{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T13:53:44Z","timestamp":1761746024889,"version":"3.27.0"},"reference-count":0,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2001,1,1]],"date-time":"2001-01-01T00:00:00Z","timestamp":978307200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2001,1,1]]},"abstract":"<jats:sec>\n<jats:title>OBJECTIVES<\/jats:title>\n<jats:p>To determine in vitro the potential of high-resolution MRI for evaluating the depth of tumor invasion of the tongue.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>METHODS<\/jats:title>\n<jats:p>Twenty-one resected specimens of squamous cell carcinoma of the tongue were examined on a 1.5T MRI system with a 4 cm surface coil using four different sequences; T1W SE, T2W SE, 3D-FISP and 3D-CISS. The thickness of normal epithelium, tumor depth and width were measured on both MR images and histopathological sections.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>RESULTS<\/jats:title>\n<jats:p>The mucosal epithelium, lamina propria and muscles of the tongue were clearly identifiable on MRI. All 21 carcinomas, including three early invasive carcinomas, were clearly demonstrated. A high correlation was found between the values measured by MRI and histopathology for thickness of mucosal epithelium and both depth and width of tumors. There was a good agreement between the T2W SE and the other imaging sequences for measurements of both depth and width of tumors.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>CONCLUSION<\/jats:title>\n<jats:p>High-resolution MR imaging appears reliable for the in vitro evaluation of depth of tumor invasion in carcinoma of the tongue.<\/jats:p>\n<\/jats:sec>","DOI":"10.1038\/sj\/dmfr\/4600565","type":"journal-article","created":{"date-parts":[[2024,10,18]],"date-time":"2024-10-18T10:47:44Z","timestamp":1729248464000},"page":"14-21","source":"Crossref","is-referenced-by-count":3,"title":["High-resolution magnetic resonance imaging of squamous cell carcinoma of the tongue: an in vitro study"],"prefix":"10.1093","volume":"30","author":[{"given":"A","family":"Tetsumura","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillofacial Radiology , Graduate School, Tokyo Medical and Dental University, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N","family":"Yoshino","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Radiology , Graduate School, Tokyo Medical and Dental University, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T","family":"Amagasa","sequence":"additional","affiliation":[{"name":"Department of Maxillofacial Surgery , Graduate School, Tokyo Medical and Dental University, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K","family":"Nagumo","sequence":"additional","affiliation":[{"name":"Clinical Laboratory , University Dental Hospital, Tokyo Medical and Dental University, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N","family":"Okada","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Oral Pathology , Graduate School, Tokyo Medical and Dental University, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T","family":"Sasaki","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Radiology , Graduate School, Tokyo Medical and Dental University, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2014,5,29]]},"container-title":["Dentomaxillofacial Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/dmfr\/article-pdf\/30\/1\/14\/53520051\/sj_dmfr_4600565.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/dmfr\/article-pdf\/30\/1\/14\/53520051\/sj_dmfr_4600565.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,18]],"date-time":"2024-10-18T14:23:39Z","timestamp":1729261419000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/dmfr\/article\/30\/1\/14\/7267326"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,1,1]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2001,1,1]]}},"URL":"https:\/\/doi.org\/10.1038\/sj\/dmfr\/4600565","relation":{},"ISSN":["0250-832X","1476-542X"],"issn-type":[{"value":"0250-832X","type":"print"},{"value":"1476-542X","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2001,1,1]]},"published":{"date-parts":[[2001,1,1]]}}}