{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T03:58:13Z","timestamp":1778212693228,"version":"3.51.4"},"reference-count":57,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[1999,9,10]],"date-time":"1999-09-10T00:00:00Z","timestamp":936921600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Cancer"],"published-print":{"date-parts":[[1999,10]]},"DOI":"10.1038\/sj.bjc.6690728","type":"journal-article","created":{"date-parts":[[2002,9,5]],"date-time":"2002-09-05T18:09:42Z","timestamp":1031249382000},"page":"542-548","source":"Crossref","is-referenced-by-count":83,"title":["Regular use of analgesics is a risk factor for renal cell carcinoma"],"prefix":"10.1038","volume":"81","author":[{"given":"M","family":"Gago-Dominguez","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J-M","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J E","family":"Castelao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R K","family":"Ross","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M C","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[1999,9,10]]},"reference":[{"key":"BF6690728_CR1","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1016\/S0140-6736(86)90714-2","volume":"1","author":"DH Adams","year":"1986","unstructured":"Adams, DH, Howie, AJ, Michael, J, McConkey, B, Bacon, PA & Adu, D (1986). Non-steroidal anti-inflammatory drugs and renal failure. Lancet 1: 57\u201360.","journal-title":"Lancet"},{"key":"BF6690728_CR2","unstructured":"Antiplatelet Trialists\u2019 Collaboration (1994). Collaborative overview of randomised trials of antiplatelet therapy. I: Prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients. Br Med J 308: 81\u2013106."},{"key":"BF6690728_CR3","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1038\/bjc.1976.17","volume":"33","author":"B Armstrong","year":"1976","unstructured":"Armstrong, B, Garrod, A & Doll, R (1976). A retrospective study of renal cancer with special reference to coffee and animal protein consumption. Br J Cancer 33: 127\u2013136.","journal-title":"Br J Cancer"},{"key":"BF6690728_CR4","first-page":"263","volume":"13","author":"NR Asal","year":"1988","unstructured":"Asal, NR, Geyer, JR, Risser, DR, Lee, ET, Kadamani, S & Cherng, N (1988). Risk factors in renal cell carcinoma. II. Medical history, occupation, multivariate analysis, and conclusions. Cancer Detect Prev 13: 263\u2013279.","journal-title":"Cancer Detect Prev"},{"key":"BF6690728_CR5","doi-asserted-by":"publisher","first-page":"145","DOI":"10.3109\/00365596809135358","volume":"2","author":"U Bengtsson","year":"1968","unstructured":"Bengtsson, U, Angervall, L, Ekman, H & Lehmann, L (1968). Transitional cell tumors of the renal pelvis in analgesic abusers. Scand J Urol Nephrol 2: 145\u2013150.","journal-title":"Scand J Urol Nephrol"},{"key":"BF6690728_CR6","unstructured":"Breslow, NE & Day, NE (1980). Statistical Methods in Cancer Research, Volume I: The Analysis of Case\u2013Control Studies. IARC Scientific publications 32, IARC: Lyon, France."},{"key":"BF6690728_CR7","first-page":"58","volume":"97","author":"BB Brodie","year":"1949","unstructured":"Brodie, BB & Axelrod, J (1949). The fate of acetophenetidin (phenacetin) in man and methods for the estimation of acetophenetidin and its metabolites in biological material. J Pharmacol Exp Ther 97: 58\u201367.","journal-title":"J Pharmacol Exp Ther"},{"key":"BF6690728_CR8","doi-asserted-by":"publisher","first-page":"107","DOI":"10.3109\/00313029109060807","volume":"23","author":"JH Burrell","year":"1991","unstructured":"Burrell, JH, Yong, JL & Macdonald, GJ (1991). Analgesic nephropathy in Fischer 344 rats: comparative effects of chronic treatment with either aspirin or paracetamol. Pathology 23: 107\u2013114.","journal-title":"Pathology"},{"key":"BF6690728_CR9","unstructured":"Consumer Expenditure Study (1985). Product Marketing for Beauty Industry Retailers and Manufacturers 14: 19\u201320."},{"key":"BF6690728_CR10","doi-asserted-by":"publisher","first-page":"358","DOI":"10.1097\/00001648-199607000-00004","volume":"7","author":"LE Derby","year":"1996","unstructured":"Derby, LE & Jick, H (1996). Acetaminophen and renal and bladder cancer. Epidemiology 7: 358\u2013362.","journal-title":"Epidemiology"},{"key":"BF6690728_CR11","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1007\/BF00053164","volume":"1","author":"SS Devesa","year":"1990","unstructured":"Devesa, SS, Silverman, DT, McLaughlin, JK, Brown, CC, Connelly, RR & Fraumeni, JF Jr (1990). Comparison of the descriptive epidemiology of urinary tract cancers. Cancer Causes Control 1: 133\u2013141.","journal-title":"Cancer Causes Control"},{"key":"BF6690728_CR12","doi-asserted-by":"publisher","first-page":"1183","DOI":"10.1016\/0016-5085(94)90246-1","volume":"107","author":"CE Eberhart","year":"1994","unstructured":"Eberhart, CE, Coffey, RJ, Radhika, A, Giardiello, FM, Ferrenbach, S & Dubois, RN (1994). Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas. Gastroenterology 107: 1183\u20131188.","journal-title":"Gastroenterology"},{"key":"BF6690728_CR13","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/0041-008X(91)90325-9","volume":"107","author":"SG Emeigh Hart","year":"1991","unstructured":"Emeigh Hart, SG, Beierschmitt, WP, Bartolone, JB, Wyand, DS, Khairallah, EA & Cohen, SD (1991). Evidence against deacetylation and for cytochrome P450-mediated activation in acetaminophen-induced nephrotoxicity in the CD-1 mouse. Toxicol Appl Pharmacol 107: 1\u201315.","journal-title":"Toxicol Appl Pharmacol"},{"key":"BF6690728_CR14","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1093\/carcin\/4.4.363-a","volume":"4","author":"A Flaks","year":"1983","unstructured":"Flaks, A & Flaks, B (1983). Induction of liver cell tumours in IF mice by paracetamol. Carcinogenesis 4: 363\u2013368.","journal-title":"Carcinogenesis"},{"key":"BF6690728_CR15","doi-asserted-by":"publisher","first-page":"609","DOI":"10.1056\/NEJM199509073331001","volume":"333","author":"E Giovannucci","year":"1995","unstructured":"Giovannucci, E, Egan, KM, Hunter, DJ, Stampfer, MJ, Colditz, GA, Willett, WC & Speizer, FE (1995). Aspirin and the risk of colorectal cancer in women. N Engl J Med 333: 609\u2013614.","journal-title":"N Engl J Med"},{"key":"BF6690728_CR16","doi-asserted-by":"publisher","first-page":"213","DOI":"10.3109\/00313029109063569","volume":"23","author":"GC Gob\u00e9","year":"1991","unstructured":"Gob\u00e9, GC & Axelsen, RA (1991). The role of apoptosis in the development of renal cortical tubular atrophy associated with healed experimental renal papillary necrosis. Pathology 23: 213\u2013223.","journal-title":"Pathology"},{"key":"BF6690728_CR17","doi-asserted-by":"publisher","first-page":"1131","DOI":"10.1126\/science.1957166","volume":"254","author":"BE Henderson","year":"1991","unstructured":"Henderson, BE, Ross, RK & Pike, MC (1991). Toward the primary prevention of cancer. Science 254: 1131\u20131138.","journal-title":"Science"},{"key":"BF6690728_CR18","unstructured":"International Agency for Research on Cancer (1987). Analgesic mixtures containing phenacetin. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans. Updating of IARC Monographs, IARC: Lyon, France Vol 1\u201342: 310\u2013312."},{"key":"BF6690728_CR19","doi-asserted-by":"publisher","first-page":"965","DOI":"10.1002\/ijc.2910440603","volume":"44","author":"OM Jensen","year":"1989","unstructured":"Jensen, OM, Knudsen, JB, Tomasson, H & Sorensen, BL (1989). The Copenhagen case-control study of renal pelvis and ureter cancer: role of analgesics. Int J Cancer 44: 965\u2013968.","journal-title":"Int J Cancer"},{"key":"BF6690728_CR20","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1002\/ijc.2910270416","volume":"27","author":"SL Johansson","year":"1981","unstructured":"Johansson, SL (1981). Carcinogenicity of analgesics: long-term treatment of Sprague-Dawley rats with phenacetin, phenazone, caffeine and paracetamol (acetamidophen). Int J Cancer 27: 521\u2013529.","journal-title":"Int J Cancer"},{"key":"BF6690728_CR21","doi-asserted-by":"publisher","first-page":"252","DOI":"10.1111\/j.1349-7006.1995.tb03048.x","volume":"86","author":"F Kari","year":"1995","unstructured":"Kari, F, Bucher, J, Haseman, J, Eustis, S & Huff, J (1995). Long-term exposure to the anti-inflammatory agent phenylbutazone induces kidney tumors in rats and liver tumors in mice. Jpn J Cancer Res 86: 252\u2013263.","journal-title":"Jpn J Cancer Res"},{"key":"BF6690728_CR22","doi-asserted-by":"publisher","first-page":"1887","DOI":"10.1212\/WNL.43.10.1887","volume":"43","author":"E Kokmen","year":"1993","unstructured":"Kokmen, E, Beard, CM, O\u2019Brien, PC, Offord, KP & Kurland, LT (1993). Is the incidence of dementing illness changing? A 25-year time trend study in Rochester, Minnesota (1960\u20131984). Neurology 43: 1887\u20131892.","journal-title":"Neurology"},{"key":"BF6690728_CR23","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1007\/BF00053150","volume":"4","author":"N Kreiger","year":"1993","unstructured":"Kreiger, N, Marrett, LD, Dodds, L, Hilditch, S & Darlington, GA (1993). Risk factors for renal cell carcinoma: results of a population-based case-control study. Cancer Caus Contr 4: 101\u2013110.","journal-title":"Cancer Caus Contr"},{"key":"BF6690728_CR24","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1016\/0041-008X(85)90171-1","volume":"81","author":"ME Kyle","year":"1985","unstructured":"Kyle, ME & Kocsis, JJ (1985). The effect of age on salicylate-induced nephrotoxicity in male rats. Toxicol Appl Pharmacol 81: 337\u2013347.","journal-title":"Toxicol Appl Pharmacol"},{"key":"BF6690728_CR25","unstructured":"Liu, L, Deapen, D, Bernstein, L & Ross, R (1998). Cancer in Los Angeles County: Incidence and Mortality by Race\/Ethnicity 1988\u20131995. Los Angeles County Cancer Surveillance Program, University of Southern California: Los Angeles, CA."},{"key":"BF6690728_CR26","doi-asserted-by":"publisher","first-page":"2617","DOI":"10.1002\/1097-0142(19820615)49:12<2617::AID-CNCR2820491235>3.0.CO;2-X","volume":"49","author":"M McCredie","year":"1982","unstructured":"McCredie, M, Ford, JM, Taylor, JS & Stewart, JH (1982). Analgesics and cancer of the renal pelvis in New South Wales. Cancer 49: 2617\u20132625.","journal-title":"Cancer"},{"key":"BF6690728_CR27","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1002\/ijc.2910420104","volume":"42","author":"M McCredie","year":"1988","unstructured":"McCredie, M, Ford, JM & Stewart, JH (1988). Risk factors for cancer of the renal parenchyma. Int J Cancer 42: 13\u201316.","journal-title":"Int J Cancer"},{"key":"BF6690728_CR28","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1002\/ijc.2910530212","volume":"53","author":"M McCredie","year":"1993","unstructured":"McCredie, M, Stewart, JH & Day, NE (1993). Different roles for phenacetin and paracetamol in cancer of the kidney and renal pelvis. Int J Cancer 53: 245\u2013249.","journal-title":"Int J Cancer"},{"key":"BF6690728_CR29","doi-asserted-by":"publisher","first-page":"345","DOI":"10.1002\/ijc.2910600312","volume":"60","author":"M McCredie","year":"1995","unstructured":"McCredie, M, Pommer, W, McLaughlin, JK, Stewart, JH, Lindblad, P, Mandel, JS, Mellemgaard, A, Schlehofer, B & Niwa, S (1995). International renal-cell cancer study. II. Analgesics. Int J Cancer 60: 345\u2013349.","journal-title":"Int J Cancer"},{"key":"BF6690728_CR30","doi-asserted-by":"publisher","first-page":"425","DOI":"10.1212\/WNL.47.2.425","volume":"47","author":"PL McGeer","year":"1996","unstructured":"McGeer, PL, Schulzer, M & McGeer, EG (1996). Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer\u2019s disease: a review of 17 epidemiologic studies. Neurology 47: 425\u2013432.","journal-title":"Neurology"},{"key":"BF6690728_CR31","first-page":"217","volume":"69","author":"JK McLaughlin","year":"1985","unstructured":"McLaughlin, JK, Blot, WJ, Mehl, ES & Fraumeni, JF Jr (1985). Relation of analgesic use to renal cancer: population-based findings. Natl Cancer Inst Monogr 69: 217\u2013222.","journal-title":"Natl Cancer Inst Monogr"},{"key":"BF6690728_CR32","doi-asserted-by":"publisher","first-page":"1479","DOI":"10.1056\/NEJM198512053132316","volume":"313","author":"M Maclure","year":"1985","unstructured":"Maclure, M & MacMahon, B (1985). Phenacetin and cancers of the urinary tract. N Engl J Med 313: 1479\u20131480.","journal-title":"N Engl J Med"},{"key":"BF6690728_CR33","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1016\/0041-008X(78)90139-4","volume":"46","author":"RJ McMurtry","year":"1978","unstructured":"McMurtry, RJ, Snodgrass, WR & Mitchell, JR (1978). Renal necrosis, glutathione depletion, and covalent binding after acetaminophen. Toxicol Appl Pharmacol 46: 87\u2013100.","journal-title":"Toxicol Appl Pharmacol"},{"key":"BF6690728_CR34","doi-asserted-by":"publisher","first-page":"463","DOI":"10.1111\/j.1445-5994.1977.tb03366.x","volume":"7","author":"JF Mahony","year":"1977","unstructured":"Mahony, JF, Storey, BG, Ibanez, RC & Stewart, JH (1977). Analgesic abuse, renal parenchymal disease and carcinoma of the kidney or ureter. Aust N Z J Med 7: 463\u2013469.","journal-title":"Aust N Z J Med"},{"key":"BF6690728_CR35","doi-asserted-by":"publisher","first-page":"923","DOI":"10.1093\/ije\/23.5.923","volume":"23","author":"A Mellemgaard","year":"1994","unstructured":"Mellemgaard, A, Niwa, S, Mehl, ES, Engholm, G, McLaughlin, JK & Olsen, JH (1994). Risk factors for renal cell carcinoma in Denmark: role of medication and medical history. Int J Epidemiol 23: 923\u2013930.","journal-title":"Int J Epidemiol"},{"key":"BF6690728_CR36","doi-asserted-by":"publisher","first-page":"549","DOI":"10.1111\/j.1532-5415.1989.tb05688.x","volume":"37","author":"JS Meyer","year":"1989","unstructured":"Meyer, JS, Rogers, RL, McClintic, K, Mortel, KF & Lotfi, J (1989). Randomized clinical trial of daily aspirin therapy in multi-infarct dementia. A pilot study. J Am Geriatr Soc 37: 549\u2013555.","journal-title":"J Am Geriatr Soc"},{"key":"BF6690728_CR37","doi-asserted-by":"publisher","first-page":"518","DOI":"10.1016\/0002-9343(77)90407-7","volume":"62","author":"JR Mitchell","year":"1977","unstructured":"Mitchell, JR, McMurtry, RJ, Statham, CN & Nelson, SD (1977). Molecular basis for several drug-induced nephropathies. Am J Med 62: 518\u2013526.","journal-title":"Am J Med"},{"key":"BF6690728_CR38","doi-asserted-by":"publisher","first-page":"439","DOI":"10.1002\/ijc.2910290413","volume":"29","author":"K Nakanishi","year":"1982","unstructured":"Nakanishi, K, Kurata, Y, Oshima, M, Fukushima, S & Ito, N (1982). Carcinogenicity of phenacetin: long-term feeding study in B6c3fl mice. Int J Cancer 29: 439\u2013444.","journal-title":"Int J Cancer"},{"key":"BF6690728_CR39","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1016\/0002-9343(83)90235-8","volume":"75","author":"RS Nanra","year":"1983","unstructured":"Nanra, RS (1983). Renal effects of antipyretic analgesics. Am J Med 75: 70\u201381.","journal-title":"Am J Med"},{"key":"BF6690728_CR40","unstructured":"National Center for Health, Statistics (1996). Vital Statistics of the United States, 1992: Vol 2, Mortality, Part A. Hyattsville MD: US Dept of Health and Human Services, Public Health Service, CDC: 1996. United States Department of Health and Human Services publication PHS 96-1101."},{"key":"BF6690728_CR41","doi-asserted-by":"publisher","first-page":"1247","DOI":"10.1136\/bmj.299.6710.1247","volume":"299","author":"A Paganini-Hill","year":"1989","unstructured":"Paganini-Hill, A, Chao, A, Ross, RK & Henderson, BE (1989). Aspirin use and chronic diseases: a cohort study of the elderly. Br Med J 299: 1247\u20131250.","journal-title":"Br Med J"},{"key":"BF6690728_CR42","doi-asserted-by":"publisher","first-page":"5","DOI":"10.3322\/canjclin.46.1.5","volume":"46","author":"SL Parker","year":"1996","unstructured":"Parker, SL, Tong, T, Bolden, S & Wingo, PA (1996). Cancer statistics, 1996. CA Cancer J Clin 46: 5\u201327.","journal-title":"CA Cancer J Clin"},{"key":"BF6690728_CR43","doi-asserted-by":"publisher","first-page":"1675","DOI":"10.1056\/NEJM199412223312502","volume":"331","author":"TV Perneger","year":"1994","unstructured":"Perneger, TV, Whelton, PK & Klag, MJ (1994). Risk of kidney failure associated with the use of acetaminophen, aspirin, and nonsteroidal anti-inflammatory drugs. N Engl J Med 331: 1675\u20131679.","journal-title":"N Engl J Med"},{"key":"BF6690728_CR44","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1016\/0009-2797(75)90092-7","volume":"10","author":"DT Plummer","year":"1975","unstructured":"Plummer, DT, Leathwood, PD & Blake, ME (1975). Urinary enzymes and kidney damage by aspirin and phenacetin. Chem Biol Interact 10: 277\u2013284.","journal-title":"Chem Biol Interact"},{"key":"BF6690728_CR45","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1159\/000168002","volume":"9","author":"W Pommer","year":"1989","unstructured":"Pommer, W, Bronder, E, Greiser, E, Helmert, U, Jesdinsky, HJ, Klimpel, A, Borner, K & Molzahn, M (1989). Regular analgesic intake and the risk of end-stage renal failure. Am J Nephrol 9: 403\u2013412.","journal-title":"Am J Nephrol"},{"key":"BF6690728_CR46","doi-asserted-by":"publisher","first-page":"75","DOI":"10.2165\/00003495-198223010-00004","volume":"23","author":"LF Prescott","year":"1982","unstructured":"Prescott, LF (1982). Analgesic nephropathy: a reassessment of the role of phenacetin and other analgesics. Drugs 23: 75\u2013149.","journal-title":"Drugs"},{"key":"BF6690728_CR47","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1023\/A:1008805505154","volume":"9","author":"L Rosenberg","year":"1998","unstructured":"Rosenberg, L, Rao, RS, Palmer, JR, Strom, BL, Zauber, A, Warshauer, ME, Stolley, PD & Shapiro, S (1998). Transitional cell cancer of the urinary tract and renal cell cancer in relation to acetaminophen use (United States). Cancer Caus Contr 9: 83\u201388.","journal-title":"Cancer Caus Contr"},{"key":"BF6690728_CR48","doi-asserted-by":"publisher","first-page":"1152","DOI":"10.1093\/jnci\/89.15.1152","volume":"89","author":"MT Ruffin","year":"1997","unstructured":"Ruffin, MT, Krishnan, K, Rock, CL, Normolle, D, Vaerten, MA, Peters-Golden, M, Crowell, J, Kelloff, G, Boland, CR & Brenner, DE (1997). Suppression of human colorectal mucosal prostaglandins: determining the lowest effective aspirin dose. J Natl Cancer Inst 89: 1152\u20131160.","journal-title":"J Natl Cancer Inst"},{"key":"BF6690728_CR49","doi-asserted-by":"publisher","first-page":"S34","DOI":"10.1016\/S0272-6386(96)90567-3","volume":"28","author":"S Sabatini","year":"1996","unstructured":"Sabatini, S (1996). Pathophysiologic mechanisms in analgesic-induced papillary necrosis. Am J Kidney Dis 28: S34\u2013S38.","journal-title":"Am J Kidney Dis"},{"key":"BF6690728_CR50","doi-asserted-by":"publisher","first-page":"1238","DOI":"10.1056\/NEJM198905113201903","volume":"320","author":"DP Sandler","year":"1989","unstructured":"Sandler, DP, Smith, JC, Weinberg, CR, Buckalew, VM Jr, Dennis, VW, Blythe, WB & Burgess, WP (1989). Analgesic use and chronic renal disease. N Engl J Med 320: 1238\u20131243.","journal-title":"N Engl J Med"},{"key":"BF6690728_CR51","doi-asserted-by":"publisher","first-page":"165","DOI":"10.7326\/0003-4819-115-3-165","volume":"115","author":"DP Sandler","year":"1991","unstructured":"Sandler, DP, Burr, FR & Weinberg, CR (1991). Nonsteroidal anti-inflammatory drugs and the risk for chronic renal disease. Ann Intern Med 115: 165\u2013172.","journal-title":"Ann Intern Med"},{"key":"BF6690728_CR52","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1016\/S0272-6386(12)80155-7","volume":"24","author":"M Segasothy","year":"1994","unstructured":"Segasothy, M, Samad, SA, Zulfigar, A & Bennett, WM (1994). Chronic renal disease and papillary necrosis associated with the long-term use of nonsteroidal anti-inflammatory drugs as the sole or predominant analgesic. Am J Kidney Dis 24: 17\u201324.","journal-title":"Am J Kidney Dis"},{"key":"BF6690728_CR53","doi-asserted-by":"crossref","unstructured":"Steering Committee of the Physicians\u2019 Health Study Research Group (1989). Final report on the aspirin component of the ongoing Physicians\u2019 Health Study. N Engl J Med 321: 129\u2013135.","DOI":"10.1056\/NEJM198907203210301"},{"key":"BF6690728_CR54","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1093\/carcin\/5.4.525","volume":"5","author":"H Tsuda","year":"1984","unstructured":"Tsuda, H, Sakata, T, Masui, T, Imaida, K & Ito, N (1984). Modifying effects of butylated hydroxyanisole, ethoxyquin and acetaminophen on induction of neoplastic lesions in rat liver and kidney initiated by N-ethyl-N-hydroxyethylnitrosamine. Carcinogenesis 5: 525\u2013531.","journal-title":"Carcinogenesis"},{"key":"BF6690728_CR55","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1007\/978-3-642-59839-5_1","volume-title":"Carcinoma of the Kidney and Testis, and Rare Urologic Malignancies","author":"M. C. Yu","year":"1999","unstructured":"Yu, MC, Yuan, J-M & Ross, RK (1999). Epidemiology of renal cell carcinoma. 3\u201313."},{"key":"BF6690728_CR56","doi-asserted-by":"publisher","first-page":"1508","DOI":"10.1038\/bjc.1998.248","volume":"77","author":"J-M Yuan","year":"1998","unstructured":"Yuan, J-M, Castelao, JE, Gago-Dominguez, M, Ross, RK & Yu, MC (1998a). Hypertension, obesity and their medications in relation to renal cell carcinoma. Br J Cancer 77: 1508\u20131513.","journal-title":"Br J Cancer"},{"key":"BF6690728_CR57","first-page":"429","volume":"7","author":"J-M Yuan","year":"1998","unstructured":"Yuan, J-M, Castelao, JE, Gago-Dominguez, M, Yu, MC & Ross, RK (1998b). Tobacco use in relation to renal cell carcinoma. Cancer Epidemiol Biomarkers Prev 7: 429\u2013433.","journal-title":"Cancer Epidemiol Biomarkers Prev"}],"container-title":["British Journal of Cancer"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/6690728.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/6690728","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/6690728.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T12:56:08Z","timestamp":1684414568000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/6690728"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,9,10]]},"references-count":57,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1999,10]]}},"alternative-id":["BF6690728"],"URL":"https:\/\/doi.org\/10.1038\/sj.bjc.6690728","relation":{},"ISSN":["0007-0920","1532-1827"],"issn-type":[{"value":"0007-0920","type":"print"},{"value":"1532-1827","type":"electronic"}],"subject":[],"published":{"date-parts":[[1999,9,10]]}}}