{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T23:37:41Z","timestamp":1790811461695,"version":"4.1.0"},"reference-count":35,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Br Dent J"],"published-print":{"date-parts":[[2019,1]]},"DOI":"10.1038\/sj.bdj.2019.4","type":"journal-article","created":{"date-parts":[[2019,1,11]],"date-time":"2019-01-11T08:55:56Z","timestamp":1547196956000},"page":"27-31","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["Oral manifestations of sickle cell disease"],"prefix":"10.1038","volume":"226","author":[{"given":"M.","family":"Chekroun","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Ch\u00e9rifi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Fournier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Gaultier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.-Y.","family":"Sitbon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F. C\u00f4me","family":"Ferr\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Gogly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,1,11]]},"reference":[{"key":"BFsjbdj20194_CR1","doi-asserted-by":"publisher","first-page":"1459","DOI":"10.1016\/S0140-6736(16)31012-1","volume":"388","author":"GBD Mortality","year":"2016","unstructured":"Mortality G B D, Causes of Death C . Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980\u20132015: a systematic analysis for the Global Burden of Disease Study 2015. Lancet 2016; 388: 1459\u20131544.","journal-title":"Lancet"},{"key":"BFsjbdj20194_CR2","doi-asserted-by":"publisher","first-page":"2018","DOI":"10.1016\/S0140-6736(10)61029-X","volume":"376","author":"DC Rees","year":"2010","unstructured":"Rees D C, Williams T N, Gladwin M T . Sickle-cell disease. Lancet 2010; 376: 2018\u20132031.","journal-title":"Lancet"},{"key":"BFsjbdj20194_CR3","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1097\/MOH.0b013e328351c35f","volume":"19","author":"P Bartolucci","year":"2012","unstructured":"Bartolucci P, Galacteros F . Clinical management of adult sickle-cell disease. Curr Opin Haematol 2012; 19: 149\u2013155.","journal-title":"Curr Opin Haematol"},{"key":"BFsjbdj20194_CR4","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1111\/j.1365-2141.2009.08054.x","volume":"149","author":"K Ryan","year":"2010","unstructured":"Ryan K, Bain B J, Worthington D et al. Significant haemoglobinopathies: guidelines for screening and diagnosis. Br J Haematol 2010; 149: 35\u201349.","journal-title":"Br J Haematol"},{"key":"BFsjbdj20194_CR5","unstructured":"NHS Sickle Cell and Thalassaemia Screening Programme. Screening for Sickle Cell and Thalassaemia. 2012. Available at \n                    https:\/\/www.gov.uk\/government\/collections\/sickle-cell-and-thalassaemia-screening-commission-and-provide\n                    \n                   (accessed December 2018)."},{"key":"BFsjbdj20194_CR6","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1016\/j.disamonth.2017.12.003","volume":"64","author":"S Alrayyes","year":"2018","unstructured":"Alrayyes S, Baghdan D, Haddad R Y et al. Sickle cell disease; An overview of the disease and its systemic effects. Dis Mon 2018; 64: 283\u2013289.","journal-title":"Dis Mon"},{"key":"BFsjbdj20194_CR7","first-page":"CD011633","volume":"4","author":"P Mulimani","year":"2016","unstructured":"Mulimani P, Ballas S K, Abas A B, Karanth L . Treatment of dental complications in sickle cell disease. Cochrane Database Syst Rev 2016; 4: CD011633.","journal-title":"Cochrane Database Syst Rev"},{"key":"BFsjbdj20194_CR8","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1182\/blood-2013-05-498311","volume":"122","author":"D Manwani","year":"2013","unstructured":"Manwani D, Frenette P S . Vaso-occlusion in sickle cell disease: pathophysiology and novel targeted therapies. Blood 2013; 122: 3, 892\u2013898.","journal-title":"Blood"},{"key":"BFsjbdj20194_CR9","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.clinimag.2017.09.001","volume":"48","author":"MX Wang","year":"2018","unstructured":"Wang M X, Pepin E W, Verma N, Mohammed T L . Manifestations of sickle cell disease on thoracic imaging. Clin Imaging 2018; 48: 1\u20136.","journal-title":"Clin Imaging"},{"key":"BFsjbdj20194_CR10","first-page":"CD004198","volume":"9","author":"FI Chinegwundoh","year":"2017","unstructured":"Chinegwundoh F I, Smith S, Anie K A . Treatments for priapism in boys and men with sickle cell disease. Cochrane Database Syst Rev 2017; 9: CD004198.","journal-title":"Cochrane Database Syst Rev"},{"key":"BFsjbdj20194_CR11","first-page":"CD003427","volume":"10","author":"AE Rankine-Mullings","year":"2017","unstructured":"Rankine-Mullings A E, Owusu-Ofori S . Prophylactic antibiotics for preventing pneumococcal infection in children with sickle cell disease. Cochrane Database Syst Rev 2017; 10: CD003427.","journal-title":"Cochrane Database Syst Rev"},{"key":"BFsjbdj20194_CR12","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1182\/asheducation-2017.1.435","volume":"2017","author":"E Vichinsky","year":"2017","unstructured":"Vichinsky E . Chronic organ failure in adult sickle cell disease. Haematology Am Soc Haematol Educ Program 2017; 2017: 435\u2013439.","journal-title":"Haematology Am Soc Haematol Educ Program"},{"key":"BFsjbdj20194_CR13","doi-asserted-by":"publisher","first-page":"1075","DOI":"10.1007\/s11255-018-1803-3","volume":"50","author":"E Hariri","year":"2018","unstructured":"Hariri E, Mansour A, El Alam A et al. Sickle cell nephropathy: an update on pathophysiology, diagnosis, and treatment. Int Urol Nephrol 2018; 50: 1075\u20131083.","journal-title":"Int Urol Nephrol"},{"key":"BFsjbdj20194_CR14","doi-asserted-by":"publisher","first-page":"731","DOI":"10.1002\/jbmr.3026","volume":"32","author":"K Steer","year":"2017","unstructured":"Steer K, Stavnichuk M, Morris M, Komarova S V . Bone Health in Patients With Haematopoietic Disorders of Bone Marrow Origin: Systematic Review and MetaAnalysis. J Bone Miner Res 2017; 32: 731\u2013742.","journal-title":"J Bone Miner Res"},{"key":"BFsjbdj20194_CR15","first-page":"701","volume":"42","author":"PH Mendes","year":"2011","unstructured":"Mendes P H, Fonseca N G, Martelli D R et al. Orofacial manifestations in patients with sickle cell anaemia. Quintessence Int 2011; 42: 701\u2013709.","journal-title":"Quintessence Int"},{"key":"BFsjbdj20194_CR16","doi-asserted-by":"publisher","first-page":"1042","DOI":"10.1016\/j.archoralbio.2014.05.014","volume":"59","author":"BM de Matos","year":"2014","unstructured":"de Matos B M, Ribeiro Z E, Balducci I et al. Oral microbial colonization in children with sickle cell anaemia under long-term prophylaxis with penicillin. Arch Oral Biol 2014; 59: 1042\u20131047.","journal-title":"Arch Oral Biol"},{"key":"BFsjbdj20194_CR17","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1016\/j.joen.2012.10.024","volume":"39","author":"CP Costa","year":"2013","unstructured":"Costa C P, Thomaz E B, Souza Sde F . Association between Sickle Cell Anaemia and Pulp Necrosis. J Endod 2013; 39: 177\u2013181.","journal-title":"J Endod"},{"key":"BFsjbdj20194_CR18","first-page":"159","volume":"29","author":"M da Fonseca","year":"2007","unstructured":"da Fonseca M, Oueis H S, Casamassimo P S . Sickle cell anaemia: a review for the paediatric dentist. Paediatr Dent 2007; 29: 159\u2013169.","journal-title":"Paediatr Dent"},{"key":"BFsjbdj20194_CR19","first-page":"269","volume":"76","author":"PV Alves","year":"2006","unstructured":"Alves P V, Alves DK, de Souza M M, Torres S R . Orthodontic treatment of patients with sickle-cell anaemia. Angle Orthod 2006; 76: 269\u2013273.","journal-title":"Angle Orthod"},{"key":"BFsjbdj20194_CR20","doi-asserted-by":"publisher","first-page":"468","DOI":"10.1111\/j.1600-0714.1995.tb01136.x","volume":"24","author":"EA Field","year":"1995","unstructured":"Field E A, Speechley J A, Rugman F R, Varga E, Tyldesley W R . Oral signs and symptoms in patients with undiagnosed vitamin B12 deficiency. J Oral Pathol Med 1995; 24: 468\u2013470.","journal-title":"J Oral Pathol Med"},{"key":"BFsjbdj20194_CR21","doi-asserted-by":"publisher","first-page":"622","DOI":"10.1111\/jre.12342","volume":"51","author":"HL de Carvalho","year":"2016","unstructured":"de Carvalho H L, Thomaz E B, Alves C M, Souza S F . Are sickle cell anaemia and sickle cell trait predictive factors for periodontal disease? A cohort study. J Periodontal Res 2016; 51: 622\u2013629.","journal-title":"J Periodontal Res"},{"key":"BFsjbdj20194_CR22","doi-asserted-by":"publisher","first-page":"306","DOI":"10.1034\/j.1601-0825.2001.3600723a.x","volume":"7","author":"JE Scipio","year":"2001","unstructured":"Scipio J E, Al-Bayaty H F, Murti P R, Matthews R . Facial swelling and gingival enlargement in a patient with sickle cell disease. Oral Dis 2001; 7: 306\u2013309.","journal-title":"Oral Dis"},{"key":"BFsjbdj20194_CR23","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1007\/s10266-004-0036-3","volume":"92","author":"S Kavadia-Tsatala","year":"2004","unstructured":"Kavadia-Tsatala S, Kolokytha O, Kaklamanos E G, Antoniades K, Chasapopoulou E . Mandibular lesions of vasoocclusive origin in sickle cell haemoglobinopathy. Odontology 2004; 92: 68\u201372.","journal-title":"Odontology"},{"key":"BFsjbdj20194_CR24","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1111\/j.1754-4505.1995.tb00469.x","volume":"15","author":"LB Taylor","year":"1995","unstructured":"Taylor L B, Nowak A J, Giller R H, Casamassimo P S . Sickle cell anaemia: a review of the dental concerns and a retrospective study of dental and bony changes. Spec Care Dentist 1995; 15: 38\u201342.","journal-title":"Spec Care Dentist"},{"key":"BFsjbdj20194_CR25","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1016\/S0266-4356(97)90562-3","volume":"35","author":"AA Olaitan","year":"1997","unstructured":"Olaitan A A, Amuda J T, Adekeye E O . Osteomyelitis of the mandible in sickle cell disease. Br J Oral Maxillofac Surg 1997; 35: 190\u2013192.","journal-title":"Br J Oral Maxillofac Surg"},{"key":"BFsjbdj20194_CR26","doi-asserted-by":"publisher","first-page":"20160130","DOI":"10.1259\/bjr.20160130","volume":"90","author":"V Kosaraju","year":"2017","unstructured":"Kosaraju V, Harwani A, Partovi S et al. Imaging of musculoskeletal manifestations in sickle cell disease patients. Br J Radiol 2017; 90: 20160130.","journal-title":"Br J Radiol"},{"key":"BFsjbdj20194_CR27","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1016\/S1079-2104(96)80261-7","volume":"82","author":"M Kelleher","year":"1996","unstructured":"Kelleher M, Bishop K, Briggs P . Oral complications associated with sickle cell anaemia: a review and case report. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1996; 82: 225\u2013228.","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"BFsjbdj20194_CR28","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1016\/0030-4220(80)90025-0","volume":"49","author":"AH Friedlander","year":"1980","unstructured":"Friedlander A H, Genser L, Swerdloff M . Mental nerve neuropathy: a complication of sickle-cell crisis. Oral Surg Oral Med Oral Pathol 1980; 49: 15\u201317.","journal-title":"Oral Surg Oral Med Oral Pathol"},{"issue":"5 Suppl 1","key":"BFsjbdj20194_CR29","doi-asserted-by":"publisher","first-page":"5S3","DOI":"10.1016\/S0248-8663(15)60002-9","volume":"36","author":"A Habibi","year":"2015","unstructured":"Habibi A, Arlet J B, Stankovic K et al. French guidelines for the management of adult sickle cell disease: 2015 update. Rev Med Interne. 2015; 36 (5 Suppl 1): 5S3\u20135S84.","journal-title":"Rev Med Interne."},{"key":"BFsjbdj20194_CR30","doi-asserted-by":"publisher","first-page":"141","DOI":"10.5005\/jp-journals-10005-1301","volume":"8","author":"S Acharya","year":"2015","unstructured":"Acharya S . Oral and Dental Considerations in Management of Sickle Cell Anaemia. Int J Clin Paediatr Dent 2015; 8: 141\u2013144.","journal-title":"Int J Clin Paediatr Dent"},{"key":"BFsjbdj20194_CR31","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1016\/S0278-2391(99)90234-3","volume":"57","author":"DR Lawrenz","year":"1999","unstructured":"Lawrenz D R . Sickle cell disease: a review and update of current therapy. J Oral Maxillofac Surg 1999; 57: 171\u2013178.","journal-title":"J Oral Maxillofac Surg"},{"key":"BFsjbdj20194_CR32","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1111\/j.1365-263X.1996.tb00250.x","volume":"6","author":"MS Duggal","year":"1996","unstructured":"Duggal M S, Bedi R, Kinsey S E, Williams S A . The dental management of children with sickle cell disease and beta-thalassaemia: a review. Int J Paediatr Dent 1996; 6: 227\u2013234.","journal-title":"Int J Paediatr Dent"},{"key":"BFsjbdj20194_CR33","doi-asserted-by":"publisher","first-page":"912","DOI":"10.1016\/S0278-2391(10)80114-4","volume":"51","author":"JJ Sansevere","year":"1993","unstructured":"Sansevere J J, Milles M . Management of the oral and maxillofacial surgery patient with sickle cell disease and related haemoglobinopathies. J Oral Maxillofac Surg 1993; 51: 912\u2013916.","journal-title":"J Oral Maxillofac Surg"},{"key":"BFsjbdj20194_CR34","doi-asserted-by":"publisher","first-page":"1027","DOI":"10.1016\/j.joms.2012.12.004","volume":"71","author":"AC Stanley","year":"2013","unstructured":"Stanley A C, Christian J M . Sickle cell disease and perioperative considerations: review and retrospective report. J Oral Maxillofac Surg 2013; 71: 1027\u20131033.","journal-title":"J Oral Maxillofac Surg"},{"key":"BFsjbdj20194_CR35","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1016\/j.jds.2011.09.008","volume":"6","author":"ETH Guzeldemir","year":"2011","unstructured":"Guzeldemir E T H, Boga C, Cilasun U . Dental and periodontal health status of subjects with sickle cell disease. J Dent Sci 2011; 6: 227\u2013234.","journal-title":"J Dent Sci"}],"container-title":["British Dental Journal"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/sj.bdj.2019.4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/sj.bdj.2019.4","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/doifinder\/10.1038\/sj.bdj.2019.4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/www.nature.com\/articles\/sj.bdj.2019.4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,20]],"date-time":"2023-05-20T22:46:25Z","timestamp":1684622785000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/sj.bdj.2019.4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1]]},"references-count":35,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,1]]}},"alternative-id":["BFsjbdj20194"],"URL":"https:\/\/doi.org\/10.1038\/sj.bdj.2019.4","relation":{},"ISSN":["0007-0610","1476-5373"],"issn-type":[{"value":"0007-0610","type":"print"},{"value":"1476-5373","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,1]]},"assertion":[{"value":"14 September 2018","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 January 2019","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}