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Neither alone nor associated with iron (II) did SIN\u20101 induce changes in dialysate ascorbic acid or uric acid concentrations.<\/jats:p>\n<\/jats:list-item>\n<jats:list-item>\n<jats:p>Neither co\u2010infusion of a superoxide dismutase mimetic nor uric acid affected SIN\u20101\u2010induced increases in dialysate DA concentration.<\/jats:p>\n<\/jats:list-item>\n<jats:list-item>\n<jats:p>Infusion of the iron chelator deferoxamine (0.2\u2003m<jats:sc>M<\/jats:sc> for 180\u2003min) decreased dialysate DA and attenuated SIN\u20101\u2010induced increases in dialysate DA concentrations.<\/jats:p>\n<\/jats:list-item>\n<jats:list-item>\n<jats:p>These results suggest that iron plays a key role in SIN\u20101\u2010induced release of striatal DA and do not support any role for either peroxynitrite or superoxide anion in SIN\u20101\u2010induced release of striatal DA.<\/jats:p>\n<\/jats:list-item>\n<\/jats:list>\n<\/jats:p><jats:p><jats:italic>British Journal of Pharmacology<\/jats:italic> (2001) 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