{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T06:03:00Z","timestamp":1789711380214,"version":"4.0.1"},"reference-count":26,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2009,1,29]],"date-time":"2009-01-29T00:00:00Z","timestamp":1233187200000},"content-version":"vor","delay-in-days":516,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["bpspubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["British J Pharmacology"],"published-print":{"date-parts":[[2007,9]]},"abstract":"While the expression patterns of cardiac hypertrophy\u2010related genes have been well documented and widely used as markers for hypertrophy, recent research has revealed uncoupling of hypertrophy\u2010related gene profiles and hypertrophic growth. The role of \u03b2\u2010adrenergic signalling in the development of hypertrophy is incompletely understood. The finding of an upregulated expression of hypertrophy\u2010related genes but a suppressed hypertrophy following \u03b2\u2010blockade reveals previously unrecognized sympatho\u2010adrenergic mechanisms of hypertrophic growth.<\/jats:p>British Journal of Pharmacology<\/jats:italic> (2007) 152<\/jats:bold>, 169\u2013171; doi:10.1038\/sj.bjp.0707353<\/jats:ext-link><\/jats:p>","DOI":"10.1038\/sj.bjp.0707353","type":"journal-article","created":{"date-parts":[[2007,6,25]],"date-time":"2007-06-25T12:09:57Z","timestamp":1182773397000},"page":"169-171","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Divergence of hypertrophic growth and fetal gene profile: the influence of \u03b2\u2010blockers"],"prefix":"10.1111","volume":"152","author":[{"given":"X\u2010J","family":"Du","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2009,1,29]]},"reference":[{"key":"e_1_2_3_2_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.231619298"},{"key":"e_1_2_3_3_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0407234102"},{"key":"e_1_2_3_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.106.668863"},{"key":"e_1_2_3_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardiores.2006.06.015"},{"key":"e_1_2_3_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2005.10.016"},{"key":"e_1_2_3_7_1","doi-asserted-by":"publisher","DOI":"10.1161\/hc0102.101365"},{"key":"e_1_2_3_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.0000144801.09557.4c"},{"key":"e_1_2_3_9_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M110722200"},{"key":"e_1_2_3_10_1","doi-asserted-by":"crossref","first-page":"1399","DOI":"10.1172\/JCI17061","article-title":"Pressure\u2010independent cardiac hypertrophy in mice with cardiomyocyte\u2010restricted inactivation of the atrial natriuretic peptide receptor guanylyl cyclase A","volume":"111","author":"Holtwick R","year":"2003","journal-title":"J Clin Invest"},{"key":"e_1_2_3_11_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000160367.99928.87"},{"key":"e_1_2_3_12_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.051625598"},{"key":"e_1_2_3_13_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI11273"},{"key":"e_1_2_3_14_1","doi-asserted-by":"publisher","DOI":"10.1161\/hh1601.095912"},{"key":"e_1_2_3_15_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa012630"},{"key":"e_1_2_3_16_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.275.19.14466"},{"key":"e_1_2_3_17_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI18213"},{"key":"e_1_2_3_18_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI22811"},{"key":"e_1_2_3_19_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.94.26.14730"},{"key":"e_1_2_3_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.hjh.0000203843.41937.2a"},{"key":"e_1_2_3_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjp.0707350"},{"key":"e_1_2_3_22_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00117.2005"},{"key":"e_1_2_3_23_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.104.510594"},{"key":"e_1_2_3_24_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0510138103"},{"key":"e_1_2_3_25_1","doi-asserted-by":"publisher","DOI":"10.1161\/hc3601.095577"},{"key":"e_1_2_3_26_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.0000074905.22908.A6"},{"key":"e_1_2_3_27_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M309661200"}],"container-title":["British Journal of Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1038%2Fsj.bjp.0707353","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1038%2Fsj.bjp.0707353","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/bpspubs.onlinelibrary.wiley.com\/doi\/pdf\/10.1038\/sj.bjp.0707353","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,12]],"date-time":"2023-10-12T15:21:10Z","timestamp":1697124070000},"score":1,"resource":{"primary":{"URL":"https:\/\/bpspubs.onlinelibrary.wiley.com\/doi\/10.1038\/sj.bjp.0707353"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,9]]},"references-count":26,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2007,9]]}},"alternative-id":["10.1038\/sj.bjp.0707353"],"URL":"https:\/\/doi.org\/10.1038\/sj.bjp.0707353","archive":["Portico"],"relation":{},"ISSN":["0007-1188","1476-5381"],"issn-type":[{"value":"0007-1188","type":"print"},{"value":"1476-5381","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,9]]},"assertion":[{"value":"2009-01-29","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}