{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T14:45:42Z","timestamp":1792680342497,"version":"4.5.0"},"reference-count":128,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[1999,3,1]],"date-time":"1999-03-01T00:00:00Z","timestamp":920246400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br Dent J"],"published-print":{"date-parts":[[1999,3]]},"DOI":"10.1038\/sj.bdj.4800090","type":"journal-article","created":{"date-parts":[[2009,3,2]],"date-time":"2009-03-02T11:06:45Z","timestamp":1235992005000},"page":"286-296","source":"Crossref","is-referenced-by-count":19,"title":["Antibacterial agents in the control of supragingival plaque \u2014 a review"],"prefix":"10.1038","volume":"186","author":[{"given":"B M","family":"Eley","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[1999,3,27]]},"reference":[{"key":"BF4800090_CR1","doi-asserted-by":"publisher","first-page":"957","DOI":"10.1111\/j.1600-051X.1986.tb01434.x","volume":"13","author":"M Addy","year":"1986","unstructured":"Addy M . Chlorhexidine compared with other locally delivered antimicrobials. J Clin Periodontol 1986; 13: 957\u2013964.","journal-title":"J Clin Periodontol"},{"key":"BF4800090_CR2","first-page":"192","volume":"9","author":"G Davies","year":"1954","unstructured":"Davies G, Francis J, Martin A, Rose F, Swain G 1:6 Di-4'-chlorophenl-diguanidohexane. Laboratory investigation into a new antibacterial agent of high potency. Br J Pharmacol 1954; 9: 192\u2013196.","journal-title":"Br J Pharmacol"},{"key":"BF4800090_CR3","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1111\/j.1600-0765.1973.tb02166.x","volume":"8(suppl.)","author":"T Hennessy","year":"1973","unstructured":"Hennessy T . Some antibacterial properties of chlorhexidine. J Periodont Res 1973; 8(suppl.): 61\u201367.","journal-title":"J Periodont Res"},{"key":"BF4800090_CR4","first-page":"255","volume":"85","author":"C Emisilon","year":"1977","unstructured":"Emisilon C . Susceptibility of various microorganisms to chlorhexidine. Scand J Dent Res 1977; 85: 255\u2013265.","journal-title":"Scand J Dent Res"},{"key":"BF4800090_CR5","first-page":"457","volume":"80","author":"J Budtz-Jorgensen","year":"1972","unstructured":"Budtz-Jorgensen J, L\u00f6e H . Chlorhexidine as a denture disinfectant in the treatment of denture stomatitis. Scand J Dent Res 1972; 80: 457\u2013464.","journal-title":"Scand J Dent Res"},{"key":"BF4800090_CR6","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1111\/j.1600-051X.1977.tb00050.x","volume":"4","author":"T Hennessy","year":"1977","unstructured":"Hennessy T . Antibacterial properties of Hibitane. J Clin Periodontol 1977; 4: 36\u201348.","journal-title":"J Clin Periodontol"},{"key":"BF4800090_CR7","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1111\/j.1600-051X.1996.tb00547.x","volume":"23","author":"D Grenier","year":"1996","unstructured":"Grenier, D . Effect of chlorhexidine on the adherence properties of Porphyromonas gingivalis. J Clin Periodontol 1996; 23: 140\u2013142.","journal-title":"J Clin Periodontol"},{"key":"BF4800090_CR8","doi-asserted-by":"publisher","first-page":"431","DOI":"10.1111\/j.1600-051X.1980.tb02150.x","volume":"7","author":"P Hull","year":"1980","unstructured":"Hull P . Chemical inhibition of plaque. J Clin Periodontol 1980; 7: 431\u2013442.","journal-title":"J Clin Periodontol"},{"key":"BF4800090_CR9","doi-asserted-by":"publisher","first-page":"1109","DOI":"10.1016\/0003-9969(71)90215-9","volume":"16","author":"G R\u00f6lla","year":"1971","unstructured":"R\u00f6lla G, L\u00f6e H, Schi\u00f6t C . Retention of chlorhexidine in the human oral cavity. Arch Oral Biol 1971; 16: 1109\u20131116.","journal-title":"Arch Oral Biol"},{"key":"BF4800090_CR10","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1016\/0003-9969(78)90021-3","volume":"23","author":"P Bonesvoll","year":"1978","unstructured":"Bonesvoll P, Gjermo P . A comparison between chlorhexidine and some quaternary ammonium compounds with regard to retention, salivary concentration and plaque inhibitory effect in the human mouth after mouthrinses. Arch Oral Biol 1978; 23: 289\u2013294.","journal-title":"Arch Oral Biol"},{"key":"BF4800090_CR11","doi-asserted-by":"publisher","first-page":"1025","DOI":"10.1016\/0003-9969(74)90089-2","volume":"19","author":"P Bonesvoll","year":"1974","unstructured":"Bonesvoll P, L\u00f6kken P, R\u00f6lla G . Influence of concentration, time, temperature and pH on the retention of chlorhexidine in the human oral cavity after mouth rinses. Arch Oral Biol 1974; 19: 1025\u20131029.","journal-title":"Arch Oral Biol"},{"key":"BF4800090_CR12","doi-asserted-by":"publisher","first-page":"1031","DOI":"10.1016\/0003-9969(74)90090-9","volume":"19","author":"P Gjermo","year":"1974","unstructured":"Gjermo P, Bonesvoll P, R\u00f6lla G . Relationship between plaque inhibiting effect and the retention of chlorhexidine in the oral cavity. Arch Oral Biol 1974; 19: 1031\u20131034.","journal-title":"Arch Oral Biol"},{"key":"BF4800090_CR13","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1111\/j.1600-0765.1973.tb02163.x","volume":"12","author":"M Winrow","year":"1973","unstructured":"Winrow M . Metabolic studies with radiolabelled chlorhexidine in animals and man. J Periodont Res 1973; 12 (suppl.): 45\u201348.","journal-title":"J Periodont Res"},{"key":"BF4800090_CR14","first-page":"131","volume":"12 (suppl.)","author":"E Faulkes","year":"1973","unstructured":"Faulkes E . Some toxicological observations of chlorhexidine. J Periodont Res 1973; 12 (suppl.): 131\u2013148.","journal-title":"J Periodont Res"},{"key":"BF4800090_CR15","doi-asserted-by":"publisher","first-page":"830","DOI":"10.1111\/j.1600-051X.1995.tb01780.x","volume":"22","author":"A Binney","year":"1995","unstructured":"Binney A, Addy M, McKeown S, Everatt L . The effect of a commercially available triclosan-containing toothpaste compared to a sodium-fluoride-containing toothpaste and a chlorhexidine rinse on 4-day plaque regrowth. J Clin Periodontol 1995; 22: 830\u2013834.","journal-title":"J Clin Periodontol"},{"key":"BF4800090_CR16","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1111\/j.1600-051X.1993.tb01754.x","volume":"20","author":"S Jenkins","year":"1993","unstructured":"Jenkins S, Addy M, Newcombe R . Evaluation of a mouthrinse containing chlorhexidine and fluoride as an adjunct to oral hygiene. J Clin Periodontol 1993; 20: 20\u201325.","journal-title":"J Clin Periodontol"},{"key":"BF4800090_CR17","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1111\/j.1600-051X.1993.tb01759.x","volume":"20","author":"S Joyston-Bechal","year":"1993","unstructured":"Joyston-Bechal S, Hernaman N . The effect of a mouthrinse containing chlorhexidine and fluoride on plaque and gingival bleeding. J Clin Periodontol 1993; 20: 49\u201353.","journal-title":"J Clin Periodontol"},{"key":"BF4800090_CR18","doi-asserted-by":"publisher","first-page":"380","DOI":"10.1111\/j.1600-051X.1989.tb00008.x","volume":"16","author":"M Addy","year":"1989","unstructured":"Addy M, Jenkins S, Newcombe R . Studies of the effect of toothpaste rinses on plaque regrowth. (1) Influence of surfactants on chlorhexidine efficiency. J Clin Periodontol 1989; 16: 380\u2013384.","journal-title":"J Clin Periodontol"},{"key":"BF4800090_CR19","doi-asserted-by":"publisher","first-page":"456","DOI":"10.1111\/j.1600-051X.1996.tb00574.x","volume":"23","author":"A Binney","year":"1996","unstructured":"Binney A, Addy M, McKeown S, Everatt L . The choice of controls in toothpaste studies. The effect of a number of commercially available toothpastes compared to water on 4-day plaque regrowth. J Clin Periodontol 1996; 23: 456\u2013459.","journal-title":"J Clin Periodontol"},{"key":"BF4800090_CR20","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1111\/j.1600-051X.1993.tb01761.x","volume":"20","author":"S Jenkins","year":"1993","unstructured":"Jenkins S, Addy M, Newcombe R . The effects of a chlorhexidine toothpaste on the development of plaque, gingivitis and tooth staining. J Clin Periodontol 1993; 20: 59\u201362.","journal-title":"J Clin Periodontol"},{"key":"BF4800090_CR21","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1111\/j.1600-051X.1996.tb00499.x","volume":"23","author":"AJ Smith","year":"1996","unstructured":"Smith A J, Moran J, Dangler L V, Leight R S, Addy M . The efficacy of an anti-gingivitis chewing gum. J Clin Periodontol 1996; 23: 19\u201323.","journal-title":"J Clin Periodontol"},{"key":"BF4800090_CR22","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1902\/jop.1996.67.3.181","volume":"67","author":"G Tellefsen","year":"1996","unstructured":"Tellefsen G, Larsen G, Kaligithi K, Zimmerman G J, Wikesj\u00f6 U M E . Use of chlorhexidine chewing gum significantly reduces dental plaque formation compared to similar xylitol and sorbitol products. J Periodontol 1996; 67: 181\u2013183.","journal-title":"J Periodontol"},{"key":"BF4800090_CR23","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1111\/j.1600-051X.1997.tb00476.x","volume":"24","author":"A Leard","year":"1997","unstructured":"Leard A, Addy M . The propensity of different brands of tea and coffee to cause staining associated with chlorhexidine. J Clin Periodontol 1997; 24: 115\u2013118.","journal-title":"J Clin Periodontol"},{"key":"BF4800090_CR24","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1111\/j.1600-051X.1993.tb00327.x","volume":"20","author":"R Yates","year":"1993","unstructured":"Yates R, Jenkins S, Newcombe R, Wade W, Moran J, Addy M . A 6-months home-usage trial of 1% chlorhexidine toothpaste I) effects on plaque, gingivitis and calculus. J Clin Periodontol 1993; 20: 130\u2013138.","journal-title":"J Clin Periodontol"},{"key":"BF4800090_CR25","first-page":"717","volume":"22","author":"M Addy","year":"1995","unstructured":"Addy M, Wade W . An approach to efficacy screening of mouthrinses: studies on a group of French products (I) Staining and antimicrobial properties in vitro. J Clin Periodontol 1995; 22: 717\u2013722.","journal-title":"J Clin Periodontol"},{"key":"BF4800090_CR26","doi-asserted-by":"publisher","first-page":"723","DOI":"10.1111\/j.1600-051X.1995.tb00833.x","volume":"22","author":"PR Harper","year":"1995","unstructured":"Harper P R, Milsom S, Wade W, Addy M, Moran J, Newcombe R G . An approach to efficacy screening of mouthrinses: studies on a group of French products (II) Inhibition of salivary bacteria and plaque in vivo. J Clin Periodontol 1995; 22: 723\u2013727.","journal-title":"J Clin Periodontol"},{"key":"BF4800090_CR27","doi-asserted-by":"publisher","first-page":"929","DOI":"10.1111\/j.1600-051X.1995.tb01797.x","volume":"22","author":"J Moran","year":"1995","unstructured":"Moran J, Addy M, Newcombe R, Warren P . The comparative effects of phenolic, chlorhexidine and anti-adhesive mouthrinses. J Clin Periodontol 1995; 22: 929\u2013934.","journal-title":"J Clin Periodontol"},{"key":"BF4800090_CR28","doi-asserted-by":"publisher","first-page":"923","DOI":"10.1111\/j.1600-051X.1995.tb01796.x","volume":"22","author":"M Addy","year":"1995","unstructured":"Addy M, Moran J, Newcombe R, Warren P . The comparative tea staining of phenolic, chlorhexidine and anti-adhesive mouthrinses. J Clin Periodontol 1995; 22: 923\u2013928.","journal-title":"J Clin Periodontol"},{"key":"BF4800090_CR29","first-page":"10","volume":"80","author":"L Flotra","year":"1972","unstructured":"Flotra L, Gjermo P, R\u00f6lla G, Waerhaug J . A 4-month study of the effect of chlorhexidine mouthrinses on 50 soldiers. Scand J Dent Res 1972; 80: 10\u201317.","journal-title":"Scand J Dent Res"},{"key":"BF4800090_CR30","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1111\/j.1600-0765.1973.tb02162.x","volume":"12 (suppl.)","author":"L Flotra","year":"1973","unstructured":"Flotra L . Different modes of chlorhexidine application and related side effects. J Periodont Res 1973; 12 (suppl.): 41\u201344.","journal-title":"J Periodont Res"},{"key":"BF4800090_CR31","doi-asserted-by":"publisher","first-page":"595","DOI":"10.1177\/00220345770560060701","volume":"56","author":"RR Lobene","year":"1977","unstructured":"Lobene R R, Lobene S, Soparker P M . The effect of cetylpyridinium chloride mouthrinse on plaque and gingivitis. J Dent Res 1977; 56: 595.","journal-title":"J Dent Res"},{"key":"BF4800090_CR32","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1902\/jop.1986.57.2.108","volume":"57","author":"SG Ciancio","year":"1986","unstructured":"Ciancio S G . Chemotherapeutic agents and periodontal therapy. Their impact on clinical practice. J Periodontol 1986; 57: 108\u2013111.","journal-title":"J Periodontol"},{"key":"BF4800090_CR33","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1111\/j.1834-7819.1975.tb04390.x","volume":"20","author":"JD Holbeche","year":"1975","unstructured":"Holbeche J D, Ruljancich M K, Reade P . A clinical trial of cetylpyridinium chloride mouthwash. Australian Dent J 1975; 20: 397\u2013404.","journal-title":"Australian Dent J"},{"key":"BF4800090_CR34","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1111\/j.1600-051X.1981.tb02040.x","volume":"8","author":"WR Roberts","year":"1981","unstructured":"Roberts W R, Addy M . Comparison of the in vivo and in vitro antibacterial properties of antiseptic mouthrinses containing chlorhexidine, alexidine, cetylpyridinium chloride and hexidine. J Clin Periodontol 1981; 8: 295\u2013310.","journal-title":"J Clin Periodontol"},{"key":"BF4800090_CR35","doi-asserted-by":"publisher","first-page":"562","DOI":"10.1902\/jop.1991.62.9.562","volume":"62","author":"J Moran","year":"1991","unstructured":"Moran J, Addy M . The effects of a cetylpyridinium chloride pre-brushing rinse as an adjunct to oral hygiene and gingival health. J Periodontol 1991; 62: 562\u2013564.","journal-title":"J Periodontol"},{"key":"BF4800090_CR36","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1111\/j.1600-051X.1994.tb00743.x","volume":"21","author":"S Jenkins","year":"1994","unstructured":"Jenkins S, Addy M, Newcombe R . A comparison of cetylpyridinium chloride, triclosan and chlorhexidine mouthrinse formulations for the effect on plaque regrowth. J Clin Periodontol 1994; 21: 441\u2013444.","journal-title":"J Clin Periodontol"},{"key":"BF4800090_CR37","doi-asserted-by":"publisher","first-page":"824","DOI":"10.1111\/j.1600-051X.1995.tb01779.x","volume":"22","author":"BNA Vandekerchhove","year":"1995","unstructured":"Vandekerchhove B N A, Van Steenberge D, Tricio J, Rosenberg D, Encarnacion M . Efficacy on supragingival plaque control of cetylpyridinium chloride in a slow-release dosage form. J Clin Periodontol 1995; 22: 824\u2013829.","journal-title":"J Clin Periodontol"},{"key":"BF4800090_CR38","first-page":"12","volume":"2","author":"RM Gomer","year":"1972","unstructured":"Gomer R M, Hobroyd S V, Fedi P F, Ferrign P D . The effects of oral rinses on the accumulation of dental plaque. J Am Soc Preventive Dent 1972; 2: 12\u201314.","journal-title":"J Am Soc Preventive Dent"},{"key":"BF4800090_CR39","first-page":"31","volume":"4","author":"SS Lusk","year":"1974","unstructured":"Lusk S S, Bowers G M, Tow H D, Watson W J, Moffitt W C . Effects of an oral rinse on experimental gingivitis, plaque formation and formed plaque. J Am Soc Preventive Dent 1974; 4: 31\u201337.","journal-title":"J Am Soc Preventive Dent"},{"key":"BF4800090_CR40","first-page":"18","volume":"83","author":"J Fornell","year":"1975","unstructured":"Fornell J, Sundin Y, Lindhe J . Effect of listerine on dental plaque and gingivitis. Scand J Dent Res 1975; 83: 18\u201325.","journal-title":"Scand J Dent Res"},{"key":"BF4800090_CR41","first-page":"12","volume":"5","author":"IB Lamster","year":"1983","unstructured":"Lamster I B, Alfano M C, Sieger M C, Gordon J M . The effect of listerine antiseptic on reduction of existing plaque and gingivitis. Clin Preventive Dent 1983; 5: 12\u201315.","journal-title":"Clin Preventive Dent"},{"key":"BF4800090_CR42","doi-asserted-by":"publisher","first-page":"697","DOI":"10.1111\/j.1600-051X.1985.tb00941.x","volume":"12","author":"JM Gordon","year":"1985","unstructured":"Gordon J M, Lamster I B, Sieger M C . Efficacy of Listerine antiseptic in inhibiting the development of plaque and gingivitis. J Clin Periodontol 1985; 12: 697\u2013704.","journal-title":"J Clin Periodontol"},{"key":"BF4800090_CR43","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1111\/j.1600-051X.1989.tb01661.x","volume":"16","author":"LG De Paula","year":"1989","unstructured":"De Paula L G, Overholser C D, Meiller T F, Minah G E, Niehaus C . Chemotherapeutic inhibition of supragingival dental plaque and gingivitis development. J Clin Periodontol 1989; 16: 311\u2013315.","journal-title":"J Clin Periodontol"},{"key":"BF4800090_CR44","doi-asserted-by":"publisher","first-page":"636","DOI":"10.1111\/j.1600-051X.1997.tb00241.x","volume":"24","author":"J Moran","year":"1997","unstructured":"Moran J, Addy M, Newcombe R . A 4-day plaque regrowth study comparing an essential oil mouthrinse with a triclosan mouthrinse. J Clin Periodontol 1997; 24: 636\u2013639.","journal-title":"J Clin Periodontol"},{"key":"BF4800090_CR45","doi-asserted-by":"publisher","first-page":"680","DOI":"10.1111\/j.1600-051X.1994.tb00786.x","volume":"21","author":"E Firatli","year":"1994","unstructured":"Firatli E, Unal T, Onan U, Sandalli P . Antioxidative activities of some chemotherapeutics: a possible mechanism of reducing inflammation. J Clin Periodontol 1994; 21: 680\u2013683.","journal-title":"J Clin Periodontol"},{"key":"BF4800090_CR46","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1111\/j.1600-0528.1974.tb00006.x","volume":"2","author":"A Bergenholz","year":"1974","unstructured":"Bergenholz A, Hanstrom L . The plaque inhibiting effect of hexetidine (Oraldene) mouthwash compared to that of chlorhexidine. Community Dent Oral Epidemiol 1974; 2: 70\u201374.","journal-title":"Community Dent Oral Epidemiol"},{"key":"BF4800090_CR47","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1038\/sj.bdj.4807615","volume":"171","author":"B Chadwick","year":"1991","unstructured":"Chadwick B, Addy M, Walker D M . Hexetidine mouthwash in the management of minor aphthous ulceration and as an adjunct to oral hygiene. Br Dent J 1991; 171: 83\u201387.","journal-title":"Br Dent J"},{"key":"BF4800090_CR48","first-page":"49","volume":"95","author":"E Giersten","year":"1987","unstructured":"Giersten E, Svatun B, Saxon A . Plaque inhibition by hexetidine and zinc. Scand J Dent Res 1987; 95: 49\u201354.","journal-title":"Scand J Dent Res"},{"key":"BF4800090_CR49","doi-asserted-by":"publisher","first-page":"730","DOI":"10.1902\/jop.1977.48.11.730","volume":"48","author":"M Addy","year":"1977","unstructured":"Addy M, Griffiths C, Isaac R . The effect of providone iodine on plaque and salivary bacteria - a double blind cross-over trial. J Periodontol 1977; 48: 730\u2013732.","journal-title":"J Periodontol"},{"key":"BF4800090_CR50","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1038\/sj.bdj.4804017","volume":"148","author":"MM Fergerson","year":"1978","unstructured":"Fergerson M M, Geddes D A M, Wray, D . The effect of providone iodine mouthwash on thyroid function and plaque accumulation. Br Dent J 1978; 148: 14\u201316.","journal-title":"Br Dent J"},{"key":"BF4800090_CR51","doi-asserted-by":"publisher","first-page":"578","DOI":"10.1111\/j.1600-051X.1992.tb00686.x","volume":"19","author":"J Moran","year":"1992","unstructured":"Moran J, Addy M, Roberts S . The comparison of a natural product, triclosan and chlorhexidine mouthwashes on 4-day plaque regrowth. J Clin Periodontol 1992; 19: 578\u2013582.","journal-title":"J Clin Periodontol"},{"key":"BF4800090_CR52","doi-asserted-by":"publisher","first-page":"360","DOI":"10.1111\/j.1600-051X.1994.tb00727.x","volume":"21","author":"MJM Schaeken","year":"1994","unstructured":"Schaeken M J M, van der Hoeven J S, Saxen C A, Cummins D . The effect of mouthrinses containing zinc and triclosan on plaque accumulation and development of gingivitis in a 3-week clinical test. J Clin Periodontol 1994; 21: 360\u2013364.","journal-title":"J Clin Periodontol"},{"key":"BF4800090_CR53","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1111\/j.1600-051X.1996.tb00576.x","volume":"23","author":"MJM Schaeken","year":"1996","unstructured":"Schaeken M J M, van der Hoeven J S, Saxen C A, Cummins D . The effect of mouthrinses containing zinc and triclosan on plaque accumulation, development of gingivitis and formation of calculus in a 28 week clinical test. J Clin Periodontol 1996; 23: 465\u2013470.","journal-title":"J Clin Periodontol"},{"key":"BF4800090_CR54","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1111\/j.1600-051X.1996.tb00497.x","volume":"23","author":"P Ramberg","year":"1996","unstructured":"Ramberg P, Furuichi Y, Volpe A R, Gaffar A, Lindhe J . The effects of antimicrobial mouthrinses on de novo plaque formation at sites with healthy and inflamed gingiva. J Clin Periodontol 1996; 23: 7\u201311.","journal-title":"J Clin Periodontol"},{"key":"BF4800090_CR55","first-page":"91","volume":"5","author":"MJ Deasy","year":"1991","unstructured":"Deasy M J, Battista G, Rustogi K N . and Volpe, A.R . Antiplaque efficacy of a triclosan\/copolymer prebrush rinse: a plaque prevention clinical study. Am J Dent 1991; 5: 91\u201394.","journal-title":"Am J Dent"},{"key":"BF4800090_CR56","first-page":"54","volume":"3","author":"RR Lobene","year":"1992","unstructured":"Lobene R R, Singh S S, Garcia L et al. Clinical efficacy of a triclosan\/copolymer pre-brush rinse: a plaque removal study. J Clin Dent 1992; 3: 54\u201358.","journal-title":"J Clin Dent"},{"key":"BF4800090_CR57","doi-asserted-by":"publisher","first-page":"322","DOI":"10.1038\/sj.bdj.4808315","volume":"175","author":"HV Worthington","year":"1993","unstructured":"Worthington H V, Davies R M, Blinkhorn A S et al. A six-month clinical study of the effect of a pre- brush rinse on plaque removal and gingivitis. Br Dent J 1993; 175: 322\u2013326.","journal-title":"Br Dent J"},{"key":"BF4800090_CR58","first-page":"53","volume":"61","author":"F Ayad","year":"1995","unstructured":"Ayad F, Berta R . Effects on plaque and gingivitis of a triclosan \/ copolymer pre-brush rinse : a six month study in Canada. J Can Dent Assoc 1995; 61: 53\u201356.","journal-title":"J Can Dent Assoc"},{"key":"BF4800090_CR59","doi-asserted-by":"crossref","unstructured":"Council on Therapeutics, American Dental Association. Guidelines for acceptance of chemotherapeutic products for the control of plaque and gingivitis. J Am Dent Assoc 1986; 112: 529\u2013532.","DOI":"10.1016\/S0002-8177(86)24021-0"},{"key":"BF4800090_CR60","doi-asserted-by":"publisher","first-page":"529","DOI":"10.1111\/j.1600-0722.1996.tb00137.x","volume":"104","author":"V Kjaerheim","year":"1996","unstructured":"Kjaerheim V, Skaare A, Barkvoll P, R\u00f6lla G . Antiplaque-, antibacterial- and anti-inflammatory properties of triclosan mouthrinses in combination with zinc citrate or polyvinylmethylether maleic acid (PVA-MA) copolymer. Europ J Oral Sci 1996; 104: 529\u2013534.","journal-title":"Europ J Oral Sci"},{"key":"BF4800090_CR61","first-page":"192","volume":"101","author":"SM Waaler","year":"1994","unstructured":"Waaler S M, R\u00f6lla G, Skj\u00f6rland K K, \u00d6gaard B . Effects of oral rinsing with triclosan and sodium lauryl sulfate on dental plaque formation: a pilot study. Scand J Dent Res 1994; 101: 192\u2013195.","journal-title":"Scand J Dent Res"},{"key":"BF4800090_CR62","doi-asserted-by":"publisher","first-page":"717","DOI":"10.1111\/j.1600-051X.1994.tb00792.x","volume":"21","author":"P Barkvoll","year":"1994","unstructured":"Barkvoll P, R\u00f6lla G . Triclosan protects the skin against dermatitis caused by sodium lauryl sulphate exposure. J Clin Periodontol 1994; 21: 717\u2013719.","journal-title":"J Clin Periodontol"},{"key":"BF4800090_CR63","doi-asserted-by":"publisher","first-page":"485","DOI":"10.1111\/j.1600-051X.1995.tb00182.x","volume":"22","author":"P Barkvoll","year":"1995","unstructured":"Barkvoll P, R\u00f6lla G . Triclosan reduces the clinical symptoms of the allergic patch reaction (APR) elicited with 1% nickel sulphate in sensitised patients. J Clin Periodontol 1995; 22: 485\u2013487.","journal-title":"J Clin Periodontol"},{"key":"BF4800090_CR64","doi-asserted-by":"publisher","first-page":"778","DOI":"10.1111\/j.1600-051X.1996.tb00609.x","volume":"23","author":"AB Skaare","year":"1996","unstructured":"Skaare A B, Herlofson B B, Barkvoll P . Mouthrinses containing triclosan reduce the incidence of recurrent aphthous ulcers (RAU). J Clin Periodontol 1996; 23: 778\u2013781.","journal-title":"J Clin Periodontol"},{"key":"BF4800090_CR65","doi-asserted-by":"publisher","first-page":"480","DOI":"10.1111\/j.1600-051X.1995.tb00181.x","volume":"22","author":"A Gaffar","year":"1995","unstructured":"Gaffar A, Scherl D, Affitto J, Colman E J . The effect of triclosan on the mediators of gingival inflammation. J Clin Periodontol 1995; 22: 480\u2013484.","journal-title":"J Clin Periodontol"},{"key":"BF4800090_CR66","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1111\/j.1600-051X.1991.tb01704.x","volume":"18","author":"S Jenkins","year":"1991","unstructured":"Jenkins S, Addy M, Newcombe R . Triclosan and sodium laurylsulphate mouthrinses (II) effects on 4-day plaque regrowth. J Clin Periodontol 1991; 18: 145\u2013148.","journal-title":"J Clin Periodontol"},{"key":"BF4800090_CR67","first-page":"46","volume":"102","author":"SM Waaler","year":"1994","unstructured":"Waaler S M, R\u00f6lla G, Kjaerheim V . Triclosan containing mouthwashes: does the nature of the solvent influence their clinical effect. Scand J of Dent Res 1994; 102: 46\u201349.","journal-title":"Scand J of Dent Res"},{"key":"BF4800090_CR68","first-page":"306","volume":"102","author":"V Kjaerheim","year":"1994","unstructured":"Kjaerheim V, Waaler S M, R\u00f6lla G . Organic solvents and oils as vehicles for triclosan mouthrinses: a clinical study. Scand J Dent Res 1994; 102: 306\u2013308.","journal-title":"Scand J Dent Res"},{"key":"BF4800090_CR69","first-page":"202","volume":"102","author":"V Kjaerheim","year":"1994","unstructured":"Kjaerheim V, Waaler S M, R\u00f6lla G . Significance of choice of solvents for the clinical effect of triclosan-containing mouthrinses. Scand J Dent Res 1994; 102: 202\u2013205.","journal-title":"Scand J Dent Res"},{"key":"BF4800090_CR70","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1111\/j.1600-051X.1997.tb00478.x","volume":"24","author":"AB Skaare","year":"1997","unstructured":"Skaare A B, Kjaerheim V, Barkvoll P, R\u00f6lla G . Does the nature of the solvent affect the anti-inflammatory capacity of triclosan. J Clin Periodontol 1997; 24: 124\u2013128.","journal-title":"J Clin Periodontol"},{"key":"BF4800090_CR71","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1902\/jop.1986.57.9.555","volume":"57","author":"CA Saxen","year":"1986","unstructured":"Saxen C A . The effects of a dentifrice containing zinc citrate and 2.2.4'-hydroxydiphenol. J Periodontol 1986; 57: 555\u2013562.","journal-title":"J Periodontol"},{"key":"BF4800090_CR72","first-page":"211","volume":"2","author":"S Jenkins","year":"1989","unstructured":"Jenkins S, Addy M, Newcombe R . Toothpastes containing 0.3% and 0.5% triclosan. (I) effects on 4-day plaque regrowth. Am J Dent 1989; 2: 211\u2013214.","journal-title":"Am J Dent"},{"key":"BF4800090_CR73","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1111\/j.1600-051X.1987.tb00957.x","volume":"14","author":"CA Saxon","year":"1987","unstructured":"Saxon C A, Lane R M, Van der Ouderaa F . The effects of a toothpaste containing a zinc salt and a non-cationic antimicrobial agent on plaque and gingivitis. J Clin Periodontol 1987; 14: 144\u2013148.","journal-title":"J Clin Periodontol"},{"key":"BF4800090_CR74","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1111\/j.1600-0765.1989.tb00860.x","volume":"24","author":"CA Saxon","year":"1989","unstructured":"Saxon C A, Van der Ouderaa F . The effect of a dentifrice containing zinc citrate and triclosan on the development of gingivitis. J Periodont Res 1989; 24: 75\u201380.","journal-title":"J Periodont Res"},{"key":"BF4800090_CR75","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1111\/j.1600-051X.1987.tb02251.x","volume":"14","author":"B Svantun","year":"1987","unstructured":"Svantun B, Saxon C A, Van der Ouderaa F, R\u00f6lla G . The influence of a dentifrice containing a zinc salt and a non-cationic antimicrobial agent on the maintenance of gingival health. J Clin Periodontol 1987; 14: 457\u2013461.","journal-title":"J Clin Periodontol"},{"key":"BF4800090_CR76","first-page":"242","volume":"97","author":"B Svantun","year":"1989","unstructured":"Svantun B, Saxon C A, R\u00f6lla G, Van der Ouderaa F . One year study of the efficacy of a dentifrice containing a zinc citrate and triclosan to maintain gingival health. Scand J Dent Res 1989; 97: 242\u2013246.","journal-title":"Scand J Dent Res"},{"key":"BF4800090_CR77","first-page":"301","volume":"98","author":"B Svantun","year":"1990","unstructured":"Svantun B, Saxon C A, R\u00f6lla G . Six mouth study of the effect of a dentifrice containing a zinc citrate and triclosan on plaque, gingival health and calculus. Scand J Dent Res 1990; 98: 301\u2013304.","journal-title":"Scand J Dent Res"},{"key":"BF4800090_CR78","doi-asserted-by":"publisher","first-page":"674","DOI":"10.1902\/jop.1990.61.11.674","volume":"61","author":"KW Stephen","year":"1990","unstructured":"Stephen K W, Saxon C A, Jones C L, Richie J A, Morrison T . Control of gingivitis and calculus by a dentifrice containing a zinc salt and and triclosan. J Periodontol 1990; 61: 674\u2013679.","journal-title":"J Periodontol"},{"key":"BF4800090_CR79","first-page":"63","volume":"2","author":"AB Cubells","year":"1991","unstructured":"Cubells A B, Dalmau L B, Petrone M E, Chaknis P, Volpe A R . The effect of a triclosan\/copolymer\/fluoride dentifrice on plaque formation and gingivitis: a six month clinical study. J Clin Dent 1991; 2: 63\u201369.","journal-title":"J Clin Dent"},{"key":"BF4800090_CR80","first-page":"205","volume-title":"Clinical and biological aspects of dentifrices","author":"D Cummins","year":"1992","unstructured":"Cummins D . Mechanisms of actions of clinically proven antiplaque agents. In Embery G, R\u00f6lla G, (eds) Clinical and biological aspects of dentifrices. pp205\u2013228. Oxford: Oxford University Press, 1992."},{"key":"BF4800090_CR81","first-page":"12","volume":"13","author":"MJ Deasy","year":"1992","unstructured":"Deasy M J, Singh S M, Rustogi K N et al. Effect of a dentifrice containing triclosan and a copolymer on plaque formation and gingivitis. Clin Preventive Dent 1992; 13: 12\u201319.","journal-title":"Clin Preventive Dent"},{"key":"BF4800090_CR82","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1111\/j.1600-051X.1989.tb00009.x","volume":"16","author":"S Jenkins","year":"1989","unstructured":"Jenkins S, Addy M, Newcombe R . Studies of the effect of toothpaste rinses on plaque regrowth (II) Triclosan with and without zinc citrate formulations. J Clin Periodontol 1989; 16: 385\u2013387.","journal-title":"J Clin Periodontol"},{"key":"BF4800090_CR83","doi-asserted-by":"publisher","first-page":"334","DOI":"10.1111\/j.1600-051X.1994.tb00722.x","volume":"21","author":"CB Walker","year":"1994","unstructured":"Walker C B, Borden L C, Zambon J J, Bonta C Y, DeVizio W, Volpe A R . The effects of a 0.3% triclosan-containing dentifrice on the microbial composition of supragingival plaque. J Clin Periodontol 1994; 21: 334\u2013341.","journal-title":"J Clin Periodontol"},{"key":"BF4800090_CR84","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1111\/j.1600-051X.1995.tb01772.x","volume":"22","author":"S Renvert","year":"1995","unstructured":"Renvert S, Birkhed D . Comparison between 3 triclosan dentifrices on plaque, gingivitis and salivary microflora. J Clin Periodontol 1995; 22: 63\u201370.","journal-title":"J Clin Periodontol"},{"key":"BF4800090_CR85","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1111\/j.1600-0765.1983.tb00381.x","volume":"14","author":"R Attstrom","year":"1983","unstructured":"Attstrom R, Matsson L, Edwardsson S, Willard L-O, Klinge B . The effect of octapinol on dentogingival plaque and development of gingivitis. (III) Short term studies in humans. J Periodont Res 1983; 14: 445\u2013451.","journal-title":"J Periodont Res"},{"key":"BF4800090_CR86","doi-asserted-by":"publisher","first-page":"290","DOI":"10.1111\/j.1600-0765.1987.tb01587.x","volume":"22","author":"M Brecx","year":"1987","unstructured":"Brecx M, Theilade J, Attstrom R, Glantz P-O . The effect of chlorhexidine and octapinol on early dental plaque formation. A light and electron microscopic study. J Periodontal Res 1987; 22: 290\u2013295.","journal-title":"J Periodontal Res"},{"key":"BF4800090_CR87","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1111\/j.1399-302X.1991.tb00498.x","volume":"6","author":"T Simonsson","year":"1991","unstructured":"Simonsson T, Bondesson H, Rundegren J, Edwardsson S . Effect of delmopinol on in vitro dental plaque formation, bacterial acid production and the number of microorganisms in human saliva. Oral Microbiol and Immunol 1991; 6: 305\u2013309.","journal-title":"Oral Microbiol and Immunol"},{"key":"BF4800090_CR88","doi-asserted-by":"publisher","first-page":"274","DOI":"10.1111\/j.1600-051X.1992.tb00466.x","volume":"19","author":"B Collaert","year":"1992","unstructured":"Collaert B, Attstrom R, DeBrune N, Movert R . The effect of delmopinol rinsing on dental plaque formation and gingivitis healing. J Clin Periodontol 1992; 19: 274\u2013280.","journal-title":"J Clin Periodontol"},{"key":"BF4800090_CR89","doi-asserted-by":"publisher","first-page":"749","DOI":"10.1111\/j.1600-051X.1992.tb02165.x","volume":"19","author":"J Moran","year":"1992","unstructured":"Moran J, Addy M, Wade W G, Maynard J H, Roberts S, \u00c5strom M and Movert R . A comparison of delmopinol and chlorhexidine on plaque regrowth over a 4-day period and salivary bacterial counts. J Clin Periodontol 1992; 19: 749\u2013753.","journal-title":"J Clin Periodontol"},{"key":"BF4800090_CR90","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1080\/08927019109378179","volume":"3","author":"T Simonsson","year":"1991","unstructured":"Simonsson T, Arnebrant T, Peterson L . The delmopinol on the salivary pellicles, the wettable tooth surfaces in vivo and bacterial cell surfaces in vitro. Biofoul 1991; 3: 251\u2013260.","journal-title":"Biofoul"},{"key":"BF4800090_CR91","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1111\/j.1600-051X.1996.tb02079.x","volume":"23","author":"N Claydon","year":"1996","unstructured":"Claydon N, Hunter L, Moran J, Wade W G, Kelty E, Movert R, Addy M . A 6-month home usage of 0.1% and 0.2% delmopinol mouthwashes. (I) Effect on plaque, gingivitis, supragingival calculus and tooth staining. J Clin Periodontol 1996; 23: 220\u2013228.","journal-title":"J Clin Periodontol"},{"key":"BF4800090_CR92","doi-asserted-by":"publisher","first-page":"527","DOI":"10.1111\/j.1600-051X.1995.tb00800.x","volume":"22","author":"AJ Elworthy","year":"1995","unstructured":"Elworthy A J, Edgar R, Moran J, Addy M, Movert R, Kelty E, Wade W G . A 6-month home usage of 0.1% and 0.2% delmopinol mouthwashes (II) Effects on plaque microflora. J Clin Periodontol 1995; 22: 527\u2013532.","journal-title":"J Clin Periodontol"},{"key":"BF4800090_CR93","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1111\/j.1600-051X.1995.tb00801.x","volume":"22","author":"JC Halse","year":"1995","unstructured":"Halse J C, Ainamo J, Etemadzadeh H, \u00c5str\u00f6m M . Plaque formation and gingivitis after mouthrinsing with 0.2% delmopinol hydrochloride, 0.2% chlorhexidine digluconate and placebo for 4 weeks following initial professional tooth cleaning. J Clin Periodontal 1995; 22: 533\u2013539.","journal-title":"J Clin Periodontal"},{"key":"BF4800090_CR94","doi-asserted-by":"publisher","first-page":"486","DOI":"10.1111\/j.1600-051X.1997.tb00216.x","volume":"24","author":"K-Y Zee","year":"1997","unstructured":"Zee K-Y, Rundegen J, Attstr\u00f6m R . Effect of delmopinol hydrochloride mouthrinse on plaque formation and gingivitis in 'rapid' and 'slow' plaque formers. J Clin Periodontol 1997; 24: 486\u2013491.","journal-title":"J Clin Periodontol"},{"key":"BF4800090_CR95","doi-asserted-by":"publisher","first-page":"11S","DOI":"10.14219\/jada.archive.1994.0256","volume":"125","author":"RJ Genco","year":"1994","unstructured":"Genco R J . Pharmaceuticals and periodontal diseases. J Am Dent Assoc 1994; 125: 11S\u201319S.","journal-title":"J Am Dent Assoc"},{"key":"BF4800090_CR96","doi-asserted-by":"publisher","first-page":"1245","DOI":"10.1021\/jm00142a023","volume":"24","author":"RA Coburn","year":"1981","unstructured":"Coburn R A, Batista A J, Evans R T, Genco R J . Potential alicylamide antiplaque agents. In vitro antibacterial activity against Actinomyces viscosus. J Med Chem 1981; 24: 1245\u20131249.","journal-title":"J Med Chem"},{"key":"BF4800090_CR97","doi-asserted-by":"publisher","first-page":"1084","DOI":"10.1111\/j.1600-051X.1996.tb01808.x","volume":"23","author":"N Nabi","year":"1996","unstructured":"Nabi N, Kashuba B, Lucchesi S, Affitto J, Furuichi Y, Gaffar, A . In vitro and in vivo studies of salifluor\/PVM\/MA copolymer\/NaF combination as an antiplaque agent. J Clin Periodontol 1996; 23: 1084\u20131096.","journal-title":"J Clin Periodontol"},{"key":"BF4800090_CR98","doi-asserted-by":"publisher","first-page":"795","DOI":"10.1111\/j.1600-051X.1996.tb00612.x","volume":"23","author":"Y Furuichi","year":"1996","unstructured":"Furuichi Y, Ramberg P, Lindhe J, Nabi N, Gaffar A . Some effects of mouthrinses containing salifluor on de novo plaque formation and developing gingivitis. J Clin Periodontol 1996; 23: 795\u2013802.","journal-title":"J Clin Periodontol"},{"key":"BF4800090_CR99","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1159\/000261447","volume":"26","author":"GS Ingram","year":"1992","unstructured":"Ingram G S, Horay C P, Stead W J . Interaction of zinc with dental mineral. Caries Res 1992; 26: 248\u2013253.","journal-title":"Caries Res"},{"key":"BF4800090_CR100","doi-asserted-by":"publisher","first-page":"213","DOI":"10.3109\/00016358009003491","volume":"38","author":"SM Waaler","year":"1980","unstructured":"Waaler S M, R\u00f6lla G . Plaque inhibition effect of combinations of chlorhexidine with metal ions zinc and tin. Acta Odont Scand 1980; 38: 213\u2013217.","journal-title":"Acta Odont Scand"},{"key":"BF4800090_CR101","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1111\/j.1600-051X.1987.tb00977.x","volume":"14","author":"GL Southard","year":"1987","unstructured":"Southard G L, Parsons L G, Thomas L G, Boulware R T, Woodall I R, Jones B J B . The relationship of sanguinaria extract concentration and zinc ion to plaque and gingivitis. J Clin Periodontol 1987; 14: 315\u2013319.","journal-title":"J Clin Periodontol"},{"key":"BF4800090_CR102","doi-asserted-by":"publisher","first-page":"254","DOI":"10.1038\/sj.bdj.4808727","volume":"178","author":"TH Grenby","year":"1996","unstructured":"Grenby T H . The use of sanguinarine mouthwashes and toothpastes compared with some other antimicrobial agents. Br Dent J 1996; 178: 254\u2013258.","journal-title":"Br Dent J"},{"key":"BF4800090_CR103","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1016\/0889-5406(89)90456-3","volume":"96","author":"JJ Hannah","year":"1989","unstructured":"Hannah J J, Johnson J D, Kuftinee M M . Long-term evaluation of toothpaste and oral rinse containing sanguinaria extract in controlling plaque and gingival inflammation and sulcular bleeding during orthodontic treatment. Am J Orthod Maxillofac Orthopaedics 1989; 96: 199\u2013207.","journal-title":"Am J Orthod Maxillofac Orthopaedics"},{"key":"BF4800090_CR104","doi-asserted-by":"publisher","first-page":"617","DOI":"10.1902\/jop.1991.62.10.617","volume":"62","author":"RA Kopczyk","year":"1991","unstructured":"Kopczyk R A, Abrams H, Brown A T, Matheny J L, Kaplan A L . Clinical and microscopical effects of sanguinaria-containing mouthrinse and dentifrice with and without fluoride during 6 months of use. J Periodontol 1991; 62: 617\u2013622.","journal-title":"J Periodontol"},{"key":"BF4800090_CR105","doi-asserted-by":"publisher","first-page":"488","DOI":"10.1111\/j.1600-051X.1988.tb01020.x","volume":"15","author":"ID Mandel","year":"1988","unstructured":"Mandel I D . Chemotherapeutic agents for controlling plaque and gingivitis. J Clin Periodontol 1988; 15: 488\u2013498.","journal-title":"J Clin Periodontol"},{"key":"BF4800090_CR106","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1111\/j.1600-051X.1988.tb01024.x","volume":"15","author":"CD Overholse","year":"1988","unstructured":"Overholse C D . Longitudinal clinical studies with antimicrobial mouthrinses. J Clin Periodontol 1988; 15: 517\u2013519.","journal-title":"J Clin Periodontol"},{"key":"BF4800090_CR107","doi-asserted-by":"publisher","first-page":"298","DOI":"10.1111\/j.1600-0765.1986.tb01462.x","volume":"21","author":"SE Schonfeld","year":"1986","unstructured":"Schonfeld S E, Farnoush A, Wilson S G . In vivo antiplaque activity of a sanguinarine-containing dentifrice in comparison with conventional toothpastes. J Periodont Res 1986; 21: 298\u2013303.","journal-title":"J Periodont Res"},{"key":"BF4800090_CR108","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1902\/jop.1989.60.2.91","volume":"60","author":"ME Mallatt","year":"1989","unstructured":"Mallatt M E, Beiswanger B B, Drook C A, Stookney G K, Jackson R D, Brickner S L . Clinical effect of a sanguinaria dentifrice on plaque and gingivitis in adults. J Periodontol 1989; 60: 91\u201395.","journal-title":"J Periodontol"},{"key":"BF4800090_CR109","doi-asserted-by":"publisher","first-page":"663","DOI":"10.1128\/AAC.27.4.663","volume":"27","author":"JJ Dzink","year":"1985","unstructured":"Dzink J J, Socransky S S . Comparative in vitro activity of sanguinarine against microbial isolates. Antimicrob Agents Chemotherap 1985; 27: 663\u2013665.","journal-title":"Antimicrob Agents Chemotherap"},{"key":"BF4800090_CR110","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1159\/000261365","volume":"25","author":"AD Eisenberg","year":"1991","unstructured":"Eisenberg A D, Young D A, Fan-Hse J, Spitz L M . Interactions of sanguinarine and zinc on oral streptococci and Actinomyces species. Caries Res 1991; 25: 185\u2013190.","journal-title":"Caries Res"},{"key":"BF4800090_CR111","doi-asserted-by":"publisher","first-page":"612","DOI":"10.1111\/j.1600-051X.1988.tb02260.x","volume":"15","author":"J Moran","year":"1988","unstructured":"Moran J, Addy M, Newcombe R . A clinical trial to assess the efficacy of sanguinarine-zinc mouthrinse (Veadent) compared to a chlorhexidine mouthwash. J Clin Periodontol 1988; 15: 612\u2013616.","journal-title":"J Clin Periodontol"},{"key":"BF4800090_CR112","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1111\/j.1600-051X.1986.tb01419.x","volume":"13","author":"J Wennstrom","year":"1986","unstructured":"Wennstrom J, Lindhe J . The effect of mouthrinses on parameters characterising human periodontal disease. J Clin Periodontol 1986; 13: 86\u201393.","journal-title":"J Clin Periodontol"},{"issue":"suppl.","key":"BF4800090_CR113","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1111\/j.1600-0765.1986.tb01516.x","volume":"21","author":"BE Sigrist","year":"1986","unstructured":"Sigrist B E, Gusberti F A, Brecz M C, Weber H P, Long N P . Efficacy of supervised rinsing with chlorhexidine gluconate in comparison to phenolic and plant alkaloid compounds. J Periodont Res 1986; 21 (suppl.): 60\u201373.","journal-title":"J Periodont Res"},{"key":"BF4800090_CR114","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1902\/jop.1989.60.8.435","volume":"60","author":"E Grossman","year":"1989","unstructured":"Grossman E, Meckel A H, Issacs R L et al. A clinical comparison of antimicrobial mouthrinses: effects of chlorhexidine, phenolics and sanguinarine on dental plaque and gingivitis. J Periodontol 1989; 60: 435\u2013440.","journal-title":"J Periodontol"},{"key":"BF4800090_CR115","doi-asserted-by":"publisher","first-page":"796","DOI":"10.1111\/j.1600-051X.1997.tb01191.x","volume":"24","author":"MC Murray","year":"1997","unstructured":"Murray M C, Worthington H V, Blinkhorn H S . A study to investigate the effect of a propolis-containing mouthrinse on the inhibition of de novo plaque formation. J Clin Periodontol 1997; 24: 796\u2013798.","journal-title":"J Clin Periodontol"},{"key":"BF4800090_CR116","first-page":"440","volume":"16","author":"AB Wade","year":"1966","unstructured":"Wade A B, Blake G C, Mirza K B . Effectiveness of metronidazole in treating the acute phase of ulcerative gingivitis. Dent Practit 1966; 16: 440\u2013443.","journal-title":"Dent Practit"},{"key":"BF4800090_CR117","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1111\/j.1600-051X.1979.tb02190.x","volume":"6","author":"J Wennstrom","year":"1979","unstructured":"Wennstrom J, Lindhe J . The effect of hydrogen peroxide on developing plaque and gingivitis in man. J Clin Periodontol 1979; 6: 115\u2013130.","journal-title":"J Clin Periodontol"},{"key":"BF4800090_CR118","doi-asserted-by":"publisher","first-page":"115","DOI":"10.3109\/15563659208994451","volume":"30","author":"CS Hornfedt","year":"1992","unstructured":"Hornfedt, C.S . A report of acute ethanol poisoning in a child: mouthwash verses cologne perfume and after shave. J Toxicol Clin Toxicol 1992; 30: 115\u2013121.","journal-title":"J Toxicol Clin Toxicol"},{"key":"BF4800090_CR119","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1520\/JFS12936J","volume":"35","author":"K Sperry","year":"1990","unstructured":"Sperry K, Pfalzgraf R . Fatal ethanol intoxication from a household product not intended for ingestion. J Forensic Sci 1990; 35: 1138\u20131142.","journal-title":"J Forensic Sci"},{"key":"BF4800090_CR120","doi-asserted-by":"publisher","first-page":"731","DOI":"10.14219\/jada.archive.1985.0422","volume":"110","author":"A Mashberg","year":"1985","unstructured":"Mashberg A, Barsa P, Grossman M L . A study of the relationship between mouthwash use and oral and pharyngeal cancer. J Am Dent Assoc 1985; 110: 731\u2013734.","journal-title":"J Am Dent Assoc"},{"key":"BF4800090_CR121","first-page":"3044","volume":"51","author":"DM Winn","year":"1991","unstructured":"Winn D M, Blott W G, McLaughlin J K et al. Mouthwash use and oral conditions in the risk of oral and pharyngeal cancer. Cancer Res 1991; 51: 3044\u20133047.","journal-title":"Cancer Res"},{"key":"BF4800090_CR122","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1016\/S0194-5998(95)70114-1","volume":"113","author":"JG Elmore","year":"1995","unstructured":"Elmore J G, Horwitz R I . Oral cancer and mouthwash use: evaluation of epidemiological evidence. Otolaryngeal, Head and Neck Surg 1995; 113: 253\u2013261.","journal-title":"Otolaryngeal, Head and Neck Surg"},{"key":"BF4800090_CR123","doi-asserted-by":"publisher","first-page":"1091","DOI":"10.1093\/oxfordjournals.aje.a008886","volume":"144","author":"S Shapiro","year":"1996","unstructured":"Shapiro S, Castellana J V, Sprafka J M . Alcohol-containing mouthwashes and oropharyngeal cancer: a spurious association due to underascertainment of confounders? Am J Epidemiol 1996; 144: 1091\u20131095.","journal-title":"Am J Epidemiol"},{"key":"BF4800090_CR124","doi-asserted-by":"publisher","first-page":"2955","DOI":"10.1001\/jama.1993.03510240067034","volume":"270","author":"JG Modell","year":"1993","unstructured":"Modell J G, Taylor J, Lee J Y . Breath alcohol values following the use of a mouthwash. J Am Med Assoc 1993; 270: 2955\u20132956.","journal-title":"J Am Med Assoc"},{"key":"BF4800090_CR125","first-page":"60","volume":"5","author":"B Penugonda","year":"1994","unstructured":"Penugonda B, Settembrini L, Scherer W, Wittelman E, Strassler H . Alcohol-containing mouthwashes: effect on composite hardness. J Clin Dent 1994; 5: 60\u201362.","journal-title":"J Clin Dent"},{"key":"BF4800090_CR126","first-page":"249","volume":"22","author":"R Weiner","year":"1997","unstructured":"Weiner R, Millstein P, Hoang E, Marshall D . The effect of alcoholic and non-alcoholic mouthwashes on heat-treated composite resin. Operative Dent 1997; 22: 249\u2013253.","journal-title":"Operative Dent"},{"key":"BF4800090_CR127","doi-asserted-by":"publisher","first-page":"244","DOI":"10.1111\/j.1365-2842.1997.tb00321.x","volume":"24","author":"S Gurgan","year":"1997","unstructured":"Gurgan S, Onen A, Koprula H . In vitro effects of alcohol-containing and alcohol-free mouthrinses on micro-hardness of some dental restorations. J Oral Rehabilitation 1997; 24: 244\u2013246.","journal-title":"J Oral Rehabilitation"},{"key":"BF4800090_CR128","first-page":"14","volume":"20","author":"L Settembrini","year":"1995","unstructured":"Settembrini L, Penugonda B, Scherer W, Strassler H, Wittelman E . Alcohol-containing mouthwashes: effect on composite color. Operative Dent 1995; 20: 14\u201317.","journal-title":"Operative Dent"}],"container-title":["British Dental Journal"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/4800090.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/4800090","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/doifinder\/10.1038\/sj.bdj.4800090","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/www.nature.com\/articles\/4800090.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,11]],"date-time":"2024-03-11T00:38:16Z","timestamp":1710117496000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/4800090"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,3]]},"references-count":128,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1999,3]]}},"alternative-id":["BF4800090"],"URL":"https:\/\/doi.org\/10.1038\/sj.bdj.4800090","relation":{},"ISSN":["0007-0610","1476-5373"],"issn-type":[{"value":"0007-0610","type":"print"},{"value":"1476-5373","type":"electronic"}],"subject":[],"published":{"date-parts":[[1999,3]]}}}