{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T16:47:48Z","timestamp":1761842868174},"reference-count":25,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2001,3,1]],"date-time":"2001-03-01T00:00:00Z","timestamp":983404800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2001,3,1]],"date-time":"2001-03-01T00:00:00Z","timestamp":983404800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Bone Marrow Transplant"],"published-print":{"date-parts":[[2001,3,1]]},"DOI":"10.1038\/sj.bmt.1702849","type":"journal-article","created":{"date-parts":[[2002,9,4]],"date-time":"2002-09-04T15:50:37Z","timestamp":1031154637000},"page":"641-646","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":91,"title":["Thrombotic thrombocytopenic purpura-like syndromes following bone marrow transplantation: an analysis of associated conditions and clinical outcomes"],"prefix":"10.1038","volume":"27","author":[{"given":"V","family":"Roy","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MA","family":"Rizvi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"SK","family":"Vesely","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JN","family":"George","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2001,4,23]]},"reference":[{"key":"BF1702849_CR1","doi-asserted-by":"publisher","first-page":"453","DOI":"10.7326\/0003-4819-131-6-199909210-00011","volume":"131","author":"WF Clark","year":"1999","unstructured":"Clark WF, Rock GA, Buskard N et al. Therapeutic plasma exchange: an update from the Canadian Apheresis Group Ann Int Med 1999 131: 453\u2013462","journal-title":"Ann Int Med"},{"key":"BF1702849_CR2","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1097\/00005792-196603000-00003","volume":"45","author":"EL Amorosi","year":"1966","unstructured":"Amorosi EL, Ultmann JE . Thrombotic thrombocytopenic purpura: report of 16 cases and review of the literature Medicine 1966 45: 139\u2013159","journal-title":"Medicine"},{"key":"BF1702849_CR3","unstructured":"George JN, El-Harake MA . Thrombocytopenia due to enhanced platelet destruction by nonimmunologic mechanisms. In: Beutler E, Lichtman MA, Coller BS, Kipps TJ (eds).Williams Hematology McGraw-Hill: New York 1995; pp 1290\u20131314"},{"key":"BF1702849_CR4","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1056\/NEJM199108083250604","volume":"325","author":"GA Rock","year":"1991","unstructured":"Rock GA, Shumak KH, Buskard NA et al. Comparison of plasma exchange with plasma infusion in the treatment of thrombotic thrombocytopenic purpura New Engl J Med 1991 325: 393\u2013397","journal-title":"New Engl J Med"},{"key":"BF1702849_CR5","doi-asserted-by":"crossref","first-page":"1890","DOI":"10.1182\/blood.V80.8.1890.bloodjournal8081890","volume":"80","author":"CE Thompson","year":"1992","unstructured":"Thompson CE, Damon LE, Ries CA, Linker CA . Thrombotic microangiopathies in the 1980s: clinical features, response to treatment, and the impact of the human immunodeficiency virus epidemic Blood 1992 80: 1890\u20131895","journal-title":"Blood"},{"key":"BF1702849_CR6","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1182\/blood.V96.4.1223","volume":"96","author":"JN George","year":"2000","unstructured":"George JN . How I treat patients with thrombotic thrombocytopenic purpura-hemolytic uremic syndrome Blood 2000 96: 1223\u20131229","journal-title":"Blood"},{"key":"BF1702849_CR7","first-page":"495","volume":"14","author":"AR Pettitt","year":"1994","unstructured":"Pettitt AR, Clark RE . Thrombotic microangiopathy following bone marrow transplantation Bone Marrow Transplant 1994 14: 495\u2013504","journal-title":"Bone Marrow Transplant"},{"key":"BF1702849_CR8","first-page":"247","volume":"15","author":"ZR Zeigler","year":"1995","unstructured":"Zeigler ZR, Shadduck RK, Nemunaitis J et al. Bone marrow transplant-associated thrombotic microangiopathy: a case series Bone Marrow Transplant 1995 15: 247\u2013253","journal-title":"Bone Marrow Transplant"},{"key":"BF1702849_CR9","first-page":"126","volume":"34","author":"JR Schriber","year":"1997","unstructured":"Schriber JR, Herzig GP . Transplantation-associated thrombotic thrombocytopenic purpura and hemolytic uremic syndrome Semin Hematol 1997 34: 126\u2013133","journal-title":"Semin Hematol"},{"key":"BF1702849_CR10","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1038\/sj.bmt.1701830","volume":"24","author":"P Iacopino","year":"1999","unstructured":"Iacopino P, Pucci G, Arcese W et al. Gruppo Italiano Trapianto Midollo Osseo (GITMO). Severe thrombotic microangiopathy: an infrequent complication of bone marrow transplantation Bone Marrow Transplant 1999 24: 47\u201351","journal-title":"Bone Marrow Transplant"},{"key":"BF1702849_CR11","doi-asserted-by":"publisher","first-page":"705","DOI":"10.1038\/sj.bmt.1701151","volume":"21","author":"H Kanamori","year":"1998","unstructured":"Kanamori H, Maruta A, Sasaki S et al. Diagnostic value of hemostatic parameters in bone marrow transplantation-associated thrombotic microangiopathy Bone Marrow Transplant 1998 21: 705\u2013709","journal-title":"Bone Marrow Transplant"},{"key":"BF1702849_CR12","doi-asserted-by":"publisher","first-page":"398","DOI":"10.1056\/NEJM199108083250605","volume":"325","author":"WR Bell","year":"1991","unstructured":"Bell WR, Braine HG, Ness PM, Kickler TS . Improved survival in thrombotic thrombocytopenic purpura-hemolytic uremic syndrome New Engl J Med 1991 325: 398\u2013403","journal-title":"New Engl J Med"},{"key":"BF1702849_CR13","first-page":"pp 1003","volume-title":"Heptinstall's Pathology of the Kidney","author":"Z Laszik","year":"1998","unstructured":"Laszik Z, Silva F . Hemolytic-uremic syndrome, thrombotic thrombocytopenia purpura, and systemic sclerosis (systemic scleroderma). In: Jennett JC, Olson JL, Schwartz MM, Silva FG (eds) Heptinstall's Pathology of the Kidney Lippincott-Raven: Philadelphia 1998 pp 1003\u20131057"},{"key":"BF1702849_CR14","doi-asserted-by":"publisher","first-page":"919","DOI":"10.1038\/sj.bmt.1702003","volume":"24","author":"Y Matsuda","year":"1999","unstructured":"Matsuda Y, Hara J, Miyoshi H et al. Thrombotic microangiopathy associated with reactivation of human herpesvirus-6 following high-dose chemotherapy with autologous marrow transplantation in young children Bone Marrow Transplant 1999 24: 919\u2013923","journal-title":"Bone Marrow Transplant"},{"key":"BF1702849_CR15","doi-asserted-by":"crossref","first-page":"1224","DOI":"10.1182\/blood.V89.4.1224","volume":"89","author":"D Mitra","year":"1997","unstructured":"Mitra D, Jaffe EA, Weksler B et al. Thrombotic thrombocytopenic purpura and sporadic hemolyticuremic syndrome plasmas induce apoptosis in restricted lineages of human microvascular endothelial cells Blood 1997 89: 1224\u20131234","journal-title":"Blood"},{"key":"BF1702849_CR16","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1182\/blood.V93.4.1264.404k16_1264_1270","volume":"93","author":"CT Dang","year":"1999","unstructured":"Dang CT, Magid MS, Weksler B et al. Enhanced endothelial cell apoptosis in splenic tissues of patients with thrombotic thrombocytopenic purpura Blood 1999 93: 1264\u20131270","journal-title":"Blood"},{"key":"BF1702849_CR17","doi-asserted-by":"publisher","first-page":"1578","DOI":"10.1056\/NEJM199811263392202","volume":"339","author":"M Furlan","year":"1998","unstructured":"Furlan M, Robles R, Galbusera M et al. Von Willebrand factor-cleaving protease in thrombotic thrombocytopenic purpura and the hemolytic-uremic syndrome New Engl J Med 1998 339: 1578\u20131584","journal-title":"New Engl J Med"},{"key":"BF1702849_CR18","doi-asserted-by":"publisher","first-page":"1585","DOI":"10.1056\/NEJM199811263392203","volume":"339","author":"H-M Tsai","year":"1998","unstructured":"Tsai H-M, Lian ECY . Antibodies to von-Willebrand factor-cleaving protease in acute thrombotic thrombocytopenic purpura New Engl J Med 1998 339: 1585\u20131594","journal-title":"New Engl J Med"},{"key":"BF1702849_CR19","doi-asserted-by":"crossref","first-page":"3798","DOI":"10.1182\/blood.V93.11.3798","volume":"93","author":"RM van der Plas","year":"1999","unstructured":"van der Plas RM, Schiphorst ME, Huizinga EG et al. von Willebrand factor proteolysis is deficient in classic, but not in bone marrow transplantation-associated, thrombotic thrombocytopenic purpura Blood 1999 93: 3798\u20133802","journal-title":"Blood"},{"key":"BF1702849_CR20","first-page":"2244","volume":"59","author":"L Oleksowicz","year":"1999","unstructured":"Oleksowicz L, Bhagwati N, DeLeon-Fernandez M . Deficient activity of vonWillebrand's factor-cleaving protease in patients with disseminated malignancies Cancer Res 1999 59: 2244\u20132250","journal-title":"Cancer Res"},{"key":"BF1702849_CR21","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1007\/s002770050364","volume":"76","author":"W N\u00fcrnberger","year":"1998","unstructured":"N\u00fcrnberger W, Michelmann I, Burdach S, G\u00f6bel U . Endothelial dysfunction after bone marrow transplantation: increase of soluble thrombomodulin and PAI-1 in patients with multiple transplant-related complications Ann Hematol 1998 76: 61\u201365","journal-title":"Ann Hematol"},{"key":"BF1702849_CR22","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1038\/sj.bmt.1701359","volume":"22","author":"RL Paquette","year":"1998","unstructured":"Paquette RL, Tran L, Landaw EM . Thrombotic microangiopathy following allogenic bone marrow transplantation is associated with intensive graft-versus-host disease prophylaxis Bone Marrow Transplant 1998 22: 351\u2013357","journal-title":"Bone Marrow Transplant"},{"key":"BF1702849_CR23","doi-asserted-by":"publisher","first-page":"896","DOI":"10.1046\/j.1537-2995.2000.40080896.x","volume":"40","author":"MA Rizvi","year":"2000","unstructured":"Rizvi MA, Vesely SK, George JN et al. Plasma exchange complications in 71 consecutive patients treated for clinically suspected thrombotic thrombocytopenic purpura-hemolytic uremic syndrome Transfusion 2000 40: 896\u2013901","journal-title":"Transfusion"},{"key":"BF1702849_CR24","first-page":"271","volume":"16","author":"R Sarode","year":"1995","unstructured":"Sarode R, McFarland JG, Flomenberg N et al. Therapeutic plasma exchange does not appear to be effective in the management of thrombotic thrombocytopenic purpura\/hemolytic uremic syndrome following bone marrow transplantation Bone Marrow Transplant 1995 16: 271\u2013275","journal-title":"Bone Marrow Transplant"},{"key":"BF1702849_CR25","first-page":"1019","volume":"22","author":"J Milone","year":"1998","unstructured":"Milone J, Napal J, Bordone J et al. Complete response in severe thrombotic microangiopathy post bone marrow transplantation (BMT-TM) after multiple plasmaphereses BoneMarrow Transplant 1998 22: 1019\u20131021","journal-title":"BoneMarrow Transplant"}],"container-title":["Bone Marrow Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/1702849","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/1702849.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/1702849.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,23]],"date-time":"2022-03-23T22:03:39Z","timestamp":1648073019000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/1702849"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,3,1]]},"references-count":25,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2001,3,1]]}},"alternative-id":["BF1702849"],"URL":"https:\/\/doi.org\/10.1038\/sj.bmt.1702849","relation":{},"ISSN":["0268-3369","1476-5365"],"issn-type":[{"value":"0268-3369","type":"print"},{"value":"1476-5365","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,3,1]]},"assertion":[{"value":"19 September 2000","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 January 2001","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 April 2001","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}