et al. Trauma of the spine and spinal cord: imaging strategies. Eur Spine J 2010; 19 (Suppl 1):S8\u201317.","journal-title":"Eur Spine J"},{"key":"BFsc2016191_CR50","doi-asserted-by":"publisher","first-page":"334","DOI":"10.1007\/s11940-014-0334-1","volume":"17","author":"RA Grant","year":"2015","unstructured":"Grant RA, Quon JL, Abbed KM . Management of acute traumatic spinal cord injury. Curr Treat Options Neurol 2015; 17: 334.","journal-title":"Curr Treat Options Neurol"},{"key":"BFsc2016191_CR51","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1097\/RMR.0000000000000069","volume":"24","author":"M Gold","year":"2015","unstructured":"Gold M . Magnetic resonance imaging of spinal emergencies. Top Magn Reson Imag 2015; 24: 325\u2013330.","journal-title":"Top Magn Reson Imag"},{"key":"BFsc2016191_CR52","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1016\/j.brainres.2013.10.007","volume":"1540","author":"EJ Yoon","year":"2013","unstructured":"Yoon EJ, Kim YK, Shin HI, Lee Y, Kim SE . Cortical and white matter alterations in patients with neuropathic pain after spinal cord injury. Brain Res 2013; 1540: 64\u201373.","journal-title":"Brain Res"},{"key":"BFsc2016191_CR53","doi-asserted-by":"publisher","first-page":"18534","DOI":"10.1038\/srep18534","volume":"6","author":"CR Jutzeler","year":"2016","unstructured":"Jutzeler CR, Huber E, Callaghan MF, Luechinger R, Curt A, Kramer JL et al. Association of pain and CNS structural changes after spinal cord injury. Sci Rep 2016; 6: 18534.","journal-title":"Sci Rep"},{"key":"BFsc2016191_CR54","doi-asserted-by":"publisher","first-page":"1443","DOI":"10.1002\/ejp.867","volume":"20","author":"G Landmann","year":"2016","unstructured":"Landmann G, Lustenberger C, Schleinzer W, Schmelz M, Stockinger L, Rukwied R . Short lasting transient effects of a capsaicin 8% patch on nociceptor activation in humans. Eur J Pain 2016; 20: 1443\u20131453.","journal-title":"Eur J Pain"},{"key":"BFsc2016191_CR55","doi-asserted-by":"publisher","first-page":"1256","DOI":"10.1016\/j.clinph.2010.02.159","volume":"121","author":"M Rage","year":"2010","unstructured":"Rage M, Van Acker N, Facer P, Shenoy R, Knaapen MW, Timmers M et al. The time course of CO2 laser-evoked responses and of skin nerve fibre markers after topical capsaicin in human volunteers. Clin Neurophysiol 2010; 121: 1256\u20131266.","journal-title":"Clin Neurophysiol"},{"key":"BFsc2016191_CR56","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1016\/0304-3959(95)00161-1","volume":"65","author":"A Beydoun","year":"1996","unstructured":"Beydoun A, Dyke DB, Morrow TJ, Casey KL . Topical capsaicin selectively attenuates heat pain and A delta fiber-mediated laser-evoked potentials. Pain 1996; 65: 189\u2013196.","journal-title":"Pain"},{"key":"BFsc2016191_CR57","doi-asserted-by":"publisher","first-page":"222","DOI":"10.1016\/j.ejpain.2009.05.001","volume":"14","author":"A Truini","year":"2010","unstructured":"Truini A, Panuccio G, Galeotti F, Maluccio MR, Sartucci F, Avoli M et al. Laser-evoked potentials as a tool for assessing the efficacy of antinociceptive drugs. Eur J Pain 2010; 14: 222\u2013225.","journal-title":"Eur J Pain"},{"key":"BFsc2016191_CR58","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1111\/bcp.12137","volume":"77","author":"LP Malver","year":"2014","unstructured":"Malver LP, Brokjaer A, Staahl C, Graversen C, Andresen T, Drewes AM . Electroencephalography and analgesics. Br J Clin Pharmacol 2014; 77: 72\u201395.","journal-title":"Br J Clin Pharmacol"},{"key":"BFsc2016191_CR59","doi-asserted-by":"publisher","first-page":"514","DOI":"10.1016\/S0168-5597(97)00064-6","volume":"104","author":"J Lorenz","year":"1997","unstructured":"Lorenz J, Beck H, Bromm B . Differential changes of laser evoked potentials, late auditory evoked potentials and P300 under morphine in chronic pain patients. Electroencephalogr Clin Neurophysiol 1997; 104: 514\u2013521.","journal-title":"Electroencephalogr Clin Neurophysiol"},{"key":"BFsc2016191_CR60","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1016\/S0304-3959(97)00123-1","volume":"73","author":"J Lorenz","year":"1997","unstructured":"Lorenz J, Beck H, Bromm B . Cognitive performance, mood and experimental pain before and during morphine-induced analgesia in patients with chronic non-malignant pain. Pain 1997; 73: 369\u2013375.","journal-title":"Pain"},{"key":"BFsc2016191_CR61","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1212\/WNL.0b013e3181ccc6ef","volume":"74","author":"DM Simpson","year":"2010","unstructured":"Simpson DM, Schifitto G, Clifford DB, Murphy TK, Durso-De Cruz E, Glue P et al. Pregabalin for painful HIV neuropathy: a randomized, double-blind, placebo-controlled trial. Neurology 2010; 74: 413\u2013420.","journal-title":"Neurology"},{"key":"BFsc2016191_CR62","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1002\/ejp.703","volume":"20","author":"T Mainka","year":"2016","unstructured":"Mainka T, Malewicz NM, Baron R, Enax-Krumova EK, Treede RD, Maier C . Presence of hyperalgesia predicts analgesic efficacy of topically applied capsaicin 8% in patients with peripheral neuropathic pain. Eur J Pain 2016; 20: 116\u2013129.","journal-title":"Eur J Pain"},{"key":"BFsc2016191_CR63","doi-asserted-by":"publisher","first-page":"911","DOI":"10.1111\/pme.12606","volume":"16","author":"Y Zhang","year":"2015","unstructured":"Zhang Y, Ahmed S, Vo T St, Hilaire K, Houghton M, Cohen AS et al. Increased pain sensitivity in chronic pain subjects on opioid therapy: a cross-sectional study using quantitative sensory testing. Pain Med 2015; 16: 911\u2013922.","journal-title":"Pain Med"},{"key":"BFsc2016191_CR64","doi-asserted-by":"publisher","first-page":"1810","DOI":"10.1097\/j.pain.0000000000000588","volume":"157","author":"J Vollert","year":"2016","unstructured":"Vollert J, Kramer M, Barroso A, Freynhagen R, Haanpaa M, Hansson P et al. Symptom profiles in the painDETECT Questionnaire in patients with peripheral neuropathic pain stratified according to sensory loss in quantitative sensory testing. Pain 2016; 157: 1810\u20131818.","journal-title":"Pain"}],"container-title":["Spinal Cord"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/sc2016191.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/sc2016191","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/doifinder\/10.1038\/sc.2016.191","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/www.nature.com\/articles\/sc2016191.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,20]],"date-time":"2023-05-20T22:31:19Z","timestamp":1684621879000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/sc2016191"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1,24]]},"references-count":64,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2017,6]]}},"alternative-id":["BFsc2016191"],"URL":"https:\/\/doi.org\/10.1038\/sc.2016.191","relation":{},"ISSN":["1362-4393","1476-5624"],"issn-type":[{"value":"1362-4393","type":"print"},{"value":"1476-5624","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,1,24]]},"assertion":[{"value":"2 May 2016","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 December 2016","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 December 2016","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 January 2017","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no conflict of interest.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}