{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T03:57:18Z","timestamp":1777521438786,"version":"3.51.4"},"reference-count":59,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2006,10,24]],"date-time":"2006-10-24T00:00:00Z","timestamp":1161648000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Cancer"],"published-print":{"date-parts":[[2006,11]]},"DOI":"10.1038\/sj.bjc.6603375","type":"journal-article","created":{"date-parts":[[2006,10,24]],"date-time":"2006-10-24T18:48:55Z","timestamp":1161715735000},"page":"1250-1257","source":"Crossref","is-referenced-by-count":31,"title":["Telomerase activity as an adjunct to high-risk human papillomavirus types 16 and 18 and cytology screening in cervical cancer"],"prefix":"10.1038","volume":"95","author":[{"given":"U","family":"Kailash","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C C","family":"Soundararajan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Lakshmy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Arora","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Vivekanandhan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B C","family":"Das","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2006,10,24]]},"reference":[{"key":"BF6603375_CR1","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1016\/j.ejogrb.2004.11.025","volume":"121","author":"R Arora","year":"2005","unstructured":"Arora R, Kumar A, Prusty BK, Kailash U, Das BC (2005) Prevalence of high-risk human papillomavirus (HR-HPV) types 16 and 18 in healthy women with cytologically negative Pap smear. Eur J Obstet Gynecol Reprod Biol 121: 104\u2013109","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"BF6603375_CR2","doi-asserted-by":"publisher","first-page":"1251","DOI":"10.1016\/S0002-9440(10)62552-7","volume":"160","author":"AC Baege","year":"2002","unstructured":"Baege AC, Berger A, Schlegel R, Veldman T, Schlegel R (2002) Cervical epithelial cells transduced with the papillomavirus E6\/E7 oncogenes maintain stable levels of oncoprotein expression but exhibit progressive, major increases in hTERT gene expression and telomerase activity. Am J Pathol 160: 1251\u20131257","journal-title":"Am J Pathol"},{"key":"BF6603375_CR3","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1007\/s11912-002-0079-y","volume":"4","author":"FX Bosch","year":"2002","unstructured":"Bosch FX, de Sanjose S (2002) Human papillomavirus in cervical cancer. Curr Oncol Rep 4: 175\u2013183","journal-title":"Curr Oncol Rep"},{"key":"BF6603375_CR4","doi-asserted-by":"publisher","first-page":"796","DOI":"10.1093\/jnci\/87.11.796","volume":"87","author":"FX Bosch","year":"1995","unstructured":"Bosch FX, Manos MM, Munoz N, Sherman M, Jansen AM, Peto J, Schiffman MH, Moreno V, Kurman R, Shah KV (1995) Prevalence of human papillomavirus in cervical cancer: a worldwide perspective. International biological study on cervical cancer (IBSCC) Study Group. J Natl Cancer Inst 87: 796\u2013802","journal-title":"J Natl Cancer Inst"},{"key":"BF6603375_CR5","doi-asserted-by":"publisher","first-page":"2335","DOI":"10.1101\/gad.9.19.2335","volume":"9","author":"S Cheng","year":"1995","unstructured":"Cheng S, Schmidt-Grimminger DC, Murant T, Broker TR, Chow LT (1995) Differentiation-dependent up-regulation of the human papillomavirus E7 gene reactivates cellular DNA replication in suprabasal differentiated keratinocytes. Genes Dev 9: 2335\u20132349","journal-title":"Genes Dev"},{"key":"BF6603375_CR6","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1038\/sj.bjc.6600688","volume":"88","author":"GM Clifford","year":"2003","unstructured":"Clifford GM, Smith JS, Plummer M, Munoz N, Franceschi S (2003) Human papillomavirus types in invasive cervical cancer worldwide: a meta-analysis. Br J Cancer 88: 63\u201373","journal-title":"Br J Cancer"},{"key":"BF6603375_CR7","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1007\/BF02899679","volume":"62","author":"MT Cornelissen","year":"1992","unstructured":"Cornelissen MT, Bots T, Briet MA, Jebbink MF, Struyk AP, van den Tweel JG, Greer CE, Smits HL, ter Schegget J (1992) Detection of human papillomavirus types by the polymerase chain reaction and the differentiation between high-risk and low-risk cervical lesions. Virchows Arch B Cell Pathol Incl Mol Pathol 62: 167\u2013171","journal-title":"Virchows Arch B Cell Pathol Incl Mol Pathol"},{"key":"BF6603375_CR8","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1016\/0140-6736(92)90431-2","volume":"340","author":"J Cuzick","year":"1992","unstructured":"Cuzick J, Terry G, Ho L, Hollingworth T, Anderson M (1992) HPV in cervical smears. Lancet 340: 112\u2013113","journal-title":"Lancet"},{"key":"BF6603375_CR9","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1038\/bjc.1994.28","volume":"69","author":"J Cuzick","year":"1994","unstructured":"Cuzick J, Terry G, Ho L, Hollingworth T, Anderson M (1994) Type-specific human papillomavirus DNA in abnormal smears as a predictor of high-grade cervical intraepithelial neoplasia. Br J Cancer 69: 167\u2013171","journal-title":"Br J Cancer"},{"key":"BF6603375_CR10","doi-asserted-by":"publisher","first-page":"1271","DOI":"10.1016\/S0140-6736(89)91870-9","volume":"2","author":"BC Das","year":"1989","unstructured":"Das BC, Sehgal A, Murthy NS, Gopalkrishna V, Sharma JK, Das DK, Singh V, Luthra UK (1989) Human papillomavirus and cervical cancer in Indian women. Lancet 2: 1271","journal-title":"Lancet"},{"key":"BF6603375_CR11","doi-asserted-by":"publisher","first-page":"2327","DOI":"10.1099\/0022-1317-73-9-2327","volume":"73","author":"BC Das","year":"1992","unstructured":"Das BC, Sharma JK, Gopalakrishna V, Luthra UK (1992a) Analysis by polymerase chain reaction of the physical state of human papillomavirus type 16 DNA in cervical preneoplastic and neoplastic lesions. J Gen Virol 73: 2327\u20132336","journal-title":"J Gen Virol"},{"key":"BF6603375_CR12","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1002\/jmv.1890360402","volume":"36","author":"BC Das","year":"1992","unstructured":"Das BC, Sharma JK, Gopalkrishna V, Das DK, Singh V, Gissmann L, zur Hausen H, Luthra UK (1992b) A high frequency of human papillomavirus DNA sequences in cervical carcinomas of Indian women as revealed by Southern blot hybridization and polymerase chain reaction. J Med Virol 36: 239\u2013245","journal-title":"J Med Virol"},{"key":"BF6603375_CR13","first-page":"113","volume":"7","author":"P Delvenne","year":"1994","unstructured":"Delvenne P, Fontaine MA, Delvenne C, Nikkels A, Boniver J (1994) Detection of human papillomaviruses in paraffin-embedded biopsies of cervical intraepithelial lesions:analysis by immunohistochemistry, in situ hybridization, and the polymerase chain reaction. Mod Pathol 7: 113\u2013119","journal-title":"Mod Pathol"},{"key":"BF6603375_CR14","doi-asserted-by":"publisher","first-page":"3812","DOI":"10.1073\/pnas.80.12.3812","volume":"80","author":"M Durst","year":"1983","unstructured":"Durst M, Gissmann L, Ikenberg H, zur Hausen H (1983) A papillomavirus DNA from a cervical carcinoma and its prevalence in cancer biopsy samples from different geographic regions. Proc Natl Acad Sci USA 80: 3812\u20133815","journal-title":"Proc Natl Acad Sci USA"},{"issue":"3","key":"BF6603375_CR15","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1097\/00003081-199509000-00018","volume":"38","author":"G Flannelly","year":"1995","unstructured":"Flannelly G, Kitchener H (1995) Every women with an abnormal cervical smear should be referred for treatment: debate. Clin Obstet Gynecol 38(3): 585\u2013591","journal-title":"Clin Obstet Gynecol"},{"key":"BF6603375_CR16","doi-asserted-by":"publisher","first-page":"601","DOI":"10.1038\/sj.bjc.6602348","volume":"92","author":"S Franceschi","year":"2005","unstructured":"Franceschi S, Rajkumar R, Snijders PJ, Arslan A, Mahe C, Plumeer M, Sankarnarayanan R, Cherian J, Meijer CJ, Weiderpass F (2005) Papillomavirus infection in rural women in Southern India. Br J Cancer 92: 601\u2013606","journal-title":"Br J Cancer"},{"key":"BF6603375_CR17","unstructured":"Gopalkrishna V, Hedau S, Kailash U, Das BC (2000) Human papillomavirus type 16 in cancer of the uterine cervix in different geographical regions of India. Conference on Human Papillomavirus Barcelona, Spain Abstract 138"},{"key":"BF6603375_CR18","doi-asserted-by":"crossref","first-page":"3711","DOI":"10.4049\/jimmunol.155.8.3711","volume":"155","author":"K Hiyama","year":"1995","unstructured":"Hiyama K, Hirai Y, Kyoizumi S, Akiyama M, Hiyama E, Piatyszek MA, Shay JW, Ishioka S, Yamakido M (1995) Activation of telomerase in human lymphocytes and hematopoietic progenitor cells. J Immunol 155: 3711\u20133715","journal-title":"J Immunol"},{"key":"BF6603375_CR19","doi-asserted-by":"publisher","first-page":"252","DOI":"10.1093\/jnci\/91.3.252","volume":"91","author":"P Holowaty","year":"1999","unstructured":"Holowaty P, Miller AB, Rohan T, To T (1999) Natural history of dysplasia of the uterine cervix. J Natl Cancer Inst 91: 252\u2013258","journal-title":"J Natl Cancer Inst"},{"key":"BF6603375_CR20","unstructured":"IARC Monographs Working Group (1995) Human Papillomaviruses. Monographs on the Evaluation of Carcinogenic Risks to Humans, Vol. 64, International Agency for Research on Cancer: Lyon, France"},{"key":"BF6603375_CR21","doi-asserted-by":"publisher","first-page":"2027","DOI":"10.1038\/sj.onc.1202142","volume":"17","author":"Y Jian","year":"1998","unstructured":"Jian Y, Schmidt-Grimminger DC, Chien WM, Wu X, Broker TR, Chow LT (1998) Post-transcriptional induction of p21cip1 protein by human papillomavirus E7 inhibits unscheduled DNA synthesis reactivated in differentiated keratinocytes. Oncogene 17: 2027\u20132038","journal-title":"Oncogene"},{"key":"BF6603375_CR22","doi-asserted-by":"publisher","first-page":"2011","DOI":"10.1126\/science.7605428","volume":"266","author":"NW Kim","year":"1995","unstructured":"Kim NW, Piatyszek MA, Prowse KR, Harley CB, West MD, Ho PL, Coviello GM, Wright WE, Weinrich SL, Shay JW (1995) Specific association of human telomerase activity with immortal cells and cancer. Science 266: 2011\u20132015","journal-title":"Science"},{"key":"BF6603375_CR23","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1038\/380079a0","volume":"380","author":"AJ Klingelhutz","year":"1996","unstructured":"Klingelhutz AJ, Foster SA, McDougall JK (1996) Telomerase activation by the E6 gene product of human papillomavirus type 16. Nature 380: 79\u201382","journal-title":"Nature"},{"key":"BF6603375_CR24","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1128\/JVI.61.2.590-593.1987","volume":"61","author":"JW Kreider","year":"1987","unstructured":"Kreider JW, Howett MK, Leure-Dupree AE, Zaino RJ, Weber JA (1987) Laboratory production in vivo of infectious human papillomavirus type 11. J Virol 61: 590\u2013593","journal-title":"J Virol"},{"key":"BF6603375_CR25","doi-asserted-by":"publisher","first-page":"1866","DOI":"10.1001\/jama.1994.03510470070037","volume":"271","author":"RJ Kurman","year":"1994","unstructured":"Kurman RJ, Henson DE, Herbst AL, Noller KL, Schiffman MH (1994) Interim guidelines for management of abnormal cervical cytology. The 1992 National Cancer Institute Workshop. JAMA 271: 1866\u20131869","journal-title":"JAMA"},{"key":"BF6603375_CR26","first-page":"1863","volume":"57","author":"S Kyo","year":"1997","unstructured":"Kyo S, Takakura M, Ishikawa H, Sasagawa T, Satake S, Tateno M, Inoue M (1997) Application of telomerase assay for the screening of cervical lesions. Cancer Res 57: 1863\u20131867","journal-title":"Cancer Res"},{"key":"BF6603375_CR27","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1128\/JVI.58.1.225-229.1986","volume":"58","author":"AT Lorincz","year":"1986","unstructured":"Lorincz AT, Lancaster WD, Temple GF (1986) Cloning and characterization of the DNA of a new human papillomavirus from a woman with dysplasia of the uterine cervix. J Virol 58: 225\u2013229","journal-title":"J Virol"},{"key":"BF6603375_CR28","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1097\/00006250-199203000-00002","volume":"79","author":"AT Lorincz","year":"1992","unstructured":"Lorincz AT, Reid R, Jenson AB, Greenberg MD, Lancaster W, Kurman RJ (1992) Human papillomavirus infection of the cervix: relative risk associations of 15 common anogenital types. Obstet Gynecol 79: 328\u2013337","journal-title":"Obstet Gynecol"},{"key":"BF6603375_CR29","doi-asserted-by":"publisher","first-page":"1101","DOI":"10.1111\/j.1471-0528.1985.tb03019.x","volume":"92","author":"DJ McCance","year":"1985","unstructured":"McCance DJ, Campion MJ, Clarkson PK, Chesters PM, Jenkins D, Singer A (1985) Prevalence of human papillomavirus type 16 DNA sequences in cervical intraepithelial neoplasia and invasive carcinoma of the cervix. Br J Obstet Gynecol 92: 1101","journal-title":"Br J Obstet Gynecol"},{"key":"BF6603375_CR30","first-page":"1323","volume":"62","author":"AK Meeker","year":"1997","unstructured":"Meeker AK, Coffey DS (1997) Telomerase: a promising marker of biological immortality of germ, stem, and cancer cells. A review. Biochemistry (Moscow) 62: 1323\u20131331","journal-title":"Biochemistry (Moscow)"},{"key":"BF6603375_CR31","doi-asserted-by":"publisher","first-page":"518","DOI":"10.1056\/NEJMoa021641","volume":"348","author":"N Munoz","year":"2003","unstructured":"Munoz N, Bosch FX, de Sanjose S, Herrero R, Castellsague X, Shah KV, Snijders PJ, Meijer CJ, International Agency for Research on Cancer Multicenter Cervical Cancer Study Group (2003) Epidemiologic classification of human papillomavirus types associated with cervical cancer. N Engl J Med 348: 518\u2013527","journal-title":"N Engl J Med"},{"key":"BF6603375_CR32","doi-asserted-by":"publisher","first-page":"857","DOI":"10.1016\/S0002-9440(10)65627-1","volume":"153","author":"K Nakano","year":"1998","unstructured":"Nakano K, Watney E, McDougall JK (1998) Telomerase activity and expression of telomerase RNA component and telomerase catalytic subunit gene in cervical cancer. Am J Pathol 153: 857\u2013864","journal-title":"Am J Pathol"},{"key":"BF6603375_CR33","first-page":"1","volume":"47","author":"JD Oriel","year":"1971","unstructured":"Oriel JD (1971) Natural history of genital warts. Br J Vener Dis 47: 1\u201313","journal-title":"Br J Vener Dis"},{"key":"BF6603375_CR34","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1093\/jnci\/88.6.355","volume":"88","author":"TW Park","year":"1996","unstructured":"Park TW, Richart RM, Sun XW, Wright Jr TC (1996) Association between human papillomavirus type and clonal status of cervical squamous intraepithelial lesions. J Natl Cancer Inst 88: 355\u2013358","journal-title":"J Natl Cancer Inst"},{"key":"BF6603375_CR35","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1002\/ijc.1440","volume":"94","author":"DM Parkin","year":"2001","unstructured":"Parkin DM, Bray F, Ferlay J, Pisani P (2001) Estimating the world cancer burden: Globocan 2000. Int J Cancer 94: 153\u2013156","journal-title":"Int J Cancer"},{"key":"BF6603375_CR36","doi-asserted-by":"publisher","first-page":"1469","DOI":"10.1016\/S0140-6736(95)91036-0","volume":"345","author":"AE Raffle","year":"1995","unstructured":"Raffle AE, Alden B, Mackenzie EF (1995) Detection rates for abnormal cervical smears: what are we screening for? Lancet 345: 1469\u20131473","journal-title":"Lancet"},{"key":"BF6603375_CR37","first-page":"F1","volume":"1378","author":"L Rapp","year":"1998","unstructured":"Rapp L, Chen JJ (1998) The papillomavirus E6 proteins. Biochim Biophys Acta 1378: F1\u2013F19","journal-title":"Biochim Biophys Acta"},{"key":"BF6603375_CR38","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1046\/j.1525-1438.2001.011001100.x","volume":"11","author":"VG Reddy","year":"2001","unstructured":"Reddy VG, Khanna N, Jain SK, Das BC, Singh N (2001) Telomerase-A molecular marker for cervical cancer screening. Int J Gynecol Cancer 11: 100\u2013106","journal-title":"Int J Gynecol Cancer"},{"key":"BF6603375_CR39","doi-asserted-by":"publisher","first-page":"212","DOI":"10.1016\/0002-9378(87)90241-9","volume":"156","author":"R Reid","year":"1987","unstructured":"Reid R, Greenberg M, Jenson AB, Husain M, Willett J, Daoud Y, Temple G, Stanhope CR, Sherman AI, Phibbs GD, Lorincz AJ (1987) Sexually transmitted papillomaviral infections. I. The anatomic distribution and pathologic grade of neoplastic lesions associated with different viral types. Am J Obstet Gynecol 156: 212\u2013222","journal-title":"Am J Obstet Gynecol"},{"key":"BF6603375_CR40","doi-asserted-by":"publisher","first-page":"495","DOI":"10.1016\/0092-8674(93)90384-3","volume":"75","author":"M Scheffner","year":"1993","unstructured":"Scheffner M, Huibregtse JM, Vierstra RD, Howley PM (1993) The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53. Cell 75: 495\u2013505","journal-title":"Cell"},{"key":"BF6603375_CR41","doi-asserted-by":"publisher","first-page":"1129","DOI":"10.1016\/0092-8674(90)90409-8","volume":"63","author":"M Scheffner","year":"1990","unstructured":"Scheffner M, Werness BA, Hubregste JM, Levine AJ, Howley PM (1990) The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53. Cell 63: 1129\u20131136","journal-title":"Cell"},{"key":"BF6603375_CR42","doi-asserted-by":"publisher","first-page":"958","DOI":"10.1093\/jnci\/85.12.958","volume":"85","author":"MH Schiffman","year":"1993","unstructured":"Schiffman MH, Bauer HM, Hoover RN, Glass AG, Cadell DM, Rush BB, Scott DR, Sherman ME, Kurman RJ, Wacholder S, Stanton CK, Manos MM (1993) Epidemiologic evidence showing that human papillomavirus infection causes most cervical intraepithelial neoplasia. J Natl Cancer Inst 85: 958\u2013964","journal-title":"J Natl Cancer Inst"},{"key":"BF6603375_CR43","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1093\/jnci\/94.2.102","volume":"94","author":"ME Sherman","year":"2002","unstructured":"Sherman ME, Schiffman M, Cox JT, Atypical Squamous Cells of Undetermined Significance\/Low-Grade Squamous Intraepithelial Lesion Triage Study Group (2002) Effects of age and human papilloma viral load on colposcopy triage: data from the randomized Atypical Squamous Cells of Undetermined Significance\/Low-Grade Squamous Intraepithelial Lesion Triage Study (ALTS). J Natl Cancer Inst 94: 102\u2013107","journal-title":"J Natl Cancer Inst"},{"key":"BF6603375_CR44","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1093\/ajcp\/102.2.182","volume":"102","author":"ME Sherman","year":"1994","unstructured":"Sherman ME, Schiffman MH, Lorincz AT, Manos MM, Scott DR, Kuman RJ, Kiviat NB, Stoler M, Glass AG, Rush BB (1994) Toward objective quality assurance in cervical cytopathology. Correlation of cytopathologic diagnoses with detection of high-risk human papillomavirus types. Am J Clin Pathol 102: 182\u2013187","journal-title":"Am J Clin Pathol"},{"key":"BF6603375_CR45","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1093\/ajcp\/109.2.153","volume":"109","author":"KR Shroyer","year":"1998","unstructured":"Shroyer KR, Thompson LC, Enomoto T, Eskens JL, Shroyer AL, McGregor JA (1998) Telomerase expression in normal epithelium, reactive atypia, squamous dysplasia, and squamous cell carcinoma of the uterine cervix. Am J Clin Pathol 109: 153\u2013162","journal-title":"Am J Clin Pathol"},{"key":"BF6603375_CR46","first-page":"3812","volume":"58","author":"PJ Snijders","year":"1998","unstructured":"Snijders PJ, van Duin M, Walboomers JM, Steenbergen RD, Risse EK, Helmerhorst TJ, Verheijen RH, Meijer CJ (1998) Telomerase activity exclusively in cervical carcinomas and a subset of cervical intraepithelial neoplasia grade III lesions: strong association with elevated messenger RNA levels of its catalytic subunit and high-risk human papillomavirus DNA. Cancer Res 58: 3812\u20133818","journal-title":"Cancer Res"},{"key":"BF6603375_CR47","first-page":"218","volume":"56","author":"HJ Sommerfield","year":"1996","unstructured":"Sommerfield HJ, Meeker AK, Piatyszek MA, Bova GS, Shay JW, Coffey DS (1996) Telomerase activity a prevalent marker of malignant human prostate tissue. Cancer Res 56: 218\u2013222","journal-title":"Cancer Res"},{"key":"BF6603375_CR48","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1006\/viro.2002.1542","volume":"301","author":"DL Sprague","year":"2002","unstructured":"Sprague DL, Phillips SL, Mitchell CJ, Berger KL, Lace M, Turek LP, Klingelhutz AJ (2002) Telomerase activation in cervical keratinocytes containing stably replicating human papillomavirus type 16 episomes. Virology 301: 247\u2013254","journal-title":"Virology"},{"key":"BF6603375_CR49","doi-asserted-by":"publisher","first-page":"1261","DOI":"10.1136\/bmj.293.6557.1261","volume":"293","author":"PG Toorn","year":"1986","unstructured":"Toorn PG, Arrand JR, Wilson LP, Sharp DS (1986) Human papillomavirus infection of the uterine cervix of women without cytological signs of neoplasia. Br Med J 293: 1261\u20131264","journal-title":"Br Med J"},{"key":"BF6603375_CR50","doi-asserted-by":"publisher","first-page":"404","DOI":"10.1002\/ijc.2910480317","volume":"48","author":"AJ Van Den Brule","year":"1991","unstructured":"Van Den Brule AJ, Walboomers JM, Du Maine M, Kenemans P, Meijer CJ (1991) Difference in prevalence of human papillomavirus genotypes in cytomorphologically normal cervical smears is associated with a history of cervical intraepithelial neoplasia. Int J Cancer 48: 404\u2013408","journal-title":"Int J Cancer"},{"key":"BF6603375_CR51","first-page":"516","volume":"92","author":"G Voglino","year":"2000","unstructured":"Voglino G, Poso F, Privitera S, Parisio F, Ghiringhello B, Gordini G, Chiara G, Massobrio M, Fessia L (2000) The role of human papillomavirus in cyto-histological practice: distribution and prevalenceof hig-risk strains (16, 18, 31, 33, and 35) in intraepithelial lesions and neoplasia of the uterine cervix. Pathologica 92: 516\u2013523","journal-title":"Pathologica"},{"key":"BF6603375_CR52","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1126\/science.2157286","volume":"248","author":"BA Werness","year":"1990","unstructured":"Werness BA, Levine AJ, Howley PM (1990) Association of human papillomavirus types 16 and 18 E6 proteins with p53. Science 248: 76\u201379","journal-title":"Science"},{"key":"BF6603375_CR53","doi-asserted-by":"publisher","first-page":"1304","DOI":"10.1053\/hupa.2000.19299","volume":"31","author":"GB Wisman","year":"2000","unstructured":"Wisman GB, Jong SD, Meersma GJ, Helder MN, Hollema H, de Vries EG, Keith WN, van Der Zee AG (2000) Telomerase in (pre)neoplastic cervical disease. Human Pathol 31: 1304\u20131312","journal-title":"Human Pathol"},{"key":"BF6603375_CR54","doi-asserted-by":"publisher","first-page":"658","DOI":"10.1002\/1097-0215(200002)9999:9999<::AID-IJC1099>3.0.CO;2-7","volume":"91","author":"GB Wisman","year":"2001","unstructured":"Wisman GB, Knol AJ, Helder MN, Krans M, DeVries EG, Hollema H, DeJong S, van der Zee AG (2001) Telomerase in relation to clinicipothologic prognostic factors and survival in survival in cervical cancer. Int J Cancer 91: 658\u2013664","journal-title":"Int J Cancer"},{"key":"BF6603375_CR55","doi-asserted-by":"publisher","first-page":"1319","DOI":"10.1002\/(SICI)1097-0142(19980401)82:7<1319::AID-CNCR15>3.0.CO;2-9","volume":"82","author":"K Yashima","year":"1998","unstructured":"Yashima K, Ashfaq R, Nowak J, Von Gruenigen V, Milchgrub S, Rathi A, Albores-Saavedra J, Shay JW, Gazdar AF (1998) Telomerase activity and expression of its RNA component in cervical lesions. Cancer 82: 1319\u20131327","journal-title":"Cancer"},{"key":"BF6603375_CR56","first-page":"667","volume":"76","author":"H Yoshikawa","year":"1985","unstructured":"Yoshikawa H, Matsukura T, Yamamoto E, Kawana T, Mizuno M, Yoshiike K (1985) Occurrence of human papillomavirus types 16 and 18 DNA in cervical carcinomas from Japan: age of patients and histological type of carcinomas. Jpn J Cancer Res 76: 667\u2013671","journal-title":"Jpn J Cancer Res"},{"key":"BF6603375_CR57","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1016\/S0959-8049(98)00303-7","volume":"35","author":"DK Zhang","year":"1999","unstructured":"Zhang DK, Ngan HY, Cheng RY, Cheung AN, Liu SS, Tsao SW (1999) Clinical significance of telomerase activation and telomeric restriction fragment (TRF) in cervical cancer. Eur J Cancer 35: 154\u2013160","journal-title":"Eur J Cancer"},{"key":"BF6603375_CR58","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1006\/gyno.1996.4523","volume":"64","author":"PS Zheng","year":"1997","unstructured":"Zheng PS, Iwasaka T, Yamasaki F, Ouchida M, Yokoyama M, Nakao Y, Fukuda K, Matsuyama T, Sugimori H (1997) Telomerase activity in gynecologic tumors. Gynecol Oncol 64: 171\u2013175","journal-title":"Gynecol Oncol"},{"key":"BF6603375_CR59","doi-asserted-by":"publisher","first-page":"7820","DOI":"10.1038\/sj.onc.1204958","volume":"20","author":"H zur Hausen","year":"2001","unstructured":"zur Hausen H (2001) Oncogenic DNA viruses. Oncogene 20: 7820\u20137823","journal-title":"Oncogene"}],"container-title":["British Journal of Cancer"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/6603375.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/6603375","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/6603375.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T12:23:33Z","timestamp":1684412613000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/6603375"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,10,24]]},"references-count":59,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2006,11]]}},"alternative-id":["BF6603375"],"URL":"https:\/\/doi.org\/10.1038\/sj.bjc.6603375","relation":{},"ISSN":["0007-0920","1532-1827"],"issn-type":[{"value":"0007-0920","type":"print"},{"value":"1532-1827","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,10,24]]}}}