{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T14:04:38Z","timestamp":1770732278693,"version":"3.49.0"},"reference-count":25,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2000,7,28]],"date-time":"2000-07-28T00:00:00Z","timestamp":964742400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2000,7,28]],"date-time":"2000-07-28T00:00:00Z","timestamp":964742400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Bone Marrow Transplant"],"published-print":{"date-parts":[[2000,8,1]]},"DOI":"10.1038\/sj.bmt.1702504","type":"journal-article","created":{"date-parts":[[2002,9,4]],"date-time":"2002-09-04T15:45:47Z","timestamp":1031154347000},"page":"327-332","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":57,"title":["Prognostic value of hematopoietic chimerism in patients with acute leukemia after allogeneic bone marrow transplantation: a prospective study"],"prefix":"10.1038","volume":"26","author":[{"given":"S-J","family":"Choi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K-H","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J-H","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H-J","family":"Chung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J-S","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S-H","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C-J","family":"Park","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H-S","family":"Chi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W-K","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2000,7,28]]},"reference":[{"key":"BF1702504_CR1","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1182\/blood.V67.3.811.811","volume":"67","author":"RS Hill","year":"1986","unstructured":"Hill RS, Petersen FB, Storb R et al. Mixed hematologic chimerism after allogeneic marrow transplantation for severe aplastic anemia is associated with a higher risk of graft rejection and a lessened incidence of acute graft-versus-host disease Blood 1986 67: 811\u2013816","journal-title":"Blood"},{"key":"BF1702504_CR2","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1182\/blood.V75.1.296.296","volume":"75","author":"DC Roy","year":"1990","unstructured":"Roy DC, Tantravahi R, Murray C et al. Natural history of mixed chimerism after bone marrow transplantation with CD6-depleted allogeneic marrow: a stable equilibrium Blood 1990 75: 296\u2013304","journal-title":"Blood"},{"key":"BF1702504_CR3","first-page":"235","volume":"5","author":"F Frassoni","year":"1990","unstructured":"Frassoni F, Strada P, Sessarego M et al. Mixed chimerism after allogeneic marrow transplantation for leukaemia: correlation with dose of total body irradiation and graft-versus-host disease Bone Marrow Transplant 1990 5: 235\u2013240","journal-title":"Bone Marrow Transplant"},{"key":"BF1702504_CR4","doi-asserted-by":"crossref","first-page":"3103","DOI":"10.1182\/blood.V78.11.3103.3103","volume":"78","author":"MF Bertheas","year":"1991","unstructured":"Bertheas MF, Lafage M, Levy P et al. Influence of mixed chimerism on the results of allogeneic bone marrow transplantation for leukemia Blood 1991 78: 3103\u20133106","journal-title":"Blood"},{"key":"BF1702504_CR5","first-page":"45","volume":"10","author":"BM Bar","year":"1992","unstructured":"Bar BM, Schattenberg A, De Man AJ et al. Influence of the conditioning regimen on erythrocyte chimerism, graft-versus-host disease and relapse after allogeneic transplantation with lymphocyte depleted marrow Bone Marrow Transplant 1992 10: 45\u201352.","journal-title":"Bone Marrow Transplant"},{"key":"BF1702504_CR6","doi-asserted-by":"crossref","first-page":"4385","DOI":"10.1182\/blood.V84.12.4385.bloodjournal84124385","volume":"84","author":"E Roux","year":"1994","unstructured":"Roux E, Helg C, Chapius B et al. Mixed chimerism after bone marrow transplantation and the risk of relapse (letter) Blood 1994 84: 4385\u20134386","journal-title":"Blood"},{"key":"BF1702504_CR7","doi-asserted-by":"crossref","first-page":"3409","DOI":"10.1182\/blood.V83.11.3409.3409","volume":"83","author":"S Mackinnon","year":"1994","unstructured":"Mackinnon S, Barnett L, Heller G, O'Reilly RJ . Minimal residual disease is more common in patients who have mixed T-cell chimerism after bone marrow transplantation for chronic myelogenous leukemia Blood 1994 83: 3409\u20133416","journal-title":"Blood"},{"key":"BF1702504_CR8","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1038\/sj.bmt.1701604","volume":"23","author":"J Serrano","year":"1999","unstructured":"Serrano J, Roman J, Herrera C et al. Increasing mixed haematopoietic chimaerism after BMT with total depletion of CD4+ and partial depletion of CD8+ lymphocytes is associated with a higher incidence of relapse Bone Marrow Transplant 1999 23: 475\u2013482","journal-title":"Bone Marrow Transplant"},{"key":"BF1702504_CR9","doi-asserted-by":"publisher","first-page":"697","DOI":"10.1038\/sj.bmt.1700721","volume":"19","author":"P Bader","year":"1997","unstructured":"Bader P, Holle W, Klingebiel T et al. Mixed hematopoietic chimerism after allogeneic bone marrow transplantation: the impact of quantitative PCR analysis for prediction of relapse and graft rejection in children Bone Marrow Transplant 1997 19: 697\u2013702","journal-title":"Bone Marrow Transplant"},{"key":"BF1702504_CR10","doi-asserted-by":"publisher","first-page":"487","DOI":"10.1038\/sj.bmt.1701119","volume":"21","author":"P Bader","year":"1998","unstructured":"Bader P, Beck J, Frey A et al. Serial and quantitative analysis of mixed hematopoietic chimerism by PCR in patients with acute leukemias allows the prediction of relapse after allogeneic BMT Bone Marrow Transplant 1998 21: 487\u2013495","journal-title":"Bone Marrow Transplant"},{"key":"BF1702504_CR11","first-page":"1161","volume":"18","author":"M Ramirez","year":"1996","unstructured":"Ramirez M, Diaz MA, Garcia-Sanchez F et al. Chimerism after allogeneic hematopoietic cell transplantation in childhood acute lymphoblastic leukemia Bone Marrow Transplant 1996 18: 1161\u20131165","journal-title":"Bone Marrow Transplant"},{"key":"BF1702504_CR12","first-page":"679","volume":"7","author":"M Suttorp","year":"1993","unstructured":"Suttorp M, Schmitz N, Dreger P et al. Monitoring of chimerism after allogeneic bone marrow transplantation with unmanipulated marrow by use of DNA polymorphisms Leukemia 1993 7: 679\u2013687","journal-title":"Leukemia"},{"key":"BF1702504_CR13","doi-asserted-by":"crossref","first-page":"3027","DOI":"10.1182\/blood.V87.7.3027.bloodjournal8773027","volume":"87","author":"K Molloy","year":"1996","unstructured":"Molloy K, Goulden N, Lawler M et al. Patterns of hematopoietic chimerism following bone marrow transplantationfor childhood acute lymphoblastic leukemia from volunteerunrelated donors Blood 1996 87: 3027\u20133031","journal-title":"Blood"},{"key":"BF1702504_CR14","doi-asserted-by":"publisher","first-page":"883","DOI":"10.1038\/sj.bmt.1701445","volume":"22","author":"J-H Lee","year":"1998","unstructured":"Lee J-H, Lee K-H, Kim S et al. Relevance of protein C and S, antithrombin III, von Willebrand factor, and factor VIII for the development of hepatic veno-occlusive disease in patients undergoing allogeneic bone marrow transplantation: a prospective study Bone Marrow Transplant 1998 22: 883\u2013888","journal-title":"Bone Marrow Transplant"},{"key":"BF1702504_CR15","doi-asserted-by":"publisher","first-page":"591","DOI":"10.1038\/sj.bmt.1701955","volume":"24","author":"K-H Lee","year":"1999","unstructured":"Lee K-H, Lee J-H, Choi S-J et al. Randomized comparison of two different schedules of granulocyte colony-stimulating factor administration after allogeneic bone marrow transplantation Bone Marrow Transplant 1999 24: 591\u2013599","journal-title":"Bone Marrow Transplant"},{"key":"BF1702504_CR16","first-page":"746","volume":"49","author":"A Edwards","year":"1991","unstructured":"Edwards A, Civitello A, Hammond HA, Caskey CT . DNA typing and genetic mapping with trimeric and tetrameric tandem repeats Am J Hum Genet 1991 49: 746\u2013756","journal-title":"Am J Hum Genet"},{"key":"BF1702504_CR17","first-page":"175","volume":"55","author":"HA Hammond","year":"1994","unstructured":"Hammond HA, Jin L, Zhong Y et al. Evaluation of 13 short tandem repeat loci for use in personal identification applications Am J Hum Genet 1994 55: 175\u2013189","journal-title":"Am J Hum Genet"},{"key":"BF1702504_CR18","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1093\/hmg\/1.2.137","volume":"1","author":"R Anker","year":"1992","unstructured":"Anker R, Steinbrueck T, Donis-Keller H . Tetranucleotide repeat polymorphism at the human thyroid peroxidase (hTPO) locus Hum Mol Genet 1992 1: 137","journal-title":"Hum Mol Genet"},{"key":"BF1702504_CR19","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1016\/0888-7543(92)90371-X","volume":"12","author":"A Edwards","year":"1992","unstructured":"Edwards A, Hammond HA, Jin L et al. Genetic variation at five trimeric and tetrameric tandem repeat loci in four human population groups Genomics 1992 12: 241\u2013253","journal-title":"Genomics"},{"key":"BF1702504_CR20","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1093\/hmg\/1.4.287","volume":"1","author":"C Kimpton","year":"1992","unstructured":"Kimpton C, Walton A, Gill P et al. A further tetranucleotide repeat polymorphism in the vWF gene Hum Mol Genet 1992 1: 287","journal-title":"Hum Mol Genet"},{"key":"BF1702504_CR21","first-page":"1167","volume":"20","author":"DY Nishimura","year":"1992","unstructured":"Nishimura DY, Murray JC . A tetranucleotide repeat for the F13B locus Nucleic Acids Res 1992 20: 1167","journal-title":"Nucleic Acids Res"},{"key":"BF1702504_CR22","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1093\/nar\/20.2.211","volume":"20","author":"C Schlotterer","year":"1992","unstructured":"Schlotterer C, Tautz D . Slippage synthesis of simple sequence DNA Nucleic Acids Res 1992 20: 211\u2013215","journal-title":"Nucleic Acids Res"},{"key":"BF1702504_CR23","first-page":"636","volume":"15","author":"KM Sullivan","year":"1993","unstructured":"Sullivan KM, Mannucci A, Kimpton CP, Gill P . A rapid and quantitative DNA sex test: fluorescence-based PCR analysis of X-Y homologous gene amelogenin Biotechniques 1993 15: 636\u2013641","journal-title":"Biotechniques"},{"key":"BF1702504_CR24","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1016\/0003-2697(91)90120-I","volume":"196","author":"BJ Bassam","year":"1991","unstructured":"Bassam BJ, Caetano-Anolles G, Gresshoff PM . Fast and sensitive silver staining of DNA in polyacrylamide gels Anal Biochem 1991 196: 80\u201383","journal-title":"Anal Biochem"},{"key":"BF1702504_CR25","doi-asserted-by":"publisher","first-page":"1055","DOI":"10.1038\/sj.bmt.1701779","volume":"23","author":"C Thiede","year":"1999","unstructured":"Thiede C, Florek M, Bornhauser M et al. Rapid quantification of mixed chimerism using multiplex amplification of short tandem repeat markers and fluorescence detection Bone Marrow Transplant 1999 23: 1055\u20131060","journal-title":"Bone Marrow Transplant"}],"container-title":["Bone Marrow Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/1702504.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/1702504","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/1702504.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,23]],"date-time":"2022-03-23T21:44:54Z","timestamp":1648071894000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/1702504"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,7,28]]},"references-count":25,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2000,8,1]]}},"alternative-id":["BF1702504"],"URL":"https:\/\/doi.org\/10.1038\/sj.bmt.1702504","relation":{},"ISSN":["0268-3369","1476-5365"],"issn-type":[{"value":"0268-3369","type":"print"},{"value":"1476-5365","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,7,28]]},"assertion":[{"value":"30 December 1999","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 April 2000","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 July 2000","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}