{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T11:48:21Z","timestamp":1761392901432},"reference-count":49,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[1999,9,24]],"date-time":"1999-09-24T00:00:00Z","timestamp":938131200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Cancer"],"published-print":{"date-parts":[[1999,10]]},"DOI":"10.1038\/sj.bjc.6690753","type":"journal-article","created":{"date-parts":[[2002,9,5]],"date-time":"2002-09-05T18:10:15Z","timestamp":1031249415000},"page":"712-720","source":"Crossref","is-referenced-by-count":46,"title":["Metallothionein expression correlates with metastatic and proliferative potential in squamous cell carcinoma of the oesophagus"],"prefix":"10.1038","volume":"81","author":[{"given":"Y","family":"Hishikawa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T","family":"Koji","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D K","family":"Dhar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Kinugasa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Yamaguchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N","family":"Nagasue","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[1999,9,24]]},"reference":[{"key":"BF6690753_CR1","first-page":"199","volume":"4","author":"A Abdel-Mageed","year":"1997","unstructured":"Abdel-Mageed, A & Agrawal, KC (1997) Antisense down-regulation of metallothionein induces growth arrest and apoptosis in human breast carcinoma cells. Cancer Gene Ther 4: 199\u2013207","journal-title":"Cancer Gene Ther"},{"key":"BF6690753_CR2","doi-asserted-by":"publisher","first-page":"775","DOI":"10.1177\/29.6.7252134","volume":"29","author":"JC Adams","year":"1981","unstructured":"Adams, JC (1981) Heavy metal intensification of DAB-based HRP reaction products. J Histochem Cytochem 29: 775","journal-title":"J Histochem Cytochem"},{"key":"BF6690753_CR3","doi-asserted-by":"publisher","first-page":"1954","DOI":"10.1002\/1097-0142(19930315)71:6<1954::AID-CNCR2820710605>3.0.CO;2-#","volume":"71","author":"IF Al-Sheneber","year":"1993","unstructured":"Al-Sheneber, IF, Shibata, HR, Sampalis, J & Jothy, S (1993) Prognostic significance of proliferating cell nuclear antigen expression in colorectal cancer. Cancer 71: 1954\u20131959","journal-title":"Cancer"},{"key":"BF6690753_CR4","doi-asserted-by":"publisher","first-page":"3029","DOI":"10.1002\/1097-0142(19931115)72:10<3029::AID-CNCR2820721027>3.0.CO;2-6","volume":"72","author":"JL Chin","year":"1993","unstructured":"Chin, JL, Banerjee, D, Kadhim, SA, Kontozoglou, TE, Chauvin, PJ & Cherian, MG (1993) Metallothionein in testicular germ cell tumors and drug resistance. Cancer 72: 3029\u20133035","journal-title":"Cancer"},{"key":"BF6690753_CR5","doi-asserted-by":"publisher","first-page":"541","DOI":"10.1016\/0092-8674(88)90076-1","volume":"54","author":"R Chiu","year":"1988","unstructured":"Chiu, R, Boyle, WJ, Meek, J, Smeal, T, Hunter, T & Karin, M (1988) The c-fos protein interacts with jun\/AP-1 to stimulate transcription of AP-1 responsive genes. Cell 54: 541\u2013552","journal-title":"Cell"},{"key":"BF6690753_CR6","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1007\/BF01614773","volume":"423","author":"M Fresno","year":"1993","unstructured":"Fresno, M, Wu, W, Rodriguez, JM & Nadji, M (1993) Localization of metallothionein in breast carcinomas. An immunohistochemical study. Virchows Arch A 423: 215\u2013219","journal-title":"Virchows Arch A"},{"key":"BF6690753_CR7","doi-asserted-by":"publisher","first-page":"968","DOI":"10.1038\/bjc.1995.443","volume":"72","author":"H Goulding","year":"1995","unstructured":"Goulding, H, Jasani, B, Pereira, H, Reid, A, Galea, M, Bell, JA, Elston, CW, Robertson, JF, Blamey, RW, Nicholson, RA, Schmid, KW & Ellis, IO (1995) Metallothionein expression in human breast cancer. Br J Cancer 72: 968\u2013972","journal-title":"Br J Cancer"},{"key":"BF6690753_CR8","doi-asserted-by":"publisher","first-page":"2342","DOI":"10.1016\/S0959-8049(96)00349-8","volume":"32A","author":"A Haga","year":"1996","unstructured":"Haga, A, Nagase, H, Kito, H & Sato, T (1996a) Enhanced invasiveness of tumour cells after host exposure to heavy metals. Eur J Cancer 32A: 2342\u20132347","journal-title":"Eur J Cancer"},{"key":"BF6690753_CR9","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1016\/0304-3835(96)04277-2","volume":"105","author":"A Haga","year":"1996","unstructured":"Haga, A, Nagase, H, Kito, H & Sato, T (1996b) Effect of metallothioneins on transformation of gelatinase A from human fibroblast WI-38 cells. Cancer Lett 105: 175\u2013180","journal-title":"Cancer Lett"},{"key":"BF6690753_CR10","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1002\/path.1711620403","volume":"162","author":"PA Hall","year":"1990","unstructured":"Hall, PA, Levison, DA, Woods, AL, Yu, CCW, Kellock, DB, Watkins, JA, Barnes, DM, Gillett, CE, Camplejohn, R, Dover, R, Waseem, NH & Lane, DP (1990) Proliferating cell nuclear antigen (PCNA) immunolocalization in paraffin sections: an index of cell proliferation with evidence of deregulated expression in some neoplasms. J Pathol 162: 285\u2013294","journal-title":"J Pathol"},{"key":"BF6690753_CR11","doi-asserted-by":"publisher","first-page":"1693","DOI":"10.1002\/1097-0142(19940915)74:6<1693::AID-CNCR2820740609>3.0.CO;2-#","volume":"74","author":"K Hickey","year":"1994","unstructured":"Hickey, K, Grehan, D, Reid, IM, O\u2019Briain, S, Walsh, TN & Hennessy, TPJ (1994) Expression of epidermal growth factor receptor and proliferating cell nuclear antigen predicts response of esophageal squamous cell carcinoma to chemoradiotherapy. Cancer 74: 1693\u20131698","journal-title":"Cancer"},{"key":"BF6690753_CR12","doi-asserted-by":"publisher","first-page":"342","DOI":"10.1159\/000227714","volume":"54","author":"Y Hishikawa","year":"1997","unstructured":"Hishikawa, Y, Abe, S, Kinugasa, S, Yoshimura, H, Monden, N, Igarashi, M, Tachibana, M & Nagasue, N (1997) Overexpression of metallothionein correlates with chemoresistance to cisplatin and prognosis in esophageal cancer. Oncology 54: 342\u2013347","journal-title":"Oncology"},{"key":"BF6690753_CR13","doi-asserted-by":"publisher","first-page":"9958","DOI":"10.1073\/pnas.87.24.9958","volume":"87","author":"MC Hollstein","year":"1990","unstructured":"Hollstein, MC, Metcalf, RA, Welsh, JA, Montesano, R & Harris, CC (1990) Frequent mutation of the p53 gene in human esophageal cancer. Proc Natl Acad Sci USA 87: 9958\u20139961","journal-title":"Proc Natl Acad Sci USA"},{"key":"BF6690753_CR14","doi-asserted-by":"publisher","first-page":"3094","DOI":"10.1002\/j.1460-2075.1994.tb06608.x","volume":"13","author":"E Hu","year":"1994","unstructured":"Hu, E, Mueller, E, Oliviero, S, Papaioannou, VE, Johnson, R & Spiegelman, BM (1994) Targeted disruption of the c-fos gene demonstrates c-fos-dependent and -independent pathways for gene expression stimulated by growth factors or oncogenes. EMBO J 13: 3094\u20133103","journal-title":"EMBO J"},{"key":"BF6690753_CR15","doi-asserted-by":"publisher","first-page":"655","DOI":"10.1136\/jcp.44.8.655","volume":"44","author":"S Jain","year":"1991","unstructured":"Jain, S, Filipe, MI, Hall, PA, Waseem, N, Lane, DP & Levison, DA (1991) Prognostic value of proliferating cell nuclear antigen in gastric carcinoma. J Clin Pathol 44: 655\u2013659","journal-title":"J Clin Pathol"},{"key":"BF6690753_CR16","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1046\/j.1365-2559.1997.2140848.x","volume":"31","author":"B Jasani","year":"1997","unstructured":"Jasani, B & Schmid, KW (1997) Significance of metallothionein overexpression in human tumours. Histopathology 31: 211\u2013214","journal-title":"Histopathology"},{"key":"BF6690753_CR17","doi-asserted-by":"crossref","unstructured":"Jasani, B & Elmes, ME (1991). Immunohistochemical detection of metallothionein. In: Methods in Enzymology Metallobiochemistry, Part B, Metallothionein and Related Molecules, Riordan JF and Vallee BL (eds), pp. 95\u2013107. Academic Press: San Diego","DOI":"10.1016\/0076-6879(91)05091-9"},{"key":"BF6690753_CR18","doi-asserted-by":"publisher","first-page":"797","DOI":"10.1038\/299797a0","volume":"299","author":"M Karin","year":"1982","unstructured":"Karin, M & Richards, RI (1982) Human metallothionein genes \u2013 primary structure of the metallothionein-II gene and a related processed gene. Nature 299: 797\u2013802","journal-title":"Nature"},{"key":"BF6690753_CR19","doi-asserted-by":"publisher","first-page":"5494","DOI":"10.1073\/pnas.81.17.5494","volume":"81","author":"M Karin","year":"1984","unstructured":"Karin, M, Eddy, RL, Henry, WM, Haley, LL, Byers, MG & Shows, TB (1984) Human metallothionein genes are clustered on chromosome 16. Proc Natl Acad Sci USA 81: 5494\u20135498","journal-title":"Proc Natl Acad Sci USA"},{"key":"BF6690753_CR20","first-page":"3237","volume":"51","author":"K Kasahara","year":"1991","unstructured":"Kasahara, K, Fujiwara, Y, Nishio, K, Ohmori, T, Sugimoto, Y, Komiya, K, Matsuda, T & Saijo, N (1991) Metallothionein content correlates with the sensitivity of human small cell lung cancer cell lines to cisplatin. Cancer Res 51: 3237\u20133242","journal-title":"Cancer Res"},{"key":"BF6690753_CR21","doi-asserted-by":"publisher","first-page":"1813","DOI":"10.1126\/science.3175622","volume":"241","author":"SL Kelley","year":"1988","unstructured":"Kelley, SL, Basu, A, Teicher, BA, Hacker, MP, Hamer, DH & Lazo, JS (1988) Overexpression of metallothionein confers resistance to anticancer drugs. Science 241: 1813\u20131815","journal-title":"Science"},{"key":"BF6690753_CR22","doi-asserted-by":"publisher","first-page":"405","DOI":"10.1093\/oxfordjournals.jjco.a023256","volume":"26","author":"S Kinugasa","year":"1996","unstructured":"Kinugasa, S, Tachibana, M, Hishikawa, Y, Abe, S, Yoshimura, H, Monden, M, Dhar, DK & Nagasue, N (1996) Prognostic significance of proliferating cell nuclear antigen (PCNA) in squamous cell carcinoma of the esophagus. Jpn J Clin Oncol 26: 405\u2013410","journal-title":"Jpn J Clin Oncol"},{"key":"BF6690753_CR23","first-page":"1504","volume":"51","author":"Y Kitagawa","year":"1991","unstructured":"Kitagawa, Y, Ueda, M, Ando, N, Shinozawa, Y, Shimizu, N & Abe, O (1991) Significance of int-2\/hst-1 coamplification as a prognostic factor in patients with esophageal squamous carcinoma. Cancer Res 51: 1504\u20131508","journal-title":"Cancer Res"},{"key":"BF6690753_CR24","doi-asserted-by":"publisher","first-page":"382","DOI":"10.1210\/endo.132.1.8419136","volume":"132","author":"T Koji","year":"1993","unstructured":"Koji, T & Brenner, RM (1993) Localization of estrogen receptor messenger ribonucleic acid in rhesus monkey uterus by nonradioactive in situ hybridization with digoxigenin-labeled oligodeoxynucleotides. Endocrinology 132: 382\u2013392","journal-title":"Endocrinology"},{"key":"BF6690753_CR25","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1093\/oxfordjournals.jmicro.a023420","volume":"45","author":"T Koji","year":"1996","unstructured":"Koji, T & Nakane, PK (1996) Recent advances in molecular histochemical techniques: in situ hybridization and southwestern histochemistry. J Electron Microsc 45: 119\u2013127","journal-title":"J Electron Microsc"},{"key":"BF6690753_CR26","first-page":"474","volume":"55","author":"Y Kondo","year":"1995","unstructured":"Kondo, Y, Kuo, S, Watkins, SC & Lazo, JS (1995) Metallothionein localization and cisplatin resistance in human hormone-independent prostatic tumor cell lines. Cancer Res 55: 474\u2013477","journal-title":"Cancer Res"},{"key":"BF6690753_CR27","doi-asserted-by":"publisher","first-page":"709","DOI":"10.1038\/313709a0","volume":"313","author":"MM Le Beau","year":"1985","unstructured":"Le Beau, MM, Diaz, MO, Karin, M & Rowley, JD (1985) Metallothionein gene cluster is split by chromosome 16 rearrangements in myelomocytic leukaemia. Nature 313: 709\u2013711","journal-title":"Nature"},{"key":"BF6690753_CR28","doi-asserted-by":"publisher","first-page":"741","DOI":"10.1016\/0092-8674(87)90612-X","volume":"49","author":"W Lee","year":"1987","unstructured":"Lee, W, Mitchell, P & Tjian, R (1987) Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements. Cell 49: 741\u2013752","journal-title":"Cell"},{"key":"BF6690753_CR29","doi-asserted-by":"publisher","first-page":"48A","DOI":"10.1002\/(SICI)1096-9896(199601)178:1<48::AID-PATH432>3.0.CO;2-Y","volume":"178","author":"K Lim","year":"1996","unstructured":"Lim, K, Evans, A, Adams, M, Fish, R, Dhundee, J, Dallimore, N & Jasani, B (1996) Association of immunohistochemically detectable metallothionein (IDMT) expression with malignant transformation in cervical neoplasia. J Pathol 178: 48A","journal-title":"J Pathol"},{"key":"BF6690753_CR30","doi-asserted-by":"publisher","first-page":"660","DOI":"10.1016\/S0046-8177(84)80292-0","volume":"15","author":"AM Mandard","year":"1984","unstructured":"Mandard, AM, Marnay, J, Gignoux, M, Segol, P, Blanc, L, Ollivier, JM, Borel, B & Mandard, JC (1984) Cancer of the esophagus and associated legions: detailed pathologic study of 100 esophagectomy specimens. Hum Pathol 15: 660\u2013669","journal-title":"Hum Pathol"},{"key":"BF6690753_CR31","doi-asserted-by":"publisher","first-page":"4976","DOI":"10.1073\/pnas.88.11.4976","volume":"88","author":"SJ Meltzer","year":"1991","unstructured":"Meltzer, SJ, Yin, J, Huang, Y, McDaniel, TK, Newkirk, C, Iseri, O, Vogelstein, B & Resau, JH (1991) Reduction to homozygosity involving p53 in esophageal cancers demonstrated by polymerase chain reaction. Proc Natl Acad Sci USA 88: 4976\u20134980","journal-title":"Proc Natl Acad Sci USA"},{"key":"BF6690753_CR32","first-page":"3007","volume":"54","author":"S Miyake","year":"1994","unstructured":"Miyake, S, Nagai, K, Yoshino, K, Oto, M, Endo, M & Yuasa, Y (1994) Point mutations and allelic deletion of tumor suppressor gene DCC in human esophageal squamous cell carcinomas and their relation to metastasis. Cancer Res 54: 3007\u20133010","journal-title":"Cancer Res"},{"key":"BF6690753_CR33","doi-asserted-by":"publisher","first-page":"501","DOI":"10.1016\/0891-5849(90)90128-6","volume":"10","author":"TPJ Mulder","year":"1990","unstructured":"Mulder, TPJ, Verspaget, HW, Janssens, AR, De Bruin, PAF, Griffioen, G & Lamers, CBHW (1990) Neoplasia-related changes of two copper (Cu)\/Zinc (Zn) proteins in the human colon. Free Radical Bio Med 10: 501\u2013506","journal-title":"Free Radical Bio Med"},{"key":"BF6690753_CR34","doi-asserted-by":"publisher","first-page":"579","DOI":"10.1073\/pnas.92.2.579","volume":"92","author":"WW Nagel","year":"1995","unstructured":"Nagel, WW & Vallee, B (1995) Cell cycle regulation of metallothionein in human colonic cancer cells. Proc Natl Acad Sci USA 92: 579\u2013583","journal-title":"Proc Natl Acad Sci USA"},{"key":"BF6690753_CR35","doi-asserted-by":"publisher","first-page":"491","DOI":"10.1007\/BF00197552","volume":"425","author":"D \u00d6fner","year":"1994","unstructured":"\u00d6fner, D, Maier, H, Riedmann, B, Bammer, T, Rumer, A, Winde, G, B\u00f6cker, W, Jasani, B & Schmid, KW (1994) Immunohistochemical metallothionein expression in colorectal adenocarcinoma: correlation with tumour stage and patient survival. Virchows Arch 425: 491\u2013497","journal-title":"Virchows Arch"},{"key":"BF6690753_CR36","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1007\/BF01220802","volume":"122","author":"G Ohshio","year":"1996","unstructured":"Ohshio, G, Imamura, T, Okada, N, Wang, ZH, Yamaki, K, Kyogoku, T, Suwa, H, Yamabe, H & Imamura, M (1996) Immunohistochemical study of metallothionein in pancreatic carcinomas. J Cancer Res Clin 122: 351\u2013355","journal-title":"J Cancer Res Clin"},{"key":"BF6690753_CR37","first-page":"744","volume-title":"Textbook of Surgery","author":"MB Orrigner","year":"1997","unstructured":"Orrigner, MB (1997) Tumors of the esophagus. In: Textbook of Surgery, Sabiston DC Jr (ed), WB Saunders: Philadelphia pp. 744\u2013758"},{"key":"BF6690753_CR38","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1159\/000227546","volume":"53","author":"T Oyama","year":"1996","unstructured":"Oyama, T, Takei, H, Hikino, T, Iino, Y & Nakajima, T (1996) Immunohistochemical expression of metallothionein in invasive breast cancer in relation to proliferative activity, histology and prognosis. Oncology 53: 112\u2013117","journal-title":"Oncology"},{"key":"BF6690753_CR39","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1146\/annurev.cb.06.110190.002543","volume":"6","author":"LJ Ransone","year":"1990","unstructured":"Ransone, LJ & Verma, IM (1990) Nuclear proto-oncogenes fos and jun. Annu Rev Cell Biol 6: 539\u2013557","journal-title":"Annu Rev Cell Biol"},{"key":"BF6690753_CR40","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1007\/BF01607167","volume":"422","author":"KW Schmid","year":"1993","unstructured":"Schmid, KW, Ellis, IO, Gee, JMW, Darke, BM, Lees, WE, Kay, J, Cryer, A, Stark, JM, Hittmair, A, \u00d6fner, D, D\u00fcnser, M, Margreiter, R, Daxenbichler, G, Nicholson, RI, Bier, B, B\u00f6cker, W & Jasani, B (1993) Presence and possible significance of immunocytochemically demonstrable metallothionein over-expression in primary invasive ductal carcinoma of the breast. Virchows Arch A 422: 153\u2013159","journal-title":"Virchows Arch A"},{"key":"BF6690753_CR41","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1007\/BF01046161","volume":"24","author":"EKW Shulte","year":"1992","unstructured":"Shulte, EKW, Lyon, HO & Hoyer, PE (1992) Simultaneous quantification of DNA and RNA in tissue sections. A comparative analysis of the methyl green-pyronin technique with the gallocyanin chromalum and Feulgen procedures using image cytometry. Histochem J 24: 305\u2013310","journal-title":"Histochem J"},{"key":"BF6690753_CR42","first-page":"61","volume-title":"Metallothionein in Biology and Medicine","author":"P Skroch","year":"1991","unstructured":"Skroch, P, Inouye, C & Karin, M (1991) Regulation of human and yeast metallothionein gene transcription by heavy metal ions. In: Metallothionein in Biology and Medicine, Klaassen CD, Suzuki KT (eds), CRC Press: Boca Raton, Florida pp. 61\u201374"},{"key":"BF6690753_CR43","doi-asserted-by":"publisher","first-page":"493","DOI":"10.1001\/archsurg.1990.01410160079018","volume":"25","author":"GD Steele Jr","year":"1990","unstructured":"Steele, GD Jr, Davis, S, Yow, H, Wong, JM, Rivers, EN, Summerhayes, IC, Ravikumar, TS & Chen, LB (1990) Alterations of gene expression in human colorectal cancer. Arch Surg 25: 493\u2013497","journal-title":"Arch Surg"},{"key":"BF6690753_CR44","first-page":"233","volume-title":"The Molecular Basis of Cancer","author":"ML Stracke","year":"1995","unstructured":"Stracke, ML & Liotta, LA (1995) Molecular mechanisms of tumor cell metastasis. In: The Molecular Basis of Cancer, Mendelsohn J, Howley PM, Israel MA, Liotta LA (eds), WB Saunders: Philadelphia pp. 233\u2013247"},{"key":"BF6690753_CR45","doi-asserted-by":"publisher","first-page":"1193","DOI":"10.1002\/hep.1840180527","volume":"18","author":"C Tohyama","year":"1993","unstructured":"Tohyama, C, Suzuki, JS, Hemelraad, J, Nishimura, N & Nishimura, H (1993) Induction of metallothionein and its localization in the nucleus of rat hepatocytes after partial hepatectomy. Hepatology 18: 1193\u20131201","journal-title":"Hepatology"},{"key":"BF6690753_CR46","doi-asserted-by":"publisher","first-page":"321","DOI":"10.1177\/43.3.7532657","volume":"43","author":"A Yoshii","year":"1995","unstructured":"Yoshii, A, Koji, T, Ohsawa, N & Nakane, PK (1995) In situ localization of ribosomal RNAs is a reliable reference for hybridizable RNA in tissue sections. J Histochem Cytochem 43: 321\u2013328","journal-title":"J Histochem Cytochem"},{"key":"BF6690753_CR47","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1111\/j.1365-2559.1993.tb01198.x","volume":"23","author":"B Zelger","year":"1993","unstructured":"Zelger, B, Hittmair, A, Schir, M, \u00d6fner, C, \u00d6fner, D, Fritsch, PO, B\u00f6cker, W, Jasani, B & Schmid, KW (1993) Immunohistochemically demonstrated metallothionein expression in malignant melanoma. Histopathology 23: 257\u2013264","journal-title":"Histopathology"},{"key":"BF6690753_CR48","first-page":"254","volume":"2","author":"B Zelger","year":"1994","unstructured":"Zelger, B, Sidoroff, A, Hopfl, R, \u00d6fner, D, Jasani, B & Schmid, KW (1994) Metallothionein expression in nonmelanoma skin cancer. Appl Immunohistochem 2: 254\u2013260","journal-title":"Appl Immunohistochem"},{"key":"BF6690753_CR49","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1006\/taap.1996.0029","volume":"136","author":"H Zheng","year":"1996","unstructured":"Zheng, H, Liu, J, Choo, KH, Michalska, AE & Klaassen, CD (1996) Metallothionein-I and -II knock-out mice are sensitive to cadmium-induced liver mRNA expression of c-jun and p53. Toxicol Appl Pharm 136: 229\u2013235","journal-title":"Toxicol Appl Pharm"}],"container-title":["British Journal of Cancer"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nature.com\/articles\/6690753.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/6690753","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nature.com\/articles\/6690753.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T12:56:24Z","timestamp":1684414584000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/6690753"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,9,24]]},"references-count":49,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1999,10]]}},"alternative-id":["BF6690753"],"URL":"https:\/\/doi.org\/10.1038\/sj.bjc.6690753","relation":{},"ISSN":["0007-0920","1532-1827"],"issn-type":[{"value":"0007-0920","type":"print"},{"value":"1532-1827","type":"electronic"}],"subject":[],"published":{"date-parts":[[1999,9,24]]}}}