{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T16:58:23Z","timestamp":1771261103864,"version":"3.50.1"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2002,12,1]],"date-time":"2002-12-01T00:00:00Z","timestamp":1038700800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2002,12,1]],"date-time":"2002-12-01T00:00:00Z","timestamp":1038700800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Bone Marrow Transplant"],"published-print":{"date-parts":[[2002,12,1]]},"DOI":"10.1038\/sj.bmt.1703769","type":"journal-article","created":{"date-parts":[[2002,12,13]],"date-time":"2002-12-13T11:57:22Z","timestamp":1039780642000},"page":"861-866","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":51,"title":["G-CSF-primed haploidentical marrow transplantation without ex vivo T cell depletion: an excellent alternative for high-risk leukemia"],"prefix":"10.1038","volume":"30","author":[{"given":"S-Q","family":"Ji","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H-R","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H-X","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H-M","family":"Yan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Xue","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C-Q","family":"Xun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2002,12,12]]},"reference":[{"key":"BF1703769_CR1","doi-asserted-by":"publisher","first-page":"765","DOI":"10.1056\/NEJM198509263131301","volume":"313","author":"PG Beatty","year":"1985","unstructured":"Beatty PG, Glift RA, Mickelson EM et al. Marrow transplantation from related donor other than HLA-identical siblings New Engl J Med 1985 313: 765 771","journal-title":"New Engl J Med"},{"key":"BF1703769_CR2","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1056\/NEJM198901263200401","volume":"320","author":"C Anasetti","year":"1989","unstructured":"Anasetti C, Amos D, Beatty PG et al. Effect of HLA compatibility on engraftment of bone marrow transplants in patients with leukemia or lymphoma New Engl J Med 1989 320: 197 204","journal-title":"New Engl J Med"},{"key":"BF1703769_CR3","doi-asserted-by":"publisher","first-page":"887","DOI":"10.1097\/00007890-199410270-00005","volume":"58","author":"O Ringden","year":"1994","unstructured":"Ringden O, Remberger M, Aschan J et al. Long-term follow-up of a randomized trial comparing T cell depletion with a combination of methotrexate and cyclosporine in adult leukemic marrow transplant recipients Transplantation 1994 58: 887 891","journal-title":"Transplantation"},{"key":"BF1703769_CR4","doi-asserted-by":"publisher","first-page":"806","DOI":"10.7326\/0003-4819-108-6-806","volume":"108","author":"JM Goldman","year":"1988","unstructured":"Goldman JM, Gale PR, Horowitz MM et al. Bone marrow transplantation for chronic myelogenous leukemia in chronic phase: increased risk for relapse associated with T cell depletion Ann Intern Med 1988 108: 806 814","journal-title":"Ann Intern Med"},{"key":"BF1703769_CR5","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1111\/j.1365-2141.1992.tb08244.x","volume":"81","author":"DI Marks","year":"1992","unstructured":"Marks DI, Hughes TP, Szydlo R et al. HLA identical sibling donor bone marrow transplantation for chronic myeloid leukemia in the first chronic phase: influence of GVHD prophylaxis on outcome Br J Haematol 1992 81: 383 390","journal-title":"Br J Haematol"},{"key":"BF1703769_CR6","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1034\/j.1399-0012.2001.150503.x","volume":"15","author":"SQ Ji","year":"2001","unstructured":"Ji SQ, Chen HR, Xun CQ et al. The effect of G-CSF-stimulated donor marrow on engraftment and incidence of graft-versus-host disease in allogeneic bone marrow transplantation Clin Transplant 2001 15: 317 323","journal-title":"Clin Transplant"},{"key":"BF1703769_CR7","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1053\/bbmt.2002.v8.pm12064363","volume":"8","author":"SQ Ji","year":"2002","unstructured":"Ji SQ, Chen HR, Wang HX et al. Comparison outcome of allogeneic bone marrow transplantation with and without granulocyte colony stimulating factor (G-CSF) (lenograstim) donor marrow priming in patients with chronic myelogenous leukemia (CML) Biol Blood Marrow Transpl 2002 8: 261 267","journal-title":"Biol Blood Marrow Transpl"},{"key":"BF1703769_CR8","first-page":"825","volume":"15","author":"D Przepiorka","year":"1995","unstructured":"Przepiorka D, Weisdorf D, Martin P et al. 1994 Consensus Conference on Acute GVHD Grading Bone Marrow Transplant 1995 15: 825 828","journal-title":"Bone Marrow Transplant"},{"key":"BF1703769_CR9","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1002\/jcp.1040760111","volume":"76","author":"BL Pike","year":"1970","unstructured":"Pike BL, Robinson WA . Human bone marrow colony growth in agar gel J Cell Physiol 1970 76: 77 81","journal-title":"J Cell Physiol"},{"key":"BF1703769_CR10","doi-asserted-by":"crossref","first-page":"3864","DOI":"10.1182\/blood.V89.10.3864","volume":"89","author":"PJ Henslee-Downey","year":"1997","unstructured":"Henslee-Downey PJ, Abhyankar SH, Parrish RS et al. Use of partially mismatched related donors extends access to allogeneic marrow transplant Blood 1997 89: 3864 3872","journal-title":"Blood"},{"key":"BF1703769_CR11","first-page":"3","volume":"3","author":"RJ O'Reilly","year":"1988","unstructured":"O'Reilly RJ, Kernan NA, Canningham I et al. Allogeneic transplants depleted of T cell by soybean lectin agglutination and E-rosette depletion Bone Marrow Transplant 1988 3: 3 6","journal-title":"Bone Marrow Transplant"},{"key":"BF1703769_CR12","doi-asserted-by":"publisher","first-page":"434","DOI":"10.1016\/S1083-8791(00)70035-8","volume":"6","author":"JS Serody","year":"2000","unstructured":"Serody JS, Sparks CD, Lim S et al. Comparison of granulocyte colony-stimulating factor (G-CSF)-mobilized peripheral blood progenitor cells and G-CSF-stimulated bone marrow as a source of stem cells in HLA-matched sibling transplantation Biol Blood Marrow Transplant 2000 6: 434 440","journal-title":"Biol Blood Marrow Transplant"},{"key":"BF1703769_CR13","doi-asserted-by":"publisher","first-page":"1033","DOI":"10.1038\/sj.bmt.1701029","volume":"20","author":"LM Isola","year":"1997","unstructured":"Isola LM, Scigliano E, Skerrett D et al. A pilot study of allogeneic bone marrow transplantation using related donor stimulated with G-CSF Bone Marrow Transplant 1997 20: 1033 1037","journal-title":"Bone Marrow Transplant"},{"key":"BF1703769_CR14","doi-asserted-by":"publisher","first-page":"422","DOI":"10.1016\/S1083-8791(00)70033-4","volume":"6","author":"S Couban","year":"2000","unstructured":"Couban S, Messner HA, Andreou P et al. Bone marrow mobilized with granulocyte colony-stimulating factor in related allogeneic transplant recipients: a study of 29 patients Biol Blood Marrow Transplant 2000 6: 422 427","journal-title":"Biol Blood Marrow Transplant"},{"key":"BF1703769_CR15","doi-asserted-by":"crossref","first-page":"2794","DOI":"10.1182\/blood.V88.7.2794.bloodjournal8872794","volume":"88","author":"WI Bensinger","year":"1996","unstructured":"Bensinger WI, Clift R, Martin P et al. Allogeneic peripheral blood stem cell transplantation in patients with advanced hematological malignancies: a retrospective comparison with marrow transplantation Blood 1996 88: 2794 2800","journal-title":"Blood"},{"key":"BF1703769_CR16","first-page":"608a","volume":"94 (Suppl.\u20091)","author":"ST Darrant","year":"1999","unstructured":"Darrant ST, Morton AJ . A randomized trial of filgrastim (G-CSF) stimulated donor marrow versus peripheral blood for allogeneic transplantation: increased extensive chronic graft-versus-host disease following PBSC transplantation Blood 1999 94 (Suppl.\u20091): 608a","journal-title":"Blood"},{"key":"BF1703769_CR17","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1126\/science.1681588","volume":"254","author":"P Salgame","year":"1991","unstructured":"Salgame P, Abrams JS, Clayberger C et al. Differing lymphokine profiles of function subset of human CD4 and CD8 T cell clones Science 1991 254: 279 282","journal-title":"Science"},{"key":"BF1703769_CR18","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1089\/15258160050079407","volume":"9","author":"JL Ferrara","year":"2000","unstructured":"Ferrara JL . Pathogenesis of acute graft-versus-host disease: cytokines and cellular effectors J Hematother Stem Cell Res 2000 9: 299 306","journal-title":"J Hematother Stem Cell Res"},{"key":"BF1703769_CR19","doi-asserted-by":"publisher","first-page":"1278","DOI":"10.1097\/00007890-199611150-00018","volume":"62","author":"W Krenger","year":"1996","unstructured":"Krenger W, Cooke KR, Crawford JM et al. Transplantation of polarized type 2 donor T cells reduces mortality caused by experimental graft-versus-host disease Transplantation 1996 62: 1278 1285","journal-title":"Transplantation"},{"key":"BF1703769_CR20","doi-asserted-by":"crossref","first-page":"4422","DOI":"10.1182\/blood.V86.12.4422.bloodjournal86124422","volume":"86","author":"L Pan","year":"1995","unstructured":"Pan L, Delmonte J, Jalonen K et al. Pretreatment of donor mice with granulocyte colony-stimulating factor polarizes donor T lymphocytes toward type 2 cytokine production and reduces severity of experimental graft-versus-host disease Blood 1995 86: 4422 4429","journal-title":"Blood"},{"key":"BF1703769_CR21","doi-asserted-by":"publisher","first-page":"458","DOI":"10.1016\/S0301-472X(01)00613-0","volume":"29","author":"H Tayebi","year":"2001","unstructured":"Tayebi H, Kuttler F, Saas P et al. Effect of granulocyte colony-stimulating factor mobilization on phenotypical and functional properties of immune cells Exp Hematol 2001 29: 458 470","journal-title":"Exp Hematol"},{"key":"BF1703769_CR22","first-page":"193","volume":"7","author":"HJ Deeg","year":"1991","unstructured":"Deeg HJ, Spitzer TR, Cottler-Fax M et al. Conditioning-related toxicity and acute GVHD in patients given methotrexate\/cyclosporine prophylaxis Bone Marrow Transplant 1991 7: 193 198","journal-title":"Bone Marrow Transplant"},{"key":"BF1703769_CR23","doi-asserted-by":"crossref","first-page":"2360","DOI":"10.1182\/blood.V83.8.2360.2360","volume":"83","author":"CQ Xun","year":"1994","unstructured":"Xun CQ, Thompson JS, Jennings CD et al. Effect of total body irradiation, busulfan-cyclophosphamide or cyclophosphamide conditioning on inflammatory cytokine release in H-2 incompatible transplanted SCID mice Blood 1994 83: 2360 2367","journal-title":"Blood"},{"key":"BF1703769_CR24","doi-asserted-by":"crossref","first-page":"2964","DOI":"10.1182\/blood.V80.12.2964.2964","volume":"80","author":"JH Antin","year":"1992","unstructured":"Antin JH, Ferrara JLM . Cytokine dysregulation and acute GVHD Blood 1992 80: 2964 2969","journal-title":"Blood"},{"key":"BF1703769_CR25","doi-asserted-by":"crossref","first-page":"2462","DOI":"10.1182\/blood.V76.12.2462.2462","volume":"76","author":"HJ Kolb","year":"1990","unstructured":"Kolb HJ, Mittermuller J, Clemm C et al. Donor leukocyte transfusion for treatment of recurrent CML in marrow transplant patients Blood 1990 76: 2462 2465","journal-title":"Blood"},{"key":"BF1703769_CR26","doi-asserted-by":"publisher","first-page":"1529","DOI":"10.1056\/NEJM198106183042507","volume":"304","author":"PL Weiden","year":"1981","unstructured":"Weiden PL, Sullivan KM, Flournoy N et al. Antileukemic effect of chronic GVHD. Contribution to improved survival after allogeneic marrow transplantation New Engl J Med 1981 304: 1529 1533","journal-title":"New Engl J Med"},{"key":"BF1703769_CR27","doi-asserted-by":"publisher","first-page":"1217","DOI":"10.1038\/sj.bmt.1701793","volume":"23","author":"S Mineishi","year":"1999","unstructured":"Mineishi S, Longo WL, Atkinson ME et al. Addition of high-dose Ara-c to the BMT conditioning regimen reduces leukemia relapse without an increase in toxicity Bone Marrow Transplant 1999 23: 1217 1222","journal-title":"Bone Marrow Transplant"},{"key":"BF1703769_CR28","doi-asserted-by":"crossref","first-page":"3048","DOI":"10.1182\/blood.V89.8.3048","volume":"89","author":"R Storb","year":"1997","unstructured":"Storb R, Cong Y, Wanger JL et al. Stable mixed hematopoietic chimerism in DLA-identical littermate dogs given sublethal TBI before and pharmacological immunosuppression after marrow transplantation Blood 1997 89: 3048 3054","journal-title":"Blood"},{"key":"BF1703769_CR29","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1034\/j.1399-0012.2000.140204.x","volume":"14","author":"N Basara","year":"2000","unstructured":"Basara N, Blau WI, Kiehl MG et al. Mycophenolate mofetil for the prophylaxis of acute GVHD in HLA-mismatched bone marrow transplant patients Clin Transplant 2000 14: 121 126","journal-title":"Clin Transplant"}],"container-title":["Bone Marrow Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/1703769","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/1703769.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/1703769.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,23]],"date-time":"2022-03-23T23:21:13Z","timestamp":1648077673000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/1703769"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,12,1]]},"references-count":29,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2002,12,1]]}},"alternative-id":["BF1703769"],"URL":"https:\/\/doi.org\/10.1038\/sj.bmt.1703769","relation":{},"ISSN":["0268-3369","1476-5365"],"issn-type":[{"value":"0268-3369","type":"print"},{"value":"1476-5365","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,12,1]]},"assertion":[{"value":"24 January 2002","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 August 2002","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 December 2002","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}