{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T13:23:54Z","timestamp":1760189034120},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2008,12,1]],"date-time":"2008-12-01T00:00:00Z","timestamp":1228089600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br Dent J"],"published-print":{"date-parts":[[2008,12]]},"DOI":"10.1038\/sj.bdj.2008.1080","type":"journal-article","created":{"date-parts":[[2008,12,19]],"date-time":"2008-12-19T10:53:13Z","timestamp":1229683993000},"page":"649-652","source":"Crossref","is-referenced-by-count":17,"title":["A study of patients attending a multidisciplinary hypodontia clinic over a five year period"],"prefix":"10.1038","volume":"205","author":[{"given":"I.","family":"Shafi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. M.","family":"Phillips","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. P.","family":"Dawson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. D.","family":"Broad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. T.","family":"Hosey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2008,12,20]]},"reference":[{"key":"BFsjbdj20081080_CR1","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1038\/sj.bdj.4809925","volume":"194","author":"JH Nunn","year":"2003","unstructured":"Nunn J H, Carter N E, Gillgrass T J et al. The interdisciplinary management of hypodontia: background and role of paediatric dentistry. Br Dent J 2003; 194: 245\u2013251.","journal-title":"Br Dent J"},{"key":"BFsjbdj20081080_CR2","first-page":"1","volume":"7(3)","author":"H Grahnen","year":"1956","unstructured":"Grahnen H . Hypodontia in the permanent dentition. A clinical and genetical investigation. Odont Revy 1956; 7(3): 1\u2013100.","journal-title":"Odont Revy"},{"key":"BFsjbdj20081080_CR3","first-page":"95","volume":"19","author":"NJ Burzynski","year":"1983","unstructured":"Burzynski N J, Escobar V H . Classification and genetics of numeric anomalies of dentition. Birth Defects Orig Artic Ser 1983; 19: 95\u2013106.","journal-title":"Birth Defects Orig Artic Ser"},{"key":"BFsjbdj20081080_CR4","first-page":"212","volume":"21","author":"JF Gravely","year":"1971","unstructured":"Gravely J F, Johnson D B . Variation in the expression of hypodontia in monozygotic twins. Dent Pract Dent Rec 1971; 21: 212\u2013220.","journal-title":"Dent Pract Dent Rec"},{"key":"BFsjbdj20081080_CR5","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1016\/0002-9416(71)90032-7","volume":"60","author":"MJ Boruchov","year":"1971","unstructured":"Boruchov M J, Green L J . Hypodontia in human twins and families. Am J Orthod 1971; 60: 165\u2013174.","journal-title":"Am J Orthod"},{"key":"BFsjbdj20081080_CR6","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1016\/0003-9969(84)90163-8","volume":"29","author":"AH Brook","year":"1984","unstructured":"Brook A H . A unifying aetiological explanation for anomalies of human tooth number and size. Arch Oral Biol 1984; 29: 373\u2013378.","journal-title":"Arch Oral Biol"},{"key":"BFsjbdj20081080_CR7","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3109\/00016356309011238","volume":"21","author":"A Bohn","year":"1963","unstructured":"Bohn A . Dental anomalies in harelip and cleft palate. Acta Odontol Scand 1963; 21: 1\u2013109.","journal-title":"Acta Odontol Scand"},{"key":"BFsjbdj20081080_CR8","first-page":"1","volume":"68","author":"R Ranta","year":"1972","unstructured":"Ranta R . The development of the permanent teeth in children with complete cleft lip and palate. Proc Finn Dent Soc 1972; 68: 1\u201327.","journal-title":"Proc Finn Dent Soc"},{"key":"BFsjbdj20081080_CR9","doi-asserted-by":"publisher","first-page":"396","DOI":"10.1016\/S0889-5406(99)70258-1","volume":"115","author":"Y Shapira","year":"1999","unstructured":"Shapira Y, Lubit E, Kuftinec M M . Congenitally missing second premolars in cleft lip and cleft palate children. Am J Orthod Dentofacial Orthop 1999; 115: 396\u2013400.","journal-title":"Am J Orthod Dentofacial Orthop"},{"key":"BFsjbdj20081080_CR10","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1038\/ng0896-417","volume":"13","author":"H Vastardis","year":"1996","unstructured":"Vastardis H, Karimbux N, Guthua S W et al. A human MSX1 homeodomain missense mutation causes selective tooth agenesis. Nat Genet 1996; 13: 417\u2013421.","journal-title":"Nat Genet"},{"key":"BFsjbdj20081080_CR11","doi-asserted-by":"publisher","first-page":"342","DOI":"10.1038\/74155","volume":"24","author":"MJ van den Boogaard","year":"2000","unstructured":"van den Boogaard M J, Dorland M, Beemer F A et al. MSX1 mutation is associated with orofacial clefting and tooth agenesis in humans. Nat Genet 2000; 24: 342\u2013343.","journal-title":"Nat Genet"},{"key":"BFsjbdj20081080_CR12","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1038\/71634","volume":"24","author":"DW Stockton","year":"2000","unstructured":"Stockton D W, Das P, Goldenberg M et al. Mutation of PAX9 is associated with oligodontia. Nat Genet 2000; 24: 18\u201319.","journal-title":"Nat Genet"},{"key":"BFsjbdj20081080_CR13","doi-asserted-by":"publisher","first-page":"274","DOI":"10.1177\/154405910208100410","volume":"81","author":"AC Lidral","year":"2002","unstructured":"Lidral A C, Reising B C . The role of MSX1 in human tooth agenesis. J Dent Res 2002; 81: 274\u2013278.","journal-title":"J Dent Res"},{"key":"BFsjbdj20081080_CR14","doi-asserted-by":"publisher","first-page":"723","DOI":"10.1177\/154405910408300913","volume":"83","author":"AR Vieira","year":"2004","unstructured":"Vieira A R, Meira R, Modesto A et al. MSX1, PAX9, and TGFA contribute to tooth agenesis in humans. J Dent Res 2004; 83: 723\u2013727.","journal-title":"J Dent Res"},{"key":"BFsjbdj20081080_CR15","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1038\/bdj.2007.732","volume":"203","author":"MT Cobourne","year":"2007","unstructured":"Cobourne M T . Familial human hypodontia \u2013 is it all in the genes? Br Dent J 2007; 203: 203\u2013208.","journal-title":"Br Dent J"},{"key":"BFsjbdj20081080_CR16","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1038\/sj.bdj.4810184","volume":"194","author":"RS Hobson","year":"2003","unstructured":"Hobson R S, Carter N E, Gillgrass T J et al. The interdisciplinary management of hypodontia: the relationship between an interdisciplinary team and the general dental practitioner. Br Dent J 2003; 194: 479\u2013482.","journal-title":"Br Dent J"},{"key":"BFsjbdj20081080_CR17","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1111\/j.1365-2842.1980.tb00447.x","volume":"7","author":"JA Hobkirk","year":"1980","unstructured":"Hobkirk J A, Brook A H . The management of patients with severe hypodontia. J Oral Rehabil 1980; 7: 289\u2013298.","journal-title":"J Oral Rehabil"},{"key":"BFsjbdj20081080_CR18","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1038\/sj.bdj.4808606","volume":"177","author":"JA Hobkirk","year":"1994","unstructured":"Hobkirk J A, Goodman J R, Jones S P . Presenting complaints and findings in a group of patients attending a hypodontia clinic. Br Dent J 1994; 177: 337\u2013339.","journal-title":"Br Dent J"},{"key":"BFsjbdj20081080_CR19","volume-title":"Carstairs scores for Scottish postcode sectors from the 2001 Census Report","author":"P McLoone","year":"2004","unstructured":"McLoone P . Carstairs scores for Scottish postcode sectors from the 2001 Census Report. Glasgow: MRC Social & Public Health Sciences Unit, 2004."},{"key":"BFsjbdj20081080_CR20","doi-asserted-by":"publisher","first-page":"101","DOI":"10.14219\/jada.archive.1970.0151","volume":"81","author":"TP Muller","year":"1970","unstructured":"Muller T P, Hill I N, Peterson A C et al. A survey of congenitally missing teeth. J Am Dent Assoc 1970; 81: 101\u2013107.","journal-title":"J Am Dent Assoc"},{"key":"BFsjbdj20081080_CR21","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1177\/00220345440230020401","volume":"23","author":"PJ Brekhus","year":"1944","unstructured":"Brekhus P J, Oliver C P, Montelius G . A study of the pattern and combinations of congenitally missing teeth in man. J Dent Res 1944; 23: 117\u2013131.","journal-title":"J Dent Res"},{"key":"BFsjbdj20081080_CR22","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1179\/bjo.11.1.9","volume":"11","author":"IM Clow","year":"1984","unstructured":"Clow I M . A radiographic survey of third molar development: a comparison. Br J Orthod 1984; 11: 9\u201315.","journal-title":"Br J Orthod"},{"key":"BFsjbdj20081080_CR23","first-page":"121","volume":"50","author":"M Richardson","year":"1980","unstructured":"Richardson M . Late third molar genesis: its significance in orthodontic treatment. Angle Orthod 1980; 50: 121\u2013128.","journal-title":"Angle Orthod"},{"key":"BFsjbdj20081080_CR24","first-page":"31","volume":"63","author":"YS Van der Weide","year":"1993","unstructured":"Van der Weide Y S, Prahl-Andersen B, Bosman F . Tooth formation in patients with oligodontia. Angle Orthod 1993; 63: 31\u201337.","journal-title":"Angle Orthod"},{"key":"BFsjbdj20081080_CR25","first-page":"51","volume":"40","author":"SM Garn","year":"1970","unstructured":"Garn S M, Lewis A B . The gradient and the pattern of crown size and reduction in simple hypodontia. Angle Orthod 1970; 40: 51\u201357.","journal-title":"Angle Orthod"},{"key":"BFsjbdj20081080_CR26","first-page":"316","volume":"44","author":"B Rune","year":"1974","unstructured":"Rune B, Sarnas K . Tooth size and tooth formation in children with advanced hypodontia. Angle Orthod 1974; 44: 316\u2013321.","journal-title":"Angle Orthod"},{"key":"BFsjbdj20081080_CR27","unstructured":"Faculty of Dental Surgery of the Royal College of Surgeons of England. Guidelines for selecting appropriate patients to receive treatment with dental implants: priorities for the NHS. London: RCSE, 1997."},{"key":"BFsjbdj20081080_CR28","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1038\/sj.bdj.4809940","volume":"194","author":"NJ Jepson","year":"2003","unstructured":"Jepson N J, Nohl F S, Carter N E et al. The interdisciplinary management of hypodontia: restorative dentistry. Br Dent J 2003; 194: 299\u2013304.","journal-title":"Br Dent J"}],"container-title":["British Dental Journal"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/sj.bdj.2008.1080.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/sj.bdj.2008.1080","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/sj.bdj.2008.1080.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,20]],"date-time":"2023-05-20T22:33:50Z","timestamp":1684622030000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/sj.bdj.2008.1080"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,12]]},"references-count":28,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2008,12]]}},"alternative-id":["BFsjbdj20081080"],"URL":"https:\/\/doi.org\/10.1038\/sj.bdj.2008.1080","relation":{},"ISSN":["0007-0610","1476-5373"],"issn-type":[{"value":"0007-0610","type":"print"},{"value":"1476-5373","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,12]]}}}